| Protein: | ZAP1 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 880 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ZAP1.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [7..879] | [283..1134] |
|
|
0.0 | [231..850] | [265..876] |
|
|
0.0 | [6..879] | [96..1016] |
|
Region A: Residues: [1-118] |
1 11 21 31 41 51
| | | | | |
1 MDALTPRDSP KRDDSMATSA ATAASAKPDA LTIGKEGIVH GHIHNYNNLT YIHGHLHHSA 60
61 PVNDSSASAT PAAAAVADAA TSAFASGASH DMGGDCHVNE KCKEYTDCQH FEFLNYHN
|
| Detection Method: |  |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
| MCM Score |
GO Score |
GO Term |
SCOP Match |
SCOP Description | ||
| View | Download | 0.411 | 0.384 | cellular zinc ion homeostasis | b.40.4 | Nucleic acid-binding proteins |
| View | Download | 0.379 | 0.046 | cellular zinc ion homeostasis | a.74.1 | Cyclin-like |
| View | Download | 0.504 | N/A | N/A | b.61.4 | Quinohemoprotein amine dehydrogenase A chain, domain 3 |
| View | Download | 0.502 | N/A | N/A | d.58.9 | RuBisCO, large subunit, small (N-terminal) domain |
| View | Download | 0.446 | N/A | N/A | d.16.1 | FAD-linked reductases, C-terminal domain |
| View | Download | 0.322 | N/A | N/A | d.93.1 | SH2 domain |
| View | Download | 0.308 | N/A | N/A | a.45.1 | Glutathione S-transferase (GST), C-terminal domain |
| View | Download | 0.297 | N/A | N/A | b.60.1 | Lipocalins |
| View | Download | 0.271 | N/A | N/A | b.113.1 | N-terminal domain of MutM-like DNA repair proteins |
| View | Download | 0.267 | N/A | N/A | d.110.4 | SNARE-like |
| View | Download | 0.266 | N/A | N/A | c.49.1 | Pyruvate kinase, C-terminal domain |
| View | Download | 0.262 | N/A | N/A | d.129.1 | TATA-box binding protein-like |
| View | Download | 0.250 | N/A | N/A | d.108.1 | Acyl-CoA N-acyltransferases (Nat) |
| View | Download | 0.247 | N/A | N/A | c.50.1 | Macro domain-like |
| View | Download | 0.246 | N/A | N/A | d.52.7 | Ribosome-binding factor A, RbfA |
| View | Download | 0.243 | N/A | N/A | d.110.4 | SNARE-like |
| View | Download | 0.225 | N/A | N/A | b.71.1 | Glycosyl hydrolase domain |
| View | Download | 0.218 | N/A | N/A | a.4.12 | TrpR-like |
| View | Download | 0.211 | N/A | N/A | b.60.1 | Lipocalins |
| View | Download | 0.204 | N/A | N/A | a.134.1 | Fungal elicitin |
|
Region A: Residues: [119-286] |
1 11 21 31 41 51
| | | | | |
1 NPSLTKYNDT ATYNSNNHSF ANNFHSVASD PTSPQQNSKS DLPRRKDSWF NDDLILLPSS 60
61 KKNKPNPPPG SDDCYCTPKI LEICCDETHP KSEANIKQGE SDQPTKKDIS ENGNDVAIFT 120
121 DVKNDHLMPN FNLHDQYCNS TNHDSHNHNN TVPDSFSQLM SHLSEIDC
|
| Detection Method: | |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
|
Region A: Residues: [287-408] |
1 11 21 31 41 51
| | | | | |
1 DLTCDTPCTA STSATSGHKF VQDHQSSNND DVFHKYCKFC EESTDNQPCS KHMHLESKPP 60
61 QLPPKCSSLR KPTNTLQGTN HAYHEHILNT DMDLKILEDL CNISSLYEVP FGKHINHHDH 120
121 NN
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
SCOP Match |
SCOP Description | ||
| View | Download | 0.344 | a.118.8 | TPR-like |
| View | Download | 0.239 | a.22.1 | Histone-fold |
| View | Download | 0.344 | a.118.8 | TPR-like |
| View | Download | 0.239 | a.22.1 | Histone-fold |
|
Region A: Residues: [409-559] |
1 11 21 31 41 51
| | | | | |
1 AGNGCDGSST GNNENGNQTM NLLLSSINRC NPKNNLNGSN NNTAGATSTD HQHHHHRIQF 60
61 HSHKPNRNNI VNNSGISAAN TTADLTNNDL NDLISREYSY ERFRNQSEPP SLPKVTHQNQ 120
121 KNRRSWPTKD LESTDFSSLE DSLPSSISPP I
|
| Detection Method: | |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
| Term | Confidence | Notes |
| transcription regulator activity | 4.70988788192472 | bayes_pls_golite062009 |
| nucleic acid binding | 4.58713908116892 | bayes_pls_golite062009 |
| DNA binding | 4.56219307357342 | bayes_pls_golite062009 |
| transcription factor activity | 3.50954949535763 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity | 3.22082323675675 | bayes_pls_golite062009 |
| binding | 3.10743787485868 | bayes_pls_golite062009 |
| transcription activator activity | 2.19952417915035 | bayes_pls_golite062009 |
| chromatin binding | 2.18464662431232 | bayes_pls_golite062009 |
| transcription repressor activity | 1.64349785387632 | bayes_pls_golite062009 |
| specific RNA polymerase II transcription factor activity | 1.63161912031789 | bayes_pls_golite062009 |
| sequence-specific DNA binding | 1.42975942698743 | bayes_pls_golite062009 |
| transcription factor binding | 1.39608963544799 | bayes_pls_golite062009 |
| protein binding | 1.00484935878505 | bayes_pls_golite062009 |
| transcription cofactor activity | 0.77874411480713 | bayes_pls_golite062009 |
| cation binding | 0.528413183335504 | bayes_pls_golite062009 |
| metal ion binding | 0.528413183335504 | bayes_pls_golite062009 |
| ion binding | 0.521964257640017 | bayes_pls_golite062009 |
| transition metal ion binding | 0.495045338513967 | bayes_pls_golite062009 |
| catalytic activity | 0.245893663605433 | bayes_pls_golite062009 |
| transcription corepressor activity | 0.10558148421807 | bayes_pls_golite062009 |
|
Region A: Residues: [560-690] |
1 11 21 31 41 51
| | | | | |
1 QTTSTINFNW CFKEEKNNDL KCKWKECPES CSSLFDLQRH LLKDHVSQDF KHPMEPLACN 60
61 WEDCDFLGDD TCSIVNHINC QHGINFDIQF ANPDSFLPGS ISKEKHHLLH CPNPQTHEVS 120
121 KADGAPDMTS A
|
| Detection Method: | |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
| MCM Score |
GO Score |
GO Term |
SCOP Match |
SCOP Description | ||
| View | Download | 0.501 | 0.377 | cellular zinc ion homeostasis | a.45.1 | Glutathione S-transferase (GST), C-terminal domain |
| View | Download | 0.377 | 0.058 | cellular zinc ion homeostasis | a.74.1 | Cyclin-like |
| View | Download | 0.337 | 0.015 | cellular zinc ion homeostasis | a.24.10 | Histidine-containing phosphotransfer domain, HPT domain |
| View | Download | 0.501 | N/A | N/A | a.45.1 | Glutathione S-transferase (GST), C-terminal domain |
| View | Download | 0.466 | N/A | N/A | d.58.41 | SEA domain |
| View | Download | 0.466 | N/A | N/A | d.58.41 | SEA domain |
| View | Download | 0.423 | N/A | N/A | a.45.1 | Glutathione S-transferase (GST), C-terminal domain |
| View | Download | 0.377 | N/A | N/A | a.74.1 | Cyclin-like |
| View | Download | 0.337 | N/A | N/A | a.24.10 | Histidine-containing phosphotransfer domain, HPT domain |
| View | Download | 0.291 | N/A | N/A | c.13.2 | Anti-sigma factor antagonist SpoIIaa |
| View | Download | 0.260 | N/A | N/A | c.24.1 | Methylglyoxal synthase-like |
| View | Download | 0.241 | N/A | N/A | a.26.1 | 4-helical cytokines |
| View | Download | 0.227 | N/A | N/A | d.74.3 | RBP11-like subunits of RNA polymerase |
| View | Download | 0.223 | N/A | N/A | a.7.2 | Enzyme IIa from lactose specific PTS, IIa-lac |
| View | Download | 0.213 | N/A | N/A | a.23.4 | Mitochondrial import receptor subunit Tom20 |
| View | Download | 0.201 | N/A | N/A | a.26.1 | 4-helical cytokines |
|
Region A: Residues: [691-787] |
1 11 21 31 41 51
| | | | | |
1 NDVSNIPPIK QPEQVICQWD GCNKSFSSAQ ELNDHLEAVH LTRGKSEYQC LWHDCHRTFP 60
61 QRQKLIRHLK VHSKYKPYKC KTCKRCFSSE ETLVQHT
|
| Detection Method: | |
| Confidence: | 227.68867 |
| Match: | 2gliA_ |
| Description: | Five-finger GLI1 |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [788-880] |
1 11 21 31 41 51
| | | | | |
1 RTHSGEKPYK CHICNKKFAI SSSLKIHIRT HTGEKPLQCK ICGKRFNESS NLSKHIKTHQ 60
61 KKYKCSDCSK SFDDLGKLNS QKVKCALERK PYL
|
| Detection Method: | |
| Confidence: | 227.68867 |
| Match: | 2gliA_ |
| Description: | Five-finger GLI1 |
| Matching Structure (courtesy of the PDB): |
|
