| Protein: | IRC20 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 1556 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for IRC20.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..1556] | [1..1556] |
|
|
0.0 | [21..1030] | [1635..2630] |
|
|
0.0 | [35..1040] | [121..1071] |
|
|
0.0 | [130..935] | [513..1258] |
|
Region A: Residues: [1-282] |
1 11 21 31 41 51
| | | | | |
1 MSAVGALLAR EYNVTAEKCD FFLENGSFDS VIAALPALNQ EQETVTQKVS KNGKELINVA 60
61 SVNIEIPERI SLSNNGRQLF KFIVDIEILP CENDNEATLV VSSDSVSLFQ IGFKMENNSK 120
121 IAVDKQLPLI LDICAHKNQE RALRNQLENR KSLERKPSRK RRKKNSNVND PEKLLKSRIH 180
181 ELSLSYKDFE CSPVVFRYND SSLTWVLSFN LKLKFLNNKF NRFSVEANQI LDLTFSNRDE 240
241 NEFERYHKHS HIHSNFIQKQ FISQILEYSK DRLSKIKPFL PQ
|
| Detection Method: |  |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
|
Region A: Residues: [283-718] |
1 11 21 31 41 51
| | | | | |
1 SIPDLKVNLL PFQRESVEWM LIKEGHGNSL SDTPTVIDEV GLIDFMNEYY AYGYELIARS 60
61 PDEVGPSLLW NKLTGYILTT EDAAHLYNQY RKERLSGDYP VCAKGVLAEE MGLGKTIEIL 120
121 SLILLNRRKL KDSEATFIDD ENRTITKTKT TLIICPNAIL KQWLEEIELH ANSLKWYTYR 180
181 GYNEIMKDCK TVDEAVQQLC QYDIIVTSYN IIATEVHHAE FNRSIRSRRL KSPKYDYSSP 240
241 LALMQFYRII LDEVQMLRSS STYSAKCTSL LHRIHTWGVS GTPIQNIYNF RMIMSYLKLH 300
301 PFCDEVDFIR TLQEEIKLRN EAKDYTSNDF VCQLKGVRFS IKDCMNIFYR YDLCIRHSKA 360
361 NVASQIHIPR QHNFIIPLEF APIEWDNYLN LWNNFLELSG YNSDGSGSPR VSNAFLNEWL 420
421 SRLRYICCHA LFPEIL
|
| Detection Method: | |
| Confidence: | 8.638272 |
| Match: | PF00176 |
| Description: | SNF2 family N-terminal domain |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
| Term | Confidence | Notes |
| binding | 1.68908265056856 | bayes_pls_golite062009 |
| chromatin binding | 0.901919966053279 | bayes_pls_golite062009 |
| protein binding | 0.40894004702539 | bayes_pls_golite062009 |
| transcription regulator activity | 0.280209685341429 | bayes_pls_golite062009 |
| transcription repressor activity | 0.0640203857327035 | bayes_pls_golite062009 |
|
Region A: Residues: [719-878] |
1 11 21 31 41 51
| | | | | |
1 STRQKRLHGH LSRISNIDDI LISMRMDAFD SLIGYYRERF HLSIKQAQYE LEISNTPAKA 60
61 LESFIKIRDD LMIHIRQKFN VEDPFDKSLN LSEDEDEHMD ERFGEKETSS GDESDREING 120
121 AKNHDNHNND GMLSNHLKKK GLRAMMNLLH DCYFFLGSVY
|
| Detection Method: | |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
| Term | Confidence | Notes |
| binding | 1.26687146372087 | bayes_pls_golite062009 |
| nucleoside-triphosphatase activity | 0.420384345567397 | bayes_pls_golite062009 |
| pyrophosphatase activity | 0.411077559082206 | bayes_pls_golite062009 |
| hydrolase activity, acting on acid anhydrides | 0.399864241228259 | bayes_pls_golite062009 |
| hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | 0.398496265411009 | bayes_pls_golite062009 |
| catalytic activity | 0.234613562021476 | bayes_pls_golite062009 |
| hydrolase activity | 0.216831145240405 | bayes_pls_golite062009 |
|
Region A: Residues: [879-1236] |
1 11 21 31 41 51
| | | | | |
1 YNLGTRKLEE ADDKHRKEKT EEVVYSDVFP KNELEEIEEN RLLEQENYAN AEILRKSILS 60
61 SEARKVDMTI KMARTKFAPM TSNIPLRLIN IEFDHKNDYS SNLAVSRCFK SLSKLIEGLN 120
121 EQTKNFNELL DELLIIIYEP VHRTEDDDST NKIIGNEEYS TSIDSQDKIF SLLGCLEIIL 180
181 QNRDNILTSE SEVKIPKHLV PEGSIISKYQ KQLLNSLRLI SGTPLRTVFD ELKNSRIVRR 240
241 ISSSNESEST IQNFEDYLLQ YEVESKSLFK YNKQVRESLK ILGSIYNAKT EYYSQLQRIS 300
301 DSLVSLHSLS APQLSHLIRT INKSLGGTLD AKINNIESRL IYLKNLSRLK DTLNDNQI
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
|
Region A: Residues: [1237-1276] |
1 11 21 31 41 51
| | | | | |
1 LSCSICLGEV EIGAIIKCGH YFCKSCILTW LRAHSKCPIC
|
| Detection Method: | |
| Confidence: | 7.568636 |
| Match: | PF00097 |
| Description: | Zinc finger, C3HC4 type (RING finger) |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
| Term | Confidence | Notes |
| binding | 1.33062723118115 | bayes_pls_golite062009 |
| protein binding | 0.278046871496516 | bayes_pls_golite062009 |
|
Region A: Residues: [1277-1476] |
1 11 21 31 41 51
| | | | | |
1 KGFCSISEVY NFKFKNSTEK REKEIQEPRR EGADSSQDNS NENSIISNMS EVEKLFGNKY 60
61 EQFHQINEVH QIHIKESFGA KIDFVIKLIS YLRLKSEQEN ADPPQVILYS QKTEYLKVIG 120
121 KVLKLYHIEH LACLSNTANV GETINNFKRQ PSVTCLLLNV KTLGAGLNLI NAKHIFLLDP 180
181 ILNNSDELQA MGRNNRIGQD
|
| Detection Method: | |
| Confidence: | 4.522879 |
| Match: | 1hv8A_ |
| Description: | Putative DEAD box RNA helicase |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [1477-1556] |
1 11 21 31 41 51
| | | | | |
1 EETFVWNFMI RNTVEENILR YKCILEERKR KEKSKKGDKY DEAQDETDNE ESDDAKFEIS 60
61 VVDQEVSNEH LWNCFFHGSD
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
SCOP Match |
SCOP Description | ||
| View | Download | 0.450 | a.59.1 | PAH2 domain |
| View | Download | 0.377 | a.2.7 | tRNA-binding arm |
| View | Download | 0.342 | d.137.1 | Monooxygenase (hydroxylase) regulatory protein |
| View | Download | 0.362 | f.15.1 | Small-conductance potassium channel |
| View | Download | 0.518 | i.1.1 | Ribosome and ribosomal fragments |
| View | Download | 0.342 | d.58.17 | Metal-binding domain |
| View | Download | 0.323 | a.12.1 | Kix domain of CBP (creb binding protein) |
| View | Download | 0.310 | a.77.1 | DEATH domain |
| View | Download | 0.268 | a.4.9 | Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 |
| View | Download | 0.265 | a.3.1 | Cytochrome c |
| View | Download | 0.261 | a.24.7 | FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) |
| View | Download | 0.260 | a.26.1 | 4-helical cytokines |
| View | Download | 0.259 | d.58.7 | RNA-binding domain, RBD |
| View | Download | 0.257 | a.24.17 | Group V grass pollen allergen |
| View | Download | 0.244 | d.58.49 | YajQ-like |
| View | Download | 0.244 | a.13.1 | alpha-2-Macroglobulin receptor associated protein (RAP) domain 1 |
| View | Download | 0.243 | a.56.1 | CO dehydrogenase ISP C-domain like |
| View | Download | 0.239 | b.84.2 | Rudiment single hybrid motif |
| View | Download | 0.219 | d.58.24 | CheY-binding domain of CheA |
| View | Download | 0.218 | a.151.1 | Glutamyl tRNA-reductase dimerization domain |
| View | Download | 0.213 | d.58.17 | Metal-binding domain |
| View | Download | 0.211 | f.17.1 | F1F0 ATP synthase subunit C |
| View | Download | 0.206 | a.35.1 | lambda repressor-like DNA-binding domains |
| View | Download | 0.206 | a.51.1 | Cytochrome c oxidase subunit h |
| View | Download | 0.201 | a.3.1 | Cytochrome c |
| View | Download | 0.200 | a.7.7 | BAG domain |
