| Protein: | SIW14 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 281 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SIW14.
| Description | E-value | Query Range |
Subject Range |
|
|
2.0E-91 | [1..281] | [1..281] |
|
|
5.0E-41 | [117..271] | [30..183] |
|
|
9.0E-39 | [109..279] | [4..173] |
|
|
3.0E-33 | [67..263] | [145..325] |
|
Region A: Residues: [1-84] |
1 11 21 31 41 51
| | | | | |
1 MGLYQAKNDE GSDPKSSSKI DDLIENEAEI IRLIKEDGKL LIDNGDGRDI HNIIQEDKLL 60
61 SVEFNEVLKR FHGEEKSDIP RKEF
|
| Detection Method: |  |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [85-179] |
1 11 21 31 41 51
| | | | | |
1 DEDEDDGYDS NEHHQKTIEV MNTLNHVINK EVIPPENFSH VVGEIYRSSF PRQENFSFLH 60
61 ERLKLKSILV LIPEEYPQEN LNFLKLTGIK LYQVG
|
|
Region B: Residues: [197-218] |
1 11 21 31 41 51
| | | | | |
1 KALEIVLNPA NQPILIHCNR GK
|
| Detection Method: | |
| Confidence: | 31.69897 |
| Match: | 1d5rA_ |
| Description: | Pten tumor suppressor (Phoshphoinositide phosphatase), C-terminal domain; Phoshphoinositide phosphatase Pten (Pten tumor suppressor), N-terminal domain |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| phosphoprotein phosphatase activity | 7.30669036331612 | bayes_pls_golite062009 |
| phosphatase activity | 6.6585143972081 | bayes_pls_golite062009 |
| phosphoric ester hydrolase activity | 6.44546424348532 | bayes_pls_golite062009 |
| hydrolase activity, acting on ester bonds | 5.56007278295923 | bayes_pls_golite062009 |
| protein tyrosine phosphatase activity | 5.3097342170423 | bayes_pls_golite062009 |
| transmembrane receptor protein phosphatase activity | 2.94635032478625 | bayes_pls_golite062009 |
| transmembrane receptor protein tyrosine phosphatase activity | 2.94635032478625 | bayes_pls_golite062009 |
| protein tyrosine/serine/threonine phosphatase activity | 2.77531895423367 | bayes_pls_golite062009 |
| protein serine/threonine phosphatase activity | 1.95004535887255 | bayes_pls_golite062009 |
| hydrolase activity | 1.5596484415033 | bayes_pls_golite062009 |
| protein binding | 1.28180613509993 | bayes_pls_golite062009 |
| binding | 1.27238793273026 | bayes_pls_golite062009 |
| inositol or phosphatidylinositol phosphatase activity | 1.1200449509328 | bayes_pls_golite062009 |
| catalytic activity | 1.06283028154109 | bayes_pls_golite062009 |
| lipid phosphatase activity | 1.05085928819585 | bayes_pls_golite062009 |
| non-membrane spanning protein tyrosine phosphatase activity | 0.724257798127697 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 0.541577955624444 | bayes_pls_golite062009 |
| actin binding | 0.174917691236515 | bayes_pls_golite062009 |
| phosphotransferase activity, alcohol group as acceptor | 0.0776644624761281 | bayes_pls_golite062009 |
| kinase activity | 0.0715870881653981 | bayes_pls_golite062009 |
|
Region A: Residues: [180-196] |
1 11 21 31 41 51
| | | | | |
1 MSGNKEPFVN IPSHLLT
|
|
Region B: Residues: [219-281] |
1 11 21 31 41 51
| | | | | |
1 HRTGCLIGCI RKLQNWSLTM IFDEYRRFAF PKARALDQQF IEMYDDDEIK RIASKNNWLP 60
61 LQW
|
| Detection Method: | |
| Confidence: | 31.69897 |
| Match: | 1d5rA_ |
| Description: | Pten tumor suppressor (Phoshphoinositide phosphatase), C-terminal domain; Phoshphoinositide phosphatase Pten (Pten tumor suppressor), N-terminal domain |
| Matching Structure (courtesy of the PDB): |
|
