YRC Public Data Repository - Protein Structure Prediction

Protein:	TAF13_YEAST
Organism:	Saccharomyces cerevisiae S288c
Length:	167 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TAF13_YEAST.

Description	E-value	Query Range	Subject Range
TAF13_YEAST - Transcription initiation factor TFIID subunit 13 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S... TAF13 - TFIID subunit (19 kDa), involved in RNA polymerase II transcription initiation, similar to histone H...	4.0E-48	[1..167]	[1..167]
gi\|3328173, gi\|3... - gi\|56203973\|emb\|CAI19927.1\| suppressor of Ty 3 homolog (S. cerevisiae) [Homo sapiens], gi\|55957996\|e...	2.0E-47	[3..155]	[18..201]
SPT3_SCHPO - SAGA complex subunit spt3 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=spt3 PE=1 SV=2 spt3 - histone acetyltransferase complex subunit Spt3	2.0E-44	[4..156]	[3..194]
gi\|2253303 - gi\|2253303\|gb\|AAC49995.1\| Spt3 [Schizosaccharomyces pombe]	3.0E-44	[4..156]	[3..194]
Spt3-PA - The gene Spt3 is referred to in FlyBase by the symbol Dmel\Spt3 (CG3169, FBgn0037981). It is a prote...	8.0E-36	[13..156]	[104..267]
gi\|4929173 - gi\|4929173\|gb\|AAD33888.1\|AF142757_1 transcription factor Spt3 [Candida albicans] gi\|46441197, gi\|... - gi\|68473155\|ref\|XP_719383.1\| hypothetical protein CaO19.7622 [Candida albicans SC5314], gi\|46441197\|... gi\|238880407 - gi\|238880407\|gb\|EEQ44045.1\| protein SPT3 [Candida albicans WO-1]	1.0E-31	[8..158]	[6..215]

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Predicted Domain #1

Region A:
Residues: [1-54]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSRKLKKTNL FNKDVSSLLY AYGDVPQPLQ ATVQCLDELV SGYLVDVCTN AFHT

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	14.0
Match:	1bh8A_
Description:	TAF(II)18
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
general RNA polymerase II transcription factor activity	8.88482968293417	bayes_pls_golite062009
DNA binding	4.24660531286828	bayes_pls_golite062009
nucleic acid binding	4.14026521609645	bayes_pls_golite062009
transcription regulator activity	3.91807454227165	bayes_pls_golite062009
transcription initiation factor activity	3.78067108255869	bayes_pls_golite062009
binding	3.14832737946099	bayes_pls_golite062009
RNA polymerase II transcription factor activity	3.02428691626433	bayes_pls_golite062009
transcription factor activity	2.39322722597434	bayes_pls_golite062009
transcription activator activity	1.12739348005764	bayes_pls_golite062009
nucleotidyltransferase activity	1.03060091158028	bayes_pls_golite062009
protein binding	1.01897642648285	bayes_pls_golite062009
transcription factor binding	1.01773884290535	bayes_pls_golite062009
transcription coactivator activity	0.976797801726735	bayes_pls_golite062009
transcription cofactor activity	0.840442755533537	bayes_pls_golite062009
transcription repressor activity	0.621482805601238	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	0.0919482386963733	bayes_pls_golite062009
sequence-specific DNA binding	0.0585868733603467	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [55-167]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AQNSQRNKLR LEDFKFALRK DPIKLGRAEE LIATNKLITE AKKQFNETDN QNSLKRYREE  60
   61 DEEGDEMEED EDEQQVTDDD EEAAGRNSAK QSTDSKATKI RKQGPKNLKK TKK

[Run NCBI BLAST on this sequence.]

Detection Method:	Pfam
Confidence:	5.958607
Match:	PF02269
Description:	Transcription initiation factor IID, 18kD subunit

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: