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View Structure Prediction Details

Protein: UBI4
Organism: Saccharomyces cerevisiae
Length: 381 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for UBI4.

Description E-value Query
Range		 Subject
Range
gi|25294251, gi|... - gi|7267292|emb|CAB81074.1| polyubiquitin (ubq10) [Arabidopsis thaliana], gi|30680061|ref|NP_849301.1...
 0.0 [1..380] [1..380]
gi|940395 - gi|940395|dbj|BAA09853.1| polyubiquitin [Cricetulus sp.]
UBIQP_CRIGR - Polyubiquitin OS=Cricetulus griseus PE=2 SV=2
 0.0 [1..380] [153..532]
gi|149254471, gi... - gi|94375381|ref|XP_001002053.1| PREDICTED: similar to ubiquitin C isoform 22 [Mus musculus], gi|9437...
 0.0 [1..380] [153..532]
gi|2627131 - gi|2627131|dbj|BAA23487.1| polyubiquitin [Cricetulus griseus]
 0.0 [1..380] [77..456]
UBC_RAT - Polyubiquitin-C OS=Rattus norvegicus GN=Ubc PE=1 SV=1
 0.0 [1..380] [305..684]
gi|510473 - gi|510473|emb|CAA52416.1| polyubiquitin [Artemia franciscana]
 0.0 [1..381] [305..685]

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Predicted Domain #1
Region A:
Residues: [1-76] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQIFVKTLTG KTITLEVESS DTIDNVKSKI QDKEGIPPDQ QRLIFAGKQL EDGRTLSDYN  60
   61 IQKESTLHLV LRLRGG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 181.68867
Match: 1nddA_
Description: Nedd8
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
small conjugating protein ligase activity 7.96815122865454 bayes_pls_golite062009
ubiquitin-protein ligase activity 7.5865326390755 bayes_pls_golite062009
acid-amino acid ligase activity 6.96506647680367 bayes_pls_golite062009
ligase activity, forming carbon-nitrogen bonds 5.87890364671564 bayes_pls_golite062009
structural constituent of ribosome 5.80275625219016 bayes_pls_golite062009
structural molecule activity 5.37716040292459 bayes_pls_golite062009
ligase activity 2.98370000660434 bayes_pls_golite062009
protein binding 2.9188688008729 bayes_pls_golite062009
binding 2.786655943372 bayes_pls_golite062009
transcription regulator activity 2.21955949922709 bayes_pls_golite062009
tubulin binding 2.21127283188349 bayes_pls_golite062009
cytoskeletal protein binding 2.20811136250556 bayes_pls_golite062009
protein tag 2.15059229834935 bayes_pls_golite062009
nucleic acid binding 1.9984951714209 bayes_pls_golite062009
microtubule binding 1.92602521631666 bayes_pls_golite062009
DNA binding 1.86539227646379 bayes_pls_golite062009
receptor binding 1.09091623056284 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 1.06193722939839 bayes_pls_golite062009
SUMO ligase activity 0.80391127659342 bayes_pls_golite062009
RNA polymerase II transcription factor activity 0.62324312069889 bayes_pls_golite062009
hydrolase activity 0.614233748923048 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 0.536856055841234 bayes_pls_golite062009
kinase activity 0.506057697290914 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.410719674374641 bayes_pls_golite062009
RNA binding 0.359926300264681 bayes_pls_golite062009
protein kinase activity 0.325253662829604 bayes_pls_golite062009
peptidase inhibitor activity 0.27796076785312 bayes_pls_golite062009
enzyme binding 0.240262781026149 bayes_pls_golite062009
endopeptidase inhibitor activity 0.189489510504993 bayes_pls_golite062009
structure-specific DNA binding 0.0788219117963673 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [77-150] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQIFVKTLTG KTITLEVESS DTIDNVKSKI QDKEGIPPDQ QRLIFAGKQL EDGRTLSDYN  60
   61 IQKESTLHLV LRLR

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 14.91
Match: 1nddA
Description: Nedd8
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
small conjugating protein ligase activity 7.77976521481104 bayes_pls_golite062009
ubiquitin-protein ligase activity 7.45825282569124 bayes_pls_golite062009
acid-amino acid ligase activity 6.82424077726436 bayes_pls_golite062009
ligase activity, forming carbon-nitrogen bonds 5.78164148882937 bayes_pls_golite062009
structural constituent of ribosome 5.77326793355348 bayes_pls_golite062009
structural molecule activity 5.36311620867914 bayes_pls_golite062009
ligase activity 2.93949076291021 bayes_pls_golite062009
protein binding 2.78014377544701 bayes_pls_golite062009
binding 2.70872150536621 bayes_pls_golite062009
transcription regulator activity 2.23822335492051 bayes_pls_golite062009
cytoskeletal protein binding 2.11984570584255 bayes_pls_golite062009
tubulin binding 2.03607606145909 bayes_pls_golite062009
nucleic acid binding 2.02209816078273 bayes_pls_golite062009
DNA binding 1.8833926783115 bayes_pls_golite062009
microtubule binding 1.75926256048235 bayes_pls_golite062009
protein tag 1.64936739586738 bayes_pls_golite062009
receptor binding 1.07983643886476 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 1.04462787665591 bayes_pls_golite062009
hydrolase activity 0.633589926944629 bayes_pls_golite062009
RNA polymerase II transcription factor activity 0.624731467637361 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 0.549761413791307 bayes_pls_golite062009
kinase activity 0.520011006272513 bayes_pls_golite062009
SUMO ligase activity 0.469920108401949 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.426082194130922 bayes_pls_golite062009
RNA binding 0.3655923364304 bayes_pls_golite062009
protein kinase activity 0.336252604607827 bayes_pls_golite062009
peptidase inhibitor activity 0.270602640718893 bayes_pls_golite062009
endopeptidase inhibitor activity 0.181054590240182 bayes_pls_golite062009
enzyme binding 0.147520546067615 bayes_pls_golite062009
structure-specific DNA binding 0.0623044995795676 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [151-215] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GGMQIFVKTL TGKTITLEVE SSDTIDNVKS KIQDKEGIPP DQQRLIFAGK QLEDGRTLSD  60
   61 YNIQK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 193.37734
Match: 1gjzA_
Description: Ubiquitin
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
small conjugating protein ligase activity 7.96815122865454 bayes_pls_golite062009
ubiquitin-protein ligase activity 7.5865326390755 bayes_pls_golite062009
acid-amino acid ligase activity 6.96506647680367 bayes_pls_golite062009
ligase activity, forming carbon-nitrogen bonds 5.87890364671564 bayes_pls_golite062009
structural constituent of ribosome 5.80275625219016 bayes_pls_golite062009
structural molecule activity 5.37716040292459 bayes_pls_golite062009
ligase activity 2.98370000660434 bayes_pls_golite062009
protein binding 2.9188688008729 bayes_pls_golite062009
binding 2.786655943372 bayes_pls_golite062009
transcription regulator activity 2.21955949922709 bayes_pls_golite062009
tubulin binding 2.21127283188349 bayes_pls_golite062009
cytoskeletal protein binding 2.20811136250556 bayes_pls_golite062009
protein tag 2.15059229834935 bayes_pls_golite062009
nucleic acid binding 1.9984951714209 bayes_pls_golite062009
microtubule binding 1.92602521631666 bayes_pls_golite062009
DNA binding 1.86539227646379 bayes_pls_golite062009
receptor binding 1.09091623056284 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 1.06193722939839 bayes_pls_golite062009
SUMO ligase activity 0.80391127659342 bayes_pls_golite062009
RNA polymerase II transcription factor activity 0.62324312069889 bayes_pls_golite062009
hydrolase activity 0.614233748923048 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 0.536856055841234 bayes_pls_golite062009
kinase activity 0.506057697290914 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.410719674374641 bayes_pls_golite062009
RNA binding 0.359926300264681 bayes_pls_golite062009
protein kinase activity 0.325253662829604 bayes_pls_golite062009
peptidase inhibitor activity 0.27796076785312 bayes_pls_golite062009
enzyme binding 0.240262781026149 bayes_pls_golite062009
endopeptidase inhibitor activity 0.189489510504993 bayes_pls_golite062009
structure-specific DNA binding 0.0788219117963673 bayes_pls_golite062009

Predicted Domain #4
Region A:
Residues: [216-304] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ESTLHLVLRL RGGMQIFVKT LTGKTITLEV ESSDTIDNVK SKIQDKEGIP PDQQRLIFAG  60
   61 KQLEDGRTLS DYNIQKESTL HLVLRLRGG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 337.07631
Match: 1aarA_
Description: Ubiquitin
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [305-381] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQIFVKTLTG KTITLEVESS DTIDNVKSKI QDKEGIPPDQ QRLIFAGKQL EDGRTLSDYN  60
   61 IQKESTLHLV LRLRGGN

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 13.19
Match: 1j8cA
Description: Ubiquitin-like N-terminal domain of PLIC-2
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
small conjugating protein ligase activity 7.96815122865454 bayes_pls_golite062009
ubiquitin-protein ligase activity 7.5865326390755 bayes_pls_golite062009
acid-amino acid ligase activity 6.96506647680367 bayes_pls_golite062009
ligase activity, forming carbon-nitrogen bonds 5.87890364671564 bayes_pls_golite062009
structural constituent of ribosome 5.80275625219016 bayes_pls_golite062009
structural molecule activity 5.37716040292459 bayes_pls_golite062009
ligase activity 2.98370000660434 bayes_pls_golite062009
protein binding 2.9188688008729 bayes_pls_golite062009
binding 2.786655943372 bayes_pls_golite062009
transcription regulator activity 2.21955949922709 bayes_pls_golite062009
tubulin binding 2.21127283188349 bayes_pls_golite062009
cytoskeletal protein binding 2.20811136250556 bayes_pls_golite062009
protein tag 2.15059229834935 bayes_pls_golite062009
nucleic acid binding 1.9984951714209 bayes_pls_golite062009
microtubule binding 1.92602521631666 bayes_pls_golite062009
DNA binding 1.86539227646379 bayes_pls_golite062009
receptor binding 1.09091623056284 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 1.06193722939839 bayes_pls_golite062009
SUMO ligase activity 0.80391127659342 bayes_pls_golite062009
RNA polymerase II transcription factor activity 0.62324312069889 bayes_pls_golite062009
hydrolase activity 0.614233748923048 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 0.536856055841234 bayes_pls_golite062009
kinase activity 0.506057697290914 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.410719674374641 bayes_pls_golite062009
RNA binding 0.359926300264681 bayes_pls_golite062009
protein kinase activity 0.325253662829604 bayes_pls_golite062009
peptidase inhibitor activity 0.27796076785312 bayes_pls_golite062009
enzyme binding 0.240262781026149 bayes_pls_golite062009
endopeptidase inhibitor activity 0.189489510504993 bayes_pls_golite062009
structure-specific DNA binding 0.0788219117963673 bayes_pls_golite062009
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle