Protein Overview: RnrS-PA

General Information:
Name(s) found:	RnrS-PA / FBpp0087152 [FlyBase]
Description(s) found: Found 23 descriptions. SHOW ALL	The gene Ribonucleoside diphosphate reductase small subunit is referred to in FlyBase by the symbol Dmel\RnrS (CG8975, FBgn0011704). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:7870646..7872948. It has the cytological map location 48D5. Based on sequence similarity, it is predicted to have molecular function</span>: ribonucleoside-diphosphate reductase activity. There is experimental evidence that it is involved in the biological process</span>: activation of caspase activity. 4 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
Organism:	Drosophila melanogaster
Length:	393 amino acids
Gene Ontology:
Cellular Component:	ribonucleoside-diphosphate reductase complex [ISS][NAS]
Biological Process:	DNA replication [NAS] deoxyribonucleoside diphosphate metabolic process [IEA] oxidation reduction [IEA] activation of caspase activity [IMP]
Molecular Function:	transition metal ion binding [IEA] ribonucleoside-diphosphate reductase activity [ISS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASKENIADN MEKFSLKSPS KKILTDSTNN VRKMSIGHEA NGQLAKESST VNGIGKSANS  60
   61 LMEKSVTPFD PSLEPLLREN PRRFVIFPIQ YHDIWQMYKK AEASFWTVEE VDLSKDLTDW 120
  121 HRLKDDERHF ISHVLAFFAA SDGIVNENLV ERFSQEVQIT EARCFYGFQI AMENVHSEMY 180
  181 SVLIDTYIRD PHQREYLFNA IETMPAVKRK ADWALSWISS KSANFGERII AFAAVEGIFF 240
  241 SGSFASIFWL KKRGLMPGLT FSNELISRDE GLHCDFAVLM FQHLVQRPKR ERIIEIIRDA 300
  301 VAIEQEFLTD ALPVNLIGMN CDLMSQYIEF VADRLLVELG VGKIYNTKNP FNFMEMISLD 360
  361 GKTNFFEKKV GEYQRMGVVS NPLDNVFTLD ADF

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Searching the YRC Public Image Repository, found results:

Currently showing to of results.

[View Search in the YRC Public Image Repository]

Searching the YRC Public Image Repository, found no results.

Ginzu Version Information

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

Gene Ontology predictions

Term	Confidence	Notes
oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor	12.7205287868529	bayes_pls_golite062009
ribonucleoside-diphosphate reductase activity	12.6679910771829	bayes_pls_golite062009
oxidoreductase activity, acting on CH or CH2 groups	12.0783326936172	bayes_pls_golite062009
class I ribonucleotide reductase activity	7.27682621818194	bayes_pls_golite062009
binding	2.38747290927526	bayes_pls_golite062009
nucleic acid binding	1.75581372355926	bayes_pls_golite062009
DNA binding	1.75528223979795	bayes_pls_golite062009
protein binding	1.35559475972187	bayes_pls_golite062009
transition metal ion binding	0.919082601902017	bayes_pls_golite062009
cation binding	0.635432538918818	bayes_pls_golite062009
metal ion binding	0.635432538918818	bayes_pls_golite062009
ion binding	0.628186057553096	bayes_pls_golite062009
catalytic activity	0.197328811494233	bayes_pls_golite062009

Source: Reynolds et al. 2008. Manuscript submitted

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..393]	PSI-BLAST	127.0	Ribonucleotide reductase R2

Protein Overview: RnrS-PA

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: