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View Structure Prediction Details

Protein: POL5
Organism: Saccharomyces cerevisiae
Length: 1022 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for POL5.

Description E-value Query
Range
Subject
Range
POL5 - DNA Polymerase phi; has sequence similarity to the human MybBP1A and weak sequence similarity to B-t...
DPO5_YEAST - DNA polymerase V OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=POL5 PE=1 SV=1
0.0 [1..1022] [1..1022]
pol5 - DNA polymerase phi
DPO5_SCHPO - DNA polymerase V OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=pol5 PE=1 SV=2
0.0 [1..1010] [1..928]
gi|7657351, gi|6... - gi|7657351|ref|NP_055335.1| MYB binding protein 1a [Homo sapiens], gi|6959304|gb|AAF33021.1|AF147709...
0.0 [7..859] [36..836]
gi|19070182 - gi|19070182|gb|AAL83748.1|AF345640_1 myb-binding protein 1a [Mus musculus]
0.0 [7..859] [34..835]
gi|7514041, gi|1... - pir||T32731 PAR interacting protein - rat, gi|2253211|gb|AAB62878.1| PAR interacting protein [Rattu...
0.0 [44..859] [1..766]
gi|15237690, gi|... - gi|15237690|ref|NP_201247.1| DNA polymerase V family [Arabidopsis thaliana], gi|10178223|dbj|BAB1160...
0.0 [7..690] [124..893]
gi|6474809 - gi|6474809|dbj|BAA87301.1| DNA polymerase V [Schizosaccharomyces pombe]
3.0E-37 [641..853] [1..183]

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Predicted Domain #1
Region A:
Residues: [1-694]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTGKVNRDLF FKLASDLREE RLHAAVALIK DLSALDLPDD AEEWSYVLNR LIKGLSSDRN  60
   61 SARLGFSLCL TEVINLAVNM PPGQRPKGLE STNEFLSTLS TILNVNVNEG TKKSMKGKDE 120
  121 RGILFGKLFG LKSLLNEPLF SEIFVKDLEK GNTEFFIRFT EQLIDLALKK NWIKEPCFFT 180
  181 LFQTMKMLLP FMDESSAEKI LLIYDKYDLT LTNEGLSTYL LLKYEGDESL IPSVLDLKNP 240
  241 GWKDNDPLAR GNLPLLTKVL RNSSVIPDAN GGLKETKKQK NTNWNPRLHF VWSVLLPLFG 300
  301 NGKLENTSHI SKKRKKTNNK KVQNSIQFPE FWKMAVDESF FNEKASSERK YLGFLIIDAA 360
  361 FKAVPGSYIG FCFSQNVMRT LINQSIDSQR VLNKISQLTL DSIVKACEED SANRLVPCLN 420
  421 AMLFGPHGSI NFDKLTKSGT VSKLIAIKEL PSTVLAQLLD VFFLQLQDKK GVLSHTLFAL 480
  481 DSILHIVRAH KVEINDMDIM KPVLRPIVYM AFFKHTSDDL KLEQLHELAK ERLYSILGEL 540
  541 TINKEIRCKD PEINSWQYLT LKLILDIENS HVGDLINPLD ENLENIKNEA ISCLSKVCRS 600
  601 RTAQSWGLST LLSMCLVQLY AGDTDSISVI EELCEFSKHE NNSMVGITEI LLSLLAQKKA 660
  661 LLRKLSLIIW QQFIEEVGLE ELQILLDILK AREN

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term Confidence Notes
binding 3.4840129457355 bayes_pls_golite062009
nucleic acid binding 2.27889073911459 bayes_pls_golite062009
transcription regulator activity 2.19067997822967 bayes_pls_golite062009
actin binding 1.7228099998642 bayes_pls_golite062009
DNA binding 1.71679738414596 bayes_pls_golite062009
protein binding 1.41127231900194 bayes_pls_golite062009
transcription factor activity 1.01026749293758 bayes_pls_golite062009
transition metal ion binding 0.301301625996911 bayes_pls_golite062009
structural molecule activity 0.279533827088985 bayes_pls_golite062009
RNA binding 0.243875756041061 bayes_pls_golite062009
transcription activator activity 0.142253868848261 bayes_pls_golite062009
transcription factor binding 8.79739237675814E-4 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [695-868]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KQGFAQLFEG EEEFEEIKEE NDASEDESKT GSESESESES DSDDADEKDE EDEANEDILN  60
   61 IDKEATSALV KALNLPDNIV NDKGEVDLDQ LEGLSDDGGD DEDEESMDDE KMMELDDQLS 120
  121 EIFKRRKEAL SSISTGNQRK FEVKQSRENV ISFKHRVVDM LAVYVKYCEK LTLA

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [869-1022]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NKSEHSNNLG GSLSKLVYFI IPMLKCVNET LDRPLADKIS KLLKGKIFKI KVTAFKDMNK  60
   61 DIELMDLLKK THKLMLTSKP GQHAAVFYSM CSTSSLFLSK LYVEIGGNDK LDELIDLYTA 120
  121 TTKEWMQKGK CGPNIFIDFI NWLSSKKQTV MDKE

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [866-1022]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TLANKSEHSN NLGGSLSKLV YFIIPMLKCV NETLDRPLAD KISKLLKGKI FKIKVTAFKD  60
   61 MNKDIELMDL LKKTHKLMLT SKPGQHAAVF YSMCSTSSLF LSKLYVEIGG NDKLDELIDL 120
  121 YTATTKEWMQ KGKCGPNIFI DFINWLSSKK QTVMDKE

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle