YRC Public Data Repository - Protein Structure Prediction

Protein:	MMS2
Organism:	Saccharomyces cerevisiae
Length:	137 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MMS2.

Description	E-value	Query Range	Subject Range
gi\|109066782 - gi\|109066782\|ref\|XP_001096263.1\| PREDICTED: similar to ubiquitin-conjugating enzyme E2D 4 (putative)... gi\|114613001, gi... - gi\|114613001\|ref\|XP_519070.2\| PREDICTED: ubiquitin-conjugating enzyme E2D 4 (putative) isoform 4 [Pa... UBE2D4 - ubiquitin-conjugating enzyme E2D 4 (putative)	8.0E-48	[6..137]	[2..127]
gi\|18417097, gi\|... - gi\|66354424\|gb\|AAY44849.1\| ubiquitinating enzyme [Arabidopsis thaliana], gi\|18417097\|ref\|NP_567791.1...	1.0E-47	[6..137]	[32..157]
gi\|456568 - gi\|456568\|gb\|AAA64427.1\| ubiquitin conjugating enzyme	2.0E-47	[6..137]	[2..127]
gi\|187034543, gi... - gi\|39593702\|emb\|CAE61994.1\| Hypothetical protein CBG06002 [Caenorhabditis briggsae], gi\|187034543\|em... gi\|170589261, gi... - gi\|170589261\|ref\|XP_001899392.1\| ubiquitin-conjugating enzyme ubc-2 [Brugia malayi], gi\|158593605\|gb... gi\|209489351 - gi\|209489351\|gb\|ACI49123.1\| hypothetical protein Cbre_JD14.011 [Caenorhabditis brenneri] let-70 - ubiquitin-conjugating enzyme E2-17 KD status:Confirmed UniProt:P35129 protein_id:CAA92745.1 CRE12761, FL81_0... - RP40331 WBGene00062522 locus:Cre-let-70 status:Confirmed, null gi\|157755991 - gi\|157755991\|ref\|XP_001670339.1\| Hypothetical protein CBG06002 [Caenorhabditis briggsae AF16]	2.0E-47	[6..137]	[2..127]
UBC4_SOLLC - Ubiquitin-conjugating enzyme E2-17 kDa OS=Solanum lycopersicum PE=2 SV=1 gi\|83283973 - gi\|83283973\|gb\|ABC01894.1\| ubiquitin-conjugating enzyme E2-like protein [Solanum tuberosum]	3.0E-47	[6..137]	[2..127]

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Predicted Domain #1

Region A:
Residues: [1-137]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSKVPRNFRL LEELEKGEKG FGPESCSYGL ADSDDITMTK WNGTILGPPH SNHENRIYSL  60
   61 SIDCGPNYPD SPPKVTFISK INLPCVNPTT GEVQTDFHTL RDWKRAYTME TLLLDLRKEM 120
  121 ATPANKKLRQ PKEGETF

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	785.529817
Match:	1jatB_
Description:	Ubiquitin conjugating enzyme, UBC
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
ubiquitin-protein ligase activity	7.07009148420636	bayes_pls_golite062009
small conjugating protein ligase activity	7.03976510657099	bayes_pls_golite062009
acid-amino acid ligase activity	6.00007452476109	bayes_pls_golite062009
ligase activity, forming carbon-nitrogen bonds	5.06177413452771	bayes_pls_golite062009
transcription regulator activity	1.9559492182519	bayes_pls_golite062009
ligase activity	1.88059319399119	bayes_pls_golite062009
nucleic acid binding	1.83472092683523	bayes_pls_golite062009
DNA binding	1.77393825735008	bayes_pls_golite062009
binding	1.75350658654805	bayes_pls_golite062009
catalytic activity	0.891402822028799	bayes_pls_golite062009
SUMO ligase activity	0.843488104298821	bayes_pls_golite062009
protein binding	0.726328463755484	bayes_pls_golite062009
NEDD8 ligase activity	0.715654744941217	bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor	0.58835335751383	bayes_pls_golite062009
kinase activity	0.519703305315987	bayes_pls_golite062009
protein kinase activity	0.443948654247666	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	0.373779304908933	bayes_pls_golite062009
protein serine/threonine kinase activity	0.182854082413338	bayes_pls_golite062009
transferase activity	0.0984525836903841	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: