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View Structure Prediction Details

Protein: gi|30259003, gi|...
Organism: Bacillus anthracis str. Ames
Length: 706 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|30259003, gi|....

Description E-value Query
Range
Subject
Range
gi|51974695, gi|... - gi|52141226|ref|YP_085603.1| penicillin-binding protein [Bacillus cereus E33L], gi|51974695|gb|AAU16...
0.0 [1..706] [1..706]
gi|42739328, gi|... - gi|42783399|ref|NP_980646.1| penicillin-binding protein [Bacillus cereus ATCC 10987], gi|42739328|gb...
0.0 [13..706] [13..706]
gi|47567835, gi|... - gi|47567835|ref|ZP_00238543.1| penicillin-binding protein 3 [Bacillus cereus G9241], gi|47555512|gb|...
0.0 [1..706] [1..707]
gi|29897910, gi|... - gi|30022353|ref|NP_833984.1| penicillin-binding protein [Bacillus cereus ATCC 14579], gi|29897910|gb...
0.0 [1..706] [1..708]
gi|49481285, gi|... - gi|49481285|ref|YP_038332.1| penicillin-binding protein [Bacillus thuringiensis serovar konkukian st...
0.0 [1..706] [1..708]
gi|65321650 - gi|65321650|ref|ZP_00394609.1| COG0768: Cell division protein FtsI/penicillin-binding protein 2 [Bac...
0.0 [28..706] [1..679]
gi|75759756, gi|... - gi|75759756|ref|ZP_00739835.1| Penicillin binding protein transpeptidase [Bacillus thuringiensis ser...
0.0 [13..687] [19..694]
gi|152025458, gi... - gi|89201791|ref|ZP_01180526.1| Penicillin-binding protein, transpeptidase:Penicillin-binding protein...
0.0 [13..706] [10..705]
gi|163942032, gi... - gi|89207542|ref|ZP_01186081.1| Penicillin-binding protein, transpeptidase:Penicillin-binding protein...
0.0 [13..705] [15..710]

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Predicted Domain #1
Region A:
Residues: [1-706]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSKKQKQQKK KTHVPFRLNV LFFCVFLMFS AVIVRLGYVQ IVRGEEYKNE VERKENSTIS  60
   61 NPVPRGKIFD RYGRPVVDNA AVRTITFTKM KGSTAEARLE TAKKLADLIE VPTNKLTDRD 120
  121 KKDYWLAIHK EEAKEKITNK DRQEFKDKKI DDKELDERQR NRVTEEEVNQ LSAKDLEVLA 180
  181 IKSKMDGGYA MTPQVIKKDA TEQEYAIISE NLATLPGVDT NVDWDRKYIY DDLFRSVLGG 240
  241 VSTSDEGLPR ERLDYYLVRD YNRNDRVGKS YLEQQYEDSL HGNKAEVRNV TDKNGNILET 300
  301 INVSKGQSGN NLNLTIDMEL QKRVEEIITK NLLRYKGGQP YLDRAFVVMM NPKNGEVLSM 360
  361 AGKQLVEENG ETKVQDFALG TMTSSYPMGS TVKGATVLTG YQTGAIQPGS VQLDEPIRLK 420
  421 GTPPKSSWKT MGYINDLTAL KMSSNVYMFK TAMNIAGVQY VRGGTLDIPQ KAFDTMRYYF 480
  481 GQFGLGVKTG IDLPNESAGQ TGRGNQPGFL LDLSIGQYDT YTPLQLAQYV STIANGGYRM 540
  541 QPQVVKEIRQ PSAKQDEVGK VVHSMEPKVL NRIDMPESQI KRVQEGFRQV FNDSGGTAAK 600
  601 YFTGAPYKAA GKTGTAQTVY GGDKEIGKKA NGERKETYNL TLVGYAPLED PEVAFSVVVP 660
  661 WVDDKSGING YISRDIMDAY FDLKKVENGE ATKDEIDKKN KEQDDE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 89.522879
Match: 1rp5A
Description: PBP2x from Streptococcus pneumoniae strain 5259 with reduced susceptibility to beta-lactam antibiotics
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
serine-type D-Ala-D-Ala carboxypeptidase activity 3.37745387761459 bayes_pls_golite062009
penicillin binding 3.16077730467133 bayes_pls_golite062009
serine-type carboxypeptidase activity 3.02516915958448 bayes_pls_golite062009
serine-type exopeptidase activity 2.98959517344587 bayes_pls_golite062009
carboxypeptidase activity 2.34154596924818 bayes_pls_golite062009
catalytic activity 2.2253600206851 bayes_pls_golite062009
drug binding 2.00354593744547 bayes_pls_golite062009
hydrolase activity 1.60399436620363 bayes_pls_golite062009
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 1.50532593223645 bayes_pls_golite062009
peptidase activity 1.19806036181576 bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides 0.9301046317358 bayes_pls_golite062009
serine hydrolase activity 0.7685205097747 bayes_pls_golite062009
serine-type peptidase activity 0.76747998716775 bayes_pls_golite062009
exopeptidase activity 0.373099549833319 bayes_pls_golite062009

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