| Protein: | TRE1_YEAST |
| Organism: | Saccharomyces cerevisiae S288c |
| Length: | 783 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TRE1_YEAST.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..783] | [1..783] |
|
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0.0 | [31..781] | [20..797] |
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0.0 | [31..781] | [20..800] |
|
Region A: Residues: [1-136] |
1 11 21 31 41 51
| | | | | |
1 MVNTRGYTTL PNVEEPANNS QDELNSQDFE QAIGMPSEPP VYVEEMGMEE PQAPEAFSEK 60
61 VQRFRMCFEN NVVIPVKKNV VDPLAQMISL ASEKFDLFLS KIGNVMVMRR IFYIMMMSII 120
121 AALIIASDRL PNGKAR
|
| Detection Method: |  |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
SCOP Match |
SCOP Description | ||
| View | Download | 0.581 | a.27.1 | Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases |
| View | Download | 0.621 | d.79.2 | Tubulin/Dihydroxyacetone kinase C-terminal domain |
| View | Download | 0.621 | d.79.2 | Tubulin/Dihydroxyacetone kinase C-terminal domain |
| View | Download | 0.581 | a.27.1 | Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases |
| View | Download | 0.567 | a.48.1 | N-terminal domain of cbl (N-cbl) |
| View | Download | 0.567 | a.48.1 | N-terminal domain of cbl (N-cbl) |
| View | Download | 0.567 | d.79.2 | Tubulin/Dihydroxyacetone kinase C-terminal domain |
| View | Download | 0.537 | a.23.1 | HSC20 (HSCB), C-terminal oligomerisation domain |
| View | Download | 0.537 | a.23.1 | HSC20 (HSCB), C-terminal oligomerisation domain |
| View | Download | 0.499 | a.63.1 | Apolipophorin-III |
| View | Download | 0.493 | a.25.2 | Thermoplasma ferritin-like 4-helical bundle |
| View | Download | 0.487 | a.24.3 | Cytochromes |
| View | Download | 0.485 | a.7.8 | GAT domain |
| View | Download | 0.473 | a.24.9 | alpha-catenin/vinculin |
| View | Download | 0.451 | a.27.1 | Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases |
| View | Download | 0.450 | a.24.3 | Cytochromes |
| View | Download | 0.446 | f.31.1 | Photosystem I reaction center subunit XI, PsaL |
| View | Download | 0.443 | f.36.1 | Neurotransmitter-gated ion-channel pransmembrane pore |
| View | Download | 0.435 | a.62.1 | Hepatitis B viral capsid (hbcag) |
| View | Download | 0.412 | a.138.1 | Multiheme cytochromes |
| View | Download | 0.410 | a.24.3 | Cytochromes |
| View | Download | 0.398 | a.24.1 | Apolipoprotein |
| View | Download | 0.392 | f.18.1 | F1F0 ATP synthase subunit A |
| View | Download | 0.364 | a.5.4 | Elongation factor TFIIS domain 2 |
| View | Download | 0.352 | a.47.2 | t-snare proteins |
| View | Download | 0.350 | a.29.5 | alpha-ketoacid dehydrogenase kinase, N-terminal domain |
| View | Download | 0.333 | a.78.1 | Fatty acid responsive transcription factor FadR, C-terminal domain |
| View | Download | 0.332 | f.13.1 | Family A G protein-coupled receptor-like |
| View | Download | 0.311 | a.47.2 | t-snare proteins |
| View | Download | 0.297 | f.21.2 | Fumarate reductase respiratory complex transmembrane subunits |
| View | Download | 0.291 | a.7.2 | Enzyme IIa from lactose specific PTS, IIa-lac |
| View | Download | 0.278 | a.24.11 | Bacterial GAP domain |
| View | Download | 0.276 | a.121.1 | Tetracyclin repressor-like, C-terminal domain |
| View | Download | 0.267 | a.63.1 | Apolipophorin-III |
| View | Download | 0.266 | a.26.1 | 4-helical cytokines |
| View | Download | 0.266 | f.1.4 | Bcl-2 inhibitors of programmed cell death |
| View | Download | 0.263 | a.24.9 | alpha-catenin/vinculin |
| View | Download | 0.262 | d.67.3 | Ribosome recycling factor, RRF |
| View | Download | 0.247 | a.172.1 | Helical scaffold and wing domains of SecA |
| View | Download | 0.244 | a.26.1 | 4-helical cytokines |
| View | Download | 0.240 | d.6.1 | Prion-like |
| View | Download | 0.234 | a.24.4 | Hemerythrin |
| View | Download | 0.225 | a.1.1 | Globin-like |
| View | Download | 0.224 | a.1.1 | Globin-like |
| View | Download | 0.224 | c.80.1 | SIS domain |
| View | Download | 0.224 | a.7.7 | BAG domain |
| View | Download | 0.222 | a.19.1 | Fertilization protein |
| View | Download | 0.220 | i.11.1 | Computational models partly based on NMR data |
| View | Download | 0.220 | a.2.6 | Effector domain of the protein kinase pkn/prk1 |
| View | Download | 0.219 | a.1.1 | Globin-like |
| View | Download | 0.215 | a.24.14 | FAT domain of focal adhesion kinase |
| View | Download | 0.212 | a.133.1 | Phospholipase A2, PLA2 |
| View | Download | 0.210 | d.87.2 | CO dehydrogenase flavoprotein C-terminal domain-like |
| View | Download | 0.207 | a.25.1 | Ferritin-like |
| View | Download | 0.207 | d.195.1 | YopH tyrosine phosphatase N-terminal domain |
| View | Download | 0.205 | a.73.1 | Retrovirus capsid protein, N-terminal core domain |
| View | Download | 0.201 | a.170.1 | BRCA2 helical domain |
|
Region A: Residues: [137-209] |
1 11 21 31 41 51
| | | | | |
1 GSNGSFSDHD LLLQYARKSI DLSKIERDLE YISSMPHMSG TSGDAAIRHY IKESFDKNGI 60
61 RLAGEEEFMA YSN
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Region B: Residues: [322-348] |
1 11 21 31 41 51
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1 QYGTGDALTP EWEGSIRDPI DATEAKC
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Region C: Residues: [398-619] |
1 11 21 31 41 51
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1 IRERHPVHDI VGKIEGSEQA GRAIVIAAPR NSASYGTMYP SFGTVVLLSL IQLYQEMVYK 60
61 FDWKPLRNIY FISFGGSEFN EAGATELMEK RTEALKSEIY TIIDVGQIGI WDDSNNLEIQ 120
121 CHPLLVDLFQ KNMTSRKFNV KVDNVHQFGD WTPYLAQGIP VAIISSPGVM NREHPIYTVE 180
181 DKFDFIKDKL RDKKKGEVLS EIMLYLVEKS LELIDDPFIP FS
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| Detection Method: | |
| Confidence: | 277.54902 |
| Match: | 1de4C_ |
| Description: | Transferrin receptor ectodomain, C-terminal domain; Transferrin receptor ectodomain, apical domain; Transferrin receptor ectodomain, protease-like domain |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| peptidase activity | 3.26568153906254 | bayes_pls_golite062009 |
| peptidase activity, acting on L-amino acid peptides | 2.98334117181651 | bayes_pls_golite062009 |
| hydrolase activity | 2.9250662598192 | bayes_pls_golite062009 |
| transmembrane receptor activity | 2.06300314555202 | bayes_pls_golite062009 |
| signal transducer activity | 1.98411113807388 | bayes_pls_golite062009 |
| molecular transducer activity | 1.98411113807388 | bayes_pls_golite062009 |
| receptor activity | 1.93707013781136 | bayes_pls_golite062009 |
| metallopeptidase activity | 1.75261723003176 | bayes_pls_golite062009 |
| exopeptidase activity | 1.5759162922092 | bayes_pls_golite062009 |
| catalytic activity | 1.3989281287879 | bayes_pls_golite062009 |
| transferrin receptor activity | 1.08060244646522 | bayes_pls_golite062009 |
| carboxypeptidase activity | 0.891655769761122 | bayes_pls_golite062009 |
| binding | 0.700980045216992 | bayes_pls_golite062009 |
| metalloexopeptidase activity | 0.472688733072762 | bayes_pls_golite062009 |
| metallocarboxypeptidase activity | 0.180859448845431 | bayes_pls_golite062009 |
| aminopeptidase activity | 0.0966237570696103 | bayes_pls_golite062009 |
|
Region A: Residues: [210-321] |
1 11 21 31 41 51
| | | | | |
1 YPGNVSLRVY SKDDTEGFDI PLNEENFNPM SHNGQLNNIP VIYANKASLD DMASMQDQGL 60
61 LNGDFILLVH YGDYVFQQML TAQEYGAKAI IFISEPYQDN KDVIQMKSVA LP
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|
Region B: Residues: [349-397] |
1 11 21 31 41 51
| | | | | |
1 LPKIPSIPIS ANQGDKILAI LSDTGVKFSN NLFSGSLNDC RLDLLVQTA
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Region C: Residues: [620-783] |
1 11 21 31 41 51
| | | | | |
1 ISNYVDFLST TLKDLQKECP DTVNFDEVFL GTTLWENTKL QFEKWKSEWT ELMYGAGTYI 60
61 EPTIIAINRW SWNYLLSLIG VTQCLEEGLM DRTFYKNVIF GPKLWVDKGD PLRSWTFPEI 120
121 RDTIAIKDWS SVQVQANTLG TILQNTARYF LENKNLHGIN TNEF
|
| Detection Method: | |
| Confidence: | 277.54902 |
| Match: | 1de4C_ |
| Description: | Transferrin receptor ectodomain, C-terminal domain; Transferrin receptor ectodomain, apical domain; Transferrin receptor ectodomain, protease-like domain |
| Matching Structure (courtesy of the PDB): |
|
