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View Structure Prediction Details

Protein: ACC1
Organism: Saccharomyces cerevisiae
Length: 2233 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ACC1.

Description E-value Query
Range
Subject
Range
gi|14423245 - gi|14423245|gb|AAK62312.1|AF359516_1 acetyl-CoA carboxylase [Lolium rigidum]
0.0 [738..1808] [1..1071]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [926..2198] [867..2080]
gi|14423249 - gi|14423249|gb|AAK62314.1|AF359518_1 acetyl-CoA carboxylase [Zea mays]
0.0 [738..1808] [1..1078]
ACAC_CHICK - Acetyl-CoA carboxylase OS=Gallus gallus GN=ACAC PE=1 SV=1
0.0 [39..2232] [98..2315]
ACACA_RAT - Acetyl-CoA carboxylase 1 OS=Rattus norvegicus GN=Acaca PE=1 SV=1
0.0 [36..2232] [94..2337]
gi|11992991 - gi|11992991|gb|AAF04493.2|AF157612_1 acetyl-CoA carboxylase 1 precursor [Toxoplasma gondii]
0.0 [19..1478] [301..1712]
gi|171504 - gi|171504|gb|AAA20073.1| acetyl-CoA carboxylase [Saccharomyces cerevisiae]
0.0 [1..2233] [1..2237]

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Predicted Domain #1
Region A:
Residues: [1-174]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSEESLFESS PQKMEYEITN YSERHTELPG HFIGLNTVDK LEESPLRDFV KSHGGHTVIS  60
   61 KILIANNGIA AVKEIRSVRK WAYETFGDDR TVQFVAMATP EDLEANAEYI RMADQYIEVP 120
  121 GGTNNNNYAN VDLIVDIAER ADVDAVWAGW GHASENPLLP EKLSQSKRKV IFIG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 700.228787
Match: 1bncA_
Description: Biotin carboxylase subunit of acetyl-CoA carboxylase (BC), C-domain; Biotin carboxylase subunit of acetyl-CoA carboxylase, (BC), N-domain; Biotin carboxylase subunit of acetyl-CoA carboxylase (BC), domain 2
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
acetyl-CoA carboxylase activity 7.97944928068929 bayes_pls_golite062009
CoA carboxylase activity 7.26031530137805 bayes_pls_golite062009
ligase activity, forming carbon-carbon bonds 7.11064677387039 bayes_pls_golite062009
biotin carboxylase activity 6.9547407447638 bayes_pls_golite062009
ligase activity 6.37416374794432 bayes_pls_golite062009
carbamoyl-phosphate synthase activity 4.25267317906061 bayes_pls_golite062009
carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity 4.17451795830682 bayes_pls_golite062009
succinate-CoA ligase activity 3.60521632399322 bayes_pls_golite062009
CoA-ligase activity 3.23896308753196 bayes_pls_golite062009
acid-thiol ligase activity 3.04454283840859 bayes_pls_golite062009
methylcrotonoyl-CoA carboxylase activity 2.98357921316004 bayes_pls_golite062009
glutathione synthase activity 2.75320638765219 bayes_pls_golite062009
ligase activity, forming carbon-sulfur bonds 2.73831154716701 bayes_pls_golite062009
ligase activity, forming carbon-nitrogen bonds 1.74185999556024 bayes_pls_golite062009
glutathione binding 1.60917807172757 bayes_pls_golite062009
phosphoribosylaminoimidazole carboxylase activity 1.57708889650281 bayes_pls_golite062009
succinate-CoA ligase (ADP-forming) activity 1.55053478055591 bayes_pls_golite062009
binding 1.51238789441513 bayes_pls_golite062009
acid-amino acid ligase activity 1.40905042897991 bayes_pls_golite062009
transporter activity 1.29381792295125 bayes_pls_golite062009
carbon-nitrogen ligase activity, with glutamine as amido-N-donor 1.11645327303429 bayes_pls_golite062009
catalytic activity 1.08688404807699 bayes_pls_golite062009
phosphoribosylamine-glycine ligase activity 1.04915286326924 bayes_pls_golite062009
propionyl-CoA carboxylase activity 0.643677287269589 bayes_pls_golite062009
hydrolase activity 0.543813086594651 bayes_pls_golite062009
protein binding 0.455938814211606 bayes_pls_golite062009
succinate-CoA ligase (GDP-forming) activity 0.34559667514727 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [175-201]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PPGNAMRSLG DKISSTIVAQ SAKVPCI

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [293-318]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AGRARHLEVQ LLADQYGTNI SLFGRD

[Run NCBI BLAST on this sequence.]

Region C:
Residues: [332-452]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 APVTIAKAET FHEMEKAAVR LGKLVGYVSA GTVEYLYSHD DGKFYFLELN PRLQVEHPTT  60
   61 EMVSGVNLPA AQLQIAMGIP MHRISDIRTL YGMNPHSASE IDFEFKTQDA TKKQRRPIPK 120
  121 G

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 700.228787
Match: 1bncA_
Description: Biotin carboxylase subunit of acetyl-CoA carboxylase (BC), C-domain; Biotin carboxylase subunit of acetyl-CoA carboxylase, (BC), N-domain; Biotin carboxylase subunit of acetyl-CoA carboxylase (BC), domain 2
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [202-292]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PWSGTGVDTV HVDEKTGLVS VDDDIYQKGC CTSPEDGLQK AKRIGFPVMI KASEGGGGKG  60
   61 IRQVEREEDF IALYHQAANE IPGSPIFIMK L

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [319-331]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 CSVQRRHQKI IEE

[Run NCBI BLAST on this sequence.]

Region C:
Residues: [453-603]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HCTACRITSE DPNDGFKPSG GTLHELNFRS SSNVWGYFSV GNNGNIHSFS DSQFGHIFAF  60
   61 GENRQASRKH MVVALKELSI RGDFRTTVEY LIKLLETEDF EDNTITTGWL DDLITHKMTA 120
  121 EKPDPTLAVI CGAATKAFLA SEEARHKYIE S

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 700.228787
Match: 1bncA_
Description: Biotin carboxylase subunit of acetyl-CoA carboxylase (BC), C-domain; Biotin carboxylase subunit of acetyl-CoA carboxylase, (BC), N-domain; Biotin carboxylase subunit of acetyl-CoA carboxylase (BC), domain 2
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [604-695]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LQKGQVLSKD LLQTMFPVDF IHEGKRYKFT VAKSGNDRYT LFINGSKCDI ILRQLSDGGL  60
   61 LIAIGGKSHT IYWKEEVAAT RLSVDSMTTL LE

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.930 b.60.1 Lipocalins
View Download 0.898 d.15.5 Staphylokinase/streptokinase
View Download 0.931 b.101.1 Ribonuclease domain of colicin E3
View Download 0.959 b.61.2 Metalloprotease inhibitor
View Download 0.909 b.61.4 Quinohemoprotein amine dehydrogenase A chain, domain 3
View Download 0.884 b.61.2 Metalloprotease inhibitor
View Download 0.869 b.55.1 PH domain-like
View Download 0.865 b.60.1 Lipocalins
View Download 0.859 b.61.3 D-aminopeptidase, middle and C-terminal domains
View Download 0.845 d.15.1 Ubiquitin-like
View Download 0.835 b.1.1 Immunoglobulin
View Download 0.823 b.61.4 Quinohemoprotein amine dehydrogenase A chain, domain 3
View Download 0.794 b.55.1 PH domain-like
View Download 0.770 b.55.1 PH domain-like
View Download 0.766 d.233.1 Inhibitor of vertebrate lysozyme, Ivy
View Download 0.754 b.63.1 Oncogene products
View Download 0.749 d.93.1 SH2 domain
View Download 0.742 b.1.1 Immunoglobulin
View Download 0.739 b.60.1 Lipocalins
View Download 0.718 d.15.2 CAD & PB1 domains
View Download 0.717 d.82.2 Frataxin-like
View Download 0.702 d.82.2 Frataxin-like
View Download 0.699 d.93.1 SH2 domain
View Download 0.692 b.55.1 PH domain-like
View Download 0.687 b.55.1 PH domain-like
View Download 0.687 b.63.1 Oncogene products
View Download 0.685 d.93.1 SH2 domain
View Download 0.672 d.93.1 SH2 domain
View Download 0.664 b.1.1 Immunoglobulin
View Download 0.654 d.150.1 4'-phosphopantetheinyl transferase
View Download 0.639 b.60.1 Lipocalins
View Download 0.634 b.49.1 N-terminal domain of alpha and beta subunits of F1 ATP synthase
View Download 0.617 d.93.1 SH2 domain
View Download 0.614 b.1.1 Immunoglobulin
View Download 0.613 g.41.3 Zinc beta-ribbon
View Download 0.607 b.61.1 Avidin/streptavidin
View Download 0.590 b.1.1 Immunoglobulin
View Download 0.555 b.1.1 Immunoglobulin
View Download 0.554 d.110.1 Profilin (actin-binding protein)
View Download 0.551 c.55.5 MTH1175-like
View Download 0.545 b.114.1 N-utilization substance G protein NusG, insert domain
View Download 0.543 g.41.3 Zinc beta-ribbon
View Download 0.538 b.1.1 Immunoglobulin
View Download 0.531 d.50.1 dsRNA-binding domain-like
View Download 0.530 b.118.1 FAS1 domain
View Download 0.526 b.1.1 Immunoglobulin
View Download 0.517 d.150.1 4'-phosphopantetheinyl transferase
View Download 0.514 b.61.5 Dipeptidyl peptidase I (cathepsin C), exclusion domain
View Download 0.511 b.92.1 Composite domain of metallo-dependent hydrolases
View Download 0.499 d.50.3 PI-Pfui intein middle domain
View Download 0.498 b.60.1 Lipocalins
View Download 0.483 b.40.4 Nucleic acid-binding proteins
View Download 0.474 b.1.18 E set domains
View Download 0.464 b.7.2 Periplasmic chaperone C-domain
View Download 0.462 b.1.1 Immunoglobulin
View Download 0.458 b.118.1 FAS1 domain
View Download 0.454 b.1.1 Immunoglobulin
View Download 0.447 b.1.1 Immunoglobulin
View Download 0.439 d.105.1 Clathrin adaptor appendage, alpha and beta chain-specific domain
View Download 0.433 b.40.4 Nucleic acid-binding proteins
View Download 0.427 b.115.1 Fucose-binding lectin II (PA-IIL)
View Download 0.423 d.204.1 Ribosome binding protein Y (YfiA homologue)
View Download 0.408 d.58.20 NAD-binding domain of HMG-CoA reductase
View Download 0.406 c.51.3 B12-dependend dehydatases associated subunit
View Download 0.403 b.23.1 Spermadhesin, CUB domain
View Download 0.401 b.60.1 Lipocalins
View Download 0.394 b.49.1 N-terminal domain of alpha and beta subunits of F1 ATP synthase
View Download 0.391 b.40.4 Nucleic acid-binding proteins
View Download 0.391 b.42.5 Actin-crosslinking proteins
View Download 0.388 d.110.1 Profilin (actin-binding protein)
View Download 0.376 b.113.1 N-terminal domain of MutM-like DNA repair proteins
View Download 0.374 b.60.1 Lipocalins
View Download 0.373 b.55.1 PH domain-like
View Download 0.369 b.40.4 Nucleic acid-binding proteins
View Download 0.363 d.15.6 Superantigen toxins, C-terminal domain
View Download 0.352 b.50.1 Acid proteases
View Download 0.341 b.60.1 Lipocalins
View Download 0.334 b.38.1 Sm-like ribonucleoproteins
View Download 0.309 d.15.7 Immunoglobulin-binding domains
View Download 0.306 d.15.1 Ubiquitin-like
View Download 0.304 c.55.6 DNA repair protein MutS, domain II
View Download 0.302 d.106.1 Sterol carrier protein, SCP
View Download 0.301 c.97.1 Cytidine deaminase-like
View Download 0.300 c.30.1 PreATP-grasp domain
View Download 0.287 f.4.1 OMPA-like
View Download 0.279 b.60.1 Lipocalins
View Download 0.277 b.54.1 Core binding factor beta, CBF
View Download 0.268 b.42.2 Ricin B-like lectins
View Download 0.264 b.71.1 Glycosyl hydrolase domain
View Download 0.262 b.76.2 Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain
View Download 0.255 b.60.1 Lipocalins
View Download 0.249 d.21.1 Diaminopimelate epimerase-like
View Download 0.248 d.21.1 Diaminopimelate epimerase-like
View Download 0.241 b.42.2 Ricin B-like lectins
View Download 0.237 b.60.1 Lipocalins
View Download 0.228 b.125.1 Lipoprotein localization factors LolAB
View Download 0.227 b.29.1 Concanavalin A-like lectins/glucanases
View Download 0.226 b.42.6 IP3 receptor type 1 binding core, domain 1

Predicted Domain #5
Region A:
Residues: [696-781]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VENDPTQLRT PSPGKLVKFL VENGEHIIKG QPYAEIEVMK MQMPLVSQEN GIVQLLKQPG  60
   61 STIVAGDIMA IMTLDDPSKV KHALPF

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 12.522879
Match: 1dczA_
Description: Biotin carboxyl carrier domain of transcarboxylase (TC 1.3S)
Matching Structure (courtesy of the PDB):

Predicted Domain #6
Region A:
Residues: [782-989]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EGMLPDFGSP VIEGTKPAYK FKSLVSTLEN ILKGYDNQVI MNASLQQLIE VLRNPKLPYS  60
   61 EWKLHISALH SRLPAKLDEQ MEELVARSLR RGAVFPARQL SKLIDMAVKN PEYNPDKLLG 120
  121 AVVEPLADIA HKYSNGLEAH EHSIFVHFLE EYYEVEKLFN GPNVREENII LKLRDENPKD 180
  181 LDKVALTVLS HSKVSAKNNL ILAILKHY

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #7
Region A:
Residues: [990-1091]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QPLCKLSSKV SAIFSTPLQH IVELESKATA KVALQAREIL IQGALPSVKE RTEQIEHILK  60
   61 SSVVKVAYGS SNPKRSEPDL NILKDLIDSN YVVFDVLLQF LT

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.543 0.090 biotin carboxylase activity a.52.1 Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
View Download 0.867 0.072 biotin carboxylase activity a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.615 0.043 biotin carboxylase activity a.24.9 alpha-catenin/vinculin
View Download 0.671 0.019 biotin carboxylase activity a.24.17 Group V grass pollen allergen
View Download 0.497 N/A N/A a.51.1 Cytochrome c oxidase subunit h
View Download 0.495 N/A N/A a.24.7 FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)
View Download 0.494 N/A N/A a.24.4 Hemerythrin
View Download 0.453 N/A N/A a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.452 N/A N/A d.45.1 ClpS-like
View Download 0.410 N/A N/A a.7.2 Enzyme IIa from lactose specific PTS, IIa-lac
View Download 0.370 N/A N/A a.4.5 "Winged helix" DNA-binding domain
View Download 0.361 N/A N/A a.60.6 DNA polymerase beta, N-terminal domain-like
View Download 0.356 N/A N/A d.26.1 FKBP-like
View Download 0.352 N/A N/A a.24.16 Nucleotidyltransferase substrate binding subunit/domain
View Download 0.335 N/A N/A a.71.1 Endoplasmic reticulum protein ERP29, C-domain
View Download 0.317 N/A N/A a.7.7 BAG domain
View Download 0.315 N/A N/A a.91.1 Regulator of G-protein signalling, RGS
View Download 0.312 N/A N/A a.7.8 GAT domain
View Download 0.306 N/A N/A a.126.1 Serum albumin-like
View Download 0.305 N/A N/A a.4.5 "Winged helix" DNA-binding domain
View Download 0.297 N/A N/A a.3.1 Cytochrome c
View Download 0.289 N/A N/A a.52.1 Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
View Download 0.287 N/A N/A a.74.1 Cyclin-like
View Download 0.280 N/A N/A a.3.1 Cytochrome c
View Download 0.273 N/A N/A a.4.5 "Winged helix" DNA-binding domain
View Download 0.271 N/A N/A a.4.1 Homeodomain-like
View Download 0.260 N/A N/A f.15.1 Small-conductance potassium channel
View Download 0.257 N/A N/A a.25.2 Thermoplasma ferritin-like 4-helical bundle
View Download 0.255 N/A N/A a.70.1 N-terminal domain of the delta subunit of the F1F0-ATP synthase
View Download 0.254 N/A N/A a.24.10 Histidine-containing phosphotransfer domain, HPT domain
View Download 0.248 N/A N/A a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.248 N/A N/A a.7.7 BAG domain
View Download 0.247 N/A N/A a.83.1 Guanido kinase N-terminal domain
View Download 0.246 N/A N/A a.1.1 Globin-like
View Download 0.245 N/A N/A d.58.44 Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
View Download 0.241 N/A N/A a.4.5 "Winged helix" DNA-binding domain
View Download 0.241 N/A N/A a.24.16 Nucleotidyltransferase substrate binding subunit/domain
View Download 0.240 N/A N/A d.58.26 GHMP Kinase, C-terminal domain
View Download 0.238 N/A N/A a.74.1 Cyclin-like
View Download 0.237 N/A N/A a.158.1 F-box domain
View Download 0.235 N/A N/A a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.233 N/A N/A a.181.1 Antibiotic binding domain of TipA-like multidrug resistance regulators
View Download 0.232 N/A N/A d.39.1 Dynein light chain 8 (DLC8)
View Download 0.230 N/A N/A a.71.2 Helical domain of Sec23/24
View Download 0.228 N/A N/A a.77.1 DEATH domain
View Download 0.227 N/A N/A d.80.1 Tautomerase/MIF
View Download 0.226 N/A N/A a.23.4 Mitochondrial import receptor subunit Tom20
View Download 0.223 N/A N/A a.2.3 Chaperone J-domain
View Download 0.218 N/A N/A a.47.2 t-snare proteins
View Download 0.218 N/A N/A a.134.1 Fungal elicitin
View Download 0.212 N/A N/A a.74.1 Cyclin-like
View Download 0.211 N/A N/A a.135.1 Tetraspanin
View Download 0.208 N/A N/A d.16.1 FAD-linked reductases, C-terminal domain
View Download 0.208 N/A N/A d.58.26 GHMP Kinase, C-terminal domain

Predicted Domain #8
Region A:
Residues: [1092-1154]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HQDPVVTAAA AQVYIRRAYR AYTIGDIRVH EGVTVPIVEW KFQLPSAAFS TFPTVKSKMG  60
   61 MNR

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.536 d.17.1 Cystatin/monellin
View Download 0.456 b.34.4 Electron transport accessory proteins
View Download 0.483 d.58.18 Regulatory domain in the aminoacid metabolism
View Download 0.526 d.71.1 Cell division protein MinE topological specificity domain
View Download 0.689 d.81.1 Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain
View Download 0.450 d.51.1 Eukaryotic type KH-domain (KH-domain type I)
View Download 0.428 d.50.1 dsRNA-binding domain-like
View Download 0.426 d.17.1 Cystatin/monellin
View Download 0.410 d.58.5 GlnB-like
View Download 0.383 d.58.23 Probable ACP-binding domain of malonyl-CoA ACP transacylase
View Download 0.368 b.4.1 HSP40/DnaJ peptide-binding domain
View Download 0.357 d.94.1 HPr-like
View Download 0.355 d.52.7 Ribosome-binding factor A, RbfA
View Download 0.350 d.94.1 HPr-like
View Download 0.343 c.47.1 Thioredoxin-like
View Download 0.339 d.50.1 dsRNA-binding domain-like
View Download 0.336 d.51.1 Eukaryotic type KH-domain (KH-domain type I)
View Download 0.325 d.230.2 Flavin-binding protein dodecin
View Download 0.322 d.74.3 RBP11-like subunits of RNA polymerase
View Download 0.313 d.58.17 Metal-binding domain
View Download 0.308 d.17.2 Copper amine oxidase, domains 1 and 2
View Download 0.306 b.34.5 Translation proteins SH3-like domain
View Download 0.305 d.58.40 D-ribose-5-phosphate isomerase (RpiA), lid domain
View Download 0.299 a.60.1 SAM/Pointed domain
View Download 0.294 d.17.2 Copper amine oxidase, domains 1 and 2
View Download 0.289 d.49.1 Signal recognition particle alu RNA binding heterodimer, SRP9/14
View Download 0.276 d.58.7 RNA-binding domain, RBD
View Download 0.267 d.121.1 DNA topoisomerase I domain
View Download 0.266 d.52.5 Probable GTPase Der, C-terminal domain
View Download 0.255 d.51.1 Eukaryotic type KH-domain (KH-domain type I)
View Download 0.255 d.58.12 eEF-1beta-like
View Download 0.255 d.58.8 Viral DNA-binding domain
View Download 0.253 a.60.2 RuvA domain 2-like
View Download 0.250 a.60.11 Hypothetical protein YjbJ
View Download 0.249 c.47.1 Thioredoxin-like
View Download 0.248 d.201.1 SRP19
View Download 0.242 d.89.1 Origin of replication-binding domain, RBD-like
View Download 0.241 d.52.3 Prokaryotic type KH domain (KH-domain type II)
View Download 0.232 c.47.1 Thioredoxin-like
View Download 0.228 d.58.17 Metal-binding domain
View Download 0.225 b.1.1 Immunoglobulin
View Download 0.222 d.58.17 Metal-binding domain
View Download 0.213 d.58.7 RNA-binding domain, RBD
View Download 0.208 d.58.5 GlnB-like
View Download 0.208 a.60.1 SAM/Pointed domain
View Download 0.204 d.50.2 Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain
View Download 0.203 c.47.1 Thioredoxin-like
View Download 0.202 d.58.13 Anticodon-binding domain of PheRS
View Download 0.202 b.38.1 Sm-like ribonucleoproteins
View Download 0.202 d.58.5 GlnB-like

Predicted Domain #9
Region A:
Residues: [1155-1328]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AVSVSDLSYV ANSQSSPLRE GILMAVDHLD DVDEILSQSL EVIPRHQSSS NGPAPDRSGS  60
   61 SASLSNVANV CVASTEGFES EEEILVRLRE ILDLNKQELI NASIRRITFM FGFKDGSYPK 120
  121 YYTFNGPNYN ENETIRHIEP ALAFQLELGR LSNFNIKPIF TDNRNIHVYE AVSK

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #10
Region A:
Residues: [1329-1527]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TSPLDKRFFT RGIIRTGHIR DDISIQEYLT SEANRLMSDI LDNLEVTDTS NSDLNHIFIN  60
   61 FIAVFDISPE DVEAAFGGFL ERFGKRLLRL RVSSAEIRII IKDPQTGAPV PLRALINNVS 120
  121 GYVIKTEMYT EVKNAKGEWV FKSLGKPGSM HLRPIATPYP VKEWLQPKRY KAHLMGTTYV 180
  181 YDFPELFRQA SSSQWKNFS

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #11
Region A:
Residues: [1528-2146]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ADVKLTDDFF ISNELIEDEN GELTEVEREP GANAIGMVAF KITVKTPEYP RGRQFVVVAN  60
   61 DITFKIGSFG PQEDEFFNKV TEYARKRGIP RIYLAANSGA RIGMAEEIVP LFQVAWNDAA 120
  121 NPDKGFQYLY LTSEGMETLK KFDKENSVLT ERTVINGEER FVIKTIIGSE DGLGVECLRG 180
  181 SGLIAGATSR AYHDIFTITL VTCRSVGIGA YLVRLGQRAI QVEGQPIILT GAPAINKMLG 240
  241 REVYTSNLQL GGTQIMYNNG VSHLTAVDDL AGVEKIVEWM SYVPAKRNMP VPILETKDTW 300
  301 DRPVDFTPTN DETYDVRWMI EGRETESGFE YGLFDKGSFF ETLSGWAKGV VVGRARLGGI 360
  361 PLGVIGVETR TVENLIPADP ANPNSAETLI QEPGQVWHPN SAFKTAQAIN DFNNGEQLPM 420
  421 MILANWRGFS GGQRDMFNEV LKYGSFIVDA LVDYKQPIII YIPPTGELRG GSWVVVDPTI 480
  481 NADQMEMYAD VNARAGVLEP QGMVGIKFRR EKLLDTMNRL DDKYRELRSQ LSNKSLAPEV 540
  541 HQQISKQLAD RERELLPIYG QISLQFADLH DRSSRMVAKG VISKELEWTE ARRFFFWRLR 600
  601 RRLNEEYLIK RLSHQVGEA

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #12
Region A:
Residues: [2147-2233]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SRLEKIARIR SWYPASVDHE DDRQVATWIE ENYKTLDDKL KGLKLESFAQ DLAKKIRSDH  60
   61 DNAIDGLSEV IKMLSTDDKE KLLKTLK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.418 a.28.1 ACP-like
View Download 0.492 a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.509 a.46.1 Methionine synthase domain
View Download 0.466 f.34.1 Mechanosensitive channel protein MscS (YggB), transmembrane region
View Download 0.394 a.23.1 HSC20 (HSCB), C-terminal oligomerisation domain
View Download 0.358 c.9.1 Barstar (barnase inhibitor)
View Download 0.342 a.85.1 Hemocyanin, N-terminal domain
View Download 0.334 a.64.1 Saposin
View Download 0.307 a.74.1 Cyclin-like
View Download 0.289 a.51.1 Cytochrome c oxidase subunit h
View Download 0.271 a.7.8 GAT domain
View Download 0.265 a.4.3 ARID-like
View Download 0.261 a.105.1 FIS-like
View Download 0.260 a.7.1 Spectrin repeat
View Download 0.256 a.118.1 ARM repeat
View Download 0.245 a.47.2 t-snare proteins
View Download 0.244 a.2.3 Chaperone J-domain
View Download 0.242 a.7.1 Spectrin repeat
View Download 0.242 a.77.1 DEATH domain
View Download 0.241 a.25.1 Ferritin-like
View Download 0.240 a.8.1 Bacterial immunoglobulin/albumin-binding domains
View Download 0.238 c.51.1 Anticodon-binding domain of Class II aaRS
View Download 0.234 c.47.1 Thioredoxin-like
View Download 0.233 a.126.1 Serum albumin-like
View Download 0.227 a.105.1 FIS-like
View Download 0.226 a.24.16 Nucleotidyltransferase substrate binding subunit/domain
View Download 0.223 a.58.1 Chemotaxis receptor methyltransferase CheR, N-terminal domain
View Download 0.222 a.4.5 "Winged helix" DNA-binding domain
View Download 0.220 a.7.1 Spectrin repeat
View Download 0.219 a.80.1 DNA polymerase III clamp loader subunits, C-terminal domain
View Download 0.215 d.95.2 Homing endonucleases
View Download 0.215 a.22.1 Histone-fold
View Download 0.204 a.76.1 Iron-dependent represor protein, dimerization domain
View Download 0.203 a.4.3 ARID-like
View Download 0.201 a.60.2 RuvA domain 2-like


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle