Protein: | HST2 |
Organism: | Saccharomyces cerevisiae |
Length: | 357 amino acids |
Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for HST2.
Description | E-value | Query Range |
Subject Range |
|
2.0E-96 | [1..357] | [1..357] |
|
2.0E-83 | [7..334] | [22..352] |
|
4.0E-81 | [7..334] | [22..352] |
|
9.0E-80 | [2..347] | [5..322] |
Region A: Residues: [1-43] |
1 11 21 31 41 51 | | | | | | 1 MSVSTASTEM SVRKIAAHMK SNPNAKVIFM VGAGISTSCG IPD |
Region B: Residues: [88-137] |
1 11 21 31 41 51 | | | | | | 1 PGNFRPSKFH YLLKLFQDKD VLKRVYTQNI DTLERQAGVK DDLIIEAHGS |
Region C: Residues: [189-357] |
1 11 21 31 41 51 | | | | | | 1 PDSFSETWLN DSEWLREKIT TSGKHPQQPL VIVVGTSLAV YPFASLPEEI PRKVKRVLCN 60 61 LETVGDFKAN KRPTDLIVHQ YSDEFAEQLV EELGWQEDFE KILTAQGGMG DNSKEQLLEI 120 121 VHDLENLSLD QSEHESADKK DKKLQRLNGH DSDEDGASNS SSSQKAAKE |
Detection Method: | ![]() |
Confidence: | 662.9897 |
Match: | 1j8fA_ |
Description: | Sirt2 histone deacetylase |
Matching Structure (courtesy of the PDB):![]() |
Term | Confidence | Notes |
protein deacetylase activity | 9.15022242957651 | bayes_pls_golite062009 |
histone deacetylase activity | 9.04876491350231 | bayes_pls_golite062009 |
NAD-dependent protein deacetylase activity | 8.13038616303736 | bayes_pls_golite062009 |
NAD-dependent histone deacetylase activity | 8.13038616303736 | bayes_pls_golite062009 |
deacetylase activity | 8.11496387956068 | bayes_pls_golite062009 |
histone deacetylase activity (H3-K14 specific) | 6.02509672218091 | bayes_pls_golite062009 |
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides | 5.83127897351395 | bayes_pls_golite062009 |
NAD-dependent histone deacetylase activity (H3-K9 specific) | 5.29340754009793 | bayes_pls_golite062009 |
NAD-dependent histone deacetylase activity (H3-K14 specific) | 5.29340754009793 | bayes_pls_golite062009 |
NAD-dependent histone deacetylase activity (H4-K16 specific) | 4.51070381823692 | bayes_pls_golite062009 |
histone deacetylase activity (H3-K9 specific) | 3.4896257195243 | bayes_pls_golite062009 |
transcription regulator activity | 2.9155913558118 | bayes_pls_golite062009 |
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds | 2.82468859281133 | bayes_pls_golite062009 |
DNA binding | 2.43141001866996 | bayes_pls_golite062009 |
nucleic acid binding | 2.41433477472968 | bayes_pls_golite062009 |
transcription repressor activity | 2.24657784428979 | bayes_pls_golite062009 |
binding | 2.06552694538163 | bayes_pls_golite062009 |
histone binding | 1.71445510915336 | bayes_pls_golite062009 |
transcription corepressor activity | 1.64212790017753 | bayes_pls_golite062009 |
protein binding | 1.52593340148652 | bayes_pls_golite062009 |
nucleosome binding | 1.5125174755597 | bayes_pls_golite062009 |
hydrolase activity | 1.43067365161346 | bayes_pls_golite062009 |
transcription factor activity | 1.30143289828088 | bayes_pls_golite062009 |
transcription factor binding | 1.14766678956419 | bayes_pls_golite062009 |
tubulin deacetylase activity | 1.11434618720209 | bayes_pls_golite062009 |
catalytic activity | 0.739210399081789 | bayes_pls_golite062009 |
transcription cofactor activity | 0.54005617175343 | bayes_pls_golite062009 |
transferase activity | 0.483523935618287 | bayes_pls_golite062009 |
NAD+ ADP-ribosyltransferase activity | 0.0099486881187274 | bayes_pls_golite062009 |
Region A: Residues: [44-87] |
1 11 21 31 41 51 | | | | | | 1 FRSPGTGLYH NLARLKLPYP EAVFDVDFFQ SDPLPFYTLA KELY |
Region B: Residues: [138-188] |
1 11 21 31 41 51 | | | | | | 1 FAHCHCIGCG KVYPPQVFKS KLAEHPIKDF VKCDVCGELV KPAIVFFGED L |
Detection Method: | ![]() |
Confidence: | 662.9897 |
Match: | 1j8fA_ |
Description: | Sirt2 histone deacetylase |
Matching Structure (courtesy of the PDB):![]() |