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View Structure Prediction Details

Protein: TRI1
Organism: Saccharomyces cerevisiae
Length: 226 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TRI1.

Description E-value Query
Range
Subject
Range
gi|207342139 - gi|207342139|gb|EDZ69997.1| YMR233Wp-like protein [Saccharomyces cerevisiae AWRI1631]
gi|151945938 - gi|151945938|gb|EDN64170.1| conserved protein [Saccharomyces cerevisiae YJM789]
gi|190408460 - gi|190408460|gb|EDV11725.1| hypothetical protein SCRG_02128 [Saccharomyces cerevisiae RM11-1a]
TRI1 - Non-essential sumoylated protein of unknown function with similarity to components of human SWI/SNF ...
TRI1_YEAST - Protein TRI1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=TRI1 PE=1 SV=1
6.0E-57 [1..226] [1..226]
SMRD1_MOUSE, SCD... - SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1 OS=Mus...
1.0E-53 [47..222] [206..398]
gi|114644841, gi... - gi|114644841|ref|XP_001155587.1| PREDICTED: SWI/SNF-related matrix-associated actin-dependent regula...
gi|4566530 - gi|4566530|gb|AAD23390.1|AF109733_1 SWI/SNF-related, matrix-associated, actin-dependent regulator of...
gi|109096590 - gi|109096590|ref|XP_001110916.1| PREDICTED: similar to SWI/SNF-related matrix-associated actin-depen...
tr|G3HX65|G3HX65... - SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1 OS=Cri...
3.0E-52 [47..222] [147..339]
gi|195566518, gi... - gi|195566518|ref|XP_002106827.1| GD15903 [Drosophila simulans], gi|194204219|gb|EDX17795.1| GD15903 ...
Bap60-PA - The gene Brahma associated protein 60kD is referred to in FlyBase by the symbol Dmel\Bap60 (CG4303, ...
2.0E-50 [41..223] [201..402]
SMRD2_RAT - SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2 OS=Rat...
1.0E-48 [50..222] [230..417]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
1.0E-48 [50..222] [230..417]
gi|25405318, gi|... - gi|5430749|gb|AAD43149.1|AC007504_4 Hypothetical Protein [Arabidopsis thaliana], pir||A96532 hypothe...
6.0E-48 [1..219] [1..202]

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Predicted Domain #1
Region A:
Residues: [1-84]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MADINKYIPM VDAILSVSNP DEISPKRVRK ALQILYSVNL DSQRKLINEL ILERFGDIQE  60
   61 NPRVLIPKND LISRDQELSL RLQK

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.719 0.528 nucleus a.4.1 Homeodomain-like
View Download 0.791 0.012 nucleolus a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.726 0.011 nucleolus a.64.1 Saposin
View Download 0.774 0.006 nucleolus a.60.9 lambda integrase-like, N-terminal domain
View Download 0.762 0.003 cytoplasm a.24.7 FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)
View Download 0.704 N/A N/A a.4.5 "Winged helix" DNA-binding domain
View Download 0.660 N/A N/A a.4.1 Homeodomain-like
View Download 0.649 N/A N/A a.64.1 Saposin
View Download 0.647 N/A N/A a.64.1 Saposin
View Download 0.637 N/A N/A f.1.4 Bcl-2 inhibitors of programmed cell death
View Download 0.616 N/A N/A a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.587 N/A N/A a.23.5 Hemolysin expression modulating protein HHA
View Download 0.564 N/A N/A a.4.5 "Winged helix" DNA-binding domain
View Download 0.562 N/A N/A a.29.4 RecG, N-terminal domain
View Download 0.561 N/A N/A a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.561 N/A N/A d.203.1 DsrC, the gamma subunit of dissimilatory sulfite reductase
View Download 0.556 N/A N/A a.118.11 Cytochrome c oxidase subunit E
View Download 0.542 N/A N/A a.46.1 Methionine synthase domain
View Download 0.537 N/A N/A a.4.9 Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3
View Download 0.536 N/A N/A a.4.5 "Winged helix" DNA-binding domain
View Download 0.533 N/A N/A a.4.5 "Winged helix" DNA-binding domain
View Download 0.532 N/A N/A a.7.6 Ribosomal protein S20
View Download 0.524 N/A N/A a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.495 N/A N/A a.52.1 Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
View Download 0.495 N/A N/A a.80.1 DNA polymerase III clamp loader subunits, C-terminal domain
View Download 0.494 N/A N/A f.34.1 Mechanosensitive channel protein MscS (YggB), transmembrane region
View Download 0.487 N/A N/A a.46.2 Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain
View Download 0.482 N/A N/A a.5.4 Elongation factor TFIIS domain 2
View Download 0.479 N/A N/A a.24.3 Cytochromes
View Download 0.473 N/A N/A a.64.1 Saposin
View Download 0.471 N/A N/A a.48.3 Conserved domain common to transcription factors TFIIS, elongin A, CRSP70
View Download 0.467 N/A N/A a.61.1 Retroviral matrix proteins
View Download 0.455 N/A N/A a.118.1 ARM repeat
View Download 0.450 N/A N/A a.126.1 Serum albumin-like
View Download 0.433 N/A N/A a.24.17 Group V grass pollen allergen
View Download 0.432 N/A N/A a.4.1 Homeodomain-like
View Download 0.428 N/A N/A a.118.1 ARM repeat
View Download 0.424 N/A N/A a.118.8 TPR-like
View Download 0.422 N/A N/A a.74.1 Cyclin-like
View Download 0.420 N/A N/A a.4.5 "Winged helix" DNA-binding domain
View Download 0.417 N/A N/A a.74.1 Cyclin-like
View Download 0.412 N/A N/A a.24.4 Hemerythrin
View Download 0.406 N/A N/A a.24.17 Group V grass pollen allergen
View Download 0.397 N/A N/A a.112.1 Description not found.
View Download 0.393 N/A N/A a.26.1 4-helical cytokines
View Download 0.387 N/A N/A a.101.1 Uteroglobin-like
View Download 0.383 N/A N/A a.118.9 ENTH/VHS domain
View Download 0.382 N/A N/A a.4.5 "Winged helix" DNA-binding domain
View Download 0.378 N/A N/A d.49.1 Signal recognition particle alu RNA binding heterodimer, SRP9/14
View Download 0.370 N/A N/A d.54.1 Enolase N-terminal domain-like
View Download 0.351 N/A N/A a.13.1 alpha-2-Macroglobulin receptor associated protein (RAP) domain 1
View Download 0.345 N/A N/A a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.342 N/A N/A a.118.9 ENTH/VHS domain
View Download 0.341 N/A N/A a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.339 N/A N/A a.74.1 Cyclin-like
View Download 0.333 N/A N/A a.65.1 Annexin
View Download 0.332 N/A N/A a.52.1 Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
View Download 0.332 N/A N/A d.102.1 Regulatory factor Nef
View Download 0.329 N/A N/A a.4.5 "Winged helix" DNA-binding domain
View Download 0.323 N/A N/A a.57.1 Protein HNS-dependent expression A; HdeA
View Download 0.318 N/A N/A a.159.2 FF domain
View Download 0.316 N/A N/A a.140.2 SAP domain
View Download 0.315 N/A N/A a.4.5 "Winged helix" DNA-binding domain
View Download 0.308 N/A N/A a.39.1 EF-hand
View Download 0.307 N/A N/A a.38.1 Helix-loop-helix DNA-binding domain
View Download 0.295 N/A N/A a.83.1 Guanido kinase N-terminal domain
View Download 0.290 N/A N/A a.71.1 Endoplasmic reticulum protein ERP29, C-domain
View Download 0.286 N/A N/A a.60.1 SAM/Pointed domain
View Download 0.274 N/A N/A d.45.1 ClpS-like
View Download 0.270 N/A N/A a.12.1 Kix domain of CBP (creb binding protein)
View Download 0.264 N/A N/A a.85.1 Hemocyanin, N-terminal domain
View Download 0.264 N/A N/A a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.261 N/A N/A a.40.1 Calponin-homology domain, CH-domain
View Download 0.260 N/A N/A a.80.1 DNA polymerase III clamp loader subunits, C-terminal domain
View Download 0.259 N/A N/A c.44.2 Enzyme IIB-cellobiose
View Download 0.259 N/A N/A a.121.1 Tetracyclin repressor-like, C-terminal domain
View Download 0.259 N/A N/A a.38.1 Helix-loop-helix DNA-binding domain
View Download 0.259 N/A N/A a.8.3 Families 57/38 glycoside transferase middle domain
View Download 0.259 N/A N/A a.2.8 Eukaryotic DNA topoisomerase I, dispensable insert domain
View Download 0.254 N/A N/A a.4.2 Methylated DNA-protein cysteine methyltransferase, C-terminal domain
View Download 0.254 N/A N/A a.28.3 Retrovirus capsid protein C-terminal domain
View Download 0.252 N/A N/A a.4.5 "Winged helix" DNA-binding domain
View Download 0.251 N/A N/A a.4.5 "Winged helix" DNA-binding domain
View Download 0.247 N/A N/A a.118.9 ENTH/VHS domain
View Download 0.246 N/A N/A a.77.1 DEATH domain
View Download 0.240 N/A N/A d.43.1 Elongation factor Ts (EF-Ts), dimerisation domain
View Download 0.237 N/A N/A d.56.1 GroEL-intermediate domain like
View Download 0.233 N/A N/A a.118.13 Arp2/3 complex 16 kDa subunit ARPC5
View Download 0.231 N/A N/A a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.229 N/A N/A a.2.3 Chaperone J-domain
View Download 0.229 N/A N/A a.2.4 Theta subunit of DNA polymerase III
View Download 0.227 N/A N/A a.77.1 DEATH domain
View Download 0.221 N/A N/A d.150.1 4'-phosphopantetheinyl transferase
View Download 0.219 N/A N/A a.71.2 Helical domain of Sec23/24
View Download 0.215 N/A N/A a.16.1 S15/NS1 RNA-binding domain
View Download 0.212 N/A N/A a.133.1 Phospholipase A2, PLA2
View Download 0.211 N/A N/A b.82.4 Regulatory protein AraC
View Download 0.209 N/A N/A a.162.1 Pre-protein croslinking domain of SecA
View Download 0.208 N/A N/A a.177.1 Sigma2 domain of RNA polymerase sigma factors
View Download 0.206 N/A N/A a.30.2 Homodimeric domain of signal transducing histidine kinase
View Download 0.202 N/A N/A a.3.1 Cytochrome c

Predicted functions:

Term Confidence Notes
binding 2.63842828741542 bayes_pls_golite062009
transcription regulator activity 2.62775554429027 bayes_pls_golite062009
RNA polymerase II transcription factor activity 0.953438255689584 bayes_pls_golite062009
histone binding 0.948950535074526 bayes_pls_golite062009
protein binding 0.529408559970229 bayes_pls_golite062009
specific RNA polymerase II transcription factor activity 0.439630834571696 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [85-226]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EEERPLRSTR KRKGKSESKS KRKKKKNDSP DSNSISVRKV LLSAPLQKFL GSEELPRTQV  60
   61 VKMIWQYIKE HDLQNPKDRR EILCDEKMEP IFGKKMTMFS MNKLLTKHLF NPDEIVKHEE 120
  121 EQKQTPEKEI KLENESLPNL SG

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 51.017729
Match: PF02201
Description: SWIB/MDM2 domain

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted functions:

Term Confidence Notes
transcription regulator activity 4.01592136607858 bayes_pls_golite062009
binding 3.20303599400601 bayes_pls_golite062009
basal transcription repressor activity 2.69162769894095 bayes_pls_golite062009
transcription coactivator activity 2.58234407051051 bayes_pls_golite062009
transcription repressor activity 1.98538788872171 bayes_pls_golite062009
transcription activator activity 1.83085389017135 bayes_pls_golite062009
transcription factor binding 1.73032563380905 bayes_pls_golite062009
transcription cofactor activity 1.60414428986898 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 1.51390743508971 bayes_pls_golite062009
protein binding 1.38134467541454 bayes_pls_golite062009
ligase activity 0.802664465339603 bayes_pls_golite062009
structural molecule activity 0.66106995897056 bayes_pls_golite062009
RNA polymerase II transcription factor activity 0.15313128037113 bayes_pls_golite062009
catalytic activity 0.121624777548864 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle