YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|30264592, gi\|...
Organism:	Bacillus anthracis str. Ames
Length:	563 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|30264592, gi|....

Description	E-value	Query Range	Subject Range
gi\|49333026, gi\|... - gi\|49481470\|ref\|YP_038577.1\| acyl-CoA synthetase [Bacillus thuringiensis serovar konkukian str. 97-2...	0.0	[1..563]	[1..563]
gi\|52140978, gi\|... - gi\|52140978\|ref\|YP_085852.1\| acyl-CoA synthetase [Bacillus cereus E33L], gi\|51974447\|gb\|AAU15997.1\| ...	0.0	[1..563]	[1..563]
gi\|42739628, gi\|... - gi\|42783699\|ref\|NP_980946.1\| acyl-CoA synthetase [Bacillus cereus ATCC 10987], gi\|42739628\|gb\|AAS435...	0.0	[3..563]	[1..561]
gi\|163864454, gi... - gi\|89205308\|ref\|ZP_01183879.1\| AMP-dependent synthetase and ligase [Bacillus weihenstephanensis KBAB...	0.0	[3..563]	[1..561]
gi\|65321891 - gi\|65321891\|ref\|ZP_00394850.1\| COG0318: Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II [Baci...	0.0	[1..563]	[1..563]
gi\|25293423 - pir\|\|H84037 long-chain fatty-acid-CoA ligase BH3104 [imported] - Bacillus halodurans (strain C-125) gi\|15615666, gi\|... - gi\|15615666\|ref\|NP_243970.1\| long-chain fatty-acid-CoA ligase [Bacillus halodurans C-125], gi\|101757...	0.0	[1..560]	[1..561]
gi\|89200353, gi\|... - gi\|89200353\|ref\|ZP_01179107.1\| AMP-dependent synthetase and ligase [Bacillus cereus subsp. cytotoxis...	0.0	[3..549]	[16..562]
gi\|56421225, gi\|... - gi\|56421225\|ref\|YP_148543.1\| long chain acyl-CoA synthetase [Geobacillus kaustophilus HTA426], gi\|56...	0.0	[3..558]	[1..558]
gi\|55981432, gi\|... - gi\|55981432\|ref\|YP_144729.1\| long-chain-fatty-acid--CoA ligase [Thermus thermophilus HB8], gi\|557728...	0.0	[4..557]	[6..559]
gi\|77996178, gi\|... - gi\|78044063\|ref\|YP_360551.1\| long-chain-fatty-acid--CoA ligase [Carboxydothermus hydrogenoformans Z-...	0.0	[4..558]	[7..544]

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Predicted Domain #1

Region A:
Residues: [1-563]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKVEKPWLKS YPEEIPSTIS YDIQPLHKYV EQMASRYPEK KALHFLGKDI TFSVFHDKVK  60
   61 RFANYLQKLG VGKGDRVAIM LPNCPQAVIG YYGTLLAGGI VVQTNPLYTE RELEYQLHDS 120
  121 GAKVILCLDL VFPRVTNVQS ATKIEHVIVT RIADFLPFPK NLLYPFVQKK QSNLVVKVSE 180
  181 SETIHLWNSV EKEVNTGVEV PCDPENDLAL LQYTGGTTGF PKGVMLTHKN LVSNTLMGVQ 240
  241 WLYNCKEGEE VVLGVLPFFH VYGMTAVMNL SIMQGYKMVL IPKFDMKMVF EAIKKHKVTL 300
  301 FPGAPTIYIA LLNSPLLKEY DISSIRACIS GSAPLPVEVQ EKFETVTGGK LVEGYGLTES 360
  361 SPVTHSNFLW EKRVPGSIGV PWPDTEAMIM SLETGEALRP GEIGEIVVKG PQIMKGYWNK 420
  421 PEETAAVLQD GWLHTGDVGY MDEDGFFYVK DRKKDMIVAS GFNVYPREVE EVLYEHEKVQ 480
  481 EVVTIGVPDP YRGETVKAFV VLKEGTECSE EELNQFARKY LAAYKVPKVY EFRDELPKTT 540
  541 VGKILRRVLI EEEKRKNEDE QTG

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	97.522879
Match:	1ba3A
Description:	FIREFLY LUCIFERASE IN COMPLEX WITH BROMOFORM
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
ligase activity, forming carbon-sulfur bonds	5.10123876514454	bayes_pls_golite062009
fatty acid ligase activity	4.83067429373059	bayes_pls_golite062009
long-chain fatty acid-CoA ligase activity	4.72692389032116	bayes_pls_golite062009
acetate-CoA ligase activity	4.48129067128523	bayes_pls_golite062009
acid-thiol ligase activity	4.28278725989432	bayes_pls_golite062009
CoA-ligase activity	4.12850865352867	bayes_pls_golite062009
Photinus-luciferin 4-monooxygenase (ATP-hydrolyzing) activity	2.74744781333102	bayes_pls_golite062009
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases)	2.74744781333102	bayes_pls_golite062009
luciferin monooxygenase activity	2.67396462766343	bayes_pls_golite062009
ligase activity	2.49556073715112	bayes_pls_golite062009
transcription regulator activity	2.31193176808353	bayes_pls_golite062009
catalytic activity	1.83545185797733	bayes_pls_golite062009
binding	1.5312519256537	bayes_pls_golite062009
transporter activity	1.29780964436121	bayes_pls_golite062009
transcription repressor activity	1.2638869228049	bayes_pls_golite062009
branched-chain aliphatic amino acid transmembrane transporter activity	1.18574343794772	bayes_pls_golite062009
organic acid transmembrane transporter activity	1.12905679329698	bayes_pls_golite062009
carboxylic acid transmembrane transporter activity	1.11961482903654	bayes_pls_golite062009
transmembrane transporter activity	1.07143339827205	bayes_pls_golite062009
substrate-specific transporter activity	1.03753946113449	bayes_pls_golite062009
AMP binding	0.778227294974491	bayes_pls_golite062009
amine transmembrane transporter activity	0.75860693537743	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	0.54797726647835	bayes_pls_golite062009
transferase activity, transferring acyl groups	0.464663038956639	bayes_pls_golite062009
active transmembrane transporter activity	0.251681382273558	bayes_pls_golite062009
primary active transmembrane transporter activity	0.225448500718996	bayes_pls_golite062009
P-P-bond-hydrolysis-driven transmembrane transporter activity	0.216579620878492	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances	0.177812048124158	bayes_pls_golite062009
ATPase activity, coupled to movement of substances	0.174283007890308	bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of substances	0.173963339749644	bayes_pls_golite062009
nucleoside-triphosphatase activity	0.0401881910649647	bayes_pls_golite062009
pyrophosphatase activity	0.0047964784091391	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: