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View Structure Prediction Details

Protein: ELP3
Organism: Saccharomyces cerevisiae
Length: 557 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ELP3.

Description E-value Query
Range
Subject
Range
ELP3 - Subunit of Elongator complex, which is required for modification of wobble nucleosides in tRNA; exhi...
ELP3_YEAST - Elongator complex protein 3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ELP3 PE=1 SV...
gi|190407869 - gi|190407869|gb|EDV11134.1| RNA polymerase II Elongator subunit [Saccharomyces cerevisiae RM11-1a]
gi|151942711 - gi|151942711|gb|EDN61057.1| RNA polymerase II Elongator subunit [Saccharomyces cerevisiae YJM789]
0.0 [1..557] [1..557]
gi|32412484, gi|... - gi|7635787|emb|CAB88553.1| probable histone acetyltransferase [Neurospora crassa], gi|32412484|ref|X...
gi|85103762 - gi|85103762|ref|XP_961595.1| hypothetical protein NCU01229 [Neurospora crassa OR74A]
0.0 [14..557] [16..563]
HGNC:20696|MIM:6... - protein 3 homolog (S. cerevisiae)
gi|208966202, gi... - gi|208966202|dbj|BAG73115.1| elongation protein 3 homolog [synthetic construct], gi|117646792|emb|CA...
ELP3 - elongation protein 3 homolog (S. cerevisiae)
0.0 [16..557] [9..546]
ELP3_MOUSE - Elongator complex protein 3 OS=Mus musculus GN=Elp3 PE=1 SV=1
0.0 [16..557] [9..546]
ELP3_SCHPO - Probable elongator complex protein 3 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=elp3 ...
SPAC29A4.20 - RNA polymerase II elongator complex, histone acetyltransferase subunit
0.0 [22..557] [10..544]
gi|220957548, gi... - gi|220957548|gb|ACL91317.1| Elp3-PA [synthetic construct], gi|220948416|gb|ACL86751.1| Elp3-PA [synt...
Elp3-PA - The gene Elp3 is referred to in FlyBase by the symbol Dmel\Elp3 (CG15433, FBgn0031604). It is a prot...
0.0 [15..557] [10..548]
ELP3_ARATH - Elongator complex protein 3 OS=Arabidopsis thaliana GN=HAG3 PE=1 SV=1
0.0 [7..557] [18..564]
CE15439 - WBGene00014123 Yeast LPG22P protein like status:Partially_confirmed TR:Q23651 protein_id:CAB01454.1
0.0 [22..557] [18..549]

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Predicted Domain #1
Region A:
Residues: [1-423]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MARHGKGPKT NKKKLAPEKE RFIQCCADIT LELTDSLTSG TTREINLNGL ITKYSKKYKL  60
   61 KQQPRLTDII NSIPDQYKKY LLPKLKAKPV RTASGIAVVA VMCKPHRCPH IAYTGNICVY 120
  121 CPGGPDSDFE YSTQSYTGYE PTSMRAIRAR YDPYEQARGR VEQLKQLGHS IDKVEYVLMG 180
  181 GTFMSLPKEY REDFIVKLHN ALSGFNGNDI DEAILYSQQS LTKCVGITIE TRPDYCTQTH 240
  241 LDDMLKYGCT RLEIGVQSLY EDVARDTNRG HTVRSVCETF AVSKDAGYKV VSHMMPDLPN 300
  301 VGMERDIEQF KEYFENPDFR TDGLKIYPTL VIRGTGLYEL WKTGRYKSYS ANALVDLVAR 360
  361 ILALVPPWTR IYRVQRDIPM PLVTSGVDNG NLRELALARM KDLGTTCRDV RTREVGIQEV 420
  421 HHK

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term Confidence Notes
binding 1.62614606868017 bayes_pls_golite062009
catalytic activity 1.48331922124015 bayes_pls_golite062009
transferase activity 1.38870107531698 bayes_pls_golite062009
protein binding 0.374124957429525 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [424-557]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VQPDQVELIR RDYYANGGWE TFLSYEDPKK DILIGLLRLR KASKKYTYRK EFTSQRTSIV  60
   61 RELHVYGSVV PLHSRDPRKF QHQGFGTLLM EEAERIAKEE HGSEKISVIS GVGVRNYYGK 120
  121 LGYELDGPYM SKRI

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 6.508638
Match: PF00583
Description: Acetyltransferase (GNAT) family

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term Confidence Notes
transferase activity 3.26226130947208 bayes_pls_golite062009
N-acyltransferase activity 3.22332766762816 bayes_pls_golite062009
N-acetyltransferase activity 3.16285222477063 bayes_pls_golite062009
histone acetyltransferase activity 3.09883679214009 bayes_pls_golite062009
lysine N-acetyltransferase activity 3.09883679214009 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 3.06288276492113 bayes_pls_golite062009
acetyltransferase activity 2.29329191833529 bayes_pls_golite062009
transcription regulator activity 2.26346740872821 bayes_pls_golite062009
nucleic acid binding 2.14720849412601 bayes_pls_golite062009
transferase activity, transferring acyl groups 2.05664878927078 bayes_pls_golite062009
catalytic activity 1.823104805379 bayes_pls_golite062009
binding 1.30356860355657 bayes_pls_golite062009
transcription coactivator activity 1.05620338082006 bayes_pls_golite062009
transcription factor binding 0.999468823887739 bayes_pls_golite062009
transferase activity, transferring acyl groups other than amino-acyl groups 0.934738369878547 bayes_pls_golite062009
acyltransferase activity 0.930618573930377 bayes_pls_golite062009
transcription activator activity 0.800725992277502 bayes_pls_golite062009
0.720242802910078 bayes_pls_golite062009
RNA polymerase II transcription factor activity 0.60912193595326 bayes_pls_golite062009
RNA binding 0.314555310175452 bayes_pls_golite062009
transcription cofactor activity 0.207688916644661 bayes_pls_golite062009
protein binding 0.116359302536336 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle