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Protein Overview: RIR2_MOUSE

General Information:
Name(s) found: RIR2_MOUSE [Swiss-Prot]
Description(s) found:
Found 49 descriptions.
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  • Ribonucleoside-diphosphate reductase subunit M2 OS=Mus musculus GN=Rrm2 PE=1 SV=1 [Swiss-Prot]
    • Organism: Mus musculus
    Length: 390 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLSVRTPLAT IADQQQLQLS PLKRLTLADK ENTPPTLSST RVLASKAARR IFQDSAELES  60
   61 KAPTNPSVED EPLLRENPRR FVVFPIEYHD IWQMYKKAEA SFWTAEEVDL SKDIQHWEAL 120
  121 KPDERHFISH VLAFFAASDG IVNENLVERF SQEVQVTEAR CFYGFQIAME NIHSEMYSLL 180
  181 IDTYIKDPKE REYLFNAIET MPCVKKKADW ALRWIGDKEA TYGERVVAFA AVEGIFFSGS 240
  241 FASIFWLKKR GLMPGLTFSN ELISRDEGLH CDFACLMFKH LVHKPAEQRV REIITNAVRI 300
  301 EQEFLTEALP VKLIGMNCTL MKQYIEFVAD RLMLELGFNK IFRVENPFDF MENISLEGKT 360
  361 NFFEKRVGEY QRMGVMSNST ENSFTLDADF

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..390] PSI-BLAST 140.0 Ribonucleotide reductase R2

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor
    		•  12.7205287868529 bayes_pls_golite062009
  • ribonucleoside-diphosphate reductase activity
    		•  12.6679910771829 bayes_pls_golite062009
  • oxidoreductase activity, acting on CH or CH2 groups
    		•  12.0783326936172 bayes_pls_golite062009
  • class I ribonucleotide reductase activity
    		•  7.27682621818194 bayes_pls_golite062009
  • oxidoreductase activity
    		•  2.7065388366096 bayes_pls_golite062009
  • binding
    		•  2.38747290927526 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.65619019230429 bayes_pls_golite062009
  • DNA binding
    		•  1.60520679245579 bayes_pls_golite062009
  • protein binding
    		•  1.35559475972187 bayes_pls_golite062009
  • transition metal ion binding
    		•  0.919082601902017 bayes_pls_golite062009
  • cation binding
    		•  0.635432538918818 bayes_pls_golite062009
  • metal ion binding
    		•  0.635432538918818 bayes_pls_golite062009
  • ion binding
    		•  0.628186057553096 bayes_pls_golite062009
  • catalytic activity
    		•  0.197328811494233 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.64

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle