YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: NUP2
Organism: Saccharomyces cerevisiae
Length: 720 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for NUP2.

Description E-value Query
Range
Subject
Range
RBP2_MOUSE - E3 SUMO-protein ligase RanBP2 OS=Mus musculus GN=Ranbp2 PE=1 SV=1
2.0E-70 [205..717] [1436..1981]
RGPD6, RGPD5, RGPD8 - RANBP2-like and GRIP domain containing 8, RANBP2-like and GRIP domain containing 6, RANBP2-like and ...
5.0E-68 [237..717] [733..1168]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
2.0E-64 [205..717] [452..997]
NUP2_YEAST - Nucleoporin NUP2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=NUP2 PE=1 SV=2
NUP2 - Nucleoporin involved in nucleocytoplasmic transport, binds to either the nucleoplasmic or cytoplasmi...
8.0E-63 [1..720] [1..720]
gi|447739 - gi|447739|prf||1915304A nylB upstream ORF
2.0E-62 [5..717] [1380..2144]
RBP2_BOVIN - E3 SUMO-protein ligase RanBP2 (Fragment) OS=Bos taurus GN=RANBP2 PE=2 SV=2
8.0E-54 [160..719] [303..905]

Back

Predicted Domain #1
Region A:
Residues: [1-149]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAKRVADAQI QRETYDSNES DDDVTPSTKV ASSAVMNRRK IAMPKRRMAF KPFGSAKSDE  60
   61 TKQASSFSFL NRADGTGEAQ VDNSPTTESN SRLKALNLQF KAKVDDLVLG KPLADLRPLF 120
  121 TRYELYIKNI LEAPVKSIEN PTQTKGNDA

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [150-273]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KPAKVEDVQK SSDSSSEDEV KVEGPKFTID AKPPISDSVF SFGPKKENRK KDESDSENDI  60
   61 EIKGPEFKFS GTVSSDVFKL NPSTDKNEKK TETNAKPFSF SSATSTTEQT KSKNPLSLTE 120
  121 ATKT

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 14.0
Match: 1m2vB
Description: Sec24
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [274-279]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NVDNNS

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [505-585]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EDVKKPFSFG TSQPNNTPSF SFGKTTANLP ANSSTSPAPS IPSTGFKFSL PFEQKGSQTT  60
   61 TNDSKEESTT EATGNESQDA T

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 11.01
Match: 1l8mA
Description: No description for 1l8mA was found.

Predicted Domain #4
Region A:
Residues: [280-352]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KAEASFTFGT KHAADSQNNK PSFVFGQAAA KPSLEKSSFT FGSTTIEKKN DENSTSNSKP  60
   61 EKSSDSNDSN PSF

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 11.01
Match: 1l8mA
Description: No description for 1l8mA was found.

Predicted Domain #5
Region A:
Residues: [353-434]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SFSIPSKNTP DASKPSFSFG VPNSSKNETS KPVFSFGAAT PSAKEASQED DNNNVEKPSS  60
   61 KPAFNLISNA GTEKEKESKK DS

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 11.01
Match: 1l8mA
Description: No description for 1l8mA was found.

Predicted functions:

Term Confidence Notes
binding 3.29080729281876 bayes_pls_golite062009
protein binding 2.12168271674167 bayes_pls_golite062009
transcription regulator activity 2.10584700564436 bayes_pls_golite062009
nucleic acid binding 1.85794418941003 bayes_pls_golite062009
DNA binding 1.77960272183811 bayes_pls_golite062009
cytoskeletal protein binding 1.57773829313464 bayes_pls_golite062009
actin binding 1.43502308486445 bayes_pls_golite062009
transporter activity 1.28986800087234 bayes_pls_golite062009
signal transducer activity 1.15625292719687 bayes_pls_golite062009
molecular transducer activity 1.15625292719687 bayes_pls_golite062009
Ran GTPase binding 1.07023555877478 bayes_pls_golite062009
RNA binding 0.970967965545589 bayes_pls_golite062009
substrate-specific transporter activity 0.79883446648737 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 0.719838770435905 bayes_pls_golite062009
receptor activity 0.369903612832044 bayes_pls_golite062009
hydrolase activity 0.354215977182915 bayes_pls_golite062009
protein domain specific binding 0.18356841109571 bayes_pls_golite062009
structural molecule activity 0.160152014803717 bayes_pls_golite062009
transmembrane receptor activity 0.159652062741581 bayes_pls_golite062009
pyrophosphatase activity 0.0611639610381174 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides 0.0524559849408587 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 0.0498422520006935 bayes_pls_golite062009

Predicted Domain #6
Region A:
Residues: [435-504]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KPAFSFGISN GSESKDSDKP SLPSAVDGEN DKKEATKPAF SFGINTNTTK TADTKAPTFT  60
   61 FGSSALADNK 

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 11.01
Match: 1l8mA
Description: No description for 1l8mA was found.

Predicted Domain #7
Region A:
Residues: [586-720]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KVDATPEESK PINLQNGEED EVALFSQKAK LMTFNAETKS YDSRGVGEMK LLKKKDDPSK  60
   61 VRLLCRSDGM GNVLLNATVV DSFKYEPLAP GNDNLIKAPT VAADGKLVTY IVKFKQKEEG 120
  121 RSFTKAIEDA KKEMK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 134.190949
Match: 1rrpB_
Description: Nuclear pore complex protein Nup358
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle