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View Structure Prediction Details

Protein: YRA1
Organism: Saccharomyces cerevisiae
Length: 226 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YRA1.

Description E-value Query
Range		 Subject
Range
PABP1_BOVIN - Polyadenylate-binding protein 1 OS=Bos taurus GN=PABPC1 PE=2 SV=1
gi|109087089 - gi|109087089|ref|XP_001098239.1| PREDICTED: poly(A) binding protein, cytoplasmic 1 isoform 2 [Macaca...
gi|123993665, gi... - gi|168278070|dbj|BAG11013.1| polyadenylate-binding protein 1 [synthetic construct], gi|123999981|gb|...
gi|194036975 - gi|194036975|ref|XP_001927782.1| PREDICTED: similar to Polyadenylate-binding protein 1 (Poly(A)-bind...
PABPC1 - poly(A) binding protein, cytoplasmic 1
gi|73974130, gi|... - gi|73974178|ref|XP_857695.1| PREDICTED: similar to Polyadenylate-binding protein 1 (Poly(A)-binding ...
 6.0E-56 [1..211] [210..429]
PABP1_MOUSE - Polyadenylate-binding protein 1 OS=Mus musculus GN=Pabpc1 PE=1 SV=2
 7.0E-56 [1..211] [210..429]
PABP1_RAT - Polyadenylate-binding protein 1 OS=Rattus norvegicus GN=Pabpc1 PE=1 SV=1
 7.0E-56 [1..211] [210..429]
gi|19526272 - gi|19526272|gb|AAL89666.1|AF411956_7 polyA-binding protein [Takifugu rubripes]
 4.0E-54 [1..211] [210..428]
PABP8_ARATH - Polyadenylate-binding protein 8 OS=Arabidopsis thaliana GN=PAB8 PE=1 SV=1
 4.0E-54 [2..203] [244..451]
gi|64970 - gi|64970|emb|CAA40721.1| polyA binding protein [Xenopus laevis]
 1.0E-53 [1..211] [210..427]
gi|13560783 - gi|13560783|gb|AAK30205.1|AF349964_1 poly(A)-binding protein [Daucus carota]
 8.0E-53 [2..203] [239..446]

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Predicted Domain #1
Region A:
Residues: [1-67] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSANLDKSLD EIIGSNKAGS NRARVGGTRG NGPRRVGKQV GSQRRSLPNR RGPIRKNTRA  60
   61 PPNAVAR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 46.154902
Match: 1l3kA_
Description: Nuclear ribonucleoprotein A1 (RNP A1, UP1)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
nucleic acid binding 4.51665560478175 bayes_pls_golite062009
binding 3.64400841800969 bayes_pls_golite062009
mRNA binding 3.27529715028622 bayes_pls_golite062009
RNA binding 2.92438188845619 bayes_pls_golite062009
transcription regulator activity 1.7776932219095 bayes_pls_golite062009
DNA binding 1.65208390030564 bayes_pls_golite062009
single-stranded DNA binding 1.44900283271761 bayes_pls_golite062009
structure-specific DNA binding 1.44189759422835 bayes_pls_golite062009
protein binding 1.12215421354121 bayes_pls_golite062009
mRNA 3'-UTR binding 0.824614388276642 bayes_pls_golite062009
structural molecule activity 0.815302976466241 bayes_pls_golite062009
transcription factor activity 0.795084003256395 bayes_pls_golite062009
transporter activity 0.628672636801176 bayes_pls_golite062009
translation regulator activity 0.583455818533482 bayes_pls_golite062009
transmembrane transporter activity 0.505106991526286 bayes_pls_golite062009
0.4921730944941 bayes_pls_golite062009
translation factor activity, nucleic acid binding 0.333822192939807 bayes_pls_golite062009
sequence-specific DNA binding 0.304235325881492 bayes_pls_golite062009
substrate-specific transporter activity 0.182749906784328 bayes_pls_golite062009
nucleoside-triphosphatase activity 0.096231856558874 bayes_pls_golite062009
pyrophosphatase activity 0.059732432409948 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides 0.0510390778764699 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 0.0484248928275733 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [68-226] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VAKLLDTTRE VKVNVEGLPR DIKQDAVREF FASQVGGVQR VLLSYNERGQ STGMANITFK  60
   61 NGELARRAVE RFNGSPIDGG RSRLRLNLIV DPNQRPVKSL ADRIKAMPQK GGNAPRPVKR 120
  121 GPNRKAAMAK SQNKPKREKP AKKSLEDLDK EMADYFEKK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 46.154902
Match: 1l3kA_
Description: Nuclear ribonucleoprotein A1 (RNP A1, UP1)
Matching Structure (courtesy of the PDB):
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle