YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: ASH1
Organism: Saccharomyces cerevisiae
Length: 588 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ASH1.

Description E-value Query
Range
Subject
Range
ASH1_YEAST - Transcriptional regulatory protein ASH1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=...
ASH1 - Zinc-finger inhibitor of HO transcription; mRNA is localized and translated in the distal tip of ana...
0.0 [1..588] [1..588]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
1.0E-52 [220..563] [361..728]
AREA_EMENI - Nitrogen regulatory protein areA OS=Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / ...
AREA_EMENI - Nitrogen regulatory protein areA OS=Emericella nidulans GN=areA PE=1 SV=2
3.0E-52 [220..563] [361..728]
GAT5B_XENLA - GATA-binding factor 5-B OS=Xenopus laevis GN=gata5-b PE=2 SV=1
3.0E-42 [330..580] [9..263]
AREA_ASPNG - Nitrogen regulatory protein areA OS=Aspergillus niger GN=areA PE=3 SV=1
2.0E-41 [220..563] [366..731]
gi|12802699 - gi|12802699|gb|AAK08066.1|AF320305_1 AreA [Aspergillus oryzae]
6.0E-39 [220..563] [342..707]
GATA3_MOUSE - Trans-acting T-cell-specific transcription factor GATA-3 OS=Mus musculus GN=Gata3 PE=1 SV=1
5.0E-38 [308..580] [30..342]

Back

Predicted Domain #1
Region A:
Residues: [1-236]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSLYIKTPL HALSAGPDSH ANSSYYDNLL LPSFSNLSSN ISRNNITTDN NINSASPRKY  60
   61 SFHSLNVSPI LSPISLANEI LGKKSNTAPA SPHHMDYNPI SSLTPGNSPE FNKASLSQIS 120
  121 FTNPLNYGSG LGFSSNSQPR LPLLDRLSSV SLSKRPERPQ QSLPSLRHLQ LLPSPLLQEN 180
  181 AARFPDTSKR TSNWKTDLTH WCKDTNYQDY VKIREEVAHF KPLSIPNLTN NQNNDS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [237-475]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FNYGKELEST RSSKFHSPSK ESFDRTKLIP SILEAKDQFK DLSNNAWSIT PPVTPPMSPP  60
   61 TNRTMERTTL RGVEASFFEG KSSNNDSIFN PIISEKLVQE VKHQRQLRGN SFPMPNASHK 120
  121 KTNSFKALQI KKLLANRDIL SNNSKSNVRK PSKNKISKQA SNVFGNTARQ LVMKLDNASY 180
  181 SSVSASSSPS PSTPTKSGKM RSRSSSPVRP KAYTPSPRSP NYHRFALDSP PQSPRRSSN

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [476-588]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SSITKKGSRR SSGSSPTRHT TRVCVSCHSS DSPCWRPSWS PRKQDQLCNS CGLRYKKTHT  60
   61 RCLNDLCRKI PTKGEINIMK SNGIDKEFVP ERNCEIEGYR CLFCNYITET VEN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 14.221849
Match: 4gatA_
Description: Erythroid transcription factor GATA-1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 4.00967542385368 bayes_pls_golite062009
DNA binding 3.60745514727532 bayes_pls_golite062009
nucleic acid binding 3.47256374293954 bayes_pls_golite062009
binding 2.96409924710655 bayes_pls_golite062009
transcription factor activity 2.90769972671972 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 2.55186574506963 bayes_pls_golite062009
RNA polymerase II transcription factor activity 2.40923942043513 bayes_pls_golite062009
transcription repressor activity 1.88834375049208 bayes_pls_golite062009
sequence-specific DNA binding 1.62841402245495 bayes_pls_golite062009
transcription activator activity 1.62405765585032 bayes_pls_golite062009
ligand-dependent nuclear receptor activity 1.49515149729803 bayes_pls_golite062009
protein binding 1.39455913713025 bayes_pls_golite062009
transcription factor binding 1.38523780690867 bayes_pls_golite062009
specific RNA polymerase II transcription factor activity 1.26452462867497 bayes_pls_golite062009
structural constituent of ribosome 1.14370842685155 bayes_pls_golite062009
structural molecule activity 1.03433454627943 bayes_pls_golite062009
transcription coactivator activity 0.61572149323953 bayes_pls_golite062009
transcription cofactor activity 0.58115018700114 bayes_pls_golite062009
cytoskeletal protein binding 0.405267736307896 bayes_pls_golite062009
catalytic activity 0.101795606736461 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle