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View Structure Prediction Details

Protein: ARG81
Organism: Saccharomyces cerevisiae
Length: 880 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ARG81.

Description E-value Query
Range
Subject
Range
ARGR2_YEAST - Arginine metabolism regulation protein II OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) G...
ARG81 - Zinc-finger transcription factor of the Zn(2)-Cys(6) binuclear cluster domain type, involved in the ...
0.0 [1..880] [1..880]
gi|2808662 - gi|2808662|emb|CAA11374.1| PrnA protein [Emericella nidulans]
1.0E-37 [2..192] [11..231]
gi|7688277 - gi|7688277|emb|CAB89829.1| PRO1 protein [Sordaria brevicollis]
1.0E-31 [2..149] [35..201]
PRIB_LENED - Protein priB OS=Lentinula edodes GN=priB PE=2 SV=1
2.0E-30 [11..214] [10..205]
gi|8218220 - gi|8218220|emb|CAB52588.2| PRO1 protein [Sordaria macrospora]
5.0E-30 [2..149] [35..200]
YCN3_SCHPO - Uncharacterized transcriptional regulatory protein C320.03 OS=Schizosaccharomyces pombe (strain 972 ...
SPCC320.03 - transcription factor
2.0E-29 [3..185] [58..239]
PRO1_NEUCR - Transcriptional regulatory protein pro-1 OS=Neurospora crassa GN=pro-1 PE=2 SV=1
PRO1_NEUCR - Transcriptional regulatory protein pro1 OS=Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 7...
7.0E-28 [2..149] [36..201]

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Predicted Domain #1
Region A:
Residues: [1-69]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGISSKNGPK KMGRAKTFTG CWTCRGRKVK CDLRHPHCQR CEKSNLPCGG YDIKLRWSKP  60
   61 MQFDPYGVP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 46.68867
Match: 1pyiA_
Description: PPR1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.91929847152301 bayes_pls_golite062009
transcription regulator activity 2.7831619208765 bayes_pls_golite062009
DNA binding 2.61829684541806 bayes_pls_golite062009
nucleic acid binding 2.43465257824542 bayes_pls_golite062009
transcription factor activity 1.55251487621784 bayes_pls_golite062009
sequence-specific DNA binding 0.87785810571597 bayes_pls_golite062009
RNA polymerase II transcription factor activity 0.83092951524649 bayes_pls_golite062009
specific RNA polymerase II transcription factor activity 0.79838087621523 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [70-880]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IPQNSPATTT NLSGSVDEPQ YQRRNIDFVR YDEEYVYHED MDDELTMLHT PPIEKISDNK  60
   61 TWIIKKFGVF KGTDKIDKQY APRKKRNRKR VAKSLESSAS ISLSSLPSSS TISFPIRHIE 120
  121 DKLRNKGHVK TGILSANDGV PPTPNLLDYD WNNLNITGYE WISSELRDDA LLSAVTLQGH 180
  181 HLGHTQPQEI SLEENSNVVS GEEHVNAKEH GCAFEADNQG SSTLPNKAAS ANDKLYQQNL 240
  241 KLLFQKNSSN SEEPDPQALI DDVFVNIEPR SLPASDLNKI TLAPPNEESR MPKSMLELTS 300
  301 YSSDLPPELV DIIPKTDLTV HGLARFLLNH YFNNVADKMT VVVLEKNPWK TLYFPRALMA 360
  361 LGDLAGLGQS SNSRNALLNA LLAVSCFHLQ SKYPRNYKLQ KYFLGLGIEL RNQASNFLRL 420
  421 CLNTKSSIPE KYKDVLTAIL SMNSIDVVWG TMADCQDHLA LCEDFVESRM KLRPNISEKT 480
  481 KTLHRIFSFL KLIQDSTALD KVRAKEIVIL PSEEDDNYKP LDTSNATTSS SEPRVDVVQE 540
  541 GLFREALNEN DGKIHIEFVK EPITNVSADS TPSSTTPPIF TNIATESYYN KSDISKLVSK 600
  601 TDENIIGTDS LYGLPNSLIL LFSDCVRIVR HNEYYNLTYL PVPRKFNELS LNFEKRLLKW 660
  661 KSEWNFHQEN SEGKSFINST AEALYHHTMS FYFSLIIYYF TMARSLNCQF LQNYVAKVLD 720
  721 HLNAMEELVD QKKVKIVPLI WQGFMAGCAC TDENRQQEFR RWAAKLAESG VGSYWGARQV 780
  781 MLEVWRRRKE DEPGDNWYSV YKDWEMNLML S

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [205-295]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ANDGVPPTPN LLDYDWNNLN ITGYEWISSE LRDDALLSAV TLQGHHLGHT QPQEISLEEN  60
   61 SNVVSGEEHV NAKEHGCAFE ADNQGSSTLP N

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [296-355]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KAASANDKLY QQNLKLLFQK NSSNSEEPDP QALIDDVFVN IEPRSLPASD LNKITLAPPN  60
   61 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [356-580]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EESRMPKSML ELTSYSSDLP PELVDIIPKT DLTVHGLARF LLNHYFNNVA DKMTVVVLEK  60
   61 NPWKTLYFPR ALMALGDLAG LGQSSNSRNA LLNALLAVSC FHLQSKYPRN YKLQKYFLGL 120
  121 GIELRNQASN FLRLCLNTKS SIPEKYKDVL TAILSMNSID VVWGTMADCQ DHLALCEDFV 180
  181 ESRMKLRPNI SEKTKTLHRI FSFLKLIQDS TALDKVRAKE IVILP

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [581-671]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SEEDDNYKPL DTSNATTSSS EPRVDVVQEG LFREALNEND GKIHIEFVKE PITNVSADST  60
   61 PSSTTPPIFT NIATESYYNK SDISKLVSKT D

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #7
Region A:
Residues: [672-880]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ENIIGTDSLY GLPNSLILLF SDCVRIVRHN EYYNLTYLPV PRKFNELSLN FEKRLLKWKS  60
   61 EWNFHQENSE GKSFINSTAE ALYHHTMSFY FSLIIYYFTM ARSLNCQFLQ NYVAKVLDHL 120
  121 NAMEELVDQK KVKIVPLIWQ GFMAGCACTD ENRQQEFRRW AAKLAESGVG SYWGARQVML 180
  181 EVWRRRKEDE PGDNWYSVYK DWEMNLMLS

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle