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Protein Overview: gi|190404676

General Information:
Name(s) found: gi|190404676 [NCBI NR]
Description(s) found:
  • gi|190404676|gb|EDV07943.1| class II crossover junction endonuclease MUS81 [Saccharomyces cerevisiae RM11-1a] [NCBI NR]
    • Organism: Saccharomyces cerevisiae RM11-1a
    Length: 632 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MELSSNLKDL YIEWLQELVD GLTPKQEQLK IAYEKAKRNL QNAEGSFYYP TDLKKVKGIG  60
   61 NTIIKRLDTK LRNYCKIHHI SPVEAPSLTQ TSSTRPPKRT TTALRSIVNS CENDKNEAPE 120
  121 EKGTKKRKTR KYIPKKRSGG YAILLSLLEL NAIPRGVSKE QIIEVAGKYS DHCMTPNFST 180
  181 KEFYGAWSSI AALKKHSLVL EEGRPKRYSL TEEGVELTKS LKTADGISFP KENEEPNEYS 240
  241 VTRNESSEFT ANLTDLRGEY GKEEEPCDIN NTSFMLDITF QDLSTPQRLQ NNVFKNDRLN 300
  301 SQTNISSHKL EEVSDDQTVP DSALKAKSTI KRRRYNGVSY ELWCSGDFEV FPIIDHREIK 360
  361 SQSDREFFSR AFERKGMKSE IRQLALGDII WVAKNKNTGL QCVLNTIVER KRLDDLALSI 420
  421 RDNRFMEQKN RLEKSGCEHK YYLIEETMSG NIGNMNEALK TALWVILVYY KFSMIRTCNS 480
  481 DETVEKIHAL HTVISHHYSQ KDLIVIFPSD LKSKDDYKKV LLQFRREFER KGGIECCHNL 540
  541 ECFQELMGKG DLKTVGELTI HVLMLVKGIS LEKAVAIQEI FPTLNKILMA YKTCSSEEEA 600
  601 KLLMFNVLGD APGAKKITKS LSEKIYDAFG KL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..226] MSA 2.007945 View MSA. No confident structure predictions are available.
    2 View Details [227..334] deduced N/A No confident structure predictions are available.
    3 View Details [335..454] Pfam 50.086186 ERCC4 domain No confident structure predictions are available.
    4 View Details [455..632] MSA 3.038979 View MSA. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • DNA-directed DNA polymerase activity
    		•  3.46780352518677 bayes_pls_golite062009
  • DNA polymerase activity
    		•  3.42429084792579 bayes_pls_golite062009
  • nucleotidyltransferase activity
    		•  1.8990253905448 bayes_pls_golite062009
  • catalytic activity
    		•  0.585392957294978 bayes_pls_golite062009
    2 No functions predicted.
    3
    Term Confidence Notes
  • four-way junction helicase activity
    		•  10.562254984301 bayes_pls_golite062009
  • DNA helicase activity
    		•  7.81641089090703 bayes_pls_golite062009
  • endodeoxyribonuclease activity
    		•  3.88121538069074 bayes_pls_golite062009
  • single-stranded DNA specific endodeoxyribonuclease activity
    		•  3.87045877570028 bayes_pls_golite062009
  • deoxyribonuclease activity
    		•  3.62965779224499 bayes_pls_golite062009
  • excinuclease ABC activity
    		•  3.48615352002265 bayes_pls_golite062009
  • DNA binding
    		•  2.97855002479178 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  2.83758378400856 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.79236389919005 bayes_pls_golite062009
  • single-stranded DNA binding
    		•  2.79104877030658 bayes_pls_golite062009
  • damaged DNA binding
    		•  2.3008149920351 bayes_pls_golite062009
  • helicase activity
    		•  2.29491252701513 bayes_pls_golite062009
  • binding
    		•  2.17324322139334 bayes_pls_golite062009
  • nuclease activity
    		•  1.92659045080864 bayes_pls_golite062009
  • endonuclease activity
    		•  1.7109181764667 bayes_pls_golite062009
  • DNA strand annealing activity
    		•  1.5117854648336 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  1.02983374615445 bayes_pls_golite062009
  • hydrolase activity, acting on ester bonds
    		•  1.02325715570644 bayes_pls_golite062009
  • catalytic activity
    		•  0.816447099398022 bayes_pls_golite062009
  • double-stranded DNA binding
    		•  0.73359455482295 bayes_pls_golite062009
  • protein binding
    		•  0.71091195096997 bayes_pls_golite062009
    4 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle