| Protein: | TEL1 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 2787 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TEL1.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..1284] | [1..1284] |
|
|
0.0 | [1716..2786] | [493..1578] |
|
|
0.0 | [1719..2786] | [622..1707] |
|
|
0.0 | [1726..2786] | [1983..3065] |
|
|
0.0 | [1719..2786] | [1970..3055] |
|
|
0.0 | [1719..2786] | [1970..3055] |
|
Region A: Residues: [1-1325] |
1 11 21 31 41 51
| | | | | |
1 MEDHGIVETL NFLSSTKIKE RNNALDELTT ILKEDPERIP TKALSTTAEA LVELLASEHT 60
61 KYCDLLRNLT VSTTNKLSLS ENRLSTISYV LRLFVEKSCE RFKVKTLKLL LAVVPELMVK 120
121 DGSKSLLDAV SVHLSFALDA LIKSDPFKLK FMIHQWISLV DKICEYFQSQ MKLSMVDKTL 180
181 TNFISILLNL LALDTVGIFQ VTRTITWTVI DFLRLSKKEN GNTRLIMSLI NQLILKCHCF 240
241 SVIDTLMLIK EAWSYNLTIG CTSNELVQDQ LSLFDVMSSE LMNHKLPYMI GQENYVEELR 300
301 SESLVSLYRE YILLRLSNYK PQLFTVNHVE FSYIRGSRDK NSWFALPDFR LRDRGGRSVW 360
361 LKILGITKSL LTYFALNRKN ENYSLLFKRR KCDSDIPSIL RISDDMDTFL IHLLEENSSH 420
421 EFEVLGLQLC SFYGTLQDFT KSFAEQLKEL LFSKFEKIQC FNWVCFSFIP LLSQKECELS 480
481 NGDMARLFKV CLPLVKSNES CQLSCLLLAN SIKFSKQLLS DEKTINQIYD LYELSDILGP 540
541 ILVTNESFML WGYLQYVGKD FQSMNGISSA DRIFEWLKSK WNQLRGTDAK QDQFCNFISW 600
601 LGNKYDPENP FNDKKGEGAN PVSLCWDESH KIWQHFQEQR EFLLGVKPEE KSECFNTPFF 660
661 NLPKVSLDLT RYNEILYRLL ENIESDAFSS PLQKFTWVAK LIQIVDNLCG DSTFSEFIAA 720
721 YKRTTLITIP QLSFDSQNSY QSFFEEVLSI RTINVDHLVL DKINMKEIVN DFIRMQKNKS 780
781 QTGTSAINYF EASSEDTTQN NSPYTIGGRF QKPLHSTIDK AVRAYLWSSR NKSISERLVA 840
841 ILEFSDCVST DVFISYLGTV CQWLKQAIGE KSSYNKILEE FTEVLGEKLL CNHYSSSNQA 900
901 MLLLTSYIEA IRPQWLSYPE QPLNSDCNDI LDWIISRFED NSFTGVAPTV NLSMLLLSLL 960
961 QNHDLSHGSI RGGKQRVFAT FIKCLQKLDS SNIINIMNSI SSYMAQVSYK NQSIIFYEIK1020
1021 SLFGPPQQSI EKSAFYSLAM SMLSLVSYPS LVFSLEDMMT YSGFNHTRAF IQQALNKITV1080
1081 AFRYQNLTEL FEYCKFDLIM YWFNRTKVPT SKLEKEWDIS LFGFADIHEF LGRYFVEISA1140
1141 IYFSQGFNQK WILDMLHAIT GNGDAYLVDN SYYLCIPLAF ISGGVNELIF DILPQISGKT1200
1201 TVKYHKKYRL LMLKWIIRFT DLGSLTELRS TVEKLFPTSY LSPYLFENSS VSMRYQYPLH1260
1261 IPLALGATLV QTQFAHEKNN THEFKLLFLS VITDLEKTST YIGKLRCARE LKYLFVLYEN1320
1321 VLVKS
|
| Detection Method: |  |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [1326-1719] |
1 11 21 31 41 51
| | | | | |
1 STLNFIIIRL SKFLIDTQIH DEVITIFSSL LNLADKNTFE IEPSLPNLFC KIFIYLRENK 60
61 QLSPSFQQAI KLLEHRDLIK IKTWKYFLDA IFGNIVQDDI YENTELLDAS DCGVDDVVLV 120
121 SLLFSYARRP VASKIGCSLS KAAAINILKH HVPKEYLSKN FKLWFAALSR RILQQEVQRE 180
181 RSTNFNNEVH LKNFEMVFRH PEQPHMIYQR ISTFNKEAEL YDSTEVFFIS ECILTYLVGY 240
241 SIGNSESEFC FRDNIMNENK DKVAPLDKDV LNAIYPLANN FGMESFICDT YLSVNEPYNC 300
301 WLSKFARSLI HQISFNIPPI VCLYPLCKGS TAFCELVLTD LFFLSTTYDP KSCLNWSNRI 360
361 FTQIAMLLHV KDSEIKLKML FNVIKMIRMG SRCK
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [1720-2102] |
1 11 21 31 41 51
| | | | | |
1 ERNCLRIYSS LDLQEICQIS LKIKEFKFGY LLFEEMNMPN IREMNINTLQ KIYECINDGD 60
61 FLAGLPVPHS IEGVLNSINR IDSDTWKRFL FNNADFDANY TTSLEEEKES LIKATEDSGF 120
121 YGLTSLLESR LSGSSDVYKW NLELGDWKLL TPKVVDSKAK GLYYAIKNLP QDVGFAEKSL 180
181 EKSLLTIFDS RQHFISQTEW MDTLNAIIEF IKIAAIPQDV TSFPQTLMSI MKADKERLNT 240
241 IDFYDHKTTL KSRHTLMNVL SRNSLDENVK CSKYLRLGSI IQLANYVQLA IANGAPQDAL 300
301 RNATLMSKTV KNIAKLYDDP SVVSQIEKLA SFTSANALWE SREYKAPVMI MRDLLAQNEK 360
361 NISESILYDD FKLLINVPMD QIK
|
| Detection Method: | |
| Confidence: | 12.537602 |
| Match: | PF02259 |
| Description: | FAT domain |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [2103-2754] |
1 11 21 31 41 51
| | | | | |
1 ARLVKWSSES RLEPAAAIYE KIIVNWDINV EDHESCSDVF YTLGSFLDEQ AQKLRSNGEI 60
61 EDREHRSYTG KSTLKALELI YKNTKLPENE RKDAKRHYNR VLLQYNRDSE VLKALLLQKE 120
121 KFLWHALHFY LNTLVFSNRY DNDIIDKFCG LWFENDDNSK INQLLYKEIG TIPSWKFLPW 180
181 VNQIASKISM EENEFQKPLQ LTMKRLLYKL PYDSLYSVMS ILLYEKQSNK DTNISQKIQA 240
241 VKKILLELQG YDRGAFAKKY LLPVQEFCEM SVELANLKFV QNTKTLRLAN LKIGQYWLKQ 300
301 LNMEKLPLPT SNFTVKSSAD GRKARPYIVS VNETVGITTT GLSLPKIVTF NISDGTTQKA 360
361 LMKGSNDDLR QDAIMEQVFQ QVNKVLQNDK VLRNLDLGIR TYKVVPLGPK AGIIEFVANS 420
421 TSLHQILSKL HTNDKITFDQ ARKGMKAVQT KSNEERLKAY LKITNEIKPQ LRNFFFDSFP 480
481 DPLDWFEAKK TYTKGVAASS IVGYILGLGD RHLNNILLDC STGEPIHIDL GIAFDQGKLL 540
541 PIPELVPFRL TRDIVDGFGV TGVDGLFRRS CERVYAVLRK DYVKVMCVLN ILKWDPLYSW 600
601 VMSPVKKYEH LFEEEHEITN FDNVSKFISN NDRNENQESY RALKGVEEKL MG
|
| Detection Method: | |
| Confidence: | 167.980454 |
| Match: | 1e7uA_ |
| Description: | Phoshoinositide 3-kinase (PI3K) helical domain; Phoshoinositide 3-kinase (PI3K); Phoshoinositide 3-kinase (PI3K), catalytic domain |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| protein kinase activity | 5.4586557943719 | bayes_pls_golite062009 |
| phosphotransferase activity, alcohol group as acceptor | 5.04467222534257 | bayes_pls_golite062009 |
| kinase activity | 4.85903980916957 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 4.63692708178478 | bayes_pls_golite062009 |
| protein serine/threonine kinase activity | 4.46381887831481 | bayes_pls_golite062009 |
| transferase activity | 3.26787750561728 | bayes_pls_golite062009 |
| binding | 2.74863538127007 | bayes_pls_golite062009 |
| protein binding | 2.276111749106 | bayes_pls_golite062009 |
| ATP binding | 1.97600611746091 | bayes_pls_golite062009 |
| adenyl ribonucleotide binding | 1.93596671856664 | bayes_pls_golite062009 |
| adenyl nucleotide binding | 1.90928021591891 | bayes_pls_golite062009 |
| purine ribonucleotide binding | 1.65732943334212 | bayes_pls_golite062009 |
| ribonucleotide binding | 1.65726906484847 | bayes_pls_golite062009 |
| purine nucleotide binding | 1.63763394711025 | bayes_pls_golite062009 |
| nucleotide binding | 1.63195828048121 | bayes_pls_golite062009 |
| protein tyrosine kinase activity | 1.3898059094397 | bayes_pls_golite062009 |
| receptor signaling protein serine/threonine kinase activity | 1.38496328649031 | bayes_pls_golite062009 |
| receptor signaling protein activity | 1.27291233344322 | bayes_pls_golite062009 |
| catalytic activity | 1.21655087018101 | bayes_pls_golite062009 |
| calcium-dependent phospholipid binding | 1.06635493706319 | bayes_pls_golite062009 |
| transmembrane receptor protein kinase activity | 0.684204466593894 | bayes_pls_golite062009 |
| cyclin-dependent protein kinase activity | 0.499492353295369 | bayes_pls_golite062009 |
| nucleic acid binding | 0.444972929276369 | bayes_pls_golite062009 |
| magnesium ion binding | 0.393328812780268 | bayes_pls_golite062009 |
| clathrin binding | 0.35775052108553 | bayes_pls_golite062009 |
| neurexin binding | 0.27749877320051 | bayes_pls_golite062009 |
| MAP kinase activity | 0.26024936404169 | bayes_pls_golite062009 |
| transcription regulator activity | 0.222474717779546 | bayes_pls_golite062009 |
| DNA binding | 0.198054762876122 | bayes_pls_golite062009 |
| transmembrane receptor protein tyrosine kinase activity | 0.196560862858137 | bayes_pls_golite062009 |
| SNARE binding | 0.102282725391911 | bayes_pls_golite062009 |
| nuclear localization sequence binding | 0.0935103343162811 | bayes_pls_golite062009 |
| transcription factor activity | 0.026050048647416 | bayes_pls_golite062009 |
|
Region A: Residues: [2755-2787] |
1 11 21 31 41 51
| | | | | |
1 NGLSVESSVQ DLIQQATDPS NLSVIYMGWS PFY
|
| Detection Method: | |
| Confidence: | 15.920819 |
| Match: | PF02260 |
| Description: | FATC domain |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
