YRC Public Data Repository - Protein Structure Prediction

Protein:	MTG2
Organism:	Saccharomyces cerevisiae
Length:	499 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MTG2.

Description	E-value	Query Range	Subject Range
MTG2 - Putative GTPase, member of the Obg family; peripheral protein of the mitochondrial inner membrane th...	0.0	[1..499]	[1..499]
OBG_YERPS - GTPase obg OS=Yersinia pseudotuberculosis GN=obg PE=3 SV=1 OBG_YERPB - GTPase Obg OS=Yersinia pseudotuberculosis serotype IB (strain PB1/+) GN=obg PE=3 SV=1 OBG_YERPY - GTPase Obg OS=Yersinia pseudotuberculosis serotype O:3 (strain YPIII) GN=obg PE=3 SV=1 gi\|149288923, gi... - gi\|153997286\|ref\|ZP_02022386.1\| putative GTP-binding protein [Yersinia pestis CA88-4125], gi\|1492889... OBG_YERPP - GTPase Obg OS=Yersinia pestis (strain Pestoides F) GN=obg PE=3 SV=1 gi\|229839162, gi... - gi\|229839162\|ref\|ZP_04459321.1\| GTPase involved in cell partioning and DNA repair [Yersinia pestis b... gi\|229700429, gi... - gi\|229896651\|ref\|ZP_04511818.1\| GTPase involved in cell partioning and DNA repair [Yersinia pestis P... gi\|229899726, gi... - gi\|229899726\|ref\|ZP_04514867.1\| GTPase involved in cell partioning and DNA repair [Yersinia pestis b... OBG_YERPG - GTPase Obg OS=Yersinia pestis bv. Antiqua (strain Angola) GN=obg PE=3 SV=1 OBG_YERP3 - GTPase Obg OS=Yersinia pseudotuberculosis serotype O:1b (strain IP 31758) GN=obg PE=3 SV=1 gi\|165928177, gi... - gi\|165928177\|ref\|ZP_02224009.1\| GTP-binding protein Obg/CgtA [Yersinia pestis biovar Orientalis str.... gi\|166214038, gi... - gi\|166214038\|ref\|ZP_02240073.1\| GTP-binding protein Obg/CgtA [Yersinia pestis biovar Antiqua str. B4... gi\|89104079, gi\|... - gi\|89104079\|ref\|ZP_01176633.1\| COG0536: Predicted GTPase [Yersinia pestis biovar Orientalis str. IP2... gi\|165989718, gi... - gi\|166011334\|ref\|ZP_02232232.1\| GTP-binding protein Obg/CgtA [Yersinia pestis biovar Antiqua str. E1... gi\|167420644, gi... - gi\|167420644\|ref\|ZP_02312397.1\| GTP-binding protein Obg/CgtA [Yersinia pestis biovar Orientalis str.... gi\|167401242, gi... - gi\|167401242\|ref\|ZP_02306742.1\| GTP-binding protein Obg/CgtA [Yersinia pestis biovar Antiqua str. UG... gi\|167470189 - gi\|167470189\|ref\|ZP_02334893.1\| GTP-binding protein Obg/CgtA [Yersinia pestis FV-1] gi\|167057540, gi... - gi\|167423370\|ref\|ZP_02315123.1\| GTP-binding protein Obg/CgtA [Yersinia pestis biovar Mediaevalis str... OBG_YERPE - GTPase Obg OS=Yersinia pestis GN=obg PE=3 SV=1 gi\|45435285, gi\|... - gi\|45440428\|ref\|NP_991967.1\| GTPase ObgE [Yersinia pestis biovar Microtus str. 91001], gi\|45435285\|g... gi\|21957391, gi\|... - gi\|22124589\|ref\|NP_668012.1\| GTPase ObgE [Yersinia pestis KIM], gi\|21957391\|gb\|AAM84263.1\|AE013669_1... gi\|115349134, gi... - gi\|218930523\|ref\|YP_002348398.1\| GTPase ObgE [Yersinia pestis CO92], gi\|16123655\|ref\|NP_406968.1\| pu... OBG_YERPA - GTPase Obg OS=Yersinia pestis bv. Antiqua (strain Antiqua) GN=obg PE=3 SV=1 OBG_YERPS - GTPase Obg OS=Yersinia pseudotuberculosis serotype I (strain IP32953) GN=obg PE=3 SV=1 OBG_YERPN - GTPase Obg OS=Yersinia pestis bv. Antiqua (strain Nepal516) GN=obg PE=3 SV=1	7.0E-67	[194..490]	[10..313]
OBG_PASMU - GTPase obg OS=Pasteurella multocida GN=obg PE=3 SV=1 OBG_PASMU - GTPase Obg OS=Pasteurella multocida (strain Pm70) GN=obg PE=3 SV=1	2.0E-66	[195..498]	[11..319]
OBG_RALSO - GTPase Obg OS=Ralstonia solanacearum (strain GMI1000) GN=obg PE=3 SV=1 OBG_RALSO - GTPase obg OS=Ralstonia solanacearum GN=obg PE=3 SV=1	7.0E-65	[195..496]	[11..318]
YHBZ_ECOLI - Hypothetical GTP-binding protein yhbZ - Escherichia coli EG12795 - GTPase involved in cell partioning and DNA repair / DNA-binding GTPase involved in cell partioning a... gi\|89109946, gi\|... - gi\|89109946\|ref\|AP_003726.1\| GTPase involved in cell partioning and DNA repair [Escherichia coli str... OBG_ECODH - GTPase Obg OS=Escherichia coli (strain K12 / DH10B) GN=obg PE=3 SV=1 gi\|238902285, gi... - gi\|238902285\|ref\|YP_002928081.1\| GTPase involved in cell partioning and DNA repair [Escherichia coli... EG12795 - GTPase involved in cell partioning and DNA repair / DNA-binding GTPase involved in cell partioning a...	8.0E-65	[194..497]	[10..318]
gi\|29139187, gi\|... - gi\|29143552\|ref\|NP_806894.1\| GTPase ObgE [Salmonella enterica subsp. enterica serovar Typhi str. Ty2... gi\|16762063 - gi\|16762063\|ref\|NP_457680.1\| GTPase ObgE [Salmonella enterica subsp. enterica serovar Typhi str. CT1... gi\|213029443 - gi\|213029443\|ref\|ZP_03343890.1\| GTPase ObgE [Salmonella enterica subsp. enterica serovar Typhi str. ... gi\|214000938 - gi\|214000938\|ref\|ZP_03411673.1\| GTPase ObgE [Salmonella enterica subsp. enterica serovar Typhi str. ... gi\|213425421 - gi\|213425421\|ref\|ZP_03358171.1\| GTPase ObgE [Salmonella enterica subsp. enterica serovar Typhi str. ... OBG_SALTI - GTPase Obg OS=Salmonella typhi GN=obg PE=3 SV=1 gi\|213582304 - gi\|213582304\|ref\|ZP_03364130.1\| GTPase ObgE [Salmonella enterica subsp. enterica serovar Typhi str. ... gi\|213609407 - gi\|213609407\|ref\|ZP_03369233.1\| GTPase ObgE [Salmonella enterica subsp. enterica serovar Typhi str. ... gi\|213646991 - gi\|213646991\|ref\|ZP_03377044.1\| GTPase ObgE [Salmonella enterica subsp. enterica serovar Typhi str. ...	1.0E-64	[194..490]	[10..313]
OBG_AQUAE - GTPase Obg OS=Aquifex aeolicus (strain VF5) GN=obg PE=3 SV=1 OBG_AQUAE - GTPase obg OS=Aquifex aeolicus GN=obg PE=3 SV=1	2.0E-64	[194..498]	[11..318]
gi\|168819631, gi... - gi\|205343332\|gb\|EDZ30096.1\| GTP-binding protein Obg/CgtA [Salmonella enterica subsp. enterica serova... OBG_SALNS - GTPase Obg OS=Salmonella newport (strain SL254) GN=obg PE=3 SV=1 gi\|168262688, gi... - gi\|205348439\|gb\|EDZ35070.1\| GTP-binding protein Obg/CgtA [Salmonella enterica subsp. enterica serova... gi\|168463475, gi... - gi\|195633344\|gb\|EDX51758.1\| GTP-binding protein Obg/CgtA [Salmonella enterica subsp. enterica serova... gi\|197289088, gi... - gi\|197289088\|gb\|EDY28457.1\| GTP-binding protein Obg/CgtA [Salmonella enterica subsp. enterica serova... gi\|205337846, gi... - gi\|205337846\|gb\|EDZ24610.1\| GTP-binding protein Obg/CgtA [Salmonella enterica subsp. enterica serova... gi\|205323187, gi... - gi\|205323187\|gb\|EDZ11026.1\| GTP-binding protein Obg/CgtA [Salmonella enterica subsp. enterica serova... gi\|168231911, gi... - gi\|205333853\|gb\|EDZ20617.1\| GTP-binding protein Obg/CgtA [Salmonella enterica subsp. enterica serova... OBG_SALPB - GTPase obg OS=Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7) GN=obg PE=3 SV=1 OBG_SALPB - GTPase Obg OS=Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7) GN=obg PE=3 SV=1 OBG_SALPC - GTPase Obg OS=Salmonella paratyphi C (strain RKS4594) GN=obg PE=3 SV=1 gi\|204931185, gi... - gi\|204931185\|ref\|ZP_03221979.1\| GTP-binding protein Obg/CgtA [Salmonella enterica subsp. enterica se... OBG_SALEP - GTPase Obg OS=Salmonella enteritidis PT4 (strain P125109) GN=obg PE=3 SV=1 OBG_SALDC - GTPase Obg OS=Salmonella dublin (strain CT_02021853) GN=obg PE=3 SV=1 gi\|200387836, gi... - gi\|200387836\|ref\|ZP_03214448.1\| GTP-binding protein Obg/CgtA [Salmonella enterica subsp. enterica se... gi\|197265678, gi... - gi\|197265678\|ref\|ZP_03165752.1\| GTP-binding protein Obg/CgtA [Salmonella enterica subsp. enterica se... OBG_SALPK - GTPase Obg OS=Salmonella paratyphi A (strain AKU_12601) GN=obg PE=3 SV=1 OBG_SALSV - GTPase Obg OS=Salmonella schwarzengrund (strain CVM19633) GN=obg PE=3 SV=1 OBG_SALA4 - GTPase Obg OS=Salmonella agona (strain SL483) GN=obg PE=3 SV=1 OBG_SALHS - GTPase Obg OS=Salmonella heidelberg (strain SL476) GN=obg PE=3 SV=1 gi\|194455340, gi... - gi\|194468976\|ref\|ZP_03074960.1\| GTP-binding protein Obg/CgtA [Salmonella enterica subsp. enterica se... OBG_SALPA - GTPase Obg OS=Salmonella paratyphi A (strain ATCC 9150 / SARB42) GN=obg PE=3 SV=1 OBG_SALCH - GTPase Obg OS=Salmonella choleraesuis (strain SC-B67) GN=obg PE=3 SV=1 OBG_SALTY - GTPase Obg OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) GN=obg PE=1 SV=1 lcl\|NC_016856.1_... - [gene=obgE] [protein=GTPase ObgE] [protein_id=YP_005239481.1] [location=complement(3484114..3485286)... OBG_SALPA - GTPase obg OS=Salmonella paratyphi A GN=obg PE=3 SV=1 OBG_SALTY - GTPase obg OS=Salmonella typhimurium GN=obg PE=1 SV=1 gi\|238910095 - gi\|238910095\|ref\|ZP_04653932.1\| GTPase ObgE [Salmonella enterica subsp. enterica serovar Tennessee s... OBG_SALCH - GTPase obg OS=Salmonella choleraesuis GN=obg PE=3 SV=1	2.0E-64	[194..490]	[10..313]
gi\|188491854, gi... - gi\|75510980\|ref\|ZP_00733739.1\| COG0536: Predicted GTPase [Escherichia coli 53638], gi\|188491854\|ref\|... gi\|191174476, gi... - gi\|75236237\|ref\|ZP_00720347.1\| COG0536: Predicted GTPase [Escherichia coli F11], gi\|191174476\|ref\|ZP... gi\|189374127, gi... - gi\|189374127\|gb\|EDU92543.1\| GTP-binding protein Obg/CgtA [Escherichia coli O157:H7 str. EC869], gi\|1... gi\|13363535, gi\|... - gi\|15833316\|ref\|NP_312089.1\| GTPase ObgE [Escherichia coli O157:H7 str. Sakai], gi\|13363535\|dbj\|BAB3... gi\|168781327, gi... - gi\|189001085\|gb\|EDU70071.1\| GTP-binding protein Obg/CgtA [Escherichia coli O157:H7 str. EC4076], gi\|... OBG_ECOL5 - GTPase Obg OS=Escherichia coli O6:K15:H31 (strain 536 / UPEC) GN=obg PE=3 SV=1 gi\|208727362, gi... - gi\|208807561\|ref\|ZP_03249898.1\| GTP-binding protein Obg/CgtA [Escherichia coli O157:H7 str. EC4206],... gi\|195938402 - gi\|195938402\|ref\|ZP_03083784.1\| GTPase ObgE [Escherichia coli O157:H7 str. EC4024] gi\|208742116, gi... - gi\|208821993\|ref\|ZP_03262313.1\| GTP-binding protein Obg/CgtA [Escherichia coli O157:H7 str. EC4042],... gi\|208735131, gi... - gi\|208813854\|ref\|ZP_03255183.1\| GTP-binding protein Obg/CgtA [Escherichia coli O157:H7 str. EC4045],... gi\|217320124, gi... - gi\|217327757\|ref\|ZP_03443840.1\| GTP-binding protein Obg/CgtA [Escherichia coli O157:H7 str. TW14588]... OBG_ECO5E - GTPase Obg OS=Escherichia coli O157:H7 (strain EC4115 / EHEC) GN=obg PE=3 SV=1 gi\|168769039, gi... - gi\|189361859\|gb\|EDU80278.1\| GTP-binding protein Obg/CgtA [Escherichia coli O157:H7 str. EC4486], gi\|... gi\|189358740, gi... - gi\|189358740\|gb\|EDU77159.1\| GTP-binding protein Obg/CgtA [Escherichia coli O157:H7 str. EC4401], gi\|... gi\|209758208, gi... - pir\|\|A85982 probable GTP-binding factor yhbZ [imported] - Escherichia coli (strain O157:H7, substrai... OBG_ECO57 - GTPase Obg OS=Escherichia coli O157:H7 GN=obg PE=3 SV=1 OBG_ECOL6 - GTPase Obg OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) GN=obg PE=3 SV=1 OBG_ECO45 - GTPase Obg OS=Escherichia coli O45:K1 (strain S88 / ExPEC) GN=obg PE=3 SV=1 gi\|12517798, gi\|... - gi\|15803723\|ref\|NP_289757.1\| GTPase ObgE [Escherichia coli O157:H7 EDL933], gi\|12517798\|gb\|AAG58317.... gi\|227887904, gi... - gi\|227887904\|ref\|ZP_04005709.1\| GTP-binding protein [Escherichia coli 83972], gi\|227835300\|gb\|EEJ457... OBG_ECOK1 - GTPase Obg OS=Escherichia coli O1:K1 / APEC GN=obg PE=3 SV=1 gi\|226899105, gi... - gi\|237706065\|ref\|ZP_04536546.1\| GTPase ObgE [Escherichia sp. 3_2_53FAA], gi\|226899105\|gb\|EEH85364.1\|... gi\|254038348, gi... - gi\|254038348\|ref\|ZP_04872406.1\| GTPase ObgE [Escherichia sp. 1_1_43], gi\|226839972\|gb\|EEH71993.1\| GT... gi\|254795132, gi... - gi\|254795132\|ref\|YP_003079969.1\| GTPase involved in cell partioning and DNA repair [Escherichia coli... OBG_ECOL6 - GTPase obg OS=Escherichia coli O6 GN=obg PE=3 SV=1	2.0E-64	[194..497]	[10..318]
gi\|25295785 - pir\|\|C97863 GTP-binding protein [imported] - Rickettsia conorii (strain Malish 7) gi\|15620447, gi\|... - gi\|15893230\|ref\|NP_360944.1\| GTP-binding protein [Rickettsia conorii str. Malish 7], gi\|15620447\|gb\|...	2.0E-64	[196..497]	[44..344]

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Predicted Domain #1

Region A:
Residues: [1-324]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSIAWSSVFK RELRLERFLP RVYSTKVPDN APRAADNEQW LETLRPITHP EQKKSDHDVS  60
   61 YTRHINVPLG EVTSVNYLQR YNKHKHSQGN FVDVRIVKCK SGAGGSGAVS FFRDAGRSIG 120
  121 PPDGGDGGAG GSVYIQAVAG LGSLAKMKTT YTAEDGEAGA ARQLDGMRGR DVLIQVPVGT 180
  181 VVKWCLPPQK VRELVEREMR KDNNATLRSI LGSTAVNLSV SSGSHRKKIQ LYRHEMAESW 240
  241 LFKDKAKEYH ENKDWFKDLH KKMEAYDHSL EQSELFNDQF PLAGLDLNQP MTKPVCLLKG 300
  301 GQGGLGNMHF LTNLIRNPRF SKPG

[Run NCBI BLAST on this sequence.]

Detection Method:	Pfam
Confidence:	108.29243
Match:	PF01018
Description:	GTP1/OBG

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [325-499]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RNGLEQHFLF ELKSIADLGL IGLPNAGKST ILNKISNAKP KIGHWQFTTL SPTIGTVSLG  60
   61 FGQDVFTVAD IPGIIQGASL DKGMGLEFLR HIERSNGWVF VLDLSNKNPL NDLQLLIEEV 120
  121 GTLEKVKTKN ILIVCNKVDI DAEKSESFAK YLQVEKFSKS QEWDCVPISA LREKT

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	62.69897
Match:	1ksgA_
Description:	ADP-ribosylation factor
Matching Structure (courtesy of the PDB):

Predicted Domain #3

Region A:
Residues: [128-184]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GAGGSVYIQA VAGLGSLAKM KTTYTAEDGE AGAARQLDGM RGRDVLIQVP VGTVVKW

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	13.045757
Match:	1xzpB
Description:	Structure of the GTP-binding protein TrmE from Thermotoga maritima
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	1.65079399897053	bayes_pls_golite062009
binding	0.604868700215668	bayes_pls_golite062009
aminomethyltransferase activity	0.573831999310668	bayes_pls_golite062009
transferase activity	0.217873555384951	bayes_pls_golite062009

Predicted Domain #4

Region A:
Residues: [185-499]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 CLPPQKVREL VEREMRKDNN ATLRSILGST AVNLSVSSGS HRKKIQLYRH EMAESWLFKD  60
   61 KAKEYHENKD WFKDLHKKME AYDHSLEQSE LFNDQFPLAG LDLNQPMTKP VCLLKGGQGG 120
  121 LGNMHFLTNL IRNPRFSKPG RNGLEQHFLF ELKSIADLGL IGLPNAGKST ILNKISNAKP 180
  181 KIGHWQFTTL SPTIGTVSLG FGQDVFTVAD IPGIIQGASL DKGMGLEFLR HIERSNGWVF 240
  241 VLDLSNKNPL NDLQLLIEEV GTLEKVKTKN ILIVCNKVDI DAEKSESFAK YLQVEKFSKS 300
  301 QEWDCVPISA LREKT

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	64.0
Match:	1lnzA
Description:	Obg GTP-binding protein N-terminal domain; Obg GTP-binding protein C-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	1.62320027057768	bayes_pls_golite062009
catalytic activity	1.00104173493322	bayes_pls_golite062009
nucleic acid binding	0.913322399315129	bayes_pls_golite062009
GTPase activity	0.87408935068982	bayes_pls_golite062009
structural constituent of ribosome	0.738234102557832	bayes_pls_golite062009
purine nucleotide binding	0.569910969126728	bayes_pls_golite062009
purine ribonucleotide binding	0.568840867400671	bayes_pls_golite062009
ribonucleotide binding	0.568779924702229	bayes_pls_golite062009
nucleotide binding	0.564275755355315	bayes_pls_golite062009
hydrolase activity	0.441914529351098	bayes_pls_golite062009
DNA binding	0.376487324624615	bayes_pls_golite062009
translation regulator activity	0.29096092258568	bayes_pls_golite062009
translation factor activity, nucleic acid binding	0.274994961137851	bayes_pls_golite062009
ATP binding	0.1860481660648	bayes_pls_golite062009
adenyl ribonucleotide binding	0.152859582615242	bayes_pls_golite062009
transcription regulator activity	0.150159515184919	bayes_pls_golite062009
adenyl nucleotide binding	0.138615225841109	bayes_pls_golite062009
nucleoside-triphosphatase activity	0.0880086189831292	bayes_pls_golite062009
pyrophosphatase activity	0.0746809525189132	bayes_pls_golite062009
structural molecule activity	0.0558641287316701	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides	0.0557582578674931	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	0.0529869469040288	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions:

Predicted functions: