| Protein: | LRG1 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 1017 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for LRG1.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..1017] | [1..1017] |
|
|
0.0 | [9..968] | [97..1053] |
|
|
3.0E-95 | [512..1011] | [136..602] |
|
|
4.0E-87 | [514..1005] | [139..593] |
|
|
9.0E-86 | [522..1009] | [1423..1922] |
|
Region A: Residues: [1-93] |
1 11 21 31 41 51
| | | | | |
1 MIQNSAGYRS LNTASPMTVQ VKNQKKICAR CNKLVIPDSQ RTKTTLKALG KYYHESCFTC 60
61 QDCQKPLKPK YFPYQVDKTS ESILLCQYDY FRR
|
| Detection Method: |  |
| Confidence: | 10.30103 |
| Match: | 1b8tA_ |
| Description: | Cysteine-rich (intestinal) protein, CRP, CRIP |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| binding | 2.96409924710655 | bayes_pls_golite062009 |
| transcription regulator activity | 2.22839475692516 | bayes_pls_golite062009 |
| DNA binding | 1.96428761552366 | bayes_pls_golite062009 |
| molecular transducer activity | 1.86972157198727 | bayes_pls_golite062009 |
| signal transducer activity | 1.86972157198727 | bayes_pls_golite062009 |
| receptor activity | 1.84800188265901 | bayes_pls_golite062009 |
| nucleic acid binding | 1.73351698570585 | bayes_pls_golite062009 |
| transcription factor activity | 1.41077905480556 | bayes_pls_golite062009 |
| protein binding | 1.39455913713025 | bayes_pls_golite062009 |
| transporter activity | 0.883869495141753 | bayes_pls_golite062009 |
| transmembrane transporter activity | 0.69816175939074 | bayes_pls_golite062009 |
| sequence-specific DNA binding | 0.6267176811988 | bayes_pls_golite062009 |
| ligand-dependent nuclear receptor activity | 0.55799224325565 | bayes_pls_golite062009 |
| transcription activator activity | 0.53223427184258 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 0.480921069521595 | bayes_pls_golite062009 |
| transcription factor binding | 0.43597775400036 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity | 0.30102391671156 | bayes_pls_golite062009 |
| substrate-specific transmembrane transporter activity | 0.248246733554633 | bayes_pls_golite062009 |
| general RNA polymerase II transcription factor activity | 0.14923328147546 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 0.110294001412626 | bayes_pls_golite062009 |
| actin binding | 0.0158809112602751 | bayes_pls_golite062009 |
|
Region A: Residues: [94-210] |
1 11 21 31 41 51
| | | | | |
1 HNLLCHVCDT PLRGLYYTAF GYRYDEEHFS CTICATPCGV KKCFMYGNQL YCKYHFLKYF 60
61 SKRCKGCEFP ISDQYIEFPK GEEIHCWHPE CYGIHKYWHV NLAAETVGLQ YLPKLEY
|
| Detection Method: | |
| Confidence: | 10.30103 |
| Match: | 1b8tA_ |
| Description: | Cysteine-rich (intestinal) protein, CRP, CRIP |
| Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [211-298] |
1 11 21 31 41 51
| | | | | |
1 NPNSGDKDIN PTAYELDKQM QAFNFILSKT WSVLYRFEEE AASCISDMFQ YLTSNDQLKG 60
61 IESTGLLVLK IDCLFRGLDT LNLSTNKS
|
| Detection Method: | |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
| MCM Score |
GO Score |
GO Term |
SCOP Match |
SCOP Description | ||
| View | Download | 0.924 | 0.199 | Rho GTPase activator activity | a.45.1 | Glutathione S-transferase (GST), C-terminal domain |
| View | Download | 0.931 | 0.024 | Rho GTPase activator activity | a.47.2 | t-snare proteins |
| View | Download | 0.960 | 0.021 | Rho GTPase activator activity | a.7.3 | Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain |
| View | Download | 0.906 | 0.004 | Rho GTPase activator activity | a.7.2 | Enzyme IIa from lactose specific PTS, IIa-lac |
| View | Download | 0.940 | N/A | N/A | a.23.1 | HSC20 (HSCB), C-terminal oligomerisation domain |
| View | Download | 0.879 | N/A | N/A | a.24.11 | Bacterial GAP domain |
| View | Download | 0.877 | N/A | N/A | a.7.8 | GAT domain |
| View | Download | 0.863 | N/A | N/A | a.27.1 | Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases |
| View | Download | 0.798 | N/A | N/A | a.7.6 | Ribosomal protein S20 |
| View | Download | 0.796 | N/A | N/A | a.27.1 | Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases |
| View | Download | 0.787 | N/A | N/A | a.7.7 | BAG domain |
| View | Download | 0.762 | N/A | N/A | a.45.1 | Glutathione S-transferase (GST), C-terminal domain |
| View | Download | 0.733 | N/A | N/A | a.46.1 | Methionine synthase domain |
| View | Download | 0.705 | N/A | N/A | a.2.2 | Ribosomal protein L29 (L29p) |
| View | Download | 0.698 | N/A | N/A | a.118.9 | ENTH/VHS domain |
| View | Download | 0.692 | N/A | N/A | a.7.1 | Spectrin repeat |
| View | Download | 0.689 | N/A | N/A | a.7.7 | BAG domain |
| View | Download | 0.652 | N/A | N/A | i.1.1 | Ribosome and ribosomal fragments |
| View | Download | 0.652 | N/A | N/A | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.634 | N/A | N/A | a.64.1 | Saposin |
| View | Download | 0.626 | N/A | N/A | a.118.1 | ARM repeat |
| View | Download | 0.615 | N/A | N/A | a.27.1 | Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases |
| View | Download | 0.590 | N/A | N/A | a.7.3 | Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain |
| View | Download | 0.568 | N/A | N/A | a.26.1 | 4-helical cytokines |
| View | Download | 0.556 | N/A | N/A | a.2.3 | Chaperone J-domain |
| View | Download | 0.555 | N/A | N/A | a.24.7 | FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) |
| View | Download | 0.549 | N/A | N/A | f.17.1 | F1F0 ATP synthase subunit C |
| View | Download | 0.546 | N/A | N/A | d.195.1 | YopH tyrosine phosphatase N-terminal domain |
| View | Download | 0.504 | N/A | N/A | a.2.7 | tRNA-binding arm |
| View | Download | 0.498 | N/A | N/A | a.5.6 | Hypothetical protein MTH1615 |
| View | Download | 0.489 | N/A | N/A | f.1.4 | Bcl-2 inhibitors of programmed cell death |
| View | Download | 0.486 | N/A | N/A | a.45.1 | Glutathione S-transferase (GST), C-terminal domain |
| View | Download | 0.480 | N/A | N/A | a.24.4 | Hemerythrin |
| View | Download | 0.475 | N/A | N/A | a.45.1 | Glutathione S-transferase (GST), C-terminal domain |
| View | Download | 0.474 | N/A | N/A | a.16.1 | S15/NS1 RNA-binding domain |
| View | Download | 0.472 | N/A | N/A | a.7.3 | Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain |
| View | Download | 0.470 | N/A | N/A | a.60.6 | DNA polymerase beta, N-terminal domain-like |
| View | Download | 0.468 | N/A | N/A | a.24.17 | Group V grass pollen allergen |
| View | Download | 0.459 | N/A | N/A | a.11.1 | Acyl-CoA binding protein |
| View | Download | 0.445 | N/A | N/A | a.17.1 | p8-MTCP1 |
| View | Download | 0.438 | N/A | N/A | a.8.2 | Plasmid maintenance system epsilon/zeta, antidote epsilon subunit |
| View | Download | 0.436 | N/A | N/A | f.1.4 | Bcl-2 inhibitors of programmed cell death |
| View | Download | 0.435 | N/A | N/A | a.52.1 | Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin |
| View | Download | 0.432 | N/A | N/A | a.118.8 | TPR-like |
| View | Download | 0.423 | N/A | N/A | a.118.1 | ARM repeat |
| View | Download | 0.417 | N/A | N/A | a.4.8 | Ribosomal protein S18 |
| View | Download | 0.397 | N/A | N/A | a.2.6 | Effector domain of the protein kinase pkn/prk1 |
| View | Download | 0.395 | N/A | N/A | a.2.8 | Eukaryotic DNA topoisomerase I, dispensable insert domain |
| View | Download | 0.395 | N/A | N/A | a.2.1 | GreA transcript cleavage protein, N-terminal domain |
| View | Download | 0.393 | N/A | N/A | a.29.2 | Bromodomain |
| View | Download | 0.389 | N/A | N/A | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.379 | N/A | N/A | f.15.1 | Small-conductance potassium channel |
| View | Download | 0.371 | N/A | N/A | a.24.11 | Bacterial GAP domain |
| View | Download | 0.371 | N/A | N/A | c.58.1 | Aminoacid dehydrogenase-like, N-terminal domain |
| View | Download | 0.367 | N/A | N/A | a.13.1 | alpha-2-Macroglobulin receptor associated protein (RAP) domain 1 |
| View | Download | 0.350 | N/A | N/A | f.14.1 | Voltage-gated potassium channels |
| View | Download | 0.343 | N/A | N/A | a.56.1 | CO dehydrogenase ISP C-domain like |
| View | Download | 0.337 | N/A | N/A | a.184.1 | TorA specific chaperone TorD |
| View | Download | 0.335 | N/A | N/A | a.60.9 | lambda integrase-like, N-terminal domain |
| View | Download | 0.334 | N/A | N/A | f.36.1 | Neurotransmitter-gated ion-channel pransmembrane pore |
| View | Download | 0.331 | N/A | N/A | a.3.1 | Cytochrome c |
| View | Download | 0.331 | N/A | N/A | a.7.1 | Spectrin repeat |
| View | Download | 0.318 | N/A | N/A | a.60.10 | Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain |
| View | Download | 0.317 | N/A | N/A | a.4.9 | Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 |
| View | Download | 0.308 | N/A | N/A | a.30.2 | Homodimeric domain of signal transducing histidine kinase |
| View | Download | 0.305 | N/A | N/A | a.159.1 | Protein serine/threonine phosphatase 2C, C-terminal domain |
| View | Download | 0.302 | N/A | N/A | a.69.3 | 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain |
| View | Download | 0.301 | N/A | N/A | a.52.1 | Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin |
| View | Download | 0.300 | N/A | N/A | a.118.8 | TPR-like |
| View | Download | 0.294 | N/A | N/A | a.51.1 | Cytochrome c oxidase subunit h |
| View | Download | 0.293 | N/A | N/A | d.95.2 | Homing endonucleases |
| View | Download | 0.286 | N/A | N/A | a.157.1 | Skp1 dimerisation domain-like |
| View | Download | 0.285 | N/A | N/A | a.61.1 | Retroviral matrix proteins |
| View | Download | 0.280 | N/A | N/A | a.118.11 | Cytochrome c oxidase subunit E |
| View | Download | 0.277 | N/A | N/A | a.71.2 | Helical domain of Sec23/24 |
| View | Download | 0.277 | N/A | N/A | a.112.1 | Description not found. |
| View | Download | 0.276 | N/A | N/A | a.61.1 | Retroviral matrix proteins |
| View | Download | 0.273 | N/A | N/A | a.24.10 | Histidine-containing phosphotransfer domain, HPT domain |
| View | Download | 0.270 | N/A | N/A | d.91.1 | N-terminal domain of eukaryotic peptide chain release factor subunit 1, ERF1 |
| View | Download | 0.269 | N/A | N/A | a.24.13 | Domain of the SRP/SRP receptor G-proteins |
| View | Download | 0.269 | N/A | N/A | a.7.1 | Spectrin repeat |
| View | Download | 0.267 | N/A | N/A | f.36.1 | Neurotransmitter-gated ion-channel pransmembrane pore |
| View | Download | 0.267 | N/A | N/A | a.26.1 | 4-helical cytokines |
| View | Download | 0.266 | N/A | N/A | a.130.1 | Chorismate mutase II |
| View | Download | 0.266 | N/A | N/A | a.26.1 | 4-helical cytokines |
| View | Download | 0.262 | N/A | N/A | a.71.1 | Endoplasmic reticulum protein ERP29, C-domain |
| View | Download | 0.257 | N/A | N/A | d.49.1 | Signal recognition particle alu RNA binding heterodimer, SRP9/14 |
| View | Download | 0.257 | N/A | N/A | a.45.1 | Glutathione S-transferase (GST), C-terminal domain |
| View | Download | 0.257 | N/A | N/A | a.52.1 | Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin |
| View | Download | 0.257 | N/A | N/A | a.29.4 | RecG, N-terminal domain |
| View | Download | 0.248 | N/A | N/A | a.45.1 | Glutathione S-transferase (GST), C-terminal domain |
| View | Download | 0.247 | N/A | N/A | a.146.1 | Telomeric repeat binding factor (TRF) dimerisation domain |
| View | Download | 0.246 | N/A | N/A | d.58.17 | Metal-binding domain |
| View | Download | 0.244 | N/A | N/A | a.52.1 | Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin |
| View | Download | 0.243 | N/A | N/A | a.100.1 | 6-phosphogluconate dehydrogenase C-terminal domain-like |
| View | Download | 0.242 | N/A | N/A | a.4.6 | C-terminal effector domain of the bipartite response regulators |
| View | Download | 0.240 | N/A | N/A | a.24.9 | alpha-catenin/vinculin |
| View | Download | 0.239 | N/A | N/A | a.90.1 | Transcription factor STAT-4 N-domain |
| View | Download | 0.237 | N/A | N/A | a.47.2 | t-snare proteins |
| View | Download | 0.235 | N/A | N/A | f.13.1 | Family A G protein-coupled receptor-like |
| View | Download | 0.232 | N/A | N/A | a.3.1 | Cytochrome c |
| View | Download | 0.231 | N/A | N/A | a.24.3 | Cytochromes |
| View | Download | 0.229 | N/A | N/A | a.77.1 | DEATH domain |
| View | Download | 0.228 | N/A | N/A | d.26.1 | FKBP-like |
| View | Download | 0.226 | N/A | N/A | a.61.1 | Retroviral matrix proteins |
| View | Download | 0.226 | N/A | N/A | a.59.1 | PAH2 domain |
| View | Download | 0.225 | N/A | N/A | a.24.12 | Outer surface protein C (OspC) |
| View | Download | 0.225 | N/A | N/A | a.7.1 | Spectrin repeat |
| View | Download | 0.224 | N/A | N/A | d.68.1 | Translation initiation factor IF3, C-terminal domain |
| View | Download | 0.223 | N/A | N/A | a.26.1 | 4-helical cytokines |
| View | Download | 0.221 | N/A | N/A | d.8.1 | Urease, gamma-subunit |
| View | Download | 0.221 | N/A | N/A | d.58.39 | Glutamyl tRNA-reductase catalytic, N-terminal domain |
| View | Download | 0.221 | N/A | N/A | a.156.1 | S13-like H2TH domain |
| View | Download | 0.220 | N/A | N/A | a.74.1 | Cyclin-like |
| View | Download | 0.216 | N/A | N/A | a.35.1 | lambda repressor-like DNA-binding domains |
| View | Download | 0.213 | N/A | N/A | d.43.1 | Elongation factor Ts (EF-Ts), dimerisation domain |
| View | Download | 0.211 | N/A | N/A | f.1.3 | delta-Endotoxin (insectocide), N-terminal domain |
| View | Download | 0.209 | N/A | N/A | a.4.6 | C-terminal effector domain of the bipartite response regulators |
| View | Download | 0.207 | N/A | N/A | d.141.1 | Ribosomal protein L6 |
| View | Download | 0.207 | N/A | N/A | d.58.18 | Regulatory domain in the aminoacid metabolism |
| View | Download | 0.206 | N/A | N/A | a.118.13 | Arp2/3 complex 16 kDa subunit ARPC5 |
| View | Download | 0.203 | N/A | N/A | a.2.7 | tRNA-binding arm |
| View | Download | 0.202 | N/A | N/A | a.39.1 | EF-hand |
| View | Download | 0.201 | N/A | N/A | a.4.6 | C-terminal effector domain of the bipartite response regulators |
|
Region A: Residues: [299-410] |
1 11 21 31 41 51
| | | | | |
1 MPVNSDQECI ENNAMAASKY SKFPKNLSTK IMIYLQLLRK LGTENKNETI TISSFMSVIT 60
61 GLAHFLKLLT RFGLYTALEN NKLTHSVNPL LRFLREVEKN ELFENNPFQY IK
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
GO Score |
GO Term |
SCOP Match |
SCOP Description | ||
| View | Download | 0.885 | 0.025 | Rho GTPase activator activity | a.45.1 | Glutathione S-transferase (GST), C-terminal domain |
| View | Download | 0.915 | 0.025 | Rho GTPase activator activity | a.24.3 | Cytochromes |
| View | Download | 0.951 | 0.025 | Rho GTPase activator activity | a.47.2 | t-snare proteins |
| View | Download | 0.919 | 0.025 | Rho GTPase activator activity | a.24.14 | FAT domain of focal adhesion kinase |
| View | Download | 0.927 | 0.025 | Rho GTPase activator activity | a.7.2 | Enzyme IIa from lactose specific PTS, IIa-lac |
| View | Download | 0.868 | 0.025 | Rho GTPase activator activity | f.1.3 | delta-Endotoxin (insectocide), N-terminal domain |
| View | Download | 0.850 | 0.025 | Rho GTPase activator activity | a.47.2 | t-snare proteins |
| View | Download | 0.846 | 0.025 | Rho GTPase activator activity | a.45.1 | Glutathione S-transferase (GST), C-terminal domain |
| View | Download | 0.839 | 0.025 | Rho GTPase activator activity | f.14.1 | Voltage-gated potassium channels |
| View | Download | 0.825 | 0.025 | Rho GTPase activator activity | a.7.7 | BAG domain |
| View | Download | 0.821 | 0.025 | Rho GTPase activator activity | a.2.8 | Eukaryotic DNA topoisomerase I, dispensable insert domain |
| View | Download | 0.818 | 0.025 | Rho GTPase activator activity | a.47.2 | t-snare proteins |
| View | Download | 0.816 | 0.025 | Rho GTPase activator activity | a.29.3 | Acyl-CoA dehydrogenase C-terminal domain-like |
| View | Download | 0.805 | 0.025 | Rho GTPase activator activity | a.7.8 | GAT domain |
| View | Download | 0.800 | 0.025 | Rho GTPase activator activity | a.7.7 | BAG domain |
| View | Download | 0.796 | 0.025 | Rho GTPase activator activity | a.24.9 | alpha-catenin/vinculin |
| View | Download | 0.792 | 0.025 | Rho GTPase activator activity | a.48.2 | Transferrin receptor ectodomain, C-terminal domain |
| View | Download | 0.782 | 0.025 | Rho GTPase activator activity | a.63.1 | Apolipophorin-III |
| View | Download | 0.769 | 0.025 | Rho GTPase activator activity | a.24.3 | Cytochromes |
| View | Download | 0.768 | 0.025 | Rho GTPase activator activity | a.24.9 | alpha-catenin/vinculin |
| View | Download | 0.739 | 0.025 | Rho GTPase activator activity | f.1.3 | delta-Endotoxin (insectocide), N-terminal domain |
| View | Download | 0.734 | 0.025 | Rho GTPase activator activity | a.45.1 | Glutathione S-transferase (GST), C-terminal domain |
| View | Download | 0.701 | 0.025 | Rho GTPase activator activity | f.36.1 | Neurotransmitter-gated ion-channel pransmembrane pore |
| View | Download | 0.690 | 0.025 | Rho GTPase activator activity | a.80.1 | DNA polymerase III clamp loader subunits, C-terminal domain |
| View | Download | 0.661 | 0.025 | Rho GTPase activator activity | a.7.1 | Spectrin repeat |
| View | Download | 0.638 | 0.025 | Rho GTPase activator activity | a.7.3 | Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain |
| View | Download | 0.637 | 0.025 | Rho GTPase activator activity | a.2.11 | Fe,Mn superoxide dismutase (SOD), N-terminal domain |
| View | Download | 0.634 | 0.025 | Rho GTPase activator activity | a.7.1 | Spectrin repeat |
| View | Download | 0.634 | 0.025 | Rho GTPase activator activity | a.24.1 | Apolipoprotein |
| View | Download | 0.632 | 0.025 | Rho GTPase activator activity | a.23.1 | HSC20 (HSCB), C-terminal oligomerisation domain |
| View | Download | 0.619 | 0.025 | Rho GTPase activator activity | a.26.1 | 4-helical cytokines |
| View | Download | 0.617 | 0.025 | Rho GTPase activator activity | a.48.1 | N-terminal domain of cbl (N-cbl) |
| View | Download | 0.615 | 0.025 | Rho GTPase activator activity | a.13.1 | alpha-2-Macroglobulin receptor associated protein (RAP) domain 1 |
| View | Download | 0.613 | 0.025 | Rho GTPase activator activity | a.2.7 | tRNA-binding arm |
| View | Download | 0.598 | 0.025 | Rho GTPase activator activity | a.29.5 | alpha-ketoacid dehydrogenase kinase, N-terminal domain |
| View | Download | 0.597 | 0.025 | Rho GTPase activator activity | a.29.5 | alpha-ketoacid dehydrogenase kinase, N-terminal domain |
| View | Download | 0.597 | 0.025 | Rho GTPase activator activity | a.7.1 | Spectrin repeat |
| View | Download | 0.593 | 0.025 | Rho GTPase activator activity | a.7.5 | Tubulin chaperone cofactor A |
| View | Download | 0.585 | 0.025 | Rho GTPase activator activity | i.1.1 | Ribosome and ribosomal fragments |
| View | Download | 0.585 | 0.025 | Rho GTPase activator activity | a.62.1 | Hepatitis B viral capsid (hbcag) |
| View | Download | 0.559 | 0.025 | Rho GTPase activator activity | a.2.1 | GreA transcript cleavage protein, N-terminal domain |
| View | Download | 0.555 | 0.025 | Rho GTPase activator activity | a.71.2 | Helical domain of Sec23/24 |
| View | Download | 0.537 | 0.025 | Rho GTPase activator activity | a.7.6 | Ribosomal protein S20 |
| View | Download | 0.534 | 0.025 | Rho GTPase activator activity | a.7.3 | Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain |
| View | Download | 0.504 | 0.025 | Rho GTPase activator activity | i.11.1 | Computational models partly based on NMR data |
| View | Download | 0.501 | 0.025 | Rho GTPase activator activity | f.36.1 | Neurotransmitter-gated ion-channel pransmembrane pore |
| View | Download | 0.500 | 0.025 | Rho GTPase activator activity | a.27.1 | Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases |
| View | Download | 0.492 | 0.025 | Rho GTPase activator activity | a.24.4 | Hemerythrin |
| View | Download | 0.492 | 0.025 | Rho GTPase activator activity | f.15.1 | Small-conductance potassium channel |
| View | Download | 0.479 | 0.025 | Rho GTPase activator activity | a.27.1 | Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases |
| View | Download | 0.456 | 0.025 | Rho GTPase activator activity | a.24.12 | Outer surface protein C (OspC) |
| View | Download | 0.450 | 0.025 | Rho GTPase activator activity | a.24.3 | Cytochromes |
| View | Download | 0.444 | 0.025 | Rho GTPase activator activity | a.24.16 | Nucleotidyltransferase substrate binding subunit/domain |
| View | Download | 0.436 | 0.025 | Rho GTPase activator activity | a.26.1 | 4-helical cytokines |
| View | Download | 0.432 | 0.025 | Rho GTPase activator activity | a.7.1 | Spectrin repeat |
| View | Download | 0.429 | 0.025 | Rho GTPase activator activity | a.26.1 | 4-helical cytokines |
| View | Download | 0.419 | 0.025 | Rho GTPase activator activity | f.34.1 | Mechanosensitive channel protein MscS (YggB), transmembrane region |
| View | Download | 0.419 | 0.025 | Rho GTPase activator activity | a.8.2 | Plasmid maintenance system epsilon/zeta, antidote epsilon subunit |
| View | Download | 0.417 | 0.025 | Rho GTPase activator activity | a.100.1 | 6-phosphogluconate dehydrogenase C-terminal domain-like |
| View | Download | 0.406 | 0.025 | Rho GTPase activator activity | a.30.2 | Homodimeric domain of signal transducing histidine kinase |
| View | Download | 0.403 | 0.025 | Rho GTPase activator activity | a.29.4 | RecG, N-terminal domain |
| View | Download | 0.403 | 0.025 | Rho GTPase activator activity | a.24.2 | Aspartate receptor, ligand-binding domain |
| View | Download | 0.400 | 0.025 | Rho GTPase activator activity | f.25.1 | Cytochrome c oxidase subunit III-like |
| View | Download | 0.399 | 0.025 | Rho GTPase activator activity | a.26.1 | 4-helical cytokines |
| View | Download | 0.398 | 0.025 | Rho GTPase activator activity | a.27.1 | Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases |
| View | Download | 0.396 | 0.025 | Rho GTPase activator activity | a.29.2 | Bromodomain |
| View | Download | 0.388 | 0.025 | Rho GTPase activator activity | a.29.2 | Bromodomain |
| View | Download | 0.382 | 0.025 | Rho GTPase activator activity | a.118.16 | Testis/brain RNA-binding protein (TB-RBP) |
| View | Download | 0.380 | 0.025 | Rho GTPase activator activity | a.2.3 | Chaperone J-domain |
| View | Download | 0.373 | 0.025 | Rho GTPase activator activity | a.45.1 | Glutathione S-transferase (GST), C-terminal domain |
| View | Download | 0.361 | 0.025 | Rho GTPase activator activity | a.24.10 | Histidine-containing phosphotransfer domain, HPT domain |
| View | Download | 0.361 | 0.025 | Rho GTPase activator activity | a.90.1 | Transcription factor STAT-4 N-domain |
| View | Download | 0.358 | 0.025 | Rho GTPase activator activity | a.29.2 | Bromodomain |
| View | Download | 0.353 | 0.025 | Rho GTPase activator activity | a.118.8 | TPR-like |
| View | Download | 0.348 | 0.025 | Rho GTPase activator activity | a.29.3 | Acyl-CoA dehydrogenase C-terminal domain-like |
| View | Download | 0.341 | 0.025 | Rho GTPase activator activity | a.2.5 | Prefoldin |
| View | Download | 0.336 | 0.025 | Rho GTPase activator activity | a.47.2 | t-snare proteins |
| View | Download | 0.335 | 0.025 | Rho GTPase activator activity | a.26.1 | 4-helical cytokines |
| View | Download | 0.330 | 0.025 | Rho GTPase activator activity | a.30.1 | ROP protein |
| View | Download | 0.311 | 0.025 | Rho GTPase activator activity | a.45.1 | Glutathione S-transferase (GST), C-terminal domain |
| View | Download | 0.311 | 0.025 | Rho GTPase activator activity | a.63.1 | Apolipophorin-III |
| View | Download | 0.302 | 0.025 | Rho GTPase activator activity | a.24.11 | Bacterial GAP domain |
| View | Download | 0.296 | 0.025 | Rho GTPase activator activity | a.2.7 | tRNA-binding arm |
| View | Download | 0.295 | 0.025 | Rho GTPase activator activity | a.1.1 | Globin-like |
| View | Download | 0.294 | 0.025 | Rho GTPase activator activity | a.29.2 | Bromodomain |
| View | Download | 0.291 | 0.025 | Rho GTPase activator activity | c.47.1 | Thioredoxin-like |
| View | Download | 0.285 | 0.025 | Rho GTPase activator activity | a.7.3 | Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain |
| View | Download | 0.280 | 0.025 | Rho GTPase activator activity | a.24.17 | Group V grass pollen allergen |
| View | Download | 0.275 | 0.025 | Rho GTPase activator activity | a.26.1 | 4-helical cytokines |
| View | Download | 0.274 | 0.025 | Rho GTPase activator activity | a.8.3 | Families 57/38 glycoside transferase middle domain |
| View | Download | 0.271 | 0.025 | Rho GTPase activator activity | a.24.9 | alpha-catenin/vinculin |
| View | Download | 0.269 | 0.025 | Rho GTPase activator activity | a.24.3 | Cytochromes |
| View | Download | 0.265 | 0.025 | Rho GTPase activator activity | a.118.7 | 14-3-3 protein |
| View | Download | 0.261 | 0.025 | Rho GTPase activator activity | a.74.1 | Cyclin-like |
| View | Download | 0.255 | 0.025 | Rho GTPase activator activity | a.78.1 | Fatty acid responsive transcription factor FadR, C-terminal domain |
| View | Download | 0.252 | 0.025 | Rho GTPase activator activity | f.21.2 | Fumarate reductase respiratory complex transmembrane subunits |
| View | Download | 0.250 | 0.025 | Rho GTPase activator activity | a.25.1 | Ferritin-like |
| View | Download | 0.248 | 0.025 | Rho GTPase activator activity | a.80.1 | DNA polymerase III clamp loader subunits, C-terminal domain |
| View | Download | 0.240 | 0.025 | Rho GTPase activator activity | d.96.1 | Tetrahydrobiopterin biosynthesis enzymes-like |
| View | Download | 0.238 | 0.025 | Rho GTPase activator activity | a.72.1 | Functional domain of the splicing factor Prp18 |
| View | Download | 0.238 | 0.025 | Rho GTPase activator activity | a.58.1 | Chemotaxis receptor methyltransferase CheR, N-terminal domain |
| View | Download | 0.236 | 0.025 | Rho GTPase activator activity | a.121.1 | Tetracyclin repressor-like, C-terminal domain |
| View | Download | 0.233 | 0.025 | Rho GTPase activator activity | a.25.1 | Ferritin-like |
| View | Download | 0.233 | 0.025 | Rho GTPase activator activity | a.25.1 | Ferritin-like |
| View | Download | 0.233 | 0.025 | Rho GTPase activator activity | a.25.2 | Thermoplasma ferritin-like 4-helical bundle |
| View | Download | 0.225 | 0.025 | Rho GTPase activator activity | c.55.6 | DNA repair protein MutS, domain II |
| View | Download | 0.218 | 0.025 | Rho GTPase activator activity | a.80.1 | DNA polymerase III clamp loader subunits, C-terminal domain |
| View | Download | 0.214 | 0.025 | Rho GTPase activator activity | f.31.1 | Photosystem I reaction center subunit XI, PsaL |
| View | Download | 0.211 | 0.025 | Rho GTPase activator activity | a.4.6 | C-terminal effector domain of the bipartite response regulators |
| View | Download | 0.208 | 0.025 | Rho GTPase activator activity | f.17.2 | Cytochrome c oxidase subunit II-like, transmembrane region |
| View | Download | 0.207 | 0.025 | Rho GTPase activator activity | a.24.15 | FAD-dependent thiol oxidase |
| View | Download | 0.202 | 0.025 | Rho GTPase activator activity | a.24.16 | Nucleotidyltransferase substrate binding subunit/domain |
| View | Download | 0.201 | 0.025 | Rho GTPase activator activity | a.27.1 | Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases |
|
Region A: Residues: [411-482] |
1 11 21 31 41 51
| | | | | |
1 TPVNATDSCA GCNKYIQEEC IQFYEHRWHI ACFTCSSCHK NINPRSLTDP TFNKEKKKIL 60
61 CSHCSIDDPA SV
|
| Detection Method: | |
| Confidence: | 15.431798 |
| Match: | PF00412 |
| Description: | LIM domain |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
|
Region A: Residues: [483-653] |
1 11 21 31 41 51
| | | | | |
1 PGFKFVTKLA QLIFLLKIAL VKSRTVMLKS KASNKVGRNS LQSTMLKEHT YIRTLNDIKR 60
61 LRSRRESVRV THNKQQARKS VILETAETDL NDPTKQGDSK NLVIQTDDPS SSQQVSTREN 120
121 VFSNTKTLTL DDISRIVAAE QARELRPNAF AHFKKLKETD DETSNVVPKK S
|
| Detection Method: | |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
| MCM Score |
GO Score |
GO Term |
SCOP Match |
SCOP Description | ||
| View | Download | 0.400 | 0.139 | Rho GTPase activator activity | a.25.1 | Ferritin-like |
| View | Download | 0.618 | 0.049 | Rho GTPase activator activity | a.29.3 | Acyl-CoA dehydrogenase C-terminal domain-like |
| View | Download | 0.665 | 0.039 | Rho GTPase activator activity | a.47.2 | t-snare proteins |
| View | Download | 0.410 | 0.008 | Rho GTPase activator activity | f.15.1 | Small-conductance potassium channel |
| View | Download | 0.439 | N/A | N/A | a.29.3 | Acyl-CoA dehydrogenase C-terminal domain-like |
| View | Download | 0.395 | N/A | N/A | a.25.1 | Ferritin-like |
| View | Download | 0.378 | N/A | N/A | a.25.1 | Ferritin-like |
| View | Download | 0.370 | N/A | N/A | a.24.3 | Cytochromes |
| View | Download | 0.334 | N/A | N/A | a.24.9 | alpha-catenin/vinculin |
| View | Download | 0.333 | N/A | N/A | a.87.1 | DBL homology domain (DH-domain) |
| View | Download | 0.313 | N/A | N/A | a.25.1 | Ferritin-like |
| View | Download | 0.299 | N/A | N/A | a.7.2 | Enzyme IIa from lactose specific PTS, IIa-lac |
| View | Download | 0.296 | N/A | N/A | f.13.1 | Family A G protein-coupled receptor-like |
| View | Download | 0.283 | N/A | N/A | a.29.3 | Acyl-CoA dehydrogenase C-terminal domain-like |
| View | Download | 0.283 | N/A | N/A | a.39.1 | EF-hand |
| View | Download | 0.279 | N/A | N/A | c.45.1 | (Phosphotyrosine protein) phosphatases II |
| View | Download | 0.241 | N/A | N/A | a.63.1 | Apolipophorin-III |
| View | Download | 0.230 | N/A | N/A | a.24.10 | Histidine-containing phosphotransfer domain, HPT domain |
| View | Download | 0.229 | N/A | N/A | f.19.1 | Aquaporin-like |
| View | Download | 0.227 | N/A | N/A | a.118.7 | 14-3-3 protein |
| View | Download | 0.219 | N/A | N/A | a.24.16 | Nucleotidyltransferase substrate binding subunit/domain |
| View | Download | 0.215 | N/A | N/A | f.14.1 | Voltage-gated potassium channels |
| Term | Confidence | Notes |
| Rho GTPase activator activity | 4.58620967349979 | bayes_pls_golite062009 |
| Rac GTPase activator activity | 4.48279904625182 | bayes_pls_golite062009 |
| binding | 2.79128751898373 | bayes_pls_golite062009 |
| GTPase regulator activity | 2.70614727793157 | bayes_pls_golite062009 |
| nucleoside-triphosphatase regulator activity | 2.68579854252375 | bayes_pls_golite062009 |
| guanyl-nucleotide exchange factor activity | 2.06038764955701 | bayes_pls_golite062009 |
| enzyme regulator activity | 1.9750017471254 | bayes_pls_golite062009 |
| small GTPase regulator activity | 1.95738547986197 | bayes_pls_golite062009 |
| protein binding | 1.29100556128076 | bayes_pls_golite062009 |
| general RNA polymerase II transcription factor activity | 1.27693544428588 | bayes_pls_golite062009 |
| signal transducer activity | 1.25507073225414 | bayes_pls_golite062009 |
| molecular transducer activity | 1.25507073225414 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 1.2233434243135 | bayes_pls_golite062009 |
| myosin heavy chain kinase activity | 1.15190288326422 | bayes_pls_golite062009 |
| Ras GTPase activator activity | 1.09070479183477 | bayes_pls_golite062009 |
| transcription regulator activity | 1.08577758274384 | bayes_pls_golite062009 |
| actin binding | 1.02058870188398 | bayes_pls_golite062009 |
| Rho guanyl-nucleotide exchange factor activity | 0.967362611034944 | bayes_pls_golite062009 |
| Ras guanyl-nucleotide exchange factor activity | 0.958295643211986 | bayes_pls_golite062009 |
| GTPase activator activity | 0.717730683557543 | bayes_pls_golite062009 |
| nucleic acid binding | 0.480348726111787 | bayes_pls_golite062009 |
| receptor activity | 0.434186339265983 | bayes_pls_golite062009 |
| DNA binding | 0.418154636457321 | bayes_pls_golite062009 |
| enzyme activator activity | 0.298334474872045 | bayes_pls_golite062009 |
| microfilament motor activity | 0.0044514849726196 | bayes_pls_golite062009 |
|
Region A: Residues: [654-821] |
1 11 21 31 41 51
| | | | | |
1 GVYYSELSTM ELSMIRAISL SLLAGKQLIS KTDPNYTSLV SMVFSNEKQV TGSFWNRMKI 60
61 MMSMEPKKPI TKTVFGAPLD VLCEKWGVDS DLGVGPVKIR IPIIIDELIS SLRQMDMSVE 120
121 GIFRKNGNIR RLRELTANID SNPTEAPDFS KENAIQLSAL LKKFIREL
|
| Detection Method: | |
| Confidence: | 207.927757 |
| Match: | 1am4A_ |
| Description: | p50 RhoGAP domain |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [822-963] |
1 11 21 31 41 51
| | | | | |
1 PQPILSTDLY ELWIKAAKID LEDEKQRVIL LIYSLLPTYN RNLLEALLSF LHWTSSFSYI 60
61 ENEMGSKMDI HNLSTVITPN ILYLRHKEIS NDNVPDEPES GLVDSFAQNK GENYFLAIEI 120
121 VDYLITHNEE MAMVPKFLMN LL
|
| Detection Method: | |
| Confidence: | 207.927757 |
| Match: | 1am4A_ |
| Description: | p50 RhoGAP domain |
| Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [964-1017] |
1 11 21 31 41 51
| | | | | |
1 KDVQLQKLDN YESINHFIST VMQSKTIDYS ECDIKTPVTV KDSTTTVIQG EINK
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
SCOP Match |
SCOP Description | ||
| View | Download | 0.302 | a.4.1 | Homeodomain-like |
| View | Download | 0.330 | a.5.2 | UBA-like |
| View | Download | 0.342 | d.11.1 | Penicillin-binding protein 2x (pbp-2x), c-terminal domain |
| View | Download | 0.486 | d.46.1 | Transcription-state regulator AbrB, the N-terminal DNA recognition domain |
| View | Download | 0.314 | d.186.1 | Head-to-tail joining protein W, gpW |
| View | Download | 0.239 | b.85.1 | Type III antifreeze protein, AFP III |
| View | Download | 0.227 | d.58.17 | Metal-binding domain |
| View | Download | 0.221 | g.18.1 | Complement control module/SCR domain |
| View | Download | 0.220 | a.44.1 | Disulphide-bond formation facilitator (DSBA), insertion domain |
| View | Download | 0.215 | a.50.1 | Anaphylotoxins (complement system) |
| View | Download | 0.200 | a.35.1 | lambda repressor-like DNA-binding domains |
