| Protein: | TKL2 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 681 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TKL2.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..681] | [1..680] |
|
|
0.0 | [1..681] | [1..682] |
|
|
0.0 | [1..681] | [1..679] |
|
|
0.0 | [7..681] | [4..677] |
|
|
0.0 | [2..681] | [4..685] |
|
|
0.0 | [7..664] | [83..743] |
|
|
0.0 | [7..664] | [80..740] |
|
Region A: Residues: [1-128] |
1 11 21 31 41 51
| | | | | |
1 MAQFSDIDKL AVSTLRLLSV DQVESAQSGH PGAPLGLAPV AHVIFKQLRC NPNNEHWINR 60
61 DRFVLSNGHS CALLYSMLHL LGYDYSIEDL RQFRQVNSRT PGHPEFHSAG VEITSGPLGQ 120
121 GISNAVGM
|
|
Region B: Residues: [148-310] |
1 11 21 31 41 51
| | | | | |
1 DSYTFAIVGD GCLQEGVSSE TSSLAGHLQL GNLITFYDSN SISIDGKTSY SFDEDVLKRY 60
61 EAYGWEVMEV DKGDDDMESI SSALEKAKLS KDKPTIIKVT TTIGFGSLQQ GTAGVHGSAL 120
121 KADDVKQLKK RWGFDPNKSF VVPQEVYDYY KKTVVEPGQK LNE
|
| Detection Method: |  |
| Confidence: | 11000.0 |
| Match: | 1gpuA_ |
| Description: | Transketolase (TK), Pyr module; Transketolase (TK), PP module; Transketolase (TK), C-domain |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| transketolase activity | 7.85070252105246 | bayes_pls_golite062009 |
| transferase activity, transferring aldehyde or ketonic groups | 4.74831149446647 | bayes_pls_golite062009 |
| oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor | 2.93250853993668 | bayes_pls_golite062009 |
| pyruvate dehydrogenase activity | 2.81702263447118 | bayes_pls_golite062009 |
| pyruvate dehydrogenase (acetyl-transferring) activity | 2.6977837113283 | bayes_pls_golite062009 |
| catalytic activity | 2.25537597692103 | bayes_pls_golite062009 |
| binding | 0.980920092099572 | bayes_pls_golite062009 |
| transferase activity | 0.413024577830522 | bayes_pls_golite062009 |
| acetolactate synthase activity | 0.159086519260601 | bayes_pls_golite062009 |
|
Region A: Residues: [129-147] |
1 11 21 31 41 51
| | | | | |
1 AIAQANFAAT YNEDGFPIS
|
|
Region B: Residues: [311-340] |
1 11 21 31 41 51
| | | | | |
1 EWDRMFEEYK TKFPEKGKEL QRRLNGELPE
|
| Detection Method: | |
| Confidence: | 11000.0 |
| Match: | 1gpuA_ |
| Description: | Transketolase (TK), Pyr module; Transketolase (TK), PP module; Transketolase (TK), C-domain |
| Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [341-366] |
1 11 21 31 41 51
| | | | | |
1 GWEKHLPKFT PDDDALATRK TSQQVL
|
|
Region B: Residues: [465-681] |
1 11 21 31 41 51
| | | | | |
1 WVATHDSIGL GEDGPTHQPI ETLAHLRAIP NMHVWRPADG NETSAAYYSA IKSGRTPSVV 60
61 ALSRQNLPQL EHSSFEKALK GGYVIHDVEN PDIILVSTGS EVSISIDAAK KLYDTKKIKA 120
121 RVVSLPDFYT FDRQSEEYRF SVLPDGVPIM SFEVLATSSW GKYAHQSFGL DEFGRSGKGP 180
181 EIYKLFDFTA DGVASRAEKT INYYKGKQLL SPMGRAF
|
| Detection Method: | |
| Confidence: | 11000.0 |
| Match: | 1gpuA_ |
| Description: | Transketolase (TK), Pyr module; Transketolase (TK), PP module; Transketolase (TK), C-domain |
| Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [367-464] |
1 11 21 31 41 51
| | | | | |
1 TNMVQVLPEL IGGSADLTPS NLTRWEGAVD FQPPITQLGN YAGRYIRYGV REHGMGAIMN 60
61 GISAFGANYK PYGGTFLNFV SYAAGAVRLA ALSGNPVI
|
| Detection Method: | |
| Confidence: | 11000.0 |
| Match: | 1gpuA_ |
| Description: | Transketolase (TK), Pyr module; Transketolase (TK), PP module; Transketolase (TK), C-domain |
| Matching Structure (courtesy of the PDB): |
|
