| Protein: | slo-PN |
| Organism: | Drosophila melanogaster |
| Length: | 1200 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for slo-PN.
| Description | E-value | Query Range |
Subject Range |
|
|
1092.0 | [0..18] | [1200..1] |
|
Region A: Residues: [1-395] |
1 11 21 31 41 51
| | | | | |
1 MASGLIDTNF SSTLANGMSG CDQSTVESLA DDPTDSPFDA DDCLKVRKYW CFLLSSIFTF 60
61 LAGLLVVLLW RAFAFVCCRK EPDLGPNDPK QKEQKASRNK QEFEGTFMTE AKDWAGELIS 120
121 GQTTTGRILV VLVFILSIAS LIIYFVDASS EEVERCQKWS NNITQQIDLA FNIFFMVYFF 180
181 IRFIAASDKL WFMLEMYSFV DYFTIPPSFV SIYLDRTWIG LRFLRALRLM TVPDILQYLN 240
241 VLKTSSSIRL AQLVSIFISV WLTAAGIIHL LENSGDPLDF NNAHRLSYWT CVYFLIVTMS 300
301 TVGYGDVYCE TVLGRTFLVF FLLVGLAMFA SSIPEIIELV GSGNKYGGEL KREHGKRHIV 360
361 VCGHITYESV SHFLKDFLHE DREDVDVEVV FLHRK
|
| Detection Method: |  |
| Confidence: | 66.0 |
| Match: | 2a79B |
| Description: | Mammalian Shaker Kv1.2 potassium channel- beta subunit complex |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [396-694] |
1 11 21 31 41 51
| | | | | |
1 PPDLELEGLF KRHFTTVEFF QGTIMNPIDL QRVKVHEADA CLVLANKYCQ DPDAEDAANI 60
61 MRVISIKNYS DDIRVIIQLM QYHNKAYLLN IPSWDWKQGD DVICLAELKL GFIAQSCLAP 120
121 GFSTMMANLF AMRSFKTSPD MQSWTNDYLR GTGMEMYTET LSPTFIGIPF AQATELCFSK 180
181 LKLLLLAIEI KGAEEGADSK ISINPRGAKI QANTQGFFIA QSADEVKRAW FYCKACHEDI 240
241 KDETLIKKCK CKNLTVQPRS KFDDLDEHHP APTFTPPELP KRVHVRGSVS GDITRDRED
|
| Detection Method: | |
| Confidence: | 23.522879 |
| Match: | 1lnqA |
| Description: | Potassium channel-related protein MthK |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| potassium channel activity | 7.19795882959285 | bayes_pls_golite062009 |
| voltage-gated potassium channel activity | 7.02492819589858 | bayes_pls_golite062009 |
| metal ion transmembrane transporter activity | 6.90465650760629 | bayes_pls_golite062009 |
| voltage-gated cation channel activity | 6.33923365642046 | bayes_pls_golite062009 |
| voltage-gated ion channel activity | 6.21728899427189 | bayes_pls_golite062009 |
| voltage-gated channel activity | 6.20461120293277 | bayes_pls_golite062009 |
| cation channel activity | 5.56619080264703 | bayes_pls_golite062009 |
| ion channel activity | 5.01725373023133 | bayes_pls_golite062009 |
| passive transmembrane transporter activity | 4.95840588988444 | bayes_pls_golite062009 |
| channel activity | 4.95840588988444 | bayes_pls_golite062009 |
| substrate-specific channel activity | 4.90604391861681 | bayes_pls_golite062009 |
| gated channel activity | 4.76975011621094 | bayes_pls_golite062009 |
| monovalent inorganic cation transmembrane transporter activity | 2.96809690970616 | bayes_pls_golite062009 |
| cation transmembrane transporter activity | 2.73807350248822 | bayes_pls_golite062009 |
| ion transmembrane transporter activity | 2.67515190518646 | bayes_pls_golite062009 |
| substrate-specific transmembrane transporter activity | 2.33083670641501 | bayes_pls_golite062009 |
| inorganic cation transmembrane transporter activity | 2.13014428099026 | bayes_pls_golite062009 |
| retinol dehydrogenase activity | 2.01726075025767 | bayes_pls_golite062009 |
| hydrogen ion transmembrane transporter activity | 1.91774061209278 | bayes_pls_golite062009 |
| catalytic activity | 1.79741889688267 | bayes_pls_golite062009 |
| potassium ion transmembrane transporter activity | 1.57069429249737 | bayes_pls_golite062009 |
| steroid dehydrogenase activity | 1.19349599687216 | bayes_pls_golite062009 |
| steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | 1.15786007823324 | bayes_pls_golite062009 |
| sterol transporter activity | 1.14689358041007 | bayes_pls_golite062009 |
| molecular transducer activity | 1.10146351042336 | bayes_pls_golite062009 |
| signal transducer activity | 1.10146351042336 | bayes_pls_golite062009 |
| oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | 0.82673050487418 | bayes_pls_golite062009 |
| oxidoreductase activity, acting on CH-OH group of donors | 0.824879127880521 | bayes_pls_golite062009 |
| transporter activity | 0.793769336118517 | bayes_pls_golite062009 |
| nucleic acid binding | 0.707555098275754 | bayes_pls_golite062009 |
| receptor activity | 0.669414726094584 | bayes_pls_golite062009 |
| transmembrane transporter activity | 0.635891484075352 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 0.555188550031886 | bayes_pls_golite062009 |
| transmembrane receptor activity | 0.554841724526358 | bayes_pls_golite062009 |
| protein binding | 0.507836099271263 | bayes_pls_golite062009 |
| binding | 0.343109880193463 | bayes_pls_golite062009 |
| DNA binding | 0.325332812205271 | bayes_pls_golite062009 |
| copper ion binding | 0.2470667568593 | bayes_pls_golite062009 |
| active transmembrane transporter activity | 0.239024094835991 | bayes_pls_golite062009 |
|
Region A: Residues: [695-790] |
1 11 21 31 41 51
| | | | | |
1 TNLLNRNVRR PNGTGNGTGG MHHMNNTAAA AAAAAAAGKQ VNKVKPTVNV SRQVEGQVIS 60
61 PSQYNRPTSR SSGTGTQNQN GGVSLPAGIA DDQSKD
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [791-1200] |
1 11 21 31 41 51
| | | | | |
1 FDFEKTEMKY DSTGMFHWSP AKSLEDCILD RNQAAMTVLN GHVVVCLFAD PDSPLIGLRN 60
61 LVMPLRASNF HYHELKHVVI VGSVDYIRRE WKMLQNLPKI SVLNGSPLSR ADLRAVNVNL 120
121 CDMCCILSAK VPSNDDPTLA DKEAILASLN IKAMTFDDTI GVLSQRGPEF DNLSATAGSP 180
181 IVLQRRGSVY GANVPMITEL VNDSNVQFLD QDDDDDPDTE LYLTQPFACG TAFAVSVLDS 240
241 LMSTTYFNQN ALTLIRSLIT GGATPELELI LAEGAGLRGG YSTVESLSNR DRCRVGQISL 300
301 YDGPLAQFGE CGKYGDLFVA ALKSYGMLCI GLYRFRDTSS SCDASSKRYV ITNPPDDFSL 360
361 LPTDQVFVLM QFDPGLEYKP PAVRAPAGGR GTNTQGSGVG GGGSNKDDNS
|
| Detection Method: | |
| Confidence: | 2.8 |
| Match: | 1lnqA |
| Description: | Potassium channel-related protein MthK |
| Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| potassium channel activity | 7.202408784466 | bayes_pls_golite062009 |
| voltage-gated potassium channel activity | 7.02827897972893 | bayes_pls_golite062009 |
| metal ion transmembrane transporter activity | 6.87383718666495 | bayes_pls_golite062009 |
| voltage-gated cation channel activity | 6.34341135807817 | bayes_pls_golite062009 |
| voltage-gated ion channel activity | 6.22204288894013 | bayes_pls_golite062009 |
| voltage-gated channel activity | 6.2094216063314 | bayes_pls_golite062009 |
| cation channel activity | 5.57352831106363 | bayes_pls_golite062009 |
| ion channel activity | 5.02493108579252 | bayes_pls_golite062009 |
| passive transmembrane transporter activity | 4.96639582515843 | bayes_pls_golite062009 |
| channel activity | 4.96639582515843 | bayes_pls_golite062009 |
| substrate-specific channel activity | 4.91395304996323 | bayes_pls_golite062009 |
| gated channel activity | 4.77703666141432 | bayes_pls_golite062009 |
| monovalent inorganic cation transmembrane transporter activity | 2.89387517936987 | bayes_pls_golite062009 |
| cation transmembrane transporter activity | 2.72791814044378 | bayes_pls_golite062009 |
| ion transmembrane transporter activity | 2.67765801390314 | bayes_pls_golite062009 |
| substrate-specific transmembrane transporter activity | 2.35275220137267 | bayes_pls_golite062009 |
| inorganic cation transmembrane transporter activity | 2.09218991631308 | bayes_pls_golite062009 |
| hydrogen ion transmembrane transporter activity | 1.91294607339699 | bayes_pls_golite062009 |
| retinol dehydrogenase activity | 1.67790172484722 | bayes_pls_golite062009 |
| catalytic activity | 1.65938032155125 | bayes_pls_golite062009 |
| potassium ion transmembrane transporter activity | 1.30544811445848 | bayes_pls_golite062009 |
| molecular transducer activity | 1.13917599808599 | bayes_pls_golite062009 |
| signal transducer activity | 1.13917599808599 | bayes_pls_golite062009 |
| sterol transporter activity | 1.1340080668117 | bayes_pls_golite062009 |
| steroid dehydrogenase activity | 0.87204519429381 | bayes_pls_golite062009 |
| transporter activity | 0.852768781758211 | bayes_pls_golite062009 |
| steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | 0.840542793047449 | bayes_pls_golite062009 |
| nucleic acid binding | 0.742068313615785 | bayes_pls_golite062009 |
| receptor activity | 0.692499944712409 | bayes_pls_golite062009 |
| transmembrane transporter activity | 0.688412180298523 | bayes_pls_golite062009 |
| protein binding | 0.610214344005539 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 0.588406835418016 | bayes_pls_golite062009 |
| transmembrane receptor activity | 0.576415677502347 | bayes_pls_golite062009 |
| oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | 0.501691937400574 | bayes_pls_golite062009 |
| oxidoreductase activity, acting on CH-OH group of donors | 0.501572482308387 | bayes_pls_golite062009 |
| binding | 0.445541100906877 | bayes_pls_golite062009 |
| DNA binding | 0.335306484866611 | bayes_pls_golite062009 |
| copper ion binding | 0.253235147806174 | bayes_pls_golite062009 |
| active transmembrane transporter activity | 0.248538814281934 | bayes_pls_golite062009 |
