






| Protein: | CCH1 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 2039 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CCH1.
| Description | E-value | Query Range |
Subject Range |
|
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0.0 | [422..1969] | [108..1677] |
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0.0 | [422..1950] | [101..1643] |
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0.0 | [422..1906] | [101..1587] |
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0.0 | [709..1935] | [669..1930] |
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0.0 | [422..1969] | [35..1582] |
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0.0 | [554..1969] | [1..1407] |
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Region A: Residues: [1-232] |
1 11 21 31 41 51
| | | | | |
1 MQGRKRTLTE PFEPNTNPFG DNAAVMTENV EDNSETDGNR LESKPQALVP PALNIVPPES 60
61 SIHSTEEKKG DEYNGNDKDS SLISNIFRTR VGRSSHENLS RPKLSLKTAS FGAAESSRRN 120
121 VSPSTKSAKS SSQYIDLNDE RLRRRSFSSY SRSSSRRVSN SPSSTDRPPR SAKVLSLIAA 180
181 DDMDDFEDLQ KGFKSAIDEE GLTWLPQLKS EKSRPVSDVG EDRGEGEQES IP
|
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [233-365] |
1 11 21 31 41 51
| | | | | |
1 DVHTPNVGAS ATPGSIHLTP EPAQNGSVSE GLEGSINNSR KKPSPKFFHH LSPQKEDKDQ 60
61 TEVIEYAEDI LDFETLQRKL ESRPFVLYGH SLGVFSPTNP LRIKIARFLL HRRYSLLYNT 120
121 LLTFYAILLA IRT
|
| Detection Method: | |
| Confidence: | 19.0 |
| Match: | 1exbE_ |
| Description: | KV1.1 |
Matching Structure (courtesy of the PDB):![]() |
|
|
Region A: Residues: [366-426] |
1 11 21 31 41 51
| | | | | |
1 YNPHNVVFLY RFSNWTDYFI FILSACFTGN DIAKIIAFGF WDDSEMFKAY GREYKSILQR 60
61 S
|
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
| MCM Score |
GO Score |
GO Term |
SCOP Match |
SCOP Description | ||
| View | Download | 0.402 | 0.816 | calcium ion transport | a.4.1 | Homeodomain-like |
|
Region A: Residues: [427-611] |
1 11 21 31 41 51
| | | | | |
1 GIMKLYIYLR EKYGRKLIDF IIPFRIISPG EETKYQRSSL STSLTKPYGA KENQRPFGTP 60
61 RAFARSSWNR IDLVSSVSFW LGMFLSIKSY DTKTGIRIFK PLAILRILRL VNVDTGMPSI 120
121 LRGLKYGIPQ LVNVSSMLVY FWIFFGILGV QIFQGSFRRQ CVWFNPEDPT DTYQYDMQFC 180
181 GGYLD
|
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [612-1110] |
1 11 21 31 41 51
| | | | | |
1 PVTKRKQNYI YEDGSEGSVS KGFLCPQYSK CVSNANPYNG RISFDNIVNS MELVFVIMSA 60
61 NTFTDLMYYT MDSDEMAACL FFIVCIFVLT IWLLNLLIAV LVSSFEIANE EYKKKKFIYG 120
121 SRKTGYVARI VTGYWKYFKL KANQTKFPNW SQKGLAIYSH VEFIFVILII CDIGMRASVK 180
181 VSTSANCNNI LLKTDRGISI VLFIESLARL VLYLPNMWKF LTKPSYVYDF IISIITLVIS 240
241 CLAVEGVLGH MYAWLSIFHI SRFYRVIISF NLTKKLWKQI LSNGVMIWNL SSFYFFFTFL 300
301 VAIIMAVYFE GVIPPEEMAD QPFGMYSLPN SFLSLFIIGS TENWTDILYA LQKHSPNISS 360
361 TFFCSVFFII WFLLSNSVIL NIFIALISES MEVKEEEKRP QQIKHYLKFV YPQKIQEYTH 420
421 ASLVARIRKK FFGGHRNEDT RDFKQFLMRG TAIMNIAQNM GELADEFKEP PSENLFKKGL 480
481 SKLTIGVPSL KRLRMFANN
|
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [1111-1197] |
1 11 21 31 41 51
| | | | | |
1 PFYKNSDVVF TETNDINGRT YILELNEYED EKLDYLKKYP LFNYSYYFFS PQHRFRRFCQ 60
61 RLVPPSTGKR TDGSRFFEDS TDLYNKR
|
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
| Term | Confidence | Notes |
| metal ion transmembrane transporter activity | 4.7372448658795 | bayes_pls_golite062009 |
| voltage-gated cation channel activity | 4.63984862452408 | bayes_pls_golite062009 |
| cation transmembrane transporter activity | 4.6123766644348 | bayes_pls_golite062009 |
| voltage-gated potassium channel activity | 4.56176308768245 | bayes_pls_golite062009 |
| ion transmembrane transporter activity | 4.53708718755887 | bayes_pls_golite062009 |
| potassium channel activity | 4.51985608289081 | bayes_pls_golite062009 |
| voltage-gated ion channel activity | 4.5171803357978 | bayes_pls_golite062009 |
| voltage-gated channel activity | 4.51256290813453 | bayes_pls_golite062009 |
| cation channel activity | 4.45938408950249 | bayes_pls_golite062009 |
| substrate-specific transmembrane transporter activity | 4.18703661144599 | bayes_pls_golite062009 |
| gated channel activity | 3.79587174965364 | bayes_pls_golite062009 |
| substrate-specific channel activity | 3.72917222310854 | bayes_pls_golite062009 |
| ion channel activity | 3.48521592747971 | bayes_pls_golite062009 |
| passive transmembrane transporter activity | 3.39410147300457 | bayes_pls_golite062009 |
| channel activity | 3.39410147300457 | bayes_pls_golite062009 |
| transporter activity | 2.77619896060397 | bayes_pls_golite062009 |
| transmembrane transporter activity | 2.65613366364107 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 2.3511225030312 | bayes_pls_golite062009 |
| inward rectifier potassium channel activity | 2.22500563098935 | bayes_pls_golite062009 |
| ligand-gated channel activity | 1.95018194128504 | bayes_pls_golite062009 |
| ligand-gated ion channel activity | 1.95018194128504 | bayes_pls_golite062009 |
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Region A: Residues: [1198-1330] |
1 11 21 31 41 51
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1 SYFHHIERDV FVFIFALATI LLIVCSCYVT PLYRMHHKMG TWNWSSALDC AFIGAFSIEF 60
61 IVKTVADGFI YSPNAYLRNP WNFIDFCVLI SMWINLIAYL KNNGNLSRIF KGLTALRALR 120
121 CLTISNTARQ TFN
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Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
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Region A: Residues: [1331-1437] |
1 11 21 31 41 51
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1 LVMFDGLNKI FEAGLISLSL LFPFTVWGLS IFKGRLGTCN DGSLGRADCY NEYSNSVFQW 60
61 DIMSPRVYQQ PYLHLDSFAS AFSSLYQIIS LEGWVDLLEN MMNSSGI
|
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
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Region A: Residues: [1438-1528] |
1 11 21 31 41 51
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1 GTPATVMGSA GNALFLVLFN FLSMVFILNL FVSFIVNNQA RTTGSAYFTI EEKAWLESQK 60
61 LLSQAKPKAI PNLIELSRVR QFFYQLAVEK K
|
| Detection Method: | |
| Confidence: | 3.522879 |
| Match: | 1byyA_ |
| Description: | Sodium channel IIA |
Matching Structure (courtesy of the PDB):![]() |
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Region A: Residues: [1529-1761] |
1 11 21 31 41 51
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1 NFYYASFLQV VLYLHIIMLL SRSYNPGNLI GYQGVYFMFS TSVFLIQEAL HMCGEGPRLY 60
61 FRQKWNSIRL SIIIIAFIMN AVAFHVPASH YWFHNIKGFF LLVIFLFIIP QNDTLTELLE 120
121 TAMASLPPIL SLTYTWGVLF LVYAIALNQI FGLTRLGSNT TDNINFRTVI KSMIVLFRCS 180
181 FGEGWNYIMA DLTVSEPYCS SDDNSTYTDC GSETYAYLLL MSWNIISMYI FVN
|
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [1762-1891] |
1 11 21 31 41 51
| | | | | |
1 MFVSLIIGNF SYVYRSGGSR SGINRSEIKK YIEAWSKFDT DGTGELELSY LPRIMHSFDG 60
61 PLSFKIWEGR LTIKSLVENY MEVNPDDPYD VKIDLIGLNK ELNTIDKAKI IQRKLQYRRF 120
121 VQSIHYTNAY
|
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
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Region A: Residues: [1892-2039] |
1 11 21 31 41 51
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1 NGCIRFSDLL LQIPLYTAYS ARECLGIDQY VHHLYILGKV DKYLENQRNF DVLEMVVTRW 60
61 KFHCRMKRTI EPEWDVKDPT VSSHISNINV NLEPAPGILE REPIATPRMD YGVNNFMWSP 120
121 RMNQDSTMEP PEEPIDNNDD SANDLIDR
|
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.