| Protein: | NUP2 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 720 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for NUP2.
| Description | E-value | Query Range |
Subject Range |
|
|
2.0E-70 | [205..717] | [1436..1981] |
|
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5.0E-68 | [237..717] | [733..1168] |
|
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2.0E-64 | [205..717] | [452..997] |
|
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8.0E-63 | [1..720] | [1..720] |
|
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2.0E-62 | [5..717] | [1380..2144] |
|
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8.0E-54 | [160..719] | [303..905] |
|
Region A: Residues: [1-149] |
1 11 21 31 41 51
| | | | | |
1 MAKRVADAQI QRETYDSNES DDDVTPSTKV ASSAVMNRRK IAMPKRRMAF KPFGSAKSDE 60
61 TKQASSFSFL NRADGTGEAQ VDNSPTTESN SRLKALNLQF KAKVDDLVLG KPLADLRPLF 120
121 TRYELYIKNI LEAPVKSIEN PTQTKGNDA
|
| Detection Method: |  |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
SCOP Match |
SCOP Description | ||
| View | Download | 0.625 | a.1.1 | Globin-like |
| View | Download | 0.701 | f.1.4 | Bcl-2 inhibitors of programmed cell death |
| View | Download | 0.657 | f.18.1 | F1F0 ATP synthase subunit A |
| View | Download | 0.701 | f.1.4 | Bcl-2 inhibitors of programmed cell death |
| View | Download | 0.657 | f.18.1 | F1F0 ATP synthase subunit A |
| View | Download | 0.632 | a.25.2 | Thermoplasma ferritin-like 4-helical bundle |
| View | Download | 0.632 | a.25.2 | Thermoplasma ferritin-like 4-helical bundle |
| View | Download | 0.625 | a.1.1 | Globin-like |
| View | Download | 0.614 | a.1.1 | Globin-like |
| View | Download | 0.614 | a.1.1 | Globin-like |
| View | Download | 0.607 | a.1.1 | Globin-like |
| View | Download | 0.591 | a.25.1 | Ferritin-like |
| View | Download | 0.590 | f.1.4 | Bcl-2 inhibitors of programmed cell death |
| View | Download | 0.551 | a.78.1 | Fatty acid responsive transcription factor FadR, C-terminal domain |
| View | Download | 0.511 | a.1.1 | Globin-like |
| View | Download | 0.504 | a.1.1 | Globin-like |
| View | Download | 0.460 | a.63.1 | Apolipophorin-III |
| View | Download | 0.460 | a.24.1 | Apolipoprotein |
| View | Download | 0.451 | f.1.4 | Bcl-2 inhibitors of programmed cell death |
| View | Download | 0.448 | a.24.2 | Aspartate receptor, ligand-binding domain |
| View | Download | 0.445 | a.60.10 | Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain |
| View | Download | 0.442 | a.136.1 | Repressor of bacterial conjugation FinO |
| View | Download | 0.438 | a.24.2 | Aspartate receptor, ligand-binding domain |
| View | Download | 0.410 | a.24.1 | Apolipoprotein |
| View | Download | 0.408 | a.29.4 | RecG, N-terminal domain |
| View | Download | 0.406 | a.63.1 | Apolipophorin-III |
| View | Download | 0.401 | a.25.1 | Ferritin-like |
| View | Download | 0.400 | d.110.4 | SNARE-like |
| View | Download | 0.391 | f.36.1 | Neurotransmitter-gated ion-channel pransmembrane pore |
| View | Download | 0.389 | d.134.1 | Sulfite reductase hemoprotein (SiRHP), domains 2 and 4 |
| View | Download | 0.387 | a.25.1 | Ferritin-like |
| View | Download | 0.382 | a.25.1 | Ferritin-like |
| View | Download | 0.368 | a.7.1 | Spectrin repeat |
| View | Download | 0.367 | a.7.1 | Spectrin repeat |
| View | Download | 0.363 | a.91.1 | Regulator of G-protein signalling, RGS |
| View | Download | 0.356 | f.1.4 | Bcl-2 inhibitors of programmed cell death |
| View | Download | 0.353 | a.45.1 | Glutathione S-transferase (GST), C-terminal domain |
| View | Download | 0.353 | a.48.1 | N-terminal domain of cbl (N-cbl) |
| View | Download | 0.348 | a.47.2 | t-snare proteins |
| View | Download | 0.347 | a.24.1 | Apolipoprotein |
| View | Download | 0.344 | a.24.1 | Apolipoprotein |
| View | Download | 0.340 | a.152.1 | Antioxidant defence protein AhpD |
| View | Download | 0.332 | a.24.3 | Cytochromes |
| View | Download | 0.329 | d.20.1 | UBC-like |
| View | Download | 0.329 | f.18.1 | F1F0 ATP synthase subunit A |
| View | Download | 0.327 | a.26.1 | 4-helical cytokines |
| View | Download | 0.323 | f.36.1 | Neurotransmitter-gated ion-channel pransmembrane pore |
| View | Download | 0.321 | b.82.4 | Regulatory protein AraC |
| View | Download | 0.320 | a.39.2 | Insect pheromon/odorant-binding proteins |
| View | Download | 0.314 | a.48.1 | N-terminal domain of cbl (N-cbl) |
| View | Download | 0.307 | i.11.1 | Computational models partly based on NMR data |
| View | Download | 0.305 | a.4.6 | C-terminal effector domain of the bipartite response regulators |
| View | Download | 0.299 | a.24.4 | Hemerythrin |
| View | Download | 0.297 | a.48.1 | N-terminal domain of cbl (N-cbl) |
| View | Download | 0.290 | a.121.1 | Tetracyclin repressor-like, C-terminal domain |
| View | Download | 0.287 | a.24.3 | Cytochromes |
| View | Download | 0.286 | c.45.1 | (Phosphotyrosine protein) phosphatases II |
| View | Download | 0.285 | a.73.1 | Retrovirus capsid protein, N-terminal core domain |
| View | Download | 0.281 | a.47.2 | t-snare proteins |
| View | Download | 0.273 | a.23.1 | HSC20 (HSCB), C-terminal oligomerisation domain |
| View | Download | 0.272 | a.24.9 | alpha-catenin/vinculin |
| View | Download | 0.271 | a.91.1 | Regulator of G-protein signalling, RGS |
| View | Download | 0.270 | a.24.9 | alpha-catenin/vinculin |
| View | Download | 0.269 | a.168.1 | GEF domain of SopE toxin |
| View | Download | 0.261 | a.48.1 | N-terminal domain of cbl (N-cbl) |
| View | Download | 0.258 | f.35.1 | Multidrug efflux transporter AcrB transmembrane domain |
| View | Download | 0.257 | a.63.1 | Apolipophorin-III |
| View | Download | 0.255 | f.36.1 | Neurotransmitter-gated ion-channel pransmembrane pore |
| View | Download | 0.252 | d.67.3 | Ribosome recycling factor, RRF |
| View | Download | 0.250 | a.133.1 | Phospholipase A2, PLA2 |
| View | Download | 0.250 | f.36.1 | Neurotransmitter-gated ion-channel pransmembrane pore |
| View | Download | 0.247 | a.121.1 | Tetracyclin repressor-like, C-terminal domain |
| View | Download | 0.242 | d.87.2 | CO dehydrogenase flavoprotein C-terminal domain-like |
| View | Download | 0.241 | d.54.1 | Enolase N-terminal domain-like |
| View | Download | 0.240 | d.87.2 | CO dehydrogenase flavoprotein C-terminal domain-like |
| View | Download | 0.240 | a.26.1 | 4-helical cytokines |
| View | Download | 0.238 | a.48.1 | N-terminal domain of cbl (N-cbl) |
| View | Download | 0.237 | d.110.4 | SNARE-like |
| View | Download | 0.234 | a.24.17 | Group V grass pollen allergen |
| View | Download | 0.231 | f.36.1 | Neurotransmitter-gated ion-channel pransmembrane pore |
| View | Download | 0.228 | a.3.1 | Cytochrome c |
| View | Download | 0.225 | a.39.1 | EF-hand |
| View | Download | 0.223 | a.29.2 | Bromodomain |
| View | Download | 0.221 | a.152.1 | Antioxidant defence protein AhpD |
| View | Download | 0.220 | a.24.16 | Nucleotidyltransferase substrate binding subunit/domain |
| View | Download | 0.218 | a.60.10 | Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain |
| View | Download | 0.217 | f.36.1 | Neurotransmitter-gated ion-channel pransmembrane pore |
| View | Download | 0.214 | a.126.1 | Serum albumin-like |
| View | Download | 0.209 | f.36.1 | Neurotransmitter-gated ion-channel pransmembrane pore |
| View | Download | 0.208 | a.24.10 | Histidine-containing phosphotransfer domain, HPT domain |
| View | Download | 0.208 | f.36.1 | Neurotransmitter-gated ion-channel pransmembrane pore |
| View | Download | 0.203 | a.7.8 | GAT domain |
| View | Download | 0.202 | a.66.1 | Transducin (alpha subunit), insertion domain |
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Region A: Residues: [150-273] |
1 11 21 31 41 51
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1 KPAKVEDVQK SSDSSSEDEV KVEGPKFTID AKPPISDSVF SFGPKKENRK KDESDSENDI 60
61 EIKGPEFKFS GTVSSDVFKL NPSTDKNEKK TETNAKPFSF SSATSTTEQT KSKNPLSLTE 120
121 ATKT
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| Detection Method: | |
| Confidence: | 14.0 |
| Match: | 1m2vB |
| Description: | Sec24 |
Matching Structure (courtesy of the PDB): |
|
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Region A: Residues: [274-279] |
1 11 21 31 41 51
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1 NVDNNS
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Region B: Residues: [505-585] |
1 11 21 31 41 51
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1 EDVKKPFSFG TSQPNNTPSF SFGKTTANLP ANSSTSPAPS IPSTGFKFSL PFEQKGSQTT 60
61 TNDSKEESTT EATGNESQDA T
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| Detection Method: | |
| Confidence: | 11.01 |
| Match: | 1l8mA |
| Description: | No description for 1l8mA was found. |
|
Region A: Residues: [280-352] |
1 11 21 31 41 51
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1 KAEASFTFGT KHAADSQNNK PSFVFGQAAA KPSLEKSSFT FGSTTIEKKN DENSTSNSKP 60
61 EKSSDSNDSN PSF
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| Detection Method: | |
| Confidence: | 11.01 |
| Match: | 1l8mA |
| Description: | No description for 1l8mA was found. |
|
Region A: Residues: [353-434] |
1 11 21 31 41 51
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1 SFSIPSKNTP DASKPSFSFG VPNSSKNETS KPVFSFGAAT PSAKEASQED DNNNVEKPSS 60
61 KPAFNLISNA GTEKEKESKK DS
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| Detection Method: | |
| Confidence: | 11.01 |
| Match: | 1l8mA |
| Description: | No description for 1l8mA was found. |
| Term | Confidence | Notes |
| binding | 3.29080729281876 | bayes_pls_golite062009 |
| protein binding | 2.12168271674167 | bayes_pls_golite062009 |
| transcription regulator activity | 2.10584700564436 | bayes_pls_golite062009 |
| nucleic acid binding | 1.85794418941003 | bayes_pls_golite062009 |
| DNA binding | 1.77960272183811 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 1.57773829313464 | bayes_pls_golite062009 |
| actin binding | 1.43502308486445 | bayes_pls_golite062009 |
| transporter activity | 1.28986800087234 | bayes_pls_golite062009 |
| signal transducer activity | 1.15625292719687 | bayes_pls_golite062009 |
| molecular transducer activity | 1.15625292719687 | bayes_pls_golite062009 |
| Ran GTPase binding | 1.07023555877478 | bayes_pls_golite062009 |
| RNA binding | 0.970967965545589 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 0.79883446648737 | bayes_pls_golite062009 |
| general RNA polymerase II transcription factor activity | 0.719838770435905 | bayes_pls_golite062009 |
| receptor activity | 0.369903612832044 | bayes_pls_golite062009 |
| hydrolase activity | 0.354215977182915 | bayes_pls_golite062009 |
| protein domain specific binding | 0.18356841109571 | bayes_pls_golite062009 |
| structural molecule activity | 0.160152014803717 | bayes_pls_golite062009 |
| transmembrane receptor activity | 0.159652062741581 | bayes_pls_golite062009 |
| pyrophosphatase activity | 0.0611639610381174 | bayes_pls_golite062009 |
| hydrolase activity, acting on acid anhydrides | 0.0524559849408587 | bayes_pls_golite062009 |
| hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | 0.0498422520006935 | bayes_pls_golite062009 |
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Region A: Residues: [435-504] |
1 11 21 31 41 51
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1 KPAFSFGISN GSESKDSDKP SLPSAVDGEN DKKEATKPAF SFGINTNTTK TADTKAPTFT 60
61 FGSSALADNK
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| Detection Method: | |
| Confidence: | 11.01 |
| Match: | 1l8mA |
| Description: | No description for 1l8mA was found. |
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Region A: Residues: [586-720] |
1 11 21 31 41 51
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1 KVDATPEESK PINLQNGEED EVALFSQKAK LMTFNAETKS YDSRGVGEMK LLKKKDDPSK 60
61 VRLLCRSDGM GNVLLNATVV DSFKYEPLAP GNDNLIKAPT VAADGKLVTY IVKFKQKEEG 120
121 RSFTKAIEDA KKEMK
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| Detection Method: | |
| Confidence: | 134.190949 |
| Match: | 1rrpB_ |
| Description: | Nuclear pore complex protein Nup358 |
Matching Structure (courtesy of the PDB): |
|
