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Protein Overview: GIS1_YEAST

General Information:
Name(s) found: GIS1_YEAST [Swiss-Prot]
Description(s) found:
  • Transcriptional activator/repressor GIS1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=GIS1 PE=1 SV=1 [Swiss-Prot]
    • Organism: Saccharomyces cerevisiae S288c
    Length: 894 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEIKPVEVID GVPVFKPSMM EFANFQYFID EITKFGIENG IVKVIPPKEW LELLEGSPPA  60
   61 ESLKTIQLDS PIQQQAKRWD KHENGVFSIE NEYDNKSYNL TQWKNLAESL DSRISQGDFN 120
  121 DKTLKENCRV DSQQDCYDLA QLQILESDFW KTIAFSKPFY AVDENSSIFP YDLTLWNLNN 180
  181 LPDSINSSNR RLLTGQSKCI FPWHLDEQNK CSINYLHFGA PKQWYSIPSA NTDQFLKILS 240
  241 KEPSSNKENC PAFIRHQNII TSPDFLRKNN IKFNRVVQFQ HEFIITFPYC MYSGFNYGYN 300
  301 FGESIEFILD QQAVVRKQPL KCGCGNKKEE RKSGPFSNLS YDSNESEQRG SITDNDNDLF 360
  361 QKVRSFDELL NHSSQELQNL EDNKNPLFSN INMNRPQSSS LRSTTPNGVN QFLNMNQTTI 420
  421 SRISSPLLSR MMDLSNIVEP TLDDPGSKFK RKVLTPQLPQ MNIPSNSSNF GTPSLTNTNS 480
  481 LLSNITATST NPSTTTNGSQ NHNNVNANGI NTSAAASINN NISSTNNSAN NSSSNNNVST 540
  541 VPSSMMHSST LNGTSGLGGD NDDNMLALSL ATLANSATAS PRLTLPPLSS PMNPNGHTSY 600
  601 NGNMMNNNSG NGSNGSNSYS NGVTTAAATT TSAPHNLSIV SPNPTYSPNP LSLYLTNSKN 660
  661 PLNSGLAPLS PSTSNIPFLK RNNVVTLNIS REASKSPISS FVNDYRSPLG VSNPLMYSST 720
  721 INDYSNGTGI RQNSNNINPL DAGPSFSPLH KKPKILNGND NSNLDSNNFD YSFTGNKQES 780
  781 NPSILNNNTN NNDNYRTSSM NNNGNNYQAH SSKFGENEVI MSDHGKIYIC RECNRQFSSG 840
  841 HHLTRHKKSV HSGEKPHSCP RCGKRFKRRD HVLQHLNKKI PCTQEMENTK LAES

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..79] Pfam 28.508638 jmjN domain No confident structure predictions are available.
    2 View Details [80..136] deduced N/A No confident structure predictions are available.
    3 View Details [137..307] Pfam 50.327902 JmjC domain No confident structure predictions are available.
    4 View Details [308..395] MSA 19.514997 View MSA. No confident structure predictions are available.
    5 View Details [396..465] deduced N/A No confident structure predictions are available.
    6 View Details [466..615] PSI-BLAST 17.69897 Five-finger GLI1
    7 View Details [616..694] PSI-BLAST 89.24799 ZIF268
    8 View Details [695..775] MSA 13.281994 View MSA. No confident structure predictions are available.
    9 View Details [776..848] PSI-BLAST 2.69897 Tramtrack protein (two zinc-finger peptide)
    10 View Details [849..894] PSI-BLAST 78.30103 ADR1

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3
    Term Confidence Notes
  • nucleic acid binding
    		•  2.97176528779183 bayes_pls_golite062009
  • binding
    		•  2.95955830245165 bayes_pls_golite062009
  • DNA binding
    		•  2.78082210591574 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.53889200428466 bayes_pls_golite062009
  • chromatin binding
    		•  2.17816148863289 bayes_pls_golite062009
  • transcription factor activity
    		•  1.71320052881408 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  1.03479741823043 bayes_pls_golite062009
  • protein binding
    		•  1.02778071153188 bayes_pls_golite062009
  • transcription activator activity
    		•  0.90850120023053 bayes_pls_golite062009
  • histone binding
    		•  0.687710658383448 bayes_pls_golite062009
  • transcription repressor activity
    		•  0.373557406294709 bayes_pls_golite062009
  • catalytic activity
    		•  0.245893663605433 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  0.2354474590082 bayes_pls_golite062009
  • transcription factor binding
    		•  0.1746219785248 bayes_pls_golite062009
    4 No functions predicted.
    5 No functions predicted.
    6 No functions predicted.
    7 No functions predicted.
    8 No functions predicted.
    9 No functions predicted.
    10 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle