| Protein: | CCH1 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 2039 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CCH1.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [422..1969] | [108..1677] |
|
|
0.0 | [422..1950] | [101..1643] |
|
|
0.0 | [422..1906] | [101..1587] |
|
|
0.0 | [709..1935] | [669..1930] |
|
|
0.0 | [422..1969] | [35..1582] |
|
|
0.0 | [554..1969] | [1..1407] |
|
Region A: Residues: [1-232] |
1 11 21 31 41 51
| | | | | |
1 MQGRKRTLTE PFEPNTNPFG DNAAVMTENV EDNSETDGNR LESKPQALVP PALNIVPPES 60
61 SIHSTEEKKG DEYNGNDKDS SLISNIFRTR VGRSSHENLS RPKLSLKTAS FGAAESSRRN 120
121 VSPSTKSAKS SSQYIDLNDE RLRRRSFSSY SRSSSRRVSN SPSSTDRPPR SAKVLSLIAA 180
181 DDMDDFEDLQ KGFKSAIDEE GLTWLPQLKS EKSRPVSDVG EDRGEGEQES IP
|
| Detection Method: |  |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
|
Region A: Residues: [233-365] |
1 11 21 31 41 51
| | | | | |
1 DVHTPNVGAS ATPGSIHLTP EPAQNGSVSE GLEGSINNSR KKPSPKFFHH LSPQKEDKDQ 60
61 TEVIEYAEDI LDFETLQRKL ESRPFVLYGH SLGVFSPTNP LRIKIARFLL HRRYSLLYNT 120
121 LLTFYAILLA IRT
|
| Detection Method: | |
| Confidence: | 19.0 |
| Match: | 1exbE_ |
| Description: | KV1.1 |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [366-426] |
1 11 21 31 41 51
| | | | | |
1 YNPHNVVFLY RFSNWTDYFI FILSACFTGN DIAKIIAFGF WDDSEMFKAY GREYKSILQR 60
61 S
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
GO Score |
GO Term |
SCOP Match |
SCOP Description | ||
| View | Download | 0.402 | 0.816 | calcium ion transport | a.4.1 | Homeodomain-like |
| View | Download | 0.450 | 0.816 | calcium ion transport | a.8.1 | Bacterial immunoglobulin/albumin-binding domains |
| View | Download | 0.445 | 0.816 | calcium ion transport | a.159.1 | Protein serine/threonine phosphatase 2C, C-terminal domain |
| View | Download | 0.416 | 0.816 | calcium ion transport | a.23.5 | Hemolysin expression modulating protein HHA |
| View | Download | 0.537 | 0.816 | calcium ion transport | a.76.1 | Iron-dependent represor protein, dimerization domain |
| View | Download | 0.328 | 0.816 | calcium ion transport | a.5.2 | UBA-like |
| View | Download | 0.318 | 0.816 | calcium ion transport | a.8.1 | Bacterial immunoglobulin/albumin-binding domains |
| View | Download | 0.309 | 0.816 | calcium ion transport | a.4.1 | Homeodomain-like |
| View | Download | 0.303 | 0.816 | calcium ion transport | a.46.2 | Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain |
| View | Download | 0.303 | 0.816 | calcium ion transport | a.101.1 | Uteroglobin-like |
| View | Download | 0.302 | 0.816 | calcium ion transport | a.44.1 | Disulphide-bond formation facilitator (DSBA), insertion domain |
| View | Download | 0.302 | 0.816 | calcium ion transport | a.5.1 | DNA helicase RuvA subunit, C-terminal domain |
| View | Download | 0.292 | 0.816 | calcium ion transport | d.45.1 | ClpS-like |
| View | Download | 0.290 | 0.816 | calcium ion transport | a.48.3 | Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 |
| View | Download | 0.287 | 0.816 | calcium ion transport | a.77.1 | DEATH domain |
| View | Download | 0.267 | 0.816 | calcium ion transport | d.15.1 | Ubiquitin-like |
| View | Download | 0.256 | 0.816 | calcium ion transport | a.157.1 | Skp1 dimerisation domain-like |
| View | Download | 0.238 | 0.816 | calcium ion transport | a.28.3 | Retrovirus capsid protein C-terminal domain |
| View | Download | 0.237 | 0.816 | calcium ion transport | a.37.1 | A DNA-binding domain in eukaryotic transcription factors |
| View | Download | 0.228 | 0.816 | calcium ion transport | a.60.5 | Barrier-to-autointegration factor, BAF |
| View | Download | 0.225 | 0.816 | calcium ion transport | a.4.1 | Homeodomain-like |
| View | Download | 0.224 | 0.816 | calcium ion transport | a.159.2 | FF domain |
| View | Download | 0.218 | 0.816 | calcium ion transport | g.34.1 | HIV-1 VPU cytoplasmic domain |
| View | Download | 0.216 | 0.816 | calcium ion transport | a.138.1 | Multiheme cytochromes |
| View | Download | 0.204 | 0.816 | calcium ion transport | d.15.1 | Ubiquitin-like |
|
Region A: Residues: [427-611] |
1 11 21 31 41 51
| | | | | |
1 GIMKLYIYLR EKYGRKLIDF IIPFRIISPG EETKYQRSSL STSLTKPYGA KENQRPFGTP 60
61 RAFARSSWNR IDLVSSVSFW LGMFLSIKSY DTKTGIRIFK PLAILRILRL VNVDTGMPSI 120
121 LRGLKYGIPQ LVNVSSMLVY FWIFFGILGV QIFQGSFRRQ CVWFNPEDPT DTYQYDMQFC 180
181 GGYLD
|
| Detection Method: | |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
|
Region A: Residues: [612-1110] |
1 11 21 31 41 51
| | | | | |
1 PVTKRKQNYI YEDGSEGSVS KGFLCPQYSK CVSNANPYNG RISFDNIVNS MELVFVIMSA 60
61 NTFTDLMYYT MDSDEMAACL FFIVCIFVLT IWLLNLLIAV LVSSFEIANE EYKKKKFIYG 120
121 SRKTGYVARI VTGYWKYFKL KANQTKFPNW SQKGLAIYSH VEFIFVILII CDIGMRASVK 180
181 VSTSANCNNI LLKTDRGISI VLFIESLARL VLYLPNMWKF LTKPSYVYDF IISIITLVIS 240
241 CLAVEGVLGH MYAWLSIFHI SRFYRVIISF NLTKKLWKQI LSNGVMIWNL SSFYFFFTFL 300
301 VAIIMAVYFE GVIPPEEMAD QPFGMYSLPN SFLSLFIIGS TENWTDILYA LQKHSPNISS 360
361 TFFCSVFFII WFLLSNSVIL NIFIALISES MEVKEEEKRP QQIKHYLKFV YPQKIQEYTH 420
421 ASLVARIRKK FFGGHRNEDT RDFKQFLMRG TAIMNIAQNM GELADEFKEP PSENLFKKGL 480
481 SKLTIGVPSL KRLRMFANN
|
| Detection Method: | |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
| MCM Score |
GO Score |
GO Term |
SCOP Match |
SCOP Description | ||
| View | Download | 0.623 | N/A | N/A | c.47.1 | Thioredoxin-like |
| View | Download | 0.517 | N/A | N/A | c.51.1 | Anticodon-binding domain of Class II aaRS |
| View | Download | 0.482 | N/A | N/A | c.102.1 | Cell-division inhibitor MinC, N-terminal domain |
| View | Download | 0.482 | N/A | N/A | a.23.4 | Mitochondrial import receptor subunit Tom20 |
| View | Download | 0.481 | N/A | N/A | c.102.1 | Cell-division inhibitor MinC, N-terminal domain |
|
Region A: Residues: [1111-1197] |
1 11 21 31 41 51
| | | | | |
1 PFYKNSDVVF TETNDINGRT YILELNEYED EKLDYLKKYP LFNYSYYFFS PQHRFRRFCQ 60
61 RLVPPSTGKR TDGSRFFEDS TDLYNKR
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
SCOP Match |
SCOP Description | ||
| View | Download | 0.623 | c.47.1 | Thioredoxin-like |
| View | Download | 0.474 | d.58.7 | RNA-binding domain, RBD |
| View | Download | 0.482 | a.23.4 | Mitochondrial import receptor subunit Tom20 |
| View | Download | 0.481 | c.102.1 | Cell-division inhibitor MinC, N-terminal domain |
| View | Download | 0.454 | c.47.1 | Thioredoxin-like |
| View | Download | 0.423 | c.47.1 | Thioredoxin-like |
| View | Download | 0.413 | c.110.1 | D-Tyr tRNAtyr deacylase, DTD |
| View | Download | 0.401 | d.80.1 | Tautomerase/MIF |
| View | Download | 0.392 | c.30.1 | PreATP-grasp domain |
| View | Download | 0.365 | d.88.1 | SRF-like |
| View | Download | 0.365 | d.58.44 | Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains |
| View | Download | 0.349 | d.58.18 | Regulatory domain in the aminoacid metabolism |
| View | Download | 0.345 | b.36.1 | PDZ domain-like |
| View | Download | 0.333 | d.109.1 | Actin depolymerizing proteins |
| View | Download | 0.328 | c.58.1 | Aminoacid dehydrogenase-like, N-terminal domain |
| View | Download | 0.321 | d.13.1 | HIT-like |
| View | Download | 0.308 | d.52.1 | Alpha-lytic protease prodomain |
| View | Download | 0.308 | d.16.1 | FAD-linked reductases, C-terminal domain |
| View | Download | 0.304 | c.58.1 | Aminoacid dehydrogenase-like, N-terminal domain |
| View | Download | 0.278 | d.52.2 | GMP synthetase C-terminal dimerisation domain |
| View | Download | 0.278 | d.14.1 | Ribosomal protein S5 domain 2-like |
| View | Download | 0.264 | c.51.1 | Anticodon-binding domain of Class II aaRS |
| View | Download | 0.262 | c.51.1 | Anticodon-binding domain of Class II aaRS |
| View | Download | 0.262 | a.24.15 | FAD-dependent thiol oxidase |
| View | Download | 0.251 | d.109.1 | Actin depolymerizing proteins |
| View | Download | 0.250 | d.26.1 | FKBP-like |
| View | Download | 0.229 | d.79.1 | YjgF-like |
| View | Download | 0.228 | d.65.1 | Hedgehog/DD-pepidase |
| View | Download | 0.226 | d.13.1 | HIT-like |
| View | Download | 0.222 | c.47.1 | Thioredoxin-like |
| View | Download | 0.215 | c.50.1 | Macro domain-like |
| View | Download | 0.211 | c.47.1 | Thioredoxin-like |
| View | Download | 0.209 | d.52.3 | Prokaryotic type KH domain (KH-domain type II) |
| View | Download | 0.209 | d.109.2 | C-terminal, gelsolin-like domain of Sec23/24 |
| View | Download | 0.207 | d.14.1 | Ribosomal protein S5 domain 2-like |
| View | Download | 0.207 | c.37.1 | P-loop containing nucleoside triphosphate hydrolases |
| View | Download | 0.206 | d.134.1 | Sulfite reductase hemoprotein (SiRHP), domains 2 and 4 |
| View | Download | 0.205 | c.13.2 | Anti-sigma factor antagonist SpoIIaa |
| Term | Confidence | Notes |
| metal ion transmembrane transporter activity | 4.7372448658795 | bayes_pls_golite062009 |
| voltage-gated cation channel activity | 4.63984862452408 | bayes_pls_golite062009 |
| cation transmembrane transporter activity | 4.6123766644348 | bayes_pls_golite062009 |
| voltage-gated potassium channel activity | 4.56176308768245 | bayes_pls_golite062009 |
| ion transmembrane transporter activity | 4.53708718755887 | bayes_pls_golite062009 |
| potassium channel activity | 4.51985608289081 | bayes_pls_golite062009 |
| voltage-gated ion channel activity | 4.5171803357978 | bayes_pls_golite062009 |
| voltage-gated channel activity | 4.51256290813453 | bayes_pls_golite062009 |
| cation channel activity | 4.45938408950249 | bayes_pls_golite062009 |
| substrate-specific transmembrane transporter activity | 4.18703661144599 | bayes_pls_golite062009 |
| gated channel activity | 3.79587174965364 | bayes_pls_golite062009 |
| substrate-specific channel activity | 3.72917222310854 | bayes_pls_golite062009 |
| ion channel activity | 3.48521592747971 | bayes_pls_golite062009 |
| passive transmembrane transporter activity | 3.39410147300457 | bayes_pls_golite062009 |
| channel activity | 3.39410147300457 | bayes_pls_golite062009 |
| transporter activity | 2.77619896060397 | bayes_pls_golite062009 |
| transmembrane transporter activity | 2.65613366364107 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 2.3511225030312 | bayes_pls_golite062009 |
| inward rectifier potassium channel activity | 2.22500563098935 | bayes_pls_golite062009 |
| ligand-gated channel activity | 1.95018194128504 | bayes_pls_golite062009 |
| ligand-gated ion channel activity | 1.95018194128504 | bayes_pls_golite062009 |
|
Region A: Residues: [1198-1330] |
1 11 21 31 41 51
| | | | | |
1 SYFHHIERDV FVFIFALATI LLIVCSCYVT PLYRMHHKMG TWNWSSALDC AFIGAFSIEF 60
61 IVKTVADGFI YSPNAYLRNP WNFIDFCVLI SMWINLIAYL KNNGNLSRIF KGLTALRALR 120
121 CLTISNTARQ TFN
|
| Detection Method: | |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
|
Region A: Residues: [1331-1437] |
1 11 21 31 41 51
| | | | | |
1 LVMFDGLNKI FEAGLISLSL LFPFTVWGLS IFKGRLGTCN DGSLGRADCY NEYSNSVFQW 60
61 DIMSPRVYQQ PYLHLDSFAS AFSSLYQIIS LEGWVDLLEN MMNSSGI
|
| Detection Method: | |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
| MCM Score |
GO Score |
GO Term |
SCOP Match |
SCOP Description | ||
| View | Download | 0.384 | 0.305 | calcium channel activity | a.1.1 | Globin-like |
| View | Download | 0.604 | 0.176 | calcium channel activity | a.118.1 | ARM repeat |
| View | Download | 0.515 | 0.029 | calcium channel activity | a.29.2 | Bromodomain |
| View | Download | 0.376 | 0.017 | calcium channel activity | a.24.16 | Nucleotidyltransferase substrate binding subunit/domain |
| View | Download | 0.358 | 0.008 | calcium channel activity | a.24.17 | Group V grass pollen allergen |
| View | Download | 0.328 | N/A | N/A | a.29.2 | Bromodomain |
| View | Download | 0.326 | N/A | N/A | a.59.1 | PAH2 domain |
| View | Download | 0.315 | N/A | N/A | d.80.1 | Tautomerase/MIF |
| View | Download | 0.298 | N/A | N/A | a.1.1 | Globin-like |
| View | Download | 0.296 | N/A | N/A | a.118.9 | ENTH/VHS domain |
| View | Download | 0.292 | N/A | N/A | d.58.49 | YajQ-like |
| View | Download | 0.282 | N/A | N/A | d.228.1 | Replication modulator SeqA, C-terminal DNA-binding domain |
| View | Download | 0.275 | N/A | N/A | a.138.1 | Multiheme cytochromes |
| View | Download | 0.275 | N/A | N/A | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.251 | N/A | N/A | d.80.1 | Tautomerase/MIF |
| View | Download | 0.247 | N/A | N/A | a.77.1 | DEATH domain |
| View | Download | 0.246 | N/A | N/A | a.1.1 | Globin-like |
| View | Download | 0.242 | N/A | N/A | c.51.1 | Anticodon-binding domain of Class II aaRS |
| View | Download | 0.237 | N/A | N/A | d.110.4 | SNARE-like |
| View | Download | 0.230 | N/A | N/A | d.44.1 | Fe,Mn superoxide dismutase (SOD), C-terminal domain |
| View | Download | 0.221 | N/A | N/A | d.9.1 | Interleukin 8-like chemokines |
| View | Download | 0.221 | N/A | N/A | c.25.1 | Ferredoxin reductase-like, C-terminal NADP-linked domain |
| View | Download | 0.219 | N/A | N/A | a.7.6 | Ribosomal protein S20 |
| View | Download | 0.218 | N/A | N/A | a.77.1 | DEATH domain |
| View | Download | 0.214 | N/A | N/A | c.47.2 | RNA 3'-terminal phosphate cyclase, RPTC, insert domain |
| View | Download | 0.212 | N/A | N/A | a.7.1 | Spectrin repeat |
| View | Download | 0.206 | N/A | N/A | d.201.1 | SRP19 |
| View | Download | 0.206 | N/A | N/A | b.55.1 | PH domain-like |
| View | Download | 0.205 | N/A | N/A | a.60.2 | RuvA domain 2-like |
| View | Download | 0.205 | N/A | N/A | d.58.17 | Metal-binding domain |
|
Region A: Residues: [1438-1528] |
1 11 21 31 41 51
| | | | | |
1 GTPATVMGSA GNALFLVLFN FLSMVFILNL FVSFIVNNQA RTTGSAYFTI EEKAWLESQK 60
61 LLSQAKPKAI PNLIELSRVR QFFYQLAVEK K
|
| Detection Method: | |
| Confidence: | 3.522879 |
| Match: | 1byyA_ |
| Description: | Sodium channel IIA |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [1529-1761] |
1 11 21 31 41 51
| | | | | |
1 NFYYASFLQV VLYLHIIMLL SRSYNPGNLI GYQGVYFMFS TSVFLIQEAL HMCGEGPRLY 60
61 FRQKWNSIRL SIIIIAFIMN AVAFHVPASH YWFHNIKGFF LLVIFLFIIP QNDTLTELLE 120
121 TAMASLPPIL SLTYTWGVLF LVYAIALNQI FGLTRLGSNT TDNINFRTVI KSMIVLFRCS 180
181 FGEGWNYIMA DLTVSEPYCS SDDNSTYTDC GSETYAYLLL MSWNIISMYI FVN
|
| Detection Method: | |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
|
Region A: Residues: [1762-1891] |
1 11 21 31 41 51
| | | | | |
1 MFVSLIIGNF SYVYRSGGSR SGINRSEIKK YIEAWSKFDT DGTGELELSY LPRIMHSFDG 60
61 PLSFKIWEGR LTIKSLVENY MEVNPDDPYD VKIDLIGLNK ELNTIDKAKI IQRKLQYRRF 120
121 VQSIHYTNAY
|
| Detection Method: | |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
| MCM Score |
GO Score |
GO Term |
SCOP Match |
SCOP Description | ||
| View | Download | 0.505 | 0.237 | calcium channel activity | c.55.1 | Actin-like ATPase domain |
| View | Download | 0.504 | 0.078 | calcium channel activity | c.59.1 | MurD-like peptide ligases, peptide-binding domain |
| View | Download | 0.496 | 0.055 | calcium channel activity | d.110.4 | SNARE-like |
| View | Download | 0.303 | N/A | N/A | c.53.1 | Resolvase-like |
| View | Download | 0.300 | N/A | N/A | c.55.6 | DNA repair protein MutS, domain II |
| View | Download | 0.290 | N/A | N/A | a.24.11 | Bacterial GAP domain |
| View | Download | 0.271 | N/A | N/A | a.60.10 | Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain |
| View | Download | 0.254 | N/A | N/A | d.15.1 | Ubiquitin-like |
| View | Download | 0.254 | N/A | N/A | d.96.1 | Tetrahydrobiopterin biosynthesis enzymes-like |
| View | Download | 0.228 | N/A | N/A | c.108.1 | HAD-like |
| View | Download | 0.205 | N/A | N/A | c.25.1 | Ferredoxin reductase-like, C-terminal NADP-linked domain |
| View | Download | 0.201 | N/A | N/A | a.133.1 | Phospholipase A2, PLA2 |
|
Region A: Residues: [1892-2039] |
1 11 21 31 41 51
| | | | | |
1 NGCIRFSDLL LQIPLYTAYS ARECLGIDQY VHHLYILGKV DKYLENQRNF DVLEMVVTRW 60
61 KFHCRMKRTI EPEWDVKDPT VSSHISNINV NLEPAPGILE REPIATPRMD YGVNNFMWSP 120
121 RMNQDSTMEP PEEPIDNNDD SANDLIDR
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
SCOP Match |
SCOP Description | ||
| View | Download | 0.219 | a.26.1 | 4-helical cytokines |
| View | Download | 0.256 | a.27.1 | Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases |
| View | Download | 0.292 | f.13.1 | Family A G protein-coupled receptor-like |
| View | Download | 0.271 | a.24.9 | alpha-catenin/vinculin |
| View | Download | 0.229 | a.24.12 | Outer surface protein C (OspC) |
| View | Download | 0.207 | a.74.1 | Cyclin-like |
| View | Download | 0.201 | a.126.1 | Serum albumin-like |
| View | Download | 0.201 | a.74.1 | Cyclin-like |
