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View Structure Prediction Details

Protein: PNG1
Organism: Saccharomyces cerevisiae
Length: 363 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PNG1.

Description E-value Query
Range
Subject
Range
PNG1_YEAST - Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase OS=Saccharomyces cerevisiae (strain ATCC...
PNG1 - Conserved peptide N-glycanase required for deglycosylation of misfolded glycoproteins during proteas...
gi|190407860 - gi|190407860|gb|EDV11125.1| peptide:N-glycanase [Saccharomyces cerevisiae RM11-1a]
gi|151942701 - gi|151942701|gb|EDN61047.1| PNGase [Saccharomyces cerevisiae YJM789]
0.0 [1..363] [1..363]
NGLY1 - N-glycanase 1
gi|123993667, gi... - gi|123999983|gb|ABM87500.1| N-glycanase 1 [synthetic construct], gi|123993667|gb|ABM84435.1| N-glyca...
0.0 [46..362] [165..473]
NGLY1_MOUSE - Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase OS=Mus musculus GN=Ngly1 PE=1 SV=2
0.0 [46..362] [162..470]
PNG1_ORYSA - Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase (EC 3.5.1.52) (Peptide:N-glycanase) - Or...
PNG1_ORYSJ - Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase OS=Oryza sativa subsp. japonica GN=PNG1 ...
6.0E-99 [13..357] [104..429]
gi|27808626 - gi|27808626|gb|AAO24593.1| At5g49570 [Arabidopsis thaliana]
1.0E-97 [13..362] [89..418]
png-1 - Thioredoxins status:Confirmed UniProt:Q9TW67 protein_id:CAB57916.1
4.0E-90 [52..363] [124..424]

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Predicted Domain #1
Region A:
Residues: [1-133]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGEVYEKNNI DFDSIAKMLL IKYKDFILSK FKKAAPVENI RFQNLVHTNQ FAQGVLGQSQ  60
   61 HLCTVYDNPS WHSIVLETLD LDLIYKNVDK EFAKDGHAEG ENIYTDYLVK ELLRYFKQDF 120
  121 FKWCNKPDCN HCG

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.601 0.344 peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity a.1.1 Globin-like
View Download 0.428 0.171 peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.411 0.007 peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity a.63.1 Apolipophorin-III
View Download 0.524 0.004 peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity a.68.1 Wiscott-Aldrich syndrome protein, WASP, C-terminal domain
View Download 0.582 N/A N/A a.168.1 GEF domain of SopE toxin
View Download 0.406 N/A N/A a.3.1 Cytochrome c
View Download 0.384 N/A N/A a.52.1 Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
View Download 0.382 N/A N/A a.142.1 PTS-regulatory domain, PRD
View Download 0.315 N/A N/A d.2.1 Lysozyme-like
View Download 0.308 N/A N/A a.24.14 FAT domain of focal adhesion kinase
View Download 0.291 N/A N/A e.34.1 NSP3 homodimer
View Download 0.288 N/A N/A a.74.1 Cyclin-like
View Download 0.281 N/A N/A a.19.1 Fertilization protein
View Download 0.273 N/A N/A a.1.1 Globin-like
View Download 0.273 N/A N/A a.48.1 N-terminal domain of cbl (N-cbl)
View Download 0.271 N/A N/A a.72.1 Functional domain of the splicing factor Prp18
View Download 0.258 N/A N/A d.122.1 ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
View Download 0.257 N/A N/A d.110.4 SNARE-like
View Download 0.257 N/A N/A a.24.4 Hemerythrin
View Download 0.255 N/A N/A a.29.5 alpha-ketoacid dehydrogenase kinase, N-terminal domain
View Download 0.253 N/A N/A a.25.2 Thermoplasma ferritin-like 4-helical bundle
View Download 0.252 N/A N/A a.75.1 Ribosomal protein S7
View Download 0.251 N/A N/A a.1.1 Globin-like
View Download 0.251 N/A N/A f.36.1 Neurotransmitter-gated ion-channel pransmembrane pore
View Download 0.244 N/A N/A c.95.1 Thiolase-like
View Download 0.243 N/A N/A f.13.1 Family A G protein-coupled receptor-like
View Download 0.239 N/A N/A a.7.8 GAT domain
View Download 0.238 N/A N/A d.56.1 GroEL-intermediate domain like
View Download 0.238 N/A N/A f.14.1 Voltage-gated potassium channels
View Download 0.237 N/A N/A a.47.2 t-snare proteins
View Download 0.237 N/A N/A a.1.1 Globin-like
View Download 0.234 N/A N/A a.148.1 Arp2/3 complex 21 kDa subunit ARPC3
View Download 0.226 N/A N/A c.2.1 NAD(P)-binding Rossmann-fold domains
View Download 0.216 N/A N/A f.18.1 F1F0 ATP synthase subunit A
View Download 0.216 N/A N/A a.7.1 Spectrin repeat
View Download 0.216 N/A N/A d.202.1 Transcription factor NusA, N-terminal domain
View Download 0.215 N/A N/A a.100.1 6-phosphogluconate dehydrogenase C-terminal domain-like
View Download 0.207 N/A N/A d.162.1 LDH C-terminal domain-like
View Download 0.206 N/A N/A a.1.1 Globin-like
View Download 0.206 N/A N/A a.24.9 alpha-catenin/vinculin
View Download 0.204 N/A N/A a.45.1 Glutathione S-transferase (GST), C-terminal domain

Predicted functions:

Term Confidence Notes
cysteine-type peptidase activity 3.05412701733177 bayes_pls_golite062009
peptidase activity 2.99092799770282 bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides 2.70509346529146 bayes_pls_golite062009
binding 2.49172648273202 bayes_pls_golite062009
hydrolase activity 2.29464693834116 bayes_pls_golite062009
cysteine-type endopeptidase activity 1.95802900199539 bayes_pls_golite062009
small conjugating protein-specific protease activity 1.90904708303381 bayes_pls_golite062009
endopeptidase activity 1.64915398352449 bayes_pls_golite062009
SUMO-specific protease activity 1.44953547163733 bayes_pls_golite062009
nucleic acid binding 1.38318152877128 bayes_pls_golite062009
peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity 1.3714358594696 bayes_pls_golite062009
transcription regulator activity 1.34325826373515 bayes_pls_golite062009
DNA binding 1.31096468235949 bayes_pls_golite062009
ubiquitin-specific protease activity 1.28746642057417 bayes_pls_golite062009
catalytic activity 1.05972260874031 bayes_pls_golite062009
protein binding 0.774177093888744 bayes_pls_golite062009
transcription factor activity 0.656405451523439 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.218846845851145 bayes_pls_golite062009
calcium-dependent cysteine-type endopeptidase activity 0.196538841514154 bayes_pls_golite062009
transferase activity 0.0852393573521809 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [134-277]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QNTSENMTPL GSQGPNGEES KFNCGTVEIY KCNRCGNITR FPRYNDPIKL LETRKGRCGE  60
   61 WCNLFTLILK SFGLDVRYVW NREDHVWCEY FSNFLNRWVH VDSCEQSFDQ PYIYSINWNK 120
  121 KMSYCIAFGK DGVVDVSKRY ILQN

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 15.443697
Match: PF01841
Description: Transglutaminase-like superfamily

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [278-363]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ELPRDQIKEE DLKFLCQFIT KRLRYSLNDD EIYQLACRDE QEQIELIRGK TQETKSESVS  60
   61 AASKSSNRGR ESGSADWKAQ RGEDGK

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.254 0.086 peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity a.21.1 HMG-box
View Download 0.318 0.074 peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity a.61.1 Retroviral matrix proteins
View Download 0.227 0.053 peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity a.28.1 ACP-like
View Download 0.263 0.007 peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity a.144.2 Ribosomal protein L20
View Download 0.229 N/A N/A a.76.1 Iron-dependent represor protein, dimerization domain
View Download 0.225 N/A N/A d.58.5 GlnB-like
View Download 0.222 N/A N/A a.163.1 Crustacean CHH/MIH/GIH neurohormone
View Download 0.203 N/A N/A a.60.2 RuvA domain 2-like
View Download 0.201 N/A N/A d.58.10 Acylphosphatase-like


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle