| Protein: | GIS1 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 894 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GIS1.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..894] | [1..894] |
|
|
0.0 | [247..893] | [359..1056] |
|
|
0.0 | [299..893] | [244..826] |
|
|
0.0 | [335..893] | [16..628] |
|
Region A: Residues: [1-79] |
1 11 21 31 41 51
| | | | | |
1 MEIKPVEVID GVPVFKPSMM EFANFQYFID EITKFGIENG IVKVIPPKEW LELLEGSPPA 60
61 ESLKTIQLDS PIQQQAKRW
|
| Detection Method: |  |
| Confidence: | 28.508638 |
| Match: | PF02375 |
| Description: | jmjN domain |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [80-136] |
1 11 21 31 41 51
| | | | | |
1 DKHENGVFSI ENEYDNKSYN LTQWKNLAES LDSRISQGDF NDKTLKENCR VDSQQDC
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [137-307] |
1 11 21 31 41 51
| | | | | |
1 YDLAQLQILE SDFWKTIAFS KPFYAVDENS SIFPYDLTLW NLNNLPDSIN SSNRRLLTGQ 60
61 SKCIFPWHLD EQNKCSINYL HFGAPKQWYS IPSANTDQFL KILSKEPSSN KENCPAFIRH 120
121 QNIITSPDFL RKNNIKFNRV VQFQHEFIIT FPYCMYSGFN YGYNFGESIE F
|
| Detection Method: | |
| Confidence: | 50.327902 |
| Match: | PF02373 |
| Description: | JmjC domain |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
| Term | Confidence | Notes |
| nucleic acid binding | 2.97176528779183 | bayes_pls_golite062009 |
| binding | 2.95955830245165 | bayes_pls_golite062009 |
| DNA binding | 2.78082210591574 | bayes_pls_golite062009 |
| transcription regulator activity | 2.53889200428466 | bayes_pls_golite062009 |
| chromatin binding | 2.17816148863289 | bayes_pls_golite062009 |
| transcription factor activity | 1.71320052881408 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity | 1.03479741823043 | bayes_pls_golite062009 |
| protein binding | 1.02778071153188 | bayes_pls_golite062009 |
| transcription activator activity | 0.90850120023053 | bayes_pls_golite062009 |
| histone binding | 0.687710658383448 | bayes_pls_golite062009 |
| transcription repressor activity | 0.373557406294709 | bayes_pls_golite062009 |
| catalytic activity | 0.245893663605433 | bayes_pls_golite062009 |
| sequence-specific DNA binding | 0.2354474590082 | bayes_pls_golite062009 |
| transcription factor binding | 0.1746219785248 | bayes_pls_golite062009 |
|
Region A: Residues: [308-395] |
1 11 21 31 41 51
| | | | | |
1 ILDQQAVVRK QPLKCGCGNK KEERKSGPFS NLSYDSNESE QRGSITDNDN DLFQKVRSFD 60
61 ELLNHSSQEL QNLEDNKNPL FSNINMNR
|
| Detection Method: | |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [396-465] |
1 11 21 31 41 51
| | | | | |
1 PQSSSLRSTT PNGVNQFLNM NQTTISRISS PLLSRMMDLS NIVEPTLDDP GSKFKRKVLT 60
61 PQLPQMNIPS
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [466-615] |
1 11 21 31 41 51
| | | | | |
1 NSSNFGTPSL TNTNSLLSNI TATSTNPSTT TNGSQNHNNV NANGINTSAA ASINNNISST 60
61 NNSANNSSSN NNVSTVPSSM MHSSTLNGTS GLGGDNDDNM LALSLATLAN SATASPRLTL 120
121 PPLSSPMNPN GHTSYNGNMM NNNSGNGSNG
|
| Detection Method: | |
| Confidence: | 17.69897 |
| Match: | 2gliA_ |
| Description: | Five-finger GLI1 |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [616-694] |
1 11 21 31 41 51
| | | | | |
1 SNSYSNGVTT AAATTTSAPH NLSIVSPNPT YSPNPLSLYL TNSKNPLNSG LAPLSPSTSN 60
61 IPFLKRNNVV TLNISREAS
|
| Detection Method: | |
| Confidence: | 89.24799 |
| Match: | 1a1iA_ |
| Description: | ZIF268 |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [695-775] |
1 11 21 31 41 51
| | | | | |
1 KSPISSFVND YRSPLGVSNP LMYSSTINDY SNGTGIRQNS NNINPLDAGP SFSPLHKKPK 60
61 ILNGNDNSNL DSNNFDYSFT G
|
| Detection Method: | |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [776-848] |
1 11 21 31 41 51
| | | | | |
1 NKQESNPSIL NNNTNNNDNY RTSSMNNNGN NYQAHSSKFG ENEVIMSDHG KIYICRECNR 60
61 QFSSGHHLTR HKK
|
| Detection Method: | |
| Confidence: | 2.69897 |
| Match: | 2drpA_ |
| Description: | Tramtrack protein (two zinc-finger peptide) |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [849-894] |
1 11 21 31 41 51
| | | | | |
1 SVHSGEKPHS CPRCGKRFKR RDHVLQHLNK KIPCTQEMEN TKLAES
|
| Detection Method: | |
| Confidence: | 78.30103 |
| Match: | 2adr__ |
| Description: | ADR1 |
Matching Structure (courtesy of the PDB): |
|
