| Protein: | MUS81 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 632 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MUS81.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..632] | [1..632] |
|
|
0.0 | [40..631] | [1..570] |
|
|
4.0E-98 | [21..606] | [764..1207] |
|
|
2.0E-78 | [10..247] | [20..242] |
|
|
6.0E-75 | [214..617] | [67..439] |
|
|
8.0E-67 | [224..629] | [575..957] |
|
|
2.0E-66 | [280..623] | [93..419] |
|
|
1.0E-63 | [287..585] | [494..759] |
|
|
2.0E-60 | [288..585] | [497..744] |
|
Region A: Residues: [1-226] |
1 11 21 31 41 51
| | | | | |
1 MELSSNLKDL YIEWLQELVD GLTPKQEQLK IAYEKAKRNL QNAEGSFYYP TDLKKVKGIG 60
61 NTIIKRLDTK LRNYCKIHHI SPVEAPSLTQ TSSTRPPKRT TTALRSIVNS CENDKNEAPE 120
121 EKGTKKRKTR KYIPKKRSGG YAILLSLLEL NAIPRGVSKE QIIEVAGKYS DHCMTPNFST 180
181 KEFYGAWSSI AALKKHSLVL EEGRPKRYSL TEEGVELTKS LKTADG
|
| Detection Method: |  |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
| Term | Confidence | Notes |
| DNA-directed DNA polymerase activity | 3.46780352518677 | bayes_pls_golite062009 |
| DNA polymerase activity | 3.42429084792579 | bayes_pls_golite062009 |
| nucleotidyltransferase activity | 1.8990253905448 | bayes_pls_golite062009 |
| catalytic activity | 0.585392957294978 | bayes_pls_golite062009 |
|
Region A: Residues: [227-334] |
1 11 21 31 41 51
| | | | | |
1 ISFPKENEEP NEYSVTRNES SEFTANLTDL RGEYGKEEEP CDINNTSFML DITFQDLSTP 60
61 QRLQNNVFKN DRLNSQTNIS SHKLEEVSDD QTVPDSALKA KSTIKRRR
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
SCOP Match |
SCOP Description | ||
| View | Download | 0.336 | a.74.1 | Cyclin-like |
| View | Download | 0.207 | a.70.1 | N-terminal domain of the delta subunit of the F1F0-ATP synthase |
| View | Download | 0.200 | a.118.1 | ARM repeat |
|
Region A: Residues: [335-454] |
1 11 21 31 41 51
| | | | | |
1 YNGVSYELWC SGDFEVFPII DHREIKSQSD REFFSRAFER KGMKSEIRQL ALGDIIWVAK 60
61 NKNTGLQCVL NTIVERKRLD DLALSIRDNR FMEQKNRLEK SGCEHKYYLI EETMSGNIGN 120
121
|
| Detection Method: | |
| Confidence: | 50.086186 |
| Match: | PF02732 |
| Description: | ERCC4 domain |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
| Term | Confidence | Notes |
| four-way junction helicase activity | 10.562254984301 | bayes_pls_golite062009 |
| DNA helicase activity | 7.81641089090703 | bayes_pls_golite062009 |
| endodeoxyribonuclease activity | 3.88121538069074 | bayes_pls_golite062009 |
| single-stranded DNA specific endodeoxyribonuclease activity | 3.87045877570028 | bayes_pls_golite062009 |
| deoxyribonuclease activity | 3.62965779224499 | bayes_pls_golite062009 |
| excinuclease ABC activity | 3.48615352002265 | bayes_pls_golite062009 |
| DNA binding | 2.97855002479178 | bayes_pls_golite062009 |
| structure-specific DNA binding | 2.83758378400856 | bayes_pls_golite062009 |
| nucleic acid binding | 2.79236389919005 | bayes_pls_golite062009 |
| single-stranded DNA binding | 2.79104877030658 | bayes_pls_golite062009 |
| damaged DNA binding | 2.3008149920351 | bayes_pls_golite062009 |
| helicase activity | 2.29491252701513 | bayes_pls_golite062009 |
| binding | 2.17324322139334 | bayes_pls_golite062009 |
| nuclease activity | 1.92659045080864 | bayes_pls_golite062009 |
| endonuclease activity | 1.7109181764667 | bayes_pls_golite062009 |
| DNA strand annealing activity | 1.5117854648336 | bayes_pls_golite062009 |
| pyrophosphatase activity | 1.02983374615445 | bayes_pls_golite062009 |
| hydrolase activity, acting on ester bonds | 1.02325715570644 | bayes_pls_golite062009 |
| catalytic activity | 0.816447099398022 | bayes_pls_golite062009 |
| double-stranded DNA binding | 0.73359455482295 | bayes_pls_golite062009 |
| protein binding | 0.71091195096997 | bayes_pls_golite062009 |
|
Region A: Residues: [455-632] |
1 11 21 31 41 51
| | | | | |
1 MNEALKTALW VILVYYKFSM IRTCNSDETV EKIHALHTVI SHHYSQKDLI VIFPSDLKSK 60
61 DDYKKVLLQF RREFERKGGI ECCHNLECFQ ELMGKGDLKT VGELTIHVLM LVKGISLEKA 120
121 VAIQEIFPTL NKILMAYKTC SSEEEAKLLM FNVLGDAPGA KKITKSLSEK IYDAFGKL
|
| Detection Method: | |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
| MCM Score |
GO Score |
GO Term |
SCOP Match |
SCOP Description | ||
| View | Download | 0.298 | 0.552 | reciprocal meiotic recombination | c.2.1 | NAD(P)-binding Rossmann-fold domains |
| View | Download | 0.248 | 0.030 | reciprocal meiotic recombination | a.118.8 | TPR-like |
| View | Download | 0.244 | 0.019 | reciprocal meiotic recombination | c.78.1 | Aspartate/ornithine carbamoyltransferase |
| View | Download | 0.318 | 0.006 | reciprocal meiotic recombination | a.126.1 | Serum albumin-like |
| View | Download | 0.244 | N/A | N/A | a.126.1 | Serum albumin-like |
| View | Download | 0.242 | N/A | N/A | c.17.1 | Caspase-like |
| View | Download | 0.234 | N/A | N/A | c.23.16 | Class I glutamine amidotransferase-like |
| View | Download | 0.231 | N/A | N/A | a.118.3 | Sec7 domain |
| View | Download | 0.226 | N/A | N/A | c.51.3 | B12-dependend dehydatases associated subunit |
| View | Download | 0.217 | N/A | N/A | c.36.1 | Thiamin diphosphate-binding fold (THDP-binding) |
| View | Download | 0.212 | N/A | N/A | a.39.1 | EF-hand |
| View | Download | 0.207 | N/A | N/A | c.23.13 | Type II 3-dehydroquinate dehydratase |
| View | Download | 0.204 | N/A | N/A | c.45.1 | (Phosphotyrosine protein) phosphatases II |
| View | Download | 0.201 | N/A | N/A | c.108.1 | HAD-like |
