| Protein: | CDC14 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 551 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CDC14.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..551] | [1..551] |
|
|
0.0 | [11..547] | [11..539] |
|
|
0.0 | [12..538] | [13..526] |
|
|
0.0 | [7..548] | [8..495] |
|
Region A: Residues: [1-85] |
1 11 21 31 41 51
| | | | | |
1 MRRSVYLDNT IEFLRGRVYL GAYDYTPEDT DELVFFTVED AIFYNSFHLD FGPMNIGHLY 60
61 RFAVIFHEIL NDPENANKAV VFYSS
|
| Detection Method: |  |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
| MCM Score |
GO Score |
GO Term |
SCOP Match |
SCOP Description | ||
| View | Download | 0.548 | 0.056 | spindle pole body | d.58.17 | Metal-binding domain |
| View | Download | 0.522 | 0.046 | spindle pole body | a.60.1 | SAM/Pointed domain |
| View | Download | 0.492 | 0.027 | spindle pole body | a.2.3 | Chaperone J-domain |
| View | Download | 0.508 | 0.010 | spindle pole body | a.60.9 | lambda integrase-like, N-terminal domain |
| View | Download | 0.470 | 0.003 | spindle pole body | a.4.9 | Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 |
| View | Download | 0.444 | N/A | N/A | a.64.1 | Saposin |
| View | Download | 0.426 | N/A | N/A | c.55.7 | Methylated DNA-protein cysteine methyltransferase domain |
| View | Download | 0.404 | N/A | N/A | d.50.2 | Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain |
| View | Download | 0.400 | N/A | N/A | a.46.1 | Methionine synthase domain |
| View | Download | 0.392 | N/A | N/A | d.16.1 | FAD-linked reductases, C-terminal domain |
| View | Download | 0.389 | N/A | N/A | a.39.1 | EF-hand |
| View | Download | 0.385 | N/A | N/A | d.192.1 | YlxR-like |
| View | Download | 0.381 | N/A | N/A | a.46.1 | Methionine synthase domain |
| View | Download | 0.379 | N/A | N/A | c.58.1 | Aminoacid dehydrogenase-like, N-terminal domain |
| View | Download | 0.374 | N/A | N/A | a.8.2 | Plasmid maintenance system epsilon/zeta, antidote epsilon subunit |
| View | Download | 0.373 | N/A | N/A | a.60.9 | lambda integrase-like, N-terminal domain |
| View | Download | 0.371 | N/A | N/A | d.141.1 | Ribosomal protein L6 |
| View | Download | 0.369 | N/A | N/A | a.21.1 | HMG-box |
| View | Download | 0.367 | N/A | N/A | a.80.1 | DNA polymerase III clamp loader subunits, C-terminal domain |
| View | Download | 0.367 | N/A | N/A | a.80.1 | DNA polymerase III clamp loader subunits, C-terminal domain |
| View | Download | 0.355 | N/A | N/A | a.80.1 | DNA polymerase III clamp loader subunits, C-terminal domain |
| View | Download | 0.347 | N/A | N/A | d.192.1 | YlxR-like |
| View | Download | 0.342 | N/A | N/A | b.43.3 | Translation proteins |
| View | Download | 0.334 | N/A | N/A | d.50.3 | PI-Pfui intein middle domain |
| View | Download | 0.324 | N/A | N/A | a.37.1 | A DNA-binding domain in eukaryotic transcription factors |
| View | Download | 0.324 | N/A | N/A | a.50.1 | Anaphylotoxins (complement system) |
| View | Download | 0.320 | N/A | N/A | a.4.1 | Homeodomain-like |
| View | Download | 0.317 | N/A | N/A | a.80.1 | DNA polymerase III clamp loader subunits, C-terminal domain |
| View | Download | 0.317 | N/A | N/A | a.60.8 | HRDC-like |
| View | Download | 0.314 | N/A | N/A | a.109.1 | Class II MHC-associated invariant chain ectoplasmic trimerization domain |
| View | Download | 0.306 | N/A | N/A | a.80.1 | DNA polymerase III clamp loader subunits, C-terminal domain |
| View | Download | 0.301 | N/A | N/A | a.37.1 | A DNA-binding domain in eukaryotic transcription factors |
| View | Download | 0.299 | N/A | N/A | a.64.1 | Saposin |
| View | Download | 0.297 | N/A | N/A | d.49.1 | Signal recognition particle alu RNA binding heterodimer, SRP9/14 |
| View | Download | 0.295 | N/A | N/A | a.64.1 | Saposin |
| View | Download | 0.290 | N/A | N/A | a.13.1 | alpha-2-Macroglobulin receptor associated protein (RAP) domain 1 |
| View | Download | 0.276 | N/A | N/A | b.6.1 | Cupredoxins |
| View | Download | 0.272 | N/A | N/A | a.64.1 | Saposin |
| View | Download | 0.270 | N/A | N/A | a.60.1 | SAM/Pointed domain |
| View | Download | 0.269 | N/A | N/A | a.37.1 | A DNA-binding domain in eukaryotic transcription factors |
| View | Download | 0.266 | N/A | N/A | a.60.2 | RuvA domain 2-like |
| View | Download | 0.265 | N/A | N/A | a.35.1 | lambda repressor-like DNA-binding domains |
| View | Download | 0.263 | N/A | N/A | a.50.1 | Anaphylotoxins (complement system) |
| View | Download | 0.263 | N/A | N/A | d.192.1 | YlxR-like |
| View | Download | 0.259 | N/A | N/A | a.60.1 | SAM/Pointed domain |
| View | Download | 0.259 | N/A | N/A | b.40.2 | Bacterial enterotoxins |
| View | Download | 0.252 | N/A | N/A | a.7.6 | Ribosomal protein S20 |
| View | Download | 0.249 | N/A | N/A | a.23.1 | HSC20 (HSCB), C-terminal oligomerisation domain |
| View | Download | 0.236 | N/A | N/A | a.76.1 | Iron-dependent represor protein, dimerization domain |
| View | Download | 0.233 | N/A | N/A | d.109.1 | Actin depolymerizing proteins |
| View | Download | 0.232 | N/A | N/A | a.39.1 | EF-hand |
| View | Download | 0.232 | N/A | N/A | d.110.4 | SNARE-like |
| View | Download | 0.231 | N/A | N/A | b.6.1 | Cupredoxins |
| View | Download | 0.229 | N/A | N/A | a.118.1 | ARM repeat |
| View | Download | 0.223 | N/A | N/A | a.24.17 | Group V grass pollen allergen |
| View | Download | 0.217 | N/A | N/A | d.93.1 | SH2 domain |
| View | Download | 0.215 | N/A | N/A | b.40.2 | Bacterial enterotoxins |
| View | Download | 0.211 | N/A | N/A | b.40.2 | Bacterial enterotoxins |
| View | Download | 0.209 | N/A | N/A | d.58.42 | N-utilization substance G protein NusG, N-terminal domain |
| View | Download | 0.202 | N/A | N/A | a.108.1 | Ribosomal protein L7/12, oligomerisation (N-terminal) domain |
| Term | Confidence | Notes |
| phosphoprotein phosphatase activity | 7.30669036331612 | bayes_pls_golite062009 |
| phosphatase activity | 6.6585143972081 | bayes_pls_golite062009 |
| phosphoric ester hydrolase activity | 6.44546424348532 | bayes_pls_golite062009 |
| hydrolase activity, acting on ester bonds | 5.70473199778334 | bayes_pls_golite062009 |
| protein tyrosine phosphatase activity | 5.3097342170423 | bayes_pls_golite062009 |
| alpha-actinin binding | 3.03868073080583 | bayes_pls_golite062009 |
| actin binding | 2.96334024905854 | bayes_pls_golite062009 |
| transmembrane receptor protein phosphatase activity | 2.94635032478625 | bayes_pls_golite062009 |
| transmembrane receptor protein tyrosine phosphatase activity | 2.94635032478625 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 2.93073637718155 | bayes_pls_golite062009 |
| protein tyrosine/serine/threonine phosphatase activity | 2.77531895423367 | bayes_pls_golite062009 |
| protein serine/threonine phosphatase activity | 2.49496709551693 | bayes_pls_golite062009 |
| protein binding | 2.12487185456363 | bayes_pls_golite062009 |
| binding | 2.06015698112379 | bayes_pls_golite062009 |
| hydrolase activity | 1.9069800114411 | bayes_pls_golite062009 |
| nucleic acid binding | 1.24416639415232 | bayes_pls_golite062009 |
| DNA binding | 1.19665037078743 | bayes_pls_golite062009 |
| inositol or phosphatidylinositol phosphatase activity | 1.1200449509328 | bayes_pls_golite062009 |
| catalytic activity | 1.06283028154109 | bayes_pls_golite062009 |
| lipid phosphatase activity | 1.05085928819585 | bayes_pls_golite062009 |
| phosphoprotein phosphatase inhibitor activity | 0.979874859714334 | bayes_pls_golite062009 |
| non-membrane spanning protein tyrosine phosphatase activity | 0.724257798127697 | bayes_pls_golite062009 |
| transporter activity | 0.653544405131346 | bayes_pls_golite062009 |
| phosphatase inhibitor activity | 0.64132831041331 | bayes_pls_golite062009 |
| protein kinase activity | 0.569334963316149 | bayes_pls_golite062009 |
| transmembrane transporter activity | 0.401311298433519 | bayes_pls_golite062009 |
| phosphotransferase activity, alcohol group as acceptor | 0.386515379888428 | bayes_pls_golite062009 |
| kinase activity | 0.380629891538418 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 0.343848090522899 | bayes_pls_golite062009 |
| transmembrane receptor activity | 0.291525352733402 | bayes_pls_golite062009 |
| receptor activity | 0.191946218805025 | bayes_pls_golite062009 |
| enzyme binding | 0.150910330021054 | bayes_pls_golite062009 |
| kinase binding | 0.141802531311128 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 0.09373220143933 | bayes_pls_golite062009 |
| protein kinase binding | 0.062562314598915 | bayes_pls_golite062009 |
|
Region A: Residues: [86-477] |
1 11 21 31 41 51
| | | | | |
1 ASTRQRANAA CMLCCYMILV QAWTPHQVLQ PLAQVDPPFM PFRDAGYSNA DFEITIQDVV 60
61 YGVWRAKEKG LIDLHSFNLE SYEKYEHVEF GDFNVLTPDF IAFASPQEDH PKGYLATKSS 120
121 HLNQPFKSVL NFFANNNVQL VVRLNSHLYN KKHFEDIGIQ HLDLIFEDGT CPDLSIVKNF 180
181 VGAAETIIKR GGKIAVHCKA GLGRTGCLIG AHLIYTYGFT ANECIGFLRF IRPGMVVGPQ 240
241 QHWLYLHQND FREWKYTTRI SLKPSEAIGG LYPLISLEEY RLQKKKLKDD KRVAQNNIEG 300
301 ELRDLTMTPP SNGHGALSAR NSSQPSTANN GSNSFKSSAV PQTSPGQPRK GQNGSNTIED 360
361 INNNRNPTSH ANRKVVIESN NSDDESMQDT NG
|
| Detection Method: | |
| Confidence: | 85.69897 |
| Match: | 1larA_ |
| Description: | RPTP Lar |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [478-551] |
1 11 21 31 41 51
| | | | | |
1 TSNHYPKVSR KKNDISSASS SRMEDNEPSA TNINNAADDT ILRQLLPKNR RVTSGRRTTS 60
61 AAGGIRKISG SIKK
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
SCOP Match |
SCOP Description | ||
| View | Download | 0.519 | a.156.1 | S13-like H2TH domain |
| View | Download | 0.409 | a.56.1 | CO dehydrogenase ISP C-domain like |
| View | Download | 0.324 | a.28.3 | Retrovirus capsid protein C-terminal domain |
| View | Download | 0.519 | a.156.1 | S13-like H2TH domain |
| View | Download | 0.409 | a.56.1 | CO dehydrogenase ISP C-domain like |
| View | Download | 0.324 | a.28.3 | Retrovirus capsid protein C-terminal domain |
| View | Download | 0.319 | a.60.11 | Hypothetical protein YjbJ |
| View | Download | 0.319 | a.60.11 | Hypothetical protein YjbJ |
| View | Download | 0.310 | a.56.1 | CO dehydrogenase ISP C-domain like |
| View | Download | 0.310 | a.56.1 | CO dehydrogenase ISP C-domain like |
| View | Download | 0.299 | a.159.1 | Protein serine/threonine phosphatase 2C, C-terminal domain |
| View | Download | 0.285 | a.44.1 | Disulphide-bond formation facilitator (DSBA), insertion domain |
| View | Download | 0.284 | a.56.1 | CO dehydrogenase ISP C-domain like |
| View | Download | 0.252 | a.60.5 | Barrier-to-autointegration factor, BAF |
| View | Download | 0.226 | a.3.1 | Cytochrome c |
| View | Download | 0.216 | a.24.13 | Domain of the SRP/SRP receptor G-proteins |
