






| Protein: | APC5 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 685 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for APC5.
| Description | E-value | Query Range |
Subject Range |
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0.0 | [1..685] | [1..685] |
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0.0 | [12..400] | [4..356] |
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2.0E-99 | [13..388] | [13..339] |
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4.0E-97 | [8..408] | [25..366] |
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5.0E-80 | [14..393] | [46..388] |
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3.0E-73 | [8..346] | [13..293] |
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Region A: Residues: [1-223] |
1 11 21 31 41 51
| | | | | |
1 MSKYGPLGIT NFITPYDLCI LILIHAHCSQ DNGISVPTAV FLRLISPTRP SLEWNPLLKD 60
61 NSNLRSSSIV PPPVLPILDN IIRILLDDKD GNKIALTLMG YLEAINGLDS INRLMMDLEK 120
121 NCLVNNYRSM KMRTTSTRRQ MTRASFLGTF LSTCIRKYQI GDFEMRETIW INLQNFKTVF 180
181 KHTPLWLRFK DNVHIQKVKN CLLANDEISV EDQQMVEFFQ HFN
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Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
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Region A: Residues: [224-282] |
1 11 21 31 41 51
| | | | | |
1 NGNDADSKTM NEENYGTLIS IQHLQSIVNR QIVNWLDNTE FNLMGQEETS STYEEQSGL
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Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
| Term | Confidence | Notes |
| ubiquitin-protein ligase activity | 6.60409233943418 | bayes_pls_golite062009 |
| small conjugating protein ligase activity | 6.34821407430872 | bayes_pls_golite062009 |
| acid-amino acid ligase activity | 5.66913998827366 | bayes_pls_golite062009 |
| ligase activity, forming carbon-nitrogen bonds | 4.89633630562107 | bayes_pls_golite062009 |
| binding | 2.50062202757362 | bayes_pls_golite062009 |
| ligase activity | 1.73009430374312 | bayes_pls_golite062009 |
| protein binding | 1.72061787550863 | bayes_pls_golite062009 |
| hydrolase activity | 0.63851966218836 | bayes_pls_golite062009 |
| nucleic acid binding | 0.437277381081288 | bayes_pls_golite062009 |
| transcription regulator activity | 0.198767743012145 | bayes_pls_golite062009 |
| DNA binding | 0.186035324819401 | bayes_pls_golite062009 |
|
Region A: Residues: [283-385] |
1 11 21 31 41 51
| | | | | |
1 VFDLLDTLSL NDATKFPLIF ILKYLEAIKE NSYQTALDSL HNYFDYKSTG NSQNYFHISL 60
61 LSLATFHSSF NECDAAINSF EEATRIAREN KDMETLNLIM IWI
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| Detection Method: | |
| Confidence: | 9.5 |
| Match: | 1hz4A |
| Description: | Transcription factor MalT domain III |
Matching Structure (courtesy of the PDB):![]() |
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Region A: Residues: [386-512] |
1 11 21 31 41 51
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1 INFIEVHPEY ANRFYITVEQ IIKYLKNSSD VEDANIFSNA YKFETLLSMV KESKTAEVSS 60
61 SLLKFMAITL QNVPSQNFDL FQSLVSYEVK FWKELGYESI SDVYEKFLSK TSSSSLRNYD 120
121 SSIINQD
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| Detection Method: | |
| Confidence: | 9.5 |
| Match: | 1hz4A |
| Description: | Transcription factor MalT domain III |
Matching Structure (courtesy of the PDB):![]() |
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|
Region A: Residues: [513-685] |
1 11 21 31 41 51
| | | | | |
1 IKVAFKALEE DDFLKVKQYL LKSESLELDY DQKINLKYLR VKYLVKIGDY DLSMRLINQY 60
61 VKECCEEVAD SNWRFKFEIE SINVLLLSDV GIRSLPKIIK LIDEYKEIGN PLRCVILLLK 120
121 LCEVLIQVGK SMEAECLISC NLSTILEFPF VRKKTDELLE SLSVEEDRDV QMT
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| Detection Method: | |
| Confidence: | 9.5 |
| Match: | 1hz4A |
| Description: | Transcription factor MalT domain III |
Matching Structure (courtesy of the PDB):![]() |
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