| Protein: | Eph-PB |
| Organism: | Drosophila melanogaster |
| Length: | 1047 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Eph-PB.
| Description | E-value | Query Range |
Subject Range |
|
|
1006.0 | [0..14] | [1047..20] |
|
Region A: Residues: [1-217] |
1 11 21 31 41 51
| | | | | |
1 MTKSALKSAF YKNQAPISEQ NRSQIVSRMS LLRTILLIII SIHFKLAHAD QVVLLDTTRE 60
61 ATLEWTRYPY GPQAQTPGWV EESFTDFVKG INWRSYVVCD VAYHNVNNWL WSPFIDRGSA 120
121 NRLYIEIQFT IRDCSLFPGN ALSCKETFSL LFYEFDAATR EPPPWQTDSY RLIARIAAGE 180
181 GRFNQNSDVD INTEVKSIAV NKKGVYFAFR DQGACIS
|
| Detection Method: |  |
| Confidence: | 82.69897 |
| Match: | 1nukA |
| Description: | Ligand-binding domain of the ephb2 receptor tyrosine kinase |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| integrin binding | 3.61193098087012 | bayes_pls_golite062009 |
| transmembrane receptor activity | 2.80879825615822 | bayes_pls_golite062009 |
| receptor activity | 2.77268648576901 | bayes_pls_golite062009 |
| transmembrane receptor protein tyrosine kinase activity | 2.47762337031838 | bayes_pls_golite062009 |
| binding | 2.31774167130542 | bayes_pls_golite062009 |
| transmembrane receptor protein kinase activity | 2.23073603832866 | bayes_pls_golite062009 |
| phosphatidylserine binding | 2.22270974208755 | bayes_pls_golite062009 |
| molecular transducer activity | 2.03595043486636 | bayes_pls_golite062009 |
| signal transducer activity | 2.03595043486636 | bayes_pls_golite062009 |
| protein binding | 1.90867517664953 | bayes_pls_golite062009 |
| fucose binding | 1.72607684089801 | bayes_pls_golite062009 |
| protein kinase activity | 1.70755634087208 | bayes_pls_golite062009 |
| monosaccharide binding | 1.62596107035359 | bayes_pls_golite062009 |
| phosphotransferase activity, alcohol group as acceptor | 1.39122779055629 | bayes_pls_golite062009 |
| kinase activity | 1.31546222648513 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 1.28997154411534 | bayes_pls_golite062009 |
| carbohydrate binding | 1.26743933952271 | bayes_pls_golite062009 |
| vascular endothelial growth factor receptor activity | 1.21634643105777 | bayes_pls_golite062009 |
| protein tyrosine kinase activity | 1.18833031215069 | bayes_pls_golite062009 |
| sugar binding | 1.1562287794497 | bayes_pls_golite062009 |
| glycoprotein binding | 0.68697655195721 | bayes_pls_golite062009 |
| protein complex binding | 0.56054373949313 | bayes_pls_golite062009 |
| nucleic acid binding | 0.533285414042183 | bayes_pls_golite062009 |
| transferase activity | 0.530643564656921 | bayes_pls_golite062009 |
| receptor binding | 0.365344483970243 | bayes_pls_golite062009 |
| DNA binding | 0.324772578014229 | bayes_pls_golite062009 |
| small conjugating protein ligase activity | 0.24891369301653 | bayes_pls_golite062009 |
| ubiquitin-protein ligase activity | 0.16022291279782 | bayes_pls_golite062009 |
| phosphatidylethanolamine binding | 0.121022714964449 | bayes_pls_golite062009 |
|
Region A: Residues: [218-596] |
1 11 21 31 41 51
| | | | | |
1 VLAVKVYYIT CPAVTENFAH FNETPTGREI TIIEKQNGTC VDNAEPYETP TYLCKGDGKW 60
61 TILTGGCRCK AGYEPNYTNK TCTECPLGTF KSPEVTKCTP CPPNSNASKT GSPFCKCASG 120
121 FYRHPNDGRH MPCYSPPAAP TNLTLLFVDQ TSAIISWSAP AKNESFSSET NSKIYHSDIV 180
181 YKIKCNICSP NVVYNPSTDT FNETKITLTN LEPVTTYTVQ IHAINSVSHI NEFKRHSNES 240
241 SLVAVSDIVF SNTSLLNIPL DLNEVKTGQA EIVFTTESVL LSTVFNLRIL AITNKDADLE 300
301 WDKPVQSDFP LEFYEVRWFP KVELDAINKS ALNTKETKAH IVGLLENTEY GFQVRCKTNN 360
361 GFGSYSNMIY AQTLQSVGS
|
| Detection Method: | |
| Confidence: | 17.522879 |
| Match: | 1m6bA |
| Description: | Receptor protein-tyrosine kinase Erbb-3 extracellular domain; Receptor protein-tyrosine kinase Erbb-3 Cys-rich domains |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| receptor activity | 3.83269261081332 | bayes_pls_golite062009 |
| transmembrane receptor activity | 3.75945815830294 | bayes_pls_golite062009 |
| G-protein coupled receptor activity | 3.09281229196379 | bayes_pls_golite062009 |
| molecular transducer activity | 2.99319600166105 | bayes_pls_golite062009 |
| signal transducer activity | 2.99319600166105 | bayes_pls_golite062009 |
| insulin-like growth factor I binding | 2.97927266804248 | bayes_pls_golite062009 |
| glycosaminoglycan binding | 1.94753631697974 | bayes_pls_golite062009 |
| binding | 1.87302803330255 | bayes_pls_golite062009 |
| polysaccharide binding | 1.72554005663659 | bayes_pls_golite062009 |
| protein binding | 1.69661396118522 | bayes_pls_golite062009 |
| transmembrane receptor protein kinase activity | 1.50579173120225 | bayes_pls_golite062009 |
| protein kinase activity | 1.43632437878638 | bayes_pls_golite062009 |
| integrin binding | 1.40983775289543 | bayes_pls_golite062009 |
| insulin-like growth factor II binding | 1.39804733127147 | bayes_pls_golite062009 |
| transmembrane receptor protein tyrosine kinase activity | 1.36671598599873 | bayes_pls_golite062009 |
| phosphotransferase activity, alcohol group as acceptor | 1.16530645523007 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 1.12585418084562 | bayes_pls_golite062009 |
| kinase activity | 1.11577341189523 | bayes_pls_golite062009 |
| growth factor binding | 1.1095340886971 | bayes_pls_golite062009 |
| insulin-like growth factor receptor activity | 1.05533763659606 | bayes_pls_golite062009 |
| actin filament binding | 0.855558247588515 | bayes_pls_golite062009 |
| heparin binding | 0.596331166056362 | bayes_pls_golite062009 |
| transferase activity | 0.435331931559158 | bayes_pls_golite062009 |
| epidermal growth factor receptor binding | 0.430075899423884 | bayes_pls_golite062009 |
| protein-hormone receptor activity | 0.42902267001067 | bayes_pls_golite062009 |
| glycoprotein binding | 0.41080910982871 | bayes_pls_golite062009 |
| nucleic acid binding | 0.370391722473665 | bayes_pls_golite062009 |
| receptor binding | 0.319201203357304 | bayes_pls_golite062009 |
| phosphatase activator activity | 0.234175951765568 | bayes_pls_golite062009 |
| protein tyrosine kinase activity | 0.231213253402712 | bayes_pls_golite062009 |
| pattern binding | 0.195655028782749 | bayes_pls_golite062009 |
| enzyme activator activity | 0.126307392530805 | bayes_pls_golite062009 |
|
Region A: Residues: [597-669] |
1 11 21 31 41 51
| | | | | |
1 VYDDSVQIRF IAGAIVTGVL FLVIFIIATV YFMRSKHQDD LDKKSTNHLP LPLDYASNEV 60
61 TTPLFGNSRS YVD
|
| Detection Method: | |
| Confidence: | 5.09691 |
| Match: | 2v5yA |
| Description: | No description for 2v5yA was found. |
|
Region A: Residues: [670-966] |
1 11 21 31 41 51
| | | | | |
1 PHTYEDPNQA IREFAREIDA NYITIEAIIG GGEFGDVCRG RLKIPPNFVQ DIDVAIKTLK 60
61 PGSSEKARCD FLTEASIMGQ FDHPNVIYLQ GVVTRSNPVM IITEYMENGS LDTFLRVNDG 120
121 KFQTLQLIVM LRGIASGMSY LSDMNYVHRD LAARNVLVNA QLICKIADFG LSREIENASD 180
181 AYTTRGGKIP VRWTAPEAIA FRKFTSASDV WSYGVVLWEV MSYGERPYWN WSNQDVIKSI 240
241 EKGYRLPAPM DCPEALYQLM LDCWQKQRTH RPTFASIVST LDNLARQPQS LLTTRPS
|
| Detection Method: | |
| Confidence: | 73.045757 |
| Match: | 2helA |
| Description: | No description for 2helA was found. |
|
Region A: Residues: [967-1047] |
1 11 21 31 41 51
| | | | | |
1 PESDGNHILD GQRGQNIFIS TDLWLEHIKM SRYCHHFKEA NLINAQQISR LTAQQLSDMG 60
61 ITLVGHQKKI LHQARQLDTI I
|
| Detection Method: | |
| Confidence: | 80.69897 |
| Match: | 2qoqA |
| Description: | No description for 2qoqA was found. |
