YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: RNR4
Organism: Saccharomyces cerevisiae
Length: 345 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RNR4.

Description E-value Query
Range		 Subject
Range
RRM2 - ribonucleotide reductase M2
gi|123981920, gi... - gi|123996753|gb|ABM85978.1| ribonucleotide reductase M2 polypeptide [synthetic construct], gi|123981...
 0.0 [13..345] [58..389]
RIR2_MOUSE - Ribonucleoside-diphosphate reductase subunit M2 OS=Mus musculus GN=Rrm2 PE=1 SV=1
 0.0 [13..345] [59..390]
RIR2_SPISO - Ribonucleoside-diphosphate reductase small chain OS=Spisula solidissima PE=2 SV=2
 0.0 [2..345] [39..384]
RIR2_MESAU - Ribonucleoside-diphosphate reductase subunit M2 OS=Mesocricetus auratus GN=RRM2 PE=2 SV=1
 0.0 [13..345] [59..386]
RIR2_DANRE - Ribonucleoside-diphosphate reductase subunit M2 OS=Danio rerio GN=rrm2 PE=1 SV=1
 0.0 [9..345] [48..386]
gi|929959 - gi|929959|gb|AAA74020.1| ribonuleotide reductase small subunit
 0.0 [12..345] [64..399]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
 0.0 [13..345] [32..366]
RnrS-PA - The gene Ribonucleoside diphosphate reductase small subunit is referred to in FlyBase by the symbol ...
gi|220955972, gi... - gi|220955972|gb|ACL90529.1| RnrS-PA [synthetic construct], gi|220946286|gb|ACL85686.1| CG8975-PA [sy...
 0.0 [3..345] [58..393]
gi|82469974, gi|... - gi|82469974|gb|ABB77235.1| ribonucleotide reductase small subunit R2 [Aedes aegypti], gi|157126966|r...
 0.0 [3..345] [58..397]
gi|4836362 - gi|4836362|gb|AAD30422.1|AF117061_1 ribonucleotide reductase R2 subunit [Aedes albopictus]
 0.0 [3..345] [59..398]

Back

Predicted Domain #1
Region A:
Residues: [1-27] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEAHNQFLKT FQKERHDMKE AEKDEIL

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [153-198] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NLPEVKHKAA FIERWISNDD SLYAERLVAF AAKEGIFQAG NYASMF

[Run NCBI BLAST on this sequence.]

Region C:
Residues: [221-345] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GAYTDFSCLL FAHLRTKPNP KIIEKIITEA VEIEKEYYSN SLPVEKFGMD LKSIHTYIEF  60
   61 VADGLLQGFG NEKYYNAVNP FEFMEDVATA GKTTFFEKKV SDYQKASDMS KSATPSKEIN 120
  121 FDDDF

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 10096.522879
Match: 1jk0B_
Description: Ribonucleotide reductase R2
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor 12.7205287868529 bayes_pls_golite062009
ribonucleoside-diphosphate reductase activity 12.6679910771829 bayes_pls_golite062009
oxidoreductase activity, acting on CH or CH2 groups 12.0783326936172 bayes_pls_golite062009
class I ribonucleotide reductase activity 7.27682621818194 bayes_pls_golite062009
oxidoreductase activity 2.7065388366096 bayes_pls_golite062009
binding 2.38747290927526 bayes_pls_golite062009
nucleic acid binding 1.65619019230429 bayes_pls_golite062009
DNA binding 1.60520679245579 bayes_pls_golite062009
protein binding 1.35559475972187 bayes_pls_golite062009
ion binding 0.214820110894452 bayes_pls_golite062009
cation binding 0.203880627974907 bayes_pls_golite062009
metal ion binding 0.203880627974907 bayes_pls_golite062009
catalytic activity 0.197328811494233 bayes_pls_golite062009
transition metal ion binding 0.168785605665701 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [28-57] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LMENSRRFVM FPIKYHEIWA AYKKVEASFW

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [89-126] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SISSDNLVNK YLIENFSAQL QNPEGKSFYG FQIMMENI

[Run NCBI BLAST on this sequence.]

Region C:
Residues: [215-220] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NICRDR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 10096.522879
Match: 1jk0B_
Description: Ribonucleotide reductase R2
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [58-88] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TAEEIELAKD TEDFQKLTDD QKTYIGNLLA L

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [127-152] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YSEVYSMMVD AFFKDPKNIP LFKEIA

[Run NCBI BLAST on this sequence.]

Region C:
Residues: [199-214] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 WLTDKKIMPG LAMANR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 10096.522879
Match: 1jk0B_
Description: Ribonucleotide reductase R2
Matching Structure (courtesy of the PDB):
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle