YRC Public Data Repository - Protein Structure Prediction

Protein:	PRIB_ECOLI
Organism:	Escherichia coli
Length:	104 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PRIB_ECOLI.

Description	E-value	Query Range	Subject Range
SSB_CUPNH - Single-stranded DNA-binding protein OS=Cupriavidus necator (strain ATCC 17699 / H16 / DSM 428 / Stan... SSB_ALCEU - (P59927) Single-strand binding protein (SSB) (Helix-destabilizing protein) SSB_RALEU - (P59927) Single-stranded DNA-binding protein (SSB) (Helix-destabilizing protein)	154.0	[0..3]	[103..5]
SSB_SHEHA - Single-stranded DNA-binding protein OS=Shewanella hanedai GN=ssb PE=3 SV=1	150.0	[0..3]	[103..7]
gi\|124265304, gi... - gi\|124265304\|ref\|YP_001019308.1\| single-strand binding protein [Methylibium petroleiphilum PM1], gi\|... gi\|47574068 - gi\|47574068\|ref\|ZP_00244105.1\| COG0629: Single-stranded DNA-binding protein [Rubrivivax gelatinosus ...	150.0	[0..2]	[100..4]
gi\|56477626, gi\|... - gi\|56477626\|ref\|YP_159215.1\| single-strand binding protein (SSB) (helix-destabilizing protein) [Arom...	150.0	[0..2]	[103..4]
gi\|91794661, gi\|... - gi\|91794661\|ref\|YP_564312.1\| single-strand binding protein [Shewanella denitrificans OS217], gi\|9171...	149.0	[0..3]	[104..7]
gi\|221086942, gi... - gi\|221086942\|ref\|ZP_03556482.1\| single-strand binding protein [Geobacillus sp. Y412MC61], gi\|2207089... gi\|229497917, gi... - gi\|229497917\|ref\|ZP_04391616.1\| single-strand binding protein [Geobacillus sp. Y412MC52], gi\|2293313... gi\|56381858, gi\|... - gi\|56422016\|ref\|YP_149334.1\| single-strand DNA-binding protein [Geobacillus kaustophilus HTA426], gi...	149.0	[0..1]	[103..1]
SO4028 - single-strand binding protein SSB_SHEON - Single-stranded DNA-binding protein OS=Shewanella oneidensis (strain MR-1) GN=ssb PE=3 SV=1	147.0	[0..3]	[104..7]
SSB_NITEU - Single-stranded DNA-binding protein OS=Nitrosomonas europaea GN=ssb PE=3 SV=1 SSB_NITEU - Single-stranded DNA-binding protein OS=Nitrosomonas europaea (strain ATCC 19718 / NBRC 14298) GN=ssb...	147.0	[0..2]	[103..4]
gi\|127511469, gi... - gi\|78367116\|ref\|ZP_00837390.1\| Single-strand binding protein [Shewanella sp. PV-4], gi\|78360889\|gb\|E...	146.0	[0..3]	[103..7]
gi\|78188206, gi\|... - gi\|78188206\|ref\|YP_378544.1\| single-strand binding protein [Chlorobium chlorochromatii CaD3], gi\|781...	146.0	[0..2]	[102..17]

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Predicted Domain #1

Region A:
Residues: [1-104]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTNRLVLSGT VCRAPLRKVS PSGIPHCQFV LEHRSVQEEA GFHRQAWCQM PVIVSGHENQ  60
   61 AITHSITVGS RITVQGFISC HKAKNGLSKM VLHAEQIELI DSGD

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	23.0
Match:	1txyA
Description:	E. coli PriB
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
nucleic acid binding	4.02967008021862	bayes_pls_golite062009
DNA binding	3.62735703519187	bayes_pls_golite062009
binding	3.3974561625489	bayes_pls_golite062009
structure-specific DNA binding	3.06066809614422	bayes_pls_golite062009
single-stranded DNA binding	3.0183551365402	bayes_pls_golite062009
transcription regulator activity	2.20239961025491	bayes_pls_golite062009
structural constituent of ribosome	2.13063800565247	bayes_pls_golite062009
structural molecule activity	1.9177190829469	bayes_pls_golite062009
telomeric DNA binding	1.7847835613194	bayes_pls_golite062009
single-stranded telomeric DNA binding	1.48033977789232	bayes_pls_golite062009
telomerase inhibitor activity	1.25988289474883	bayes_pls_golite062009
ribonuclease activity	1.19236946227657	bayes_pls_golite062009
DNA helicase activity	1.12203697857261	bayes_pls_golite062009
transcription factor activity	1.05816813143865	bayes_pls_golite062009
sequence-specific DNA binding	0.86170694706755	bayes_pls_golite062009
DNA-dependent ATPase activity	0.638831894247026	bayes_pls_golite062009
nuclease activity	0.57381531077345	bayes_pls_golite062009
translation regulator activity	0.515576958825022	bayes_pls_golite062009
translation factor activity, nucleic acid binding	0.468402630523277	bayes_pls_golite062009
nucleotidyltransferase activity	0.325774164899685	bayes_pls_golite062009
RNA binding	0.31028563542112	bayes_pls_golite062009
exonuclease activity	0.28313884527829	bayes_pls_golite062009
translation initiation factor activity	0.2080607201312	bayes_pls_golite062009
exoribonuclease activity, producing 5'-phosphomonoesters	0.125256208482441	bayes_pls_golite062009
exoribonuclease activity	0.109774918833391	bayes_pls_golite062009
RNA polymerase activity	0.10868826895563	bayes_pls_golite062009
DNA-directed RNA polymerase activity	0.10868826895563	bayes_pls_golite062009
exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	0.0954216620147701	bayes_pls_golite062009
ATP-dependent DNA helicase activity	0.0179535526984695	bayes_pls_golite062009
helicase activity	0.0121541775159524	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: