Protein Overview: gi|23506932

General Information:
Name(s) found:	gi\|23506932 [NCBI NR]
Description(s) found: Found 3 descriptions. SHOW ALL	gi\|23506932\|gb\|AAN31950.1\| aminoadipate-semialdehyde dehydrogenase; Lys2p [Cloning vector YDp-K] [NCBI NR]
Organism:	Cloning vector YDp-K
Length:	1392 amino acids
Gene Ontology:
Cellular Component:	NONE FOUND
Biological Process:	NONE FOUND
Molecular Function:	NONE FOUND

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTNEKVWIEK LDNPTLSVLP HDFLRPQQEP YTKQATYSLQ LPQLDVPHDS FSNKYAVALS  60
   61 VWAALIYRVT GDDDIVLYIA NNKILRFNIQ PTWSFNELYS TINNELNKLN SIEANFSFDE 120
  121 LAEKIQSCQD LERTPQLFRL AFLENQDFKL DEFKHHLVDF ALNLDTSNNA HVLNLIYNSL 180
  181 LYSNERVTIV ADQFTQYLTA ALSDPSNCIT KISLITASSK DSLPDPTKNL GWCDFVGCIH 240
  241 DIFQDNAEAF PERTCVVETP TLNSDKSRSF TYRDINRTSN IVAHYLIKTG IKRGDVVMIY 300
  301 SSRGVDLMVC VMGVLKAGAT FSVIDPAYPP ARQTIYLGVA KPRGLIVIRA AGQLDQLVED 360
  361 YINDELEIVS RINSIAIQEN GTIEGGKLDN GEDVLAPYDH YKDTRTGVVV GPDSNPTLSF 420
  421 TSGSEGIPKG VLGRHFSLAY YFNWMSKRFN LTENDKFTML SGIAHDPIQR DMFTPLFLGA 480
  481 QLYVPTQDDI GTPGRLAEWM SKYGCTVTHL TPAMGQLLTA QATTPFPKLH HAFFVGDILT 540
  541 KRDCLRLQTL AENCRIVNMY GTTETQRAVS YFEVKSKNDD PNFLKKLKDV MPAGKGMLNV 600
  601 QLLVVNRNDR TQICGIGEIG EIYVRAGGLA EGYRGLPELN KEKFVNNWFV EKDHWNYLDK 660
  661 DNGEPWRQFW LGPRDRLYRT GDLGRYLPNG DCECCGRADD QVKIRGFRIE LGEIDTHISQ 720
  721 HPLVRENITL VRKNADNEPT LITFMVPRFD KPDDLSKFQS DVPKEVETDP IVKGLIGYHL 780
  781 LSKDIRTFLK KRLASYAMPS LIVVMDKLPL NPNGKVDKPK LQFPTPKQLN LVAENTVSET 840
  841 DDSQFTNVER EVRDLWLSIL PTKPASVSPD DSFFDLGGHS ILATKMIFTL KKKLQVDLPL 900
  901 GTIFKYPTIK AFAAEIDRIK SSGGSSQGEV VENVTANYAE DAKKLVETLP SSYPSREYFV 960
  961 EPNSAEGKTT INVFVTGVTG FLGSYILADL LGRSPKNYSF KVFAHVRAKD EEAAFARLQK1020
 1021 AGITYGTWNE KFASNIKVVL GDLSKSQFGL SDEKWMDLAN TVDIIIHNGA LVHWVYPYAK1080
 1081 LRDPNVISTI NVMSLAAVGK PKFFDFVSST STLDTEYYFN LSDKLVSEGK PGILESDDLM1140
 1141 NSASGLTGGY GQSKWAAEYI IRRAGERGLR GCIVRPGYVT GASANGSSNT DDFLLRFLKG1200
 1201 SVQLGKIPDI ENSVNMVPVD HVARVVVATS LNPPKENELA VAQVTGHPRI LFKDYLYTLH1260
 1261 DYGYDVEIES YSKWKKSLEA SVIDRNEENA LYPLLHMVLD NLPESTKAPE LDDRNAVASL1320
 1321 KKDTAWTGVD WSNGIGVTPE EVGIYIAFLN KVGFLPPPTH NDKLPLPSIE LTQAQISLVA1380
 1381 SGAGARGSSA AA

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Microscopy / Localization Data

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No microscopy data found in the PDR for this protein.

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..131]	MSA	1.206982	View MSA. No confident structure predictions are available.
2	View Details	[132..213]	deduced	N/A	No confident structure predictions are available.
3	View Details	[214..230] [486..697]	PSI-BLAST	635.0103	Phenylalanine activating domain of gramicidin synthetase 1
4	View Details	[231..274] [423..485] [698..843]	PSI-BLAST	635.0103	Phenylalanine activating domain of gramicidin synthetase 1
5	View Details	[275..422]	PSI-BLAST	635.0103	Phenylalanine activating domain of gramicidin synthetase 1
6	View Details	[844..936]	PSI-BLAST	70.440336	Peptidyl carrier protein (PCP), thioester domain
7	View Details	[937..1188]	PSI-BLAST	6.045757	VibH
8	View Details	[1189..1392]	MSA	1.087943	View MSA. No confident structure predictions are available.

Functions predicted (by domain):

#

Gene Ontology predictions

1

Term	Confidence	Notes
O-acyltransferase activity	3.20415400376574	bayes_pls_golite062009
carnitine O-acyltransferase activity	3.20101546976547	bayes_pls_golite062009
transferase activity, transferring acyl groups	2.5133185343892	bayes_pls_golite062009
O-acetyltransferase activity	1.89721072292762	bayes_pls_golite062009
carnitine O-acetyltransferase activity	1.73532543051487	bayes_pls_golite062009
transferase activity	1.53549002805559	bayes_pls_golite062009
S-acyltransferase activity	1.4571562987488	bayes_pls_golite062009
catalytic activity	1.4057670600405	bayes_pls_golite062009
transferase activity, transferring acyl groups other than amino-acyl groups	1.33466655894478	bayes_pls_golite062009
acyltransferase activity	1.32890060077614	bayes_pls_golite062009
binding	1.0573980916647	bayes_pls_golite062009
dihydrolipoamide S-acyltransferase activity	0.791271717033212	bayes_pls_golite062009
acetyltransferase activity	0.743826754374996	bayes_pls_golite062009
dihydrolipoyllysine-residue acetyltransferase activity	0.554321586879044	bayes_pls_golite062009
S-acetyltransferase activity	0.534356421723053	bayes_pls_golite062009
protein binding	0.142046790608097	bayes_pls_golite062009
succinyltransferase activity	0.0687075977536176	bayes_pls_golite062009

2

Term	Confidence	Notes
fatty acid ligase activity	3.20885084723265	bayes_pls_golite062009
long-chain fatty acid-CoA ligase activity	3.09442488073562	bayes_pls_golite062009
ligase activity	2.49556073715112	bayes_pls_golite062009
ligase activity, forming carbon-sulfur bonds	2.12147420637201	bayes_pls_golite062009
catalytic activity	1.83545185797733	bayes_pls_golite062009
transcription regulator activity	1.30923531749766	bayes_pls_golite062009
binding	1.1019187064081	bayes_pls_golite062009
acetate-CoA ligase activity	0.546415900680738	bayes_pls_golite062009

3

Term	Confidence	Notes
acyl carrier activity	1.48628066075615	bayes_pls_golite062009
binding	1.3440503335733	bayes_pls_golite062009
transporter activity	0.13827434266385	bayes_pls_golite062009
catalytic activity	0.037428828577411	bayes_pls_golite062009

4

Term	Confidence	Notes
carnitine O-acyltransferase activity	3.8017528139322	bayes_pls_golite062009
O-acyltransferase activity	3.7101056995294	bayes_pls_golite062009
transferase activity, transferring acyl groups	2.98258255788559	bayes_pls_golite062009
O-acetyltransferase activity	2.37098434941789	bayes_pls_golite062009
carnitine O-acetyltransferase activity	2.29021577279172	bayes_pls_golite062009
S-acyltransferase activity	2.05222019970921	bayes_pls_golite062009
transferase activity, transferring acyl groups other than amino-acyl groups	1.82057686950663	bayes_pls_golite062009
acyltransferase activity	1.8182709252044	bayes_pls_golite062009
transferase activity	1.78692523095641	bayes_pls_golite062009
catalytic activity	1.51562638409295	bayes_pls_golite062009
dihydrolipoamide S-acyltransferase activity	1.36884408592523	bayes_pls_golite062009
acetyltransferase activity	1.12787027896966	bayes_pls_golite062009
dihydrolipoyllysine-residue acetyltransferase activity	1.1171542351657	bayes_pls_golite062009
S-acetyltransferase activity	1.08950177361576	bayes_pls_golite062009
binding	0.999555841397607	bayes_pls_golite062009
succinyltransferase activity	0.542498759931255	bayes_pls_golite062009
protein binding	0.104367069798378	bayes_pls_golite062009

5

No functions predicted.

6

No functions predicted.

7

No functions predicted.

8

No functions predicted.

Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

Philius Transmembrane Prediction:

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.96

Source: Reynolds et al. (2008)

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle