YRC Public Data Repository - Protein Structure Prediction

Protein:	CWC24_SCHPO
Organism:	Schizosaccharomyces pombe 972h-
Length:	533 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CWC24_SCHPO.

Description	E-value	Query Range	Subject Range
gi\|61370453, gi\|... - gi\|61370453\|gb\|AAX43498.1\| zinc finger protein 183 [synthetic construct], gi\|61370447\|gb\|AAX43497.1\|...	216.0	[0..10]	[311..4]
gi\|109132082 - gi\|109132082\|ref\|XP_001083433.1\| PREDICTED: ring finger protein 113A [Macaca mulatta]	216.0	[0..10]	[311..4]
gi\|61360729, gi\|... - gi\|61360729\|gb\|AAX41914.1\| zinc finger protein 183 [synthetic construct], gi\|208968725\|dbj\|BAG74201.... RNF113A - ring finger protein 113A	216.0	[0..10]	[311..4]
gi\|55664148 - gi\|55664148\|ref\|XP_529135.1\| PREDICTED: ring finger protein 113A [Pan troglodytes]	216.0	[0..10]	[311..4]
gi\|19354278, gi\|... - gi\|23943840\|ref\|NP_705723.1\| ring finger protein 113A1 [Mus musculus], gi\|19354278\|gb\|AAH24906.1\| Ri...	215.0	[0..10]	[305..4]
gi\|40891590 - gi\|40891590\|gb\|AAR97521.1\| zinc finger protein 183 [Rattus norvegicus]	214.0	[0..10]	[305..4]

Back

Predicted Domain #1

Region A:
Residues: [1-138]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEQKNLNINQ ASGSKINTEL AVPIFQSRRR HRPRQGLKRK KGFKRDDDSG GSSESSNEDM  60
   61 RDNIPIVSGR KKTVRLNRLQ RESEQFENSA LKDINVEYQS NLSATGESVN TTTVSAINED 120
  121 TREVILGRPS PKLANQST

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [139-229]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LPTELFQSQN DYSRFLPKRK DFEKKSQVGP VLSSNASTVR MNTIIDYQPD VCKDYKLTGY  60
   61 CGYGDTCKFL HMREDYKAGW QLDREWDSVQ E

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	1.49
Match:	2cqeA
Description:	Solution Structure of the Zinc-finger domain in KIAA1064 protein
Matching Structure (courtesy of the PDB):

Predicted Domain #3

Region A:
Residues: [230-363]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KYKKGAKLEE GMVKNEKKED IPFVCLICKK DYRSPIATTC GHHFCEQCAI TRYRKTPTCI  60
   61 QCGADTKGLF SVDKNFDRLL KNRKSKNDEA VKQKVGGFES NNSATTEVSE RKDREASFQG 120
  121 FADTLAKPNT SAQQ

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	13.09691
Match:	1rmdA
Description:	RAG1 DIMERIZATION DOMAIN
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
ubiquitin-protein ligase activity	5.78506998502716	bayes_pls_golite062009
small conjugating protein ligase activity	5.55686022186257	bayes_pls_golite062009
	4.77196423114965	bayes_pls_golite062009
acid-amino acid ligase activity	4.59153177011595	bayes_pls_golite062009
ligase activity, forming carbon-nitrogen bonds	3.07217714843839	bayes_pls_golite062009
RNA binding	3.04658201081989	bayes_pls_golite062009
snRNA binding	2.60432246247067	bayes_pls_golite062009
U1 snRNA binding	2.4012085357866	bayes_pls_golite062009
ligase activity	2.30828657077565	bayes_pls_golite062009
binding	2.19426901055464	bayes_pls_golite062009
protein binding	1.73461977726143	bayes_pls_golite062009
transcription regulator activity	1.62076236255768	bayes_pls_golite062009
mRNA binding	1.30742677372942	bayes_pls_golite062009
nucleic acid binding	1.22180889694654	bayes_pls_golite062009
small conjugating protein-specific protease activity	1.2126425713931	bayes_pls_golite062009
ubiquitin-specific protease activity	1.03469202541773	bayes_pls_golite062009
DNA binding	1.00346149950987	bayes_pls_golite062009
chromatin binding	0.89589330553881	bayes_pls_golite062009
cysteine-type peptidase activity	0.50197530717959	bayes_pls_golite062009
specific RNA polymerase II transcription factor activity	0.47352407708364	bayes_pls_golite062009
transcription factor binding	0.39685947299825	bayes_pls_golite062009
transcription factor activity	0.382098789505496	bayes_pls_golite062009
ubiquitin thiolesterase activity	0.265769062717221	bayes_pls_golite062009
structure-specific DNA binding	0.240825841910931	bayes_pls_golite062009
catalytic activity	0.14112008370434	bayes_pls_golite062009
double-stranded DNA binding	0.0129353639725593	bayes_pls_golite062009

Predicted Domain #4

Region A:
Residues: [364-425]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KMPSLGDNSN TIISKYFIRE ITESNIVHFK RLVRVVLEAS YSDKFYRLVL KNPDYARIAT  60
   61 FE

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #5

Region A:
Residues: [426-533]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DKFVGAISSL VAEDNSLYVT VLCVLAPYRC LGIGSLLIDH VKKTAINNNI DRISLHVQTT  60
   61 NESVIKWYTA HGFKIVKQIN DFYRRLENKS AFYMVCPLSA HNNIISNH

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	15.221849
Match:	2ob0A
Description:	No description for 2ob0A was found.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: