YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: RAD14
Organism: Saccharomyces cerevisiae
Length: 371 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RAD14.

Description E-value Query
Range		 Subject
Range
RAD14 - Protein that recognizes and binds damaged DNA during nucleotide excision repair; subunit of Nucleoti...
RAD14_YEAST - DNA repair protein RAD14 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=RAD14 PE=1 SV=2
gi|190408427 - gi|190408427|gb|EDV11692.1| DNA repair protein RAD14 [Saccharomyces cerevisiae RM11-1a]
 0.0 [1..371] [1..371]
RAD14_SCHPO - DNA repair protein rad14 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=rhp14 PE=1 SV=1
rhp14 - XP-A family homolog Rhp14
 1.0E-69 [90..371] [35..289]
gi|61357324, gi|... - gi|61357324|gb|AAX41371.1| xeroderma pigmentosum complementation group A [synthetic construct], gi|1...
XPA - xeroderma pigmentosum, complementation group A
 7.0E-65 [156..365] [72..267]
XPA_CHICK - DNA repair protein complementing XP-A cells homolog OS=Gallus gallus GN=XPA PE=2 SV=1
 7.0E-65 [150..365] [58..261]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
 9.0E-64 [156..365] [72..267]
XPA_MOUSE - DNA repair protein complementing XP-A cells homolog OS=Mus musculus GN=Xpa PE=1 SV=1
 7.0E-62 [153..365] [70..266]
XPA_XENLA - DNA repair protein complementing XP-A cells homolog OS=Xenopus laevis GN=xpa PE=2 SV=1
 6.0E-59 [156..365] [66..261]

Back

Predicted Domain #1
Region A:
Residues: [1-186] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTPEQKAKLE ANRKLAIERL RKRGILSSDQ LNRIESRNEP LKTRPLAVTS GSNRDDNAAA  60
   61 AVHVPNHNGQ PSALANTNTN TTSLYGSGVV DGSKRDASVL DKRPTDRIRP SIRKQDYIEY 120
  121 DFATMQNLNG GYINPKDKLP NSDFTDDQEF ESEFGSKKQK TLQDWKKEQL ERKMLYENAP 180
  181 PPEHIS

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 43.958607
Match: PF01286
Description: XPA protein N-terminal

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [187-371] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KAPKCIECHI NIEMDPVLHD VFKLQVCKQC SKEHPEKYAL LTKTECKEDY FLTDPELNDE  60
   61 DLFHRLEKPN PHSGTFARMQ LFVRCEVEAF AFKKWGGEEG LDEEWQRREE GKAHRREKKY 120
  121 EKKIKEMRLK TRAQEYTNRL REKKHGKAHI HHFSDPVDGG IDEDGYQIQR RRCTDCGLET 180
  181 EEIDI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 135.30103
Match: 1xpa__
Description: DNA repair factor XPA DNA- and RPA-binding domain, C-terminal subdomain; DNA repair factor XPA DNA- and RPA-binding domain, N-terminal subdomain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.81621967469952 bayes_pls_golite062009
transcription regulator activity 2.20400142735918 bayes_pls_golite062009
DNA binding 2.18702281581791 bayes_pls_golite062009
nucleic acid binding 2.04270847321412 bayes_pls_golite062009
protein binding 1.60194768638501 bayes_pls_golite062009
transcription factor activity 1.44182975349714 bayes_pls_golite062009
sequence-specific DNA binding 0.71242082351425 bayes_pls_golite062009
transcription activator activity 0.612819891085 bayes_pls_golite062009
structure-specific DNA binding 0.610805977602876 bayes_pls_golite062009
RNA polymerase II transcription factor activity 0.51536225088963 bayes_pls_golite062009
ligand-dependent nuclear receptor activity 0.44426709732278 bayes_pls_golite062009
transcription factor binding 0.40850395411512 bayes_pls_golite062009
double-stranded DNA binding 0.280685154942276 bayes_pls_golite062009
catalytic activity 0.101795606736461 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 0.0268930241866703 bayes_pls_golite062009
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle