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Protein Overview: NUP2_YEAST

General Information:
Name(s) found: NUP2_YEAST [Swiss-Prot]
Description(s) found:
  • Nucleoporin NUP2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=NUP2 PE=1 SV=2 [Swiss-Prot]
    • Organism: Saccharomyces cerevisiae S288c
    Length: 720 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAKRVADAQI QRETYDSNES DDDVTPSTKV ASSAVMNRRK IAMPKRRMAF KPFGSAKSDE  60
   61 TKQASSFSFL NRADGTGEAQ VDNSPTTESN SRLKALNLQF KAKVDDLVLG KPLADLRPLF 120
  121 TRYELYIKNI LEAPVKSIEN PTQTKGNDAK PAKVEDVQKS SDSSSEDEVK VEGPKFTIDA 180
  181 KPPISDSVFS FGPKKENRKK DESDSENDIE IKGPEFKFSG TVSSDVFKLN PSTDKNEKKT 240
  241 ETNAKPFSFS SATSTTEQTK SKNPLSLTEA TKTNVDNNSK AEASFTFGTK HAADSQNNKP 300
  301 SFVFGQAAAK PSLEKSSFTF GSTTIEKKND ENSTSNSKPE KSSDSNDSNP SFSFSIPSKN 360
  361 TPDASKPSFS FGVPNSSKNE TSKPVFSFGA ATPSAKEASQ EDDNNNVEKP SSKPAFNLIS 420
  421 NAGTEKEKES KKDSKPAFSF GISNGSESKD SDKPSLPSAV DGENDKKEAT KPAFSFGINT 480
  481 NTTKTADTKA PTFTFGSSAL ADNKEDVKKP FSFGTSQPNN TPSFSFGKTT ANLPANSSTS 540
  541 PAPSIPSTGF KFSLPFEQKG SQTTTNDSKE ESTTEATGNE SQDATKVDAT PEESKPINLQ 600
  601 NGEEDEVALF SQKAKLMTFN AETKSYDSRG VGEMKLLKKK DDPSKVRLLC RSDGMGNVLL 660
  661 NATVVDSFKY EPLAPGNDNL IKAPTVAADG KLVTYIVKFK QKEEGRSFTK AIEDAKKEMK 720
  721

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..149] deduced N/A No confident structure predictions are available.
    2 View Details [150..273] ORFEUS 14.0 Sec24
    3 View Details [274..279]
    [505..585]    		 ORFEUS 11.01 No description for 1l8mA was found.
    4 View Details [280..352] ORFEUS 11.01 No description for 1l8mA was found.
    5 View Details [353..434] ORFEUS 11.01 No description for 1l8mA was found.
    6 View Details [435..504] ORFEUS 11.01 No description for 1l8mA was found.
    7 View Details [586..720] PSI-BLAST 134.190949 Nuclear pore complex protein Nup358

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3 No functions predicted.
    4 No functions predicted.
    5
    Term Confidence Notes
  • binding
    		•  3.29080729281876 bayes_pls_golite062009
  • protein binding
    		•  2.12168271674167 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.10584700564436 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.85794418941003 bayes_pls_golite062009
  • DNA binding
    		•  1.77960272183811 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  1.57773829313464 bayes_pls_golite062009
  • actin binding
    		•  1.43502308486445 bayes_pls_golite062009
  • transporter activity
    		•  1.28986800087234 bayes_pls_golite062009
  • signal transducer activity
    		•  1.15625292719687 bayes_pls_golite062009
  • molecular transducer activity
    		•  1.15625292719687 bayes_pls_golite062009
  • Ran GTPase binding
    		•  1.07023555877478 bayes_pls_golite062009
  • RNA binding
    		•  0.970967965545589 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  0.79883446648737 bayes_pls_golite062009
  • general RNA polymerase II transcription factor activity
    		•  0.719838770435905 bayes_pls_golite062009
  • receptor activity
    		•  0.369903612832044 bayes_pls_golite062009
  • hydrolase activity
    		•  0.354215977182915 bayes_pls_golite062009
  • protein domain specific binding
    		•  0.18356841109571 bayes_pls_golite062009
  • structural molecule activity
    		•  0.160152014803717 bayes_pls_golite062009
  • transmembrane receptor activity
    		•  0.159652062741581 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  0.0611639610381174 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
    		•  0.0524559849408587 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    		•  0.0498422520006935 bayes_pls_golite062009
    6 No functions predicted.
    7 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle