| Protein: | VAS1 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 1104 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for VAS1.
| Description | E-value | Query Range |
Subject Range |
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0.0 | [1..1104] | [1..1104] |
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0.0 | [54..1102] | [211..1262] |
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0.0 | [54..1102] | [211..1263] |
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0.0 | [33..1101] | [27..1100] |
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0.0 | [46..1102] | [145..1216] |
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Region A: Residues: [1-121] |
1 11 21 31 41 51
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1 MNKWLNTLSK TFTFRLLNCH YRRSLPLCQN FSLKKSLTHN QVRFFKMSDL DNLPPVDPKT 60
61 GEVIINPLKE DGSPKTPKEI EKEKKKAEKL LKFAAKQAKK NAAATTGASQ KKPKKKKEVE 120
121 P
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| Detection Method: |  |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
| MCM Score |
GO Score |
GO Term |
SCOP Match |
SCOP Description | ||
| View | Download | 0.543 | 0.091 | valine-tRNA ligase activity | a.24.3 | Cytochromes |
| View | Download | 0.520 | 0.049 | valine-tRNA ligase activity | a.24.9 | alpha-catenin/vinculin |
| View | Download | 0.604 | 0.011 | valine-tRNA ligase activity | f.36.1 | Neurotransmitter-gated ion-channel pransmembrane pore |
| View | Download | 0.551 | N/A | N/A | i.11.1 | Computational models partly based on NMR data |
| View | Download | 0.511 | N/A | N/A | i.11.1 | Computational models partly based on NMR data |
| View | Download | 0.449 | N/A | N/A | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.431 | N/A | N/A | a.24.9 | alpha-catenin/vinculin |
| View | Download | 0.428 | N/A | N/A | a.24.3 | Cytochromes |
| View | Download | 0.427 | N/A | N/A | a.24.10 | Histidine-containing phosphotransfer domain, HPT domain |
| View | Download | 0.425 | N/A | N/A | a.1.1 | Globin-like |
| View | Download | 0.413 | N/A | N/A | a.48.1 | N-terminal domain of cbl (N-cbl) |
| View | Download | 0.390 | N/A | N/A | a.24.10 | Histidine-containing phosphotransfer domain, HPT domain |
| View | Download | 0.390 | N/A | N/A | a.90.1 | Transcription factor STAT-4 N-domain |
| View | Download | 0.385 | N/A | N/A | a.133.1 | Phospholipase A2, PLA2 |
| View | Download | 0.379 | N/A | N/A | a.72.1 | Functional domain of the splicing factor Prp18 |
| View | Download | 0.365 | N/A | N/A | a.7.1 | Spectrin repeat |
| View | Download | 0.363 | N/A | N/A | a.24.3 | Cytochromes |
| View | Download | 0.356 | N/A | N/A | a.25.2 | Thermoplasma ferritin-like 4-helical bundle |
| View | Download | 0.352 | N/A | N/A | a.47.2 | t-snare proteins |
| View | Download | 0.346 | N/A | N/A | a.24.3 | Cytochromes |
| View | Download | 0.343 | N/A | N/A | a.118.1 | ARM repeat |
| View | Download | 0.335 | N/A | N/A | f.36.1 | Neurotransmitter-gated ion-channel pransmembrane pore |
| View | Download | 0.328 | N/A | N/A | g.36.1 | Ferredoxin thioredoxin reductase (FTR), catalytic beta chain |
| View | Download | 0.326 | N/A | N/A | a.25.2 | Thermoplasma ferritin-like 4-helical bundle |
| View | Download | 0.324 | N/A | N/A | a.121.1 | Tetracyclin repressor-like, C-terminal domain |
| View | Download | 0.317 | N/A | N/A | d.92.2 | beta-N-acetylhexosaminidase-like domain |
| View | Download | 0.312 | N/A | N/A | d.58.9 | RuBisCO, large subunit, small (N-terminal) domain |
| View | Download | 0.310 | N/A | N/A | i.11.1 | Computational models partly based on NMR data |
| View | Download | 0.304 | N/A | N/A | a.7.8 | GAT domain |
| View | Download | 0.302 | N/A | N/A | a.25.1 | Ferritin-like |
| View | Download | 0.291 | N/A | N/A | a.1.1 | Globin-like |
| View | Download | 0.285 | N/A | N/A | a.1.1 | Globin-like |
| View | Download | 0.275 | N/A | N/A | c.2.1 | NAD(P)-binding Rossmann-fold domains |
| View | Download | 0.263 | N/A | N/A | a.116.1 | GTPase activation domain, GAP |
| View | Download | 0.236 | N/A | N/A | f.1.4 | Bcl-2 inhibitors of programmed cell death |
| View | Download | 0.232 | N/A | N/A | a.81.1 | N-terminal domain of DnaB helicase |
| View | Download | 0.228 | N/A | N/A | a.7.1 | Spectrin repeat |
| View | Download | 0.226 | N/A | N/A | f.1.4 | Bcl-2 inhibitors of programmed cell death |
| View | Download | 0.221 | N/A | N/A | a.24.7 | FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) |
| View | Download | 0.209 | N/A | N/A | a.78.1 | Fatty acid responsive transcription factor FadR, C-terminal domain |
| View | Download | 0.208 | N/A | N/A | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.204 | N/A | N/A | a.118.9 | ENTH/VHS domain |
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Region A: Residues: [122-169] |
1 11 21 31 41 51
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1 IPEFIDKTVP GEKKILVSLD DPALKAYNPA NVESSWYDWW IKTGVFEP
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Region B: Residues: [196-218] |
1 11 21 31 41 51
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1 LHIGHALTIA IQDSLIRYNR MKG
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Region C: Residues: [693-945] |
1 11 21 31 41 51
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1 HSLVRDAQGR KMSKSLGNVI DPLDVITGIK LDDLHAKLLQ GNLDPREVEK AKIGQKESYP 60
61 NGIPQCGTDA MRFALCAYTT GGRDINLDIL RVEGYRKFCN KIYQATKFAL MRLGDDYQPP 120
121 ATEGLSGNES LVEKWILHKL TETSKIVNEA LDKRDFLTST SSIYEFWYLI CDVYIENSKY 180
181 LIQEGSAIEK KSAKDTLYIL LDNALKLIHP FMPFISEEMW QRLPKRSTEK AASIVKASYP 240
241 VYVSEYDDVK SAN
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| Detection Method: | |
| Confidence: | 2610.0 |
| Match: | 1gaxA_ |
| Description: | Valyl-tRNA synthetase (ValRS) C-terminal domain; Valyl-tRNA synthetase (ValRS) |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| ligase activity, forming aminoacyl-tRNA and related compounds | 8.24066297904343 | bayes_pls_golite062009 |
| ligase activity, forming carbon-oxygen bonds | 8.24066297904343 | bayes_pls_golite062009 |
| aminoacyl-tRNA ligase activity | 8.23006189348918 | bayes_pls_golite062009 |
| valine-tRNA ligase activity | 7.13767629265822 | bayes_pls_golite062009 |
| leucine-tRNA ligase activity | 7.03538514482698 | bayes_pls_golite062009 |
| ligase activity | 6.98979325804867 | bayes_pls_golite062009 |
| isoleucine-tRNA ligase activity | 6.38633897147986 | bayes_pls_golite062009 |
| methionine-tRNA ligase activity | 2.56893064485672 | bayes_pls_golite062009 |
| catalytic activity | 2.26766689929461 | bayes_pls_golite062009 |
| tyrosine-tRNA ligase activity | 1.88984817882585 | bayes_pls_golite062009 |
| arginine-tRNA ligase activity | 1.51931993626103 | bayes_pls_golite062009 |
| tryptophan-tRNA ligase activity | 1.14187887833901 | bayes_pls_golite062009 |
| binding | 0.987705174689351 | bayes_pls_golite062009 |
| cysteine-tRNA ligase activity | 0.844943947059557 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 0.625793556381714 | bayes_pls_golite062009 |
| nucleic acid binding | 0.514662028202085 | bayes_pls_golite062009 |
| nucleotidyltransferase activity | 0.2293846471193 | bayes_pls_golite062009 |
| protein binding | 0.143518788844143 | bayes_pls_golite062009 |
| glutamine-tRNA ligase activity | 0.118292082006187 | bayes_pls_golite062009 |
| RNA binding | 0.0208852714448815 | bayes_pls_golite062009 |
| mRNA binding | 2.82524485163416E-5 | bayes_pls_golite062009 |
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Region A: Residues: [170-195] |
1 11 21 31 41 51
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1 EFTADGKVKP EGVFCIPAPP PNVTGA
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Region B: Residues: [219-357] |
1 11 21 31 41 51
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1 KTVLFLPGFD HAGIATQSVV EKQIWAKDRK TRHDYGREAF VGKVWEWKEE YHSRIKNQIQ 60
61 KLGASYDWSR EAFTLSPELT KSVEEAFVRL HDEGVIYRAS RLVNWSVKLN TAISNLEVEN 120
121 KDVKSRTLLS VPGYDEKVE
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Region C: Residues: [505-692] |
1 11 21 31 41 51
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1 TIPTCSRSGD IIEPLLKPQW WVSQSEMAKD AIKVVRDGQI TITPKSSEAE YFHWLGNIQD 60
61 WCISRQLWWG HRCPVYFINI EGEEHDRIDG DYWVAGRSME EAEKKAAAKY PNSKFTLEQD 120
121 EDVLDTWFSS GLWPFSTLGW PEKTKDMETF YPFSMLETGW DILFFWVTRM ILLGLKLTGS 180
181 VPFKEVFC
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Region D: Residues: [946-1104] |
1 11 21 31 41 51
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1 AYDLVLNITK EARSLLSEYN ILKNGKVFVE SNHEEYFKTA EDQKDSIVSL IKAIDEVTVV 60
61 RDASEIPEGC VLQSVNPEVN VHLLVKGHVD IDAEIAKVQK KLEKAKKSKN GIEQTINSKD 120
121 YETKANTQAK EANKSKLDNT VAEIEGLEAT IENLKRLKL
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| Detection Method: | |
| Confidence: | 2610.0 |
| Match: | 1gaxA_ |
| Description: | Valyl-tRNA synthetase (ValRS) C-terminal domain; Valyl-tRNA synthetase (ValRS) |
| Matching Structure (courtesy of the PDB): |
|
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Region A: Residues: [358-504] |
1 11 21 31 41 51
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1 FGVLTSFAYP VIGSDEKLII ATTRPETIFG DTAVAVHPDD DRYKHLHGKF IQHPFLPRKI 60
61 PIITDKEAVD MEFGTGAVKI TPAHDQNDYN TGKRHNLEFI NILTDDGLLN EECGPEWQGM 120
121 KRFDARKKVI EQLKEKNLYV GQEDNEM
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| Detection Method: | |
| Confidence: | 2610.0 |
| Match: | 1gaxA_ |
| Description: | Valyl-tRNA synthetase (ValRS) C-terminal domain; Valyl-tRNA synthetase (ValRS) |
| Matching Structure (courtesy of the PDB): |
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