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View Structure Prediction Details

Protein: SNF8
Organism: Saccharomyces cerevisiae
Length: 233 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SNF8.

Description E-value Query
Range
Subject
Range
gi|5670007 - gi|5670007|gb|AAD46560.1| ELL complex EAP30 subunit [Homo sapiens]
5.0E-95 [4..230] [8..241]
gi|120577573, gi... - gi|147907030|ref|NP_001091233.1| hypothetical protein LOC100037026 [Xenopus laevis], gi|120577573|gb...
SNF8_MOUSE - Vacuolar-sorting protein SNF8 OS=Mus musculus GN=Snf8 PE=1 SV=1
2.0E-94 [4..230] [8..241]
SNF8_YEAST - Vacuolar-sorting protein SNF8 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SNF8 PE=1 ...
gi|207340436 - gi|207340436|gb|EDZ68785.1| YPL002Cp-like protein [Saccharomyces cerevisiae AWRI1631]
gi|190407943 - gi|190407943|gb|EDV11208.1| vacuolar sorting protein SNF8 [Saccharomyces cerevisiae RM11-1a]
gi|151942790 - gi|151942790|gb|EDN61136.1| component of the ESCRT-II complex [Saccharomyces cerevisiae YJM789]
SNF8 - Component of the ESCRT-II complex, which is involved in ubiquitin-dependent sorting of proteins into...
1.0E-92 [1..233] [1..233]
lsn-PA - The gene larsen is referred to in FlyBase by the symbol Dmel\lsn (CG6637, FBgn0260940). It is a prot...
6.0E-92 [2..232] [3..246]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
4.0E-91 [2..232] [101..342]
gi|21294747, gi|... - gi|31204723|ref|XP_311310.1| AGAP000771-PA [Anopheles gambiae str. PEST], gi|21294747|gb|EAA06892.1|...
AGAP000771-PA - Vacuolar-sorting protein SNF8|protein_coding|X:13860780:13861688:-1|gene:AGAP000771
8.0E-90 [2..233] [3..246]
gi|85109821 - gi|85109821|ref|XP_963104.1| hypothetical protein NCU07843 [Neurospora crassa OR74A]
gi|28924756, gi|... - gi|32416142|ref|XP_328549.1| hypothetical protein [Neurospora crassa], gi|28924756|gb|EAA33868.1| hy...
5.0E-83 [2..231] [7..258]

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Predicted Domain #1
Region A:
Residues: [1-233]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKQFGLAAFD ELKDGKYNDV NKTILEKQSV ELRDQLMVFQ ERLVEFAKKH NSELQASPEF  60
   61 RSKFMHMCSS IGIDPLSLFD RDKHLFTVND FYYEVCLKVI EICRQTKDMN GGVISFQELE 120
  121 KVHFRKLNVG LDDLEKSIDM LKSLECFEIF QIRGKKFLRS VPNELTSDQT KILEICSILG 180
  181 YSSISLLKAN LGWEAVRSKS ALDEMVANGL LWIDYQGGAE ALYWDPSWIT RQL

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term Confidence Notes
transcription regulator activity 5.55329976718261 bayes_pls_golite062009
DNA binding 5.08959163553491 bayes_pls_golite062009
nucleic acid binding 4.99681957904233 bayes_pls_golite062009
transcription factor activity 4.33152142980289 bayes_pls_golite062009
transcription repressor activity 3.85678231380989 bayes_pls_golite062009
binding 3.52874320222492 bayes_pls_golite062009
RNA polymerase II transcription factor activity 2.60738445921725 bayes_pls_golite062009
sequence-specific DNA binding 2.48053910222825 bayes_pls_golite062009
transcription activator activity 2.37668609508629 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 1.2723726467408 bayes_pls_golite062009
specific transcriptional repressor activity 0.96257232341735 bayes_pls_golite062009
transcription factor binding 0.85714789329232 bayes_pls_golite062009
protein binding 0.753698599635855 bayes_pls_golite062009
structure-specific DNA binding 0.750801486608713 bayes_pls_golite062009
specific RNA polymerase II transcription factor activity 0.66743181561551 bayes_pls_golite062009
signal transducer activity 0.574575108509588 bayes_pls_golite062009
molecular transducer activity 0.574575108509588 bayes_pls_golite062009
transcription corepressor activity 0.322180400748724 bayes_pls_golite062009
RNA polymerase II transcription factor activity, enhancer binding 0.23177057841536 bayes_pls_golite062009
hydrolase activity 0.140191206949582 bayes_pls_golite062009
ubiquitin-protein ligase activity 0.136726704233672 bayes_pls_golite062009
small conjugating protein ligase activity 0.118016217031359 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle