| Protein: | ACC1 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 2233 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ACC1.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [738..1808] | [1..1071] |
|
|
0.0 | [926..2198] | [867..2080] |
|
|
0.0 | [738..1808] | [1..1078] |
|
|
0.0 | [39..2232] | [98..2315] |
|
|
0.0 | [36..2232] | [94..2337] |
|
|
0.0 | [19..1478] | [301..1712] |
|
|
0.0 | [1..2233] | [1..2237] |
|
Region A: Residues: [1-174] |
1 11 21 31 41 51
| | | | | |
1 MSEESLFESS PQKMEYEITN YSERHTELPG HFIGLNTVDK LEESPLRDFV KSHGGHTVIS 60
61 KILIANNGIA AVKEIRSVRK WAYETFGDDR TVQFVAMATP EDLEANAEYI RMADQYIEVP 120
121 GGTNNNNYAN VDLIVDIAER ADVDAVWAGW GHASENPLLP EKLSQSKRKV IFIG
|
| Detection Method: |  |
| Confidence: | 700.228787 |
| Match: | 1bncA_ |
| Description: | Biotin carboxylase subunit of acetyl-CoA carboxylase (BC), C-domain; Biotin carboxylase subunit of acetyl-CoA carboxylase, (BC), N-domain; Biotin carboxylase subunit of acetyl-CoA carboxylase (BC), domain 2 |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| acetyl-CoA carboxylase activity | 7.97944928068929 | bayes_pls_golite062009 |
| CoA carboxylase activity | 7.26031530137805 | bayes_pls_golite062009 |
| ligase activity, forming carbon-carbon bonds | 7.11064677387039 | bayes_pls_golite062009 |
| biotin carboxylase activity | 6.9547407447638 | bayes_pls_golite062009 |
| ligase activity | 6.37416374794432 | bayes_pls_golite062009 |
| carbamoyl-phosphate synthase activity | 4.25267317906061 | bayes_pls_golite062009 |
| carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity | 4.17451795830682 | bayes_pls_golite062009 |
| succinate-CoA ligase activity | 3.60521632399322 | bayes_pls_golite062009 |
| CoA-ligase activity | 3.23896308753196 | bayes_pls_golite062009 |
| acid-thiol ligase activity | 3.04454283840859 | bayes_pls_golite062009 |
| methylcrotonoyl-CoA carboxylase activity | 2.98357921316004 | bayes_pls_golite062009 |
| glutathione synthase activity | 2.75320638765219 | bayes_pls_golite062009 |
| ligase activity, forming carbon-sulfur bonds | 2.73831154716701 | bayes_pls_golite062009 |
| ligase activity, forming carbon-nitrogen bonds | 1.74185999556024 | bayes_pls_golite062009 |
| glutathione binding | 1.60917807172757 | bayes_pls_golite062009 |
| phosphoribosylaminoimidazole carboxylase activity | 1.57708889650281 | bayes_pls_golite062009 |
| succinate-CoA ligase (ADP-forming) activity | 1.55053478055591 | bayes_pls_golite062009 |
| binding | 1.51238789441513 | bayes_pls_golite062009 |
| acid-amino acid ligase activity | 1.40905042897991 | bayes_pls_golite062009 |
| transporter activity | 1.29381792295125 | bayes_pls_golite062009 |
| carbon-nitrogen ligase activity, with glutamine as amido-N-donor | 1.11645327303429 | bayes_pls_golite062009 |
| catalytic activity | 1.08688404807699 | bayes_pls_golite062009 |
| phosphoribosylamine-glycine ligase activity | 1.04915286326924 | bayes_pls_golite062009 |
| propionyl-CoA carboxylase activity | 0.643677287269589 | bayes_pls_golite062009 |
| hydrolase activity | 0.543813086594651 | bayes_pls_golite062009 |
| protein binding | 0.455938814211606 | bayes_pls_golite062009 |
| succinate-CoA ligase (GDP-forming) activity | 0.34559667514727 | bayes_pls_golite062009 |
|
Region A: Residues: [175-201] |
1 11 21 31 41 51
| | | | | |
1 PPGNAMRSLG DKISSTIVAQ SAKVPCI
|
|
Region B: Residues: [293-318] |
1 11 21 31 41 51
| | | | | |
1 AGRARHLEVQ LLADQYGTNI SLFGRD
|
|
Region C: Residues: [332-452] |
1 11 21 31 41 51
| | | | | |
1 APVTIAKAET FHEMEKAAVR LGKLVGYVSA GTVEYLYSHD DGKFYFLELN PRLQVEHPTT 60
61 EMVSGVNLPA AQLQIAMGIP MHRISDIRTL YGMNPHSASE IDFEFKTQDA TKKQRRPIPK 120
121 G
|
| Detection Method: | |
| Confidence: | 700.228787 |
| Match: | 1bncA_ |
| Description: | Biotin carboxylase subunit of acetyl-CoA carboxylase (BC), C-domain; Biotin carboxylase subunit of acetyl-CoA carboxylase, (BC), N-domain; Biotin carboxylase subunit of acetyl-CoA carboxylase (BC), domain 2 |
| Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [202-292] |
1 11 21 31 41 51
| | | | | |
1 PWSGTGVDTV HVDEKTGLVS VDDDIYQKGC CTSPEDGLQK AKRIGFPVMI KASEGGGGKG 60
61 IRQVEREEDF IALYHQAANE IPGSPIFIMK L
|
|
Region B: Residues: [319-331] |
1 11 21 31 41 51
| | | | | |
1 CSVQRRHQKI IEE
|
|
Region C: Residues: [453-603] |
1 11 21 31 41 51
| | | | | |
1 HCTACRITSE DPNDGFKPSG GTLHELNFRS SSNVWGYFSV GNNGNIHSFS DSQFGHIFAF 60
61 GENRQASRKH MVVALKELSI RGDFRTTVEY LIKLLETEDF EDNTITTGWL DDLITHKMTA 120
121 EKPDPTLAVI CGAATKAFLA SEEARHKYIE S
|
| Detection Method: | |
| Confidence: | 700.228787 |
| Match: | 1bncA_ |
| Description: | Biotin carboxylase subunit of acetyl-CoA carboxylase (BC), C-domain; Biotin carboxylase subunit of acetyl-CoA carboxylase, (BC), N-domain; Biotin carboxylase subunit of acetyl-CoA carboxylase (BC), domain 2 |
| Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [604-695] |
1 11 21 31 41 51
| | | | | |
1 LQKGQVLSKD LLQTMFPVDF IHEGKRYKFT VAKSGNDRYT LFINGSKCDI ILRQLSDGGL 60
61 LIAIGGKSHT IYWKEEVAAT RLSVDSMTTL LE
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
| MCM Score |
SCOP Match |
SCOP Description | ||
| View | Download | 0.959 | b.61.2 | Metalloprotease inhibitor |
|
Region A: Residues: [696-781] |
1 11 21 31 41 51
| | | | | |
1 VENDPTQLRT PSPGKLVKFL VENGEHIIKG QPYAEIEVMK MQMPLVSQEN GIVQLLKQPG 60
61 STIVAGDIMA IMTLDDPSKV KHALPF
|
| Detection Method: | |
| Confidence: | 12.522879 |
| Match: | 1dczA_ |
| Description: | Biotin carboxyl carrier domain of transcarboxylase (TC 1.3S) |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [782-989] |
1 11 21 31 41 51
| | | | | |
1 EGMLPDFGSP VIEGTKPAYK FKSLVSTLEN ILKGYDNQVI MNASLQQLIE VLRNPKLPYS 60
61 EWKLHISALH SRLPAKLDEQ MEELVARSLR RGAVFPARQL SKLIDMAVKN PEYNPDKLLG 120
121 AVVEPLADIA HKYSNGLEAH EHSIFVHFLE EYYEVEKLFN GPNVREENII LKLRDENPKD 180
181 LDKVALTVLS HSKVSAKNNL ILAILKHY
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [990-1091] |
1 11 21 31 41 51
| | | | | |
1 QPLCKLSSKV SAIFSTPLQH IVELESKATA KVALQAREIL IQGALPSVKE RTEQIEHILK 60
61 SSVVKVAYGS SNPKRSEPDL NILKDLIDSN YVVFDVLLQF LT
|
| Detection Method: | |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
| MCM Score |
GO Score |
GO Term |
SCOP Match |
SCOP Description | ||
| View | Download | 0.867 | 0.072 | biotin carboxylase activity | a.24.13 | Domain of the SRP/SRP receptor G-proteins |
|
Region A: Residues: [1092-1154] |
1 11 21 31 41 51
| | | | | |
1 HQDPVVTAAA AQVYIRRAYR AYTIGDIRVH EGVTVPIVEW KFQLPSAAFS TFPTVKSKMG 60
61 MNR
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [1155-1328] |
1 11 21 31 41 51
| | | | | |
1 AVSVSDLSYV ANSQSSPLRE GILMAVDHLD DVDEILSQSL EVIPRHQSSS NGPAPDRSGS 60
61 SASLSNVANV CVASTEGFES EEEILVRLRE ILDLNKQELI NASIRRITFM FGFKDGSYPK 120
121 YYTFNGPNYN ENETIRHIEP ALAFQLELGR LSNFNIKPIF TDNRNIHVYE AVSK
|
| Detection Method: | |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [1329-1527] |
1 11 21 31 41 51
| | | | | |
1 TSPLDKRFFT RGIIRTGHIR DDISIQEYLT SEANRLMSDI LDNLEVTDTS NSDLNHIFIN 60
61 FIAVFDISPE DVEAAFGGFL ERFGKRLLRL RVSSAEIRII IKDPQTGAPV PLRALINNVS 120
121 GYVIKTEMYT EVKNAKGEWV FKSLGKPGSM HLRPIATPYP VKEWLQPKRY KAHLMGTTYV 180
181 YDFPELFRQA SSSQWKNFS
|
| Detection Method: | |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [1528-2146] |
1 11 21 31 41 51
| | | | | |
1 ADVKLTDDFF ISNELIEDEN GELTEVEREP GANAIGMVAF KITVKTPEYP RGRQFVVVAN 60
61 DITFKIGSFG PQEDEFFNKV TEYARKRGIP RIYLAANSGA RIGMAEEIVP LFQVAWNDAA 120
121 NPDKGFQYLY LTSEGMETLK KFDKENSVLT ERTVINGEER FVIKTIIGSE DGLGVECLRG 180
181 SGLIAGATSR AYHDIFTITL VTCRSVGIGA YLVRLGQRAI QVEGQPIILT GAPAINKMLG 240
241 REVYTSNLQL GGTQIMYNNG VSHLTAVDDL AGVEKIVEWM SYVPAKRNMP VPILETKDTW 300
301 DRPVDFTPTN DETYDVRWMI EGRETESGFE YGLFDKGSFF ETLSGWAKGV VVGRARLGGI 360
361 PLGVIGVETR TVENLIPADP ANPNSAETLI QEPGQVWHPN SAFKTAQAIN DFNNGEQLPM 420
421 MILANWRGFS GGQRDMFNEV LKYGSFIVDA LVDYKQPIII YIPPTGELRG GSWVVVDPTI 480
481 NADQMEMYAD VNARAGVLEP QGMVGIKFRR EKLLDTMNRL DDKYRELRSQ LSNKSLAPEV 540
541 HQQISKQLAD RERELLPIYG QISLQFADLH DRSSRMVAKG VISKELEWTE ARRFFFWRLR 600
601 RRLNEEYLIK RLSHQVGEA
|
| Detection Method: | |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [2147-2233] |
1 11 21 31 41 51
| | | | | |
1 SRLEKIARIR SWYPASVDHE DDRQVATWIE ENYKTLDDKL KGLKLESFAQ DLAKKIRSDH 60
61 DNAIDGLSEV IKMLSTDDKE KLLKTLK
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
