






| Protein: | MCD1 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 566 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MCD1.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..566] | [1..566] |
|
|
0.0 | [14..557] | [17..625] |
|
|
1.0E-92 | [14..375] | [7..347] |
|
|
1.0E-90 | [14..375] | [7..347] |
|
Region A: Residues: [1-210] |
1 11 21 31 41 51
| | | | | |
1 MVTENPQRLT VLRLATNKGP LAQIWLASNM SNIPRGSVIQ THIAESAKEI AKASGCDDES 60
61 GDNEYITLRT SGELLQGIVR VYSKQATFLL TDIKDTLTKI SMLFKTSQKM TSTVNRLNTV 120
121 TRVHQLMLED AVTEREVLVT PGLEFLDDTT IPVGLMAQEN SMERKVQGAA PWDTSLEVGR 180
181 RFSPDEDFEH NNLSSMNLDF DIEEGPITSK
|
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [211-566] |
1 11 21 31 41 51
| | | | | |
1 SWEEGTRQSS RNFDTHENYI QDDDFPLDDA GTIGWDLGIT EKNDQNNDDD DNSVEQGRRL 60
61 GESIMSEEPT DFGFDLDIEK EAPAGNIDTI TDAMTESQPK QTGTRRNSKL LNTKSIQIDE 120
121 ETENSESIAS SNTYKEERSN NLLTPQPTNF TTKRLWSEIT ESMSYLPDPI LKNFLSYESL 180
181 KKRKIHNGRE GSIEEPELNV SLNLTDDVIS NAGTNDNSFN ELTDNMSDFV PIDAGLNEAP 240
241 FPEENIIDAK TRNEQTTIQT EKVRPTPGEV ASKAIVQMAK ILRKELSEEK EVIFTDVLKS 300
301 QANTEPENIT KREASRGFFD ILSLATEGCI GLSQTEAFGN IKIDAKPALF ERFINA
|
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [219-380] |
1 11 21 31 41 51
| | | | | |
1 SSRNFDTHEN YIQDDDFPLD DAGTIGWDLG ITEKNDQNND DDDNSVEQGR RLGESIMSEE 60
61 PTDFGFDLDI EKEAPAGNID TITDAMTESQ PKQTGTRRNS KLLNTKSIQI DEETENSESI 120
121 ASSNTYKEER SNNLLTPQPT NFTTKRLWSE ITESMSYLPD PI
|
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [381-566] |
1 11 21 31 41 51
| | | | | |
1 LKNFLSYESL KKRKIHNGRE GSIEEPELNV SLNLTDDVIS NAGTNDNSFN ELTDNMSDFV 60
61 PIDAGLNEAP FPEENIIDAK TRNEQTTIQT EKVRPTPGEV ASKAIVQMAK ILRKELSEEK 120
121 EVIFTDVLKS QANTEPENIT KREASRGFFD ILSLATEGCI GLSQTEAFGN IKIDAKPALF 180
181 ERFINA
|
| Detection Method: | |
| Confidence: | 46.045757 |
| Match: | 1w1wE |
| Description: | Sc Smc1hd:Scc1-C complex, ATPgS |
Matching Structure (courtesy of the PDB):![]() |
|
| Term | Confidence | Notes |
| DNA binding | 3.84008666671174 | bayes_pls_golite062009 |
| binding | 3.38086362981788 | bayes_pls_golite062009 |
| transcription regulator activity | 2.53725013788849 | bayes_pls_golite062009 |
| nucleic acid binding | 2.4191162518892 | bayes_pls_golite062009 |
| sequence-specific DNA binding | 2.23378431307469 | bayes_pls_golite062009 |
| transcription factor activity | 1.63317649552979 | bayes_pls_golite062009 |
| structure-specific DNA binding | 1.38449475025903 | bayes_pls_golite062009 |
| protein binding | 0.961087148890615 | bayes_pls_golite062009 |
| transcription activator activity | 0.774002575315721 | bayes_pls_golite062009 |
| transcription factor binding | 0.68991166927379 | bayes_pls_golite062009 |
| DNA-dependent ATPase activity | 0.683954534315832 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity | 0.52992575338445 | bayes_pls_golite062009 |
| double-stranded DNA binding | 0.349632742873003 | bayes_pls_golite062009 |
| transcription repressor activity | 0.140777233468428 | bayes_pls_golite062009 |