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Protein Overview: SIW14_YEAST

General Information:
Name(s) found: SIW14_YEAST [Swiss-Prot]
Description(s) found:
  • Tyrosine-protein phosphatase SIW14 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SIW14 PE=1 SV=1 [Swiss-Prot]
    • Organism: Saccharomyces cerevisiae S288c
    Length: 281 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGLYQAKNDE GSDPKSSSKI DDLIENEAEI IRLIKEDGKL LIDNGDGRDI HNIIQEDKLL  60
   61 SVEFNEVLKR FHGEEKSDIP RKEFDEDEDD GYDSNEHHQK TIEVMNTLNH VINKEVIPPE 120
  121 NFSHVVGEIY RSSFPRQENF SFLHERLKLK SILVLIPEEY PQENLNFLKL TGIKLYQVGM 180
  181 SGNKEPFVNI PSHLLTKALE IVLNPANQPI LIHCNRGKHR TGCLIGCIRK LQNWSLTMIF 240
  241 DEYRRFAFPK ARALDQQFIE MYDDDEIKRI ASKNNWLPLQ W

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..84] deduced N/A No confident structure predictions are available.
    2 View Details [85..179]
    [197..218]    		 PSI-BLAST 31.69897 Pten tumor suppressor (Phoshphoinositide phosphatase), C-terminal domain; Phoshphoinositide phosphatase Pten (Pten tumor suppressor), N-terminal domain
    3 View Details [180..196]
    [219..281]    		 PSI-BLAST 31.69897 Pten tumor suppressor (Phoshphoinositide phosphatase), C-terminal domain; Phoshphoinositide phosphatase Pten (Pten tumor suppressor), N-terminal domain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • phosphoprotein phosphatase activity
    		•  7.30669036331612 bayes_pls_golite062009
  • phosphatase activity
    		•  6.6585143972081 bayes_pls_golite062009
  • phosphoric ester hydrolase activity
    		•  6.44546424348532 bayes_pls_golite062009
  • hydrolase activity, acting on ester bonds
    		•  5.56007278295923 bayes_pls_golite062009
  • protein tyrosine phosphatase activity
    		•  5.3097342170423 bayes_pls_golite062009
  • transmembrane receptor protein phosphatase activity
    		•  2.94635032478625 bayes_pls_golite062009
  • transmembrane receptor protein tyrosine phosphatase activity
    		•  2.94635032478625 bayes_pls_golite062009
  • protein tyrosine/serine/threonine phosphatase activity
    		•  2.77531895423367 bayes_pls_golite062009
  • protein serine/threonine phosphatase activity
    		•  1.95004535887255 bayes_pls_golite062009
  • hydrolase activity
    		•  1.5596484415033 bayes_pls_golite062009
  • protein binding
    		•  1.28180613509993 bayes_pls_golite062009
  • binding
    		•  1.27238793273026 bayes_pls_golite062009
  • inositol or phosphatidylinositol phosphatase activity
    		•  1.1200449509328 bayes_pls_golite062009
  • catalytic activity
    		•  1.06283028154109 bayes_pls_golite062009
  • lipid phosphatase activity
    		•  1.05085928819585 bayes_pls_golite062009
  • non-membrane spanning protein tyrosine phosphatase activity
    		•  0.724257798127697 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  0.541577955624444 bayes_pls_golite062009
  • actin binding
    		•  0.174917691236515 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  0.0776644624761281 bayes_pls_golite062009
  • kinase activity
    		•  0.0715870881653981 bayes_pls_golite062009
    3 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle