YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|24372509, gi\|...
Organism:	Shewanella oneidensis MR-1
Length:	424 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|24372509, gi|....

Description	E-value	Query Range	Subject Range
gi\|113890191, gi... - gi\|78688849\|ref\|ZP_00853516.1\| proton/glutamate symporter [Shewanella sp. MR-7], gi\|78511849\|gb\|EAP2...	406.0	[0..1]	[422..17]
gi\|117921800, gi... - gi\|78684617\|ref\|ZP_00849400.1\| proton/glutamate symporter [Shewanella sp. ANA-3], gi\|78507554\|gb\|EAP...	406.0	[0..1]	[422..17]
gi\|113883792, gi... - gi\|82495135\|ref\|ZP_00880713.1\| proton/glutamate symporter [Shewanella sp. MR-4], gi\|82406971\|gb\|EAP4...	401.0	[0..1]	[419..17]
gi\|82742069, gi\|... - gi\|82742069\|ref\|ZP_00904774.1\| proton/glutamate symporter [Shewanella sp. W3-18-1], gi\|82720597\|gb\|E... gi\|145563657, gi... - gi\|77813066\|ref\|ZP_00812347.1\| Sodium:dicarboxylate symporter [Shewanella putrefaciens CN-32], gi\|77... gi\|124545694, gi... - gi\|124545694\|ref\|ZP_01704869.1\| sodium:dicarboxylate symporter [Shewanella putrefaciens 200], gi\|124...	396.0	[0..1]	[418..17]
gi\|114637062 - gi\|114637062\|ref\|XP_508369.2\| PREDICTED: solute carrier family 1, member 2 [Pan troglodytes]	392.0	[0..2]	[423..176]
gi\|68541131, gi\|... - gi\|68541131\|ref\|ZP_00580878.1\| Sodium:dicarboxylate symporter [Shewanella baltica OS155], gi\|6852127...	390.0	[0..1]	[421..17]
gi\|113909753, gi... - gi\|160876777\|ref\|YP_001556093.1\| sodium:dicarboxylate symporter [Shewanella baltica OS195], gi\|16086...	389.0	[0..1]	[421..17]
gi\|68364150 - gi\|68364150\|ref\|XP_689294.1\| PREDICTED: similar to solute carrier family 1 (glial high affinity glut...	387.0	[0..10]	[423..127]
gi\|68545559, gi\|... - gi\|68545559\|ref\|ZP_00585109.1\| Sodium:dicarboxylate symporter [Shewanella amazonensis SB2B], gi\|6851...	384.0	[0..3]	[415..16]
gi\|127511677, gi... - gi\|78365809\|ref\|ZP_00836093.1\| Sodium:dicarboxylate symporter [Shewanella sp. PV-4], gi\|78362032\|gb\|...	383.0	[0..1]	[412..18]

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Predicted Domain #1

Region A:
Residues: [1-424]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSVPLWLQIF VGMVLGILVG VTLGEQASYL KPIGTLFVNT IKMLIVPLVF CSLIVGVTSM  60
   61 EDTAKMGRIG FKSFSFYLCT TAIAISLGLV VGYVIQPGAG VPLLQHEAVN TAKEVPSVMQ 120
  121 TLIDIVPTNP VAALASGQIL QVIVFAVALG IALVLIGDHG KPAIKVFESL AEAMYKLTDM 180
  181 VMKLAPYGVF GLMAWVAGEY GIDMLWPLIK VIIAVYIGCI IHVLGFYSIV LRLFAKLNPL 240
  241 HFFKGISNAM AVAFTTSSSA GTLPASMKCA SEYLGVNKKI SSFVLPLGTT INMDGTALYQ 300
  301 GVTALFVAQA FGIDLTWVDY LTIILTATLA SIGTAGVPGA GLVMLTLVLS TVGLPLEGVA 360
  361 LIAGIDRILD MARTVVNVSG DLVATTVIAK SENELDVEHY NADMVQSAVI AEQNAANESA 420
  421 ATQR

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	86.045757
Match:	1xfhA
Description:	Structure of glutamate transporter homolog from Pyrococcus horikoshii
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
high-affinity glutamate transmembrane transporter activity	9.03564241021137	bayes_pls_golite062009
dicarboxylic acid transmembrane transporter activity	8.28237742051097	bayes_pls_golite062009
L-hydroxyproline transmembrane transporter activity	8.15113968525681	bayes_pls_golite062009
serine transmembrane transporter activity	8.15113968525681	bayes_pls_golite062009
alanine transmembrane transporter activity	8.15113968525681	bayes_pls_golite062009
L-threonine transmembrane transporter activity	8.15113968525681	bayes_pls_golite062009
L-serine transmembrane transporter activity	8.15113968525681	bayes_pls_golite062009
L-proline transmembrane transporter activity	8.15113968525681	bayes_pls_golite062009
L-alanine transmembrane transporter activity	8.15113968525681	bayes_pls_golite062009
L-aspartate transmembrane transporter activity	6.32804156021168	bayes_pls_golite062009
carboxylic acid transmembrane transporter activity	6.20769381184606	bayes_pls_golite062009
organic acid transmembrane transporter activity	6.19258658226115	bayes_pls_golite062009
anion:cation symporter activity	5.39486898992441	bayes_pls_golite062009
transporter activity	5.14616859489508	bayes_pls_golite062009
L-cystine transmembrane transporter activity	5.11451286998367	bayes_pls_golite062009
substrate-specific transporter activity	5.08516306839475	bayes_pls_golite062009
transmembrane transporter activity	5.06400974103865	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	5.03536308870823	bayes_pls_golite062009
ion transmembrane transporter activity	4.56245375639148	bayes_pls_golite062009
acidic amino acid transmembrane transporter activity	4.55490142908046	bayes_pls_golite062009
L-glutamate transmembrane transporter activity	4.55490142908046	bayes_pls_golite062009
cation transmembrane transporter activity	4.38524103588396	bayes_pls_golite062009
active transmembrane transporter activity	4.37939766329509	bayes_pls_golite062009
sulfur amino acid transmembrane transporter activity	4.37598805288869	bayes_pls_golite062009
secondary active transmembrane transporter activity	3.93820513423101	bayes_pls_golite062009
amine transmembrane transporter activity	3.7335977004076	bayes_pls_golite062009
L-amino acid transmembrane transporter activity	3.55306444119183	bayes_pls_golite062009
solute:cation symporter activity	3.47181854698038	bayes_pls_golite062009
symporter activity	3.47181854698038	bayes_pls_golite062009
organic acid:sodium symporter activity	3.44677545809568	bayes_pls_golite062009
amino acid transmembrane transporter activity	3.22640982674356	bayes_pls_golite062009
solute:hydrogen symporter activity	3.11518167297447	bayes_pls_golite062009
neutral amino acid transmembrane transporter activity	2.88609411192338	bayes_pls_golite062009
C4-dicarboxylate transmembrane transporter activity	2.522484225611	bayes_pls_golite062009
anion transmembrane transporter activity	2.02127810434029	bayes_pls_golite062009
solute:sodium symporter activity	1.76557983021416	bayes_pls_golite062009
protein binding	1.39188421476117	bayes_pls_golite062009
binding	1.33552537079117	bayes_pls_golite062009
amine binding	1.22219692417544	bayes_pls_golite062009
amino acid binding	1.0487791191866	bayes_pls_golite062009
cation:amino acid symporter activity	0.85052491897986	bayes_pls_golite062009
glutamate:sodium symporter activity	0.553718735358201	bayes_pls_golite062009
monocarboxylic acid transmembrane transporter activity	0.31624582149961	bayes_pls_golite062009
neurotransmitter transporter activity	0.25304246415333	bayes_pls_golite062009
passive transmembrane transporter activity	0.119412711778045	bayes_pls_golite062009
channel activity	0.119412711778045	bayes_pls_golite062009
substrate-specific channel activity	0.0999184515491418	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: