| Protein: | gi|2358010 |
| Organism: | Cloning vector pGR8 |
| Length: | 1392 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|2358010.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [3..1222] | [1294..2478] |
|
|
0.0 | [1..1390] | [1..1397] |
|
|
0.0 | [1..1379] | [1..1379] |
|
|
0.0 | [4..1388] | [15..1416] |
|
|
0.0 | [4..1389] | [12..1409] |
|
|
0.0 | [3..1223] | [1237..2376] |
|
|
0.0 | [5..1379] | [3..1379] |
|
|
0.0 | [4..1388] | [15..1412] |
|
Region A: Residues: [1-131] |
1 11 21 31 41 51
| | | | | |
1 MTNEKVWIEK LDNPTLSVLP HDFLRPQQEP YTKQATYSLQ LPQLDVPHDS FSNKYAVALS 60
61 VWAALIYRVT GDDDIVLYIA NNKILRFNIQ PTWSFNELYS TINNELNKLN SIEANFSFDE 120
121 LAEKIQSCQD L
|
| Detection Method: |  |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
| MCM Score |
GO Score |
GO Term |
SCOP Match |
SCOP Description | ||
| View | Download | 0.681 | 0.526 | cytoplasm | c.47.1 | Thioredoxin-like |
| View | Download | 0.574 | 0.146 | cytoplasm | a.118.9 | ENTH/VHS domain |
| View | Download | 0.599 | 0.127 | cytoplasm | d.110.4 | SNARE-like |
| View | Download | 0.672 | N/A | N/A | d.134.1 | Sulfite reductase hemoprotein (SiRHP), domains 2 and 4 |
| View | Download | 0.547 | N/A | N/A | d.110.4 | SNARE-like |
| View | Download | 0.544 | N/A | N/A | b.55.1 | PH domain-like |
| View | Download | 0.514 | N/A | N/A | b.55.1 | PH domain-like |
| View | Download | 0.512 | N/A | N/A | d.134.1 | Sulfite reductase hemoprotein (SiRHP), domains 2 and 4 |
| View | Download | 0.498 | N/A | N/A | c.72.2 | MurD-like peptide ligases, catalytic domain |
| View | Download | 0.489 | N/A | N/A | d.110.1 | Profilin (actin-binding protein) |
| View | Download | 0.475 | N/A | N/A | d.110.4 | SNARE-like |
| View | Download | 0.471 | N/A | N/A | b.55.1 | PH domain-like |
| View | Download | 0.455 | N/A | N/A | d.155.1 | Pyruvoyl-dependent histidine and arginine decarboxylases |
| View | Download | 0.455 | N/A | N/A | d.110.1 | Profilin (actin-binding protein) |
| View | Download | 0.448 | N/A | N/A | b.55.1 | PH domain-like |
| View | Download | 0.433 | N/A | N/A | c.47.1 | Thioredoxin-like |
| View | Download | 0.423 | N/A | N/A | d.134.1 | Sulfite reductase hemoprotein (SiRHP), domains 2 and 4 |
| View | Download | 0.397 | N/A | N/A | c.47.1 | Thioredoxin-like |
| View | Download | 0.397 | N/A | N/A | c.51.1 | Anticodon-binding domain of Class II aaRS |
| View | Download | 0.394 | N/A | N/A | d.110.4 | SNARE-like |
| View | Download | 0.390 | N/A | N/A | d.110.4 | SNARE-like |
| View | Download | 0.386 | N/A | N/A | d.110.4 | SNARE-like |
| View | Download | 0.378 | N/A | N/A | d.110.1 | Profilin (actin-binding protein) |
| View | Download | 0.374 | N/A | N/A | c.116.1 | alpha/beta knot |
| View | Download | 0.371 | N/A | N/A | a.24.10 | Histidine-containing phosphotransfer domain, HPT domain |
| View | Download | 0.362 | N/A | N/A | c.121.1 | Ribose/Galactose isomerase RpiB/AlsB |
| View | Download | 0.359 | N/A | N/A | d.134.1 | Sulfite reductase hemoprotein (SiRHP), domains 2 and 4 |
| View | Download | 0.352 | N/A | N/A | d.110.4 | SNARE-like |
| View | Download | 0.352 | N/A | N/A | c.72.2 | MurD-like peptide ligases, catalytic domain |
| View | Download | 0.348 | N/A | N/A | d.204.1 | Ribosome binding protein Y (YfiA homologue) |
| View | Download | 0.346 | N/A | N/A | d.110.4 | SNARE-like |
| View | Download | 0.346 | N/A | N/A | d.110.1 | Profilin (actin-binding protein) |
| View | Download | 0.340 | N/A | N/A | d.110.1 | Profilin (actin-binding protein) |
| View | Download | 0.336 | N/A | N/A | d.93.1 | SH2 domain |
| View | Download | 0.327 | N/A | N/A | c.47.2 | RNA 3'-terminal phosphate cyclase, RPTC, insert domain |
| View | Download | 0.321 | N/A | N/A | d.110.2 | GAF domain-like |
| View | Download | 0.320 | N/A | N/A | c.51.1 | Anticodon-binding domain of Class II aaRS |
| View | Download | 0.319 | N/A | N/A | c.49.1 | Pyruvate kinase, C-terminal domain |
| View | Download | 0.314 | N/A | N/A | d.110.4 | SNARE-like |
| View | Download | 0.312 | N/A | N/A | d.110.1 | Profilin (actin-binding protein) |
| View | Download | 0.302 | N/A | N/A | d.110.4 | SNARE-like |
| View | Download | 0.301 | N/A | N/A | d.204.1 | Ribosome binding protein Y (YfiA homologue) |
| View | Download | 0.300 | N/A | N/A | b.55.1 | PH domain-like |
| View | Download | 0.299 | N/A | N/A | d.110.4 | SNARE-like |
| View | Download | 0.295 | N/A | N/A | a.118.9 | ENTH/VHS domain |
| View | Download | 0.293 | N/A | N/A | d.110.1 | Profilin (actin-binding protein) |
| View | Download | 0.292 | N/A | N/A | c.47.1 | Thioredoxin-like |
| View | Download | 0.282 | N/A | N/A | d.110.4 | SNARE-like |
| View | Download | 0.280 | N/A | N/A | d.110.4 | SNARE-like |
| View | Download | 0.280 | N/A | N/A | c.47.1 | Thioredoxin-like |
| View | Download | 0.279 | N/A | N/A | d.110.1 | Profilin (actin-binding protein) |
| View | Download | 0.273 | N/A | N/A | a.39.1 | EF-hand |
| View | Download | 0.272 | N/A | N/A | d.58.26 | GHMP Kinase, C-terminal domain |
| View | Download | 0.272 | N/A | N/A | a.24.10 | Histidine-containing phosphotransfer domain, HPT domain |
| View | Download | 0.271 | N/A | N/A | d.91.1 | N-terminal domain of eukaryotic peptide chain release factor subunit 1, ERF1 |
| View | Download | 0.269 | N/A | N/A | a.24.12 | Outer surface protein C (OspC) |
| View | Download | 0.268 | N/A | N/A | d.91.1 | N-terminal domain of eukaryotic peptide chain release factor subunit 1, ERF1 |
| View | Download | 0.268 | N/A | N/A | d.93.1 | SH2 domain |
| View | Download | 0.266 | N/A | N/A | c.49.1 | Pyruvate kinase, C-terminal domain |
| View | Download | 0.262 | N/A | N/A | d.87.1 | FAD/NAD-linked reductases, dimerisation (C-terminal) domain |
| View | Download | 0.260 | N/A | N/A | d.92.2 | beta-N-acetylhexosaminidase-like domain |
| View | Download | 0.260 | N/A | N/A | b.55.1 | PH domain-like |
| View | Download | 0.259 | N/A | N/A | d.110.4 | SNARE-like |
| View | Download | 0.253 | N/A | N/A | a.74.1 | Cyclin-like |
| View | Download | 0.252 | N/A | N/A | b.55.1 | PH domain-like |
| View | Download | 0.251 | N/A | N/A | d.110.4 | SNARE-like |
| View | Download | 0.250 | N/A | N/A | c.78.2 | Aspartate/glutamate racemase |
| View | Download | 0.250 | N/A | N/A | b.55.1 | PH domain-like |
| View | Download | 0.246 | N/A | N/A | d.110.4 | SNARE-like |
| View | Download | 0.239 | N/A | N/A | b.55.1 | PH domain-like |
| View | Download | 0.232 | N/A | N/A | d.110.4 | SNARE-like |
| View | Download | 0.227 | N/A | N/A | d.134.1 | Sulfite reductase hemoprotein (SiRHP), domains 2 and 4 |
| View | Download | 0.227 | N/A | N/A | c.23.1 | CheY-like |
| View | Download | 0.227 | N/A | N/A | c.47.1 | Thioredoxin-like |
| View | Download | 0.226 | N/A | N/A | d.93.1 | SH2 domain |
| View | Download | 0.222 | N/A | N/A | d.204.1 | Ribosome binding protein Y (YfiA homologue) |
| View | Download | 0.221 | N/A | N/A | c.47.1 | Thioredoxin-like |
| View | Download | 0.218 | N/A | N/A | d.91.1 | N-terminal domain of eukaryotic peptide chain release factor subunit 1, ERF1 |
| View | Download | 0.217 | N/A | N/A | c.72.1 | Ribokinase-like |
| View | Download | 0.217 | N/A | N/A | c.47.2 | RNA 3'-terminal phosphate cyclase, RPTC, insert domain |
| View | Download | 0.217 | N/A | N/A | c.47.2 | RNA 3'-terminal phosphate cyclase, RPTC, insert domain |
| View | Download | 0.216 | N/A | N/A | c.47.1 | Thioredoxin-like |
| View | Download | 0.213 | N/A | N/A | a.74.1 | Cyclin-like |
| View | Download | 0.209 | N/A | N/A | a.118.11 | Cytochrome c oxidase subunit E |
| View | Download | 0.203 | N/A | N/A | c.58.1 | Aminoacid dehydrogenase-like, N-terminal domain |
| View | Download | 0.200 | N/A | N/A | a.177.1 | Sigma2 domain of RNA polymerase sigma factors |
| Term | Confidence | Notes |
| O-acyltransferase activity | 3.20415400376574 | bayes_pls_golite062009 |
| carnitine O-acyltransferase activity | 3.20101546976547 | bayes_pls_golite062009 |
| transferase activity, transferring acyl groups | 2.5133185343892 | bayes_pls_golite062009 |
| O-acetyltransferase activity | 1.89721072292762 | bayes_pls_golite062009 |
| carnitine O-acetyltransferase activity | 1.73532543051487 | bayes_pls_golite062009 |
| transferase activity | 1.53549002805559 | bayes_pls_golite062009 |
| S-acyltransferase activity | 1.4571562987488 | bayes_pls_golite062009 |
| catalytic activity | 1.4057670600405 | bayes_pls_golite062009 |
| transferase activity, transferring acyl groups other than amino-acyl groups | 1.33466655894478 | bayes_pls_golite062009 |
| acyltransferase activity | 1.32890060077614 | bayes_pls_golite062009 |
| binding | 1.0573980916647 | bayes_pls_golite062009 |
| dihydrolipoamide S-acyltransferase activity | 0.791271717033212 | bayes_pls_golite062009 |
| acetyltransferase activity | 0.743826754374996 | bayes_pls_golite062009 |
| dihydrolipoyllysine-residue acetyltransferase activity | 0.554321586879044 | bayes_pls_golite062009 |
| S-acetyltransferase activity | 0.534356421723053 | bayes_pls_golite062009 |
| protein binding | 0.142046790608097 | bayes_pls_golite062009 |
| succinyltransferase activity | 0.0687075977536176 | bayes_pls_golite062009 |
|
Region A: Residues: [132-213] |
1 11 21 31 41 51
| | | | | |
1 ERTPQLFRLA FLENQDFKLD EFKHHLVDFA LNLDTSNNAH VLNLIYNSLL YSNERVTIVA 60
61 DQFTQYLTAA LSDPSNCITK IS
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
SCOP Match |
SCOP Description | ||
| View | Download | 0.376 | d.9.1 | Interleukin 8-like chemokines |
| View | Download | 0.367 | d.58.3 | Protease propeptides/inhibitors |
| View | Download | 0.506 | d.17.2 | Copper amine oxidase, domains 1 and 2 |
| View | Download | 0.306 | a.48.3 | Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 |
| View | Download | 0.294 | d.93.1 | SH2 domain |
| View | Download | 0.289 | d.101.1 | Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domains 2 and 5 |
| View | Download | 0.243 | d.93.1 | SH2 domain |
| View | Download | 0.229 | d.9.2 | Description not found. |
| View | Download | 0.223 | a.3.1 | Cytochrome c |
| View | Download | 0.219 | d.19.1 | MHC antigen-recognition domain |
| View | Download | 0.204 | a.29.4 | RecG, N-terminal domain |
| Term | Confidence | Notes |
| fatty acid ligase activity | 3.20885084723265 | bayes_pls_golite062009 |
| long-chain fatty acid-CoA ligase activity | 3.09442488073562 | bayes_pls_golite062009 |
| ligase activity | 2.49556073715112 | bayes_pls_golite062009 |
| ligase activity, forming carbon-sulfur bonds | 2.12147420637201 | bayes_pls_golite062009 |
| catalytic activity | 1.83545185797733 | bayes_pls_golite062009 |
| transcription regulator activity | 1.30923531749766 | bayes_pls_golite062009 |
| binding | 1.1019187064081 | bayes_pls_golite062009 |
| acetate-CoA ligase activity | 0.546415900680738 | bayes_pls_golite062009 |
|
Region A: Residues: [214-230] |
1 11 21 31 41 51
| | | | | |
1 LITASSKDSL PDPTKNL
|
|
Region B: Residues: [486-697] |
1 11 21 31 41 51
| | | | | |
1 TQDDIGTPGR LAEWMSKYGC TVTHLTPAMG QLLTAQATTP FPKLHHAFFV GDILTKRDCL 60
61 RLQTLAENCR IVNMYGTTET QRAVSYFEVK SKNDDPNFLK KLKDVMPAGK GMLNVQLLVV 120
121 NRNDRTQICG IGEIGEIYVR AGGLAEGYRG LPELNKEKFV NNWFVEKDHW NYLDKDNGEP 180
181 WRQFWLGPRD RLYRTGDLGR YLPNGDCECC GR
|
| Detection Method: | |
| Confidence: | 635.0103 |
| Match: | 1amuA_ |
| Description: | Phenylalanine activating domain of gramicidin synthetase 1 |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| acyl carrier activity | 1.48628066075615 | bayes_pls_golite062009 |
| binding | 1.3440503335733 | bayes_pls_golite062009 |
| transporter activity | 0.13827434266385 | bayes_pls_golite062009 |
| catalytic activity | 0.037428828577411 | bayes_pls_golite062009 |
|
Region A: Residues: [231-274] |
1 11 21 31 41 51
| | | | | |
1 GWCDFVGCIH DIFQDNAEAF PERTCVVETP TLNSDKSRSF TYRD
|
|
Region B: Residues: [423-485] |
1 11 21 31 41 51
| | | | | |
1 GSEGIPKGVL GRHFSLAYYF NWMSKRFNLT ENDKFTMLSG IAHDPIQRDM FTPLFLGAQL 60
61 YVP
|
|
Region C: Residues: [698-843] |
1 11 21 31 41 51
| | | | | |
1 ADDQVKIRGF RIELGEIDTH ISQHPLVREN ITLVRKNADN EPTLITFMVP RFDKPDDLSK 60
61 FQSDVPKEVE TDPIVKGLIG YHLLSKDIRT FLKKRLASYA MPSLIVVMDK LPLNPNGKVD 120
121 KPKLQFPTPK QLNLVAENTV SETDDS
|
| Detection Method: | |
| Confidence: | 635.0103 |
| Match: | 1amuA_ |
| Description: | Phenylalanine activating domain of gramicidin synthetase 1 |
| Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| carnitine O-acyltransferase activity | 3.8017528139322 | bayes_pls_golite062009 |
| O-acyltransferase activity | 3.7101056995294 | bayes_pls_golite062009 |
| transferase activity, transferring acyl groups | 2.98258255788559 | bayes_pls_golite062009 |
| O-acetyltransferase activity | 2.37098434941789 | bayes_pls_golite062009 |
| carnitine O-acetyltransferase activity | 2.29021577279172 | bayes_pls_golite062009 |
| S-acyltransferase activity | 2.05222019970921 | bayes_pls_golite062009 |
| transferase activity, transferring acyl groups other than amino-acyl groups | 1.82057686950663 | bayes_pls_golite062009 |
| acyltransferase activity | 1.8182709252044 | bayes_pls_golite062009 |
| transferase activity | 1.78692523095641 | bayes_pls_golite062009 |
| catalytic activity | 1.51562638409295 | bayes_pls_golite062009 |
| dihydrolipoamide S-acyltransferase activity | 1.36884408592523 | bayes_pls_golite062009 |
| acetyltransferase activity | 1.12787027896966 | bayes_pls_golite062009 |
| dihydrolipoyllysine-residue acetyltransferase activity | 1.1171542351657 | bayes_pls_golite062009 |
| S-acetyltransferase activity | 1.08950177361576 | bayes_pls_golite062009 |
| binding | 0.999555841397607 | bayes_pls_golite062009 |
| succinyltransferase activity | 0.542498759931255 | bayes_pls_golite062009 |
| protein binding | 0.104367069798378 | bayes_pls_golite062009 |
|
Region A: Residues: [275-422] |
1 11 21 31 41 51
| | | | | |
1 INRTSNIVAH YLIKTGIKRG DVVMIYSSRG VDLMVCVMGV LKAGATFSVI DPAYPPARQT 60
61 IYLGVAKPRG LIVIRAAGQL DQLVEDYIND ELEIVSRINS IAIQENGTIE GGKLDNGEDV 120
121 LAPYDHYKDT RTGVVVGPDS NPTLSFTS
|
| Detection Method: | |
| Confidence: | 635.0103 |
| Match: | 1amuA_ |
| Description: | Phenylalanine activating domain of gramicidin synthetase 1 |
| Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [844-936] |
1 11 21 31 41 51
| | | | | |
1 QFTNVEREVR DLWLSILPTK PASVSPDDSF FDLGGHSILA TKMIFTLKKK LQVDLPLGTI 60
61 FKYPTIKAFA AEIDRIKSSG GSSQGEVVEN VTA
|
| Detection Method: | |
| Confidence: | 70.440336 |
| Match: | 1dnyA_ |
| Description: | Peptidyl carrier protein (PCP), thioester domain |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [937-1188] |
1 11 21 31 41 51
| | | | | |
1 NYAEDAKKLV ETLPSSYPSR EYFVEPNSAE GKTTINVFVT GVTGFLGSYI LADLLGRSPK 60
61 NYSFKVFAHV RAKDEEAAFA RLQKAGITYG TWNEKFASNI KVVLGDLSKS QFGLSDEKWM 120
121 DLANTVDIII HNGALVHWVY PYAKLRDPNV ISTINVMSLA AVGKPKFFDF VSSTSTLDTE 180
181 YYFNLSDKLV SEGKPGILES DDLMNSASGL TGGYGQSKWA AEYIIRRAGE RGLRGCIVRP 240
241 GYVTGASANG SS
|
| Detection Method: | |
| Confidence: | 6.045757 |
| Match: | 1l5aA_ |
| Description: | VibH |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [1189-1392] |
1 11 21 31 41 51
| | | | | |
1 NTDDFLLRFL KGSVQLGKIP DIENSVNMVP VDHVARVVVA TSLNPPKENE LAVAQVTGHP 60
61 RILFKDYLYT LHDYGYDVEI ESYSKWKKSL EASVIDRNEE NALYPLLHMV LDNLPESTKA 120
121 PELDDRNAVA SLKKDTAWTG VDWSNGIGVT PEEVGIYIAF LNKVGFLPPP THNDKLPLPS 180
181 IELTQAQISL VASGAGARGS SAAA
|
| Detection Method: | |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
