| Protein: | MKK1_YEAST |
| Organism: | Saccharomyces cerevisiae S288c |
| Length: | 508 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MKK1_YEAST.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..508] | [1..508] |
|
|
0.0 | [31..501] | [100..533] |
|
|
0.0 | [31..503] | [95..534] |
|
|
0.0 | [31..501] | [100..533] |
|
|
0.0 | [31..503] | [95..534] |
|
|
0.0 | [31..503] | [95..534] |
|
Region A: Residues: [1-83] |
1 11 21 31 41 51
| | | | | |
1 MASLFRPPES AKCNPNSPRL KLPLLRNNQV DENNIYLTSN GSSTTAYSSH TPEPLTSSTS 60
61 TLFSQTRLHP SDSSMTLNTM KKR
|
| Detection Method: |  |
| Confidence: | 3.30103 |
| Match: | 1f3mA_ |
| Description: | pak1 autoregulatory domain |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [84-152] |
1 11 21 31 41 51
| | | | | |
1 PAPPSLPSLS INSQSKCKTL PELVPIADVS DGKHDLGLKQ RVIAENELSG NSDLTPSSMA 60
61 SPFSHTNTS
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [153-301] |
1 11 21 31 41 51
| | | | | |
1 SPYLRNDLSN SVGSDFSNLI SAYEQSSSPI KSSSQPKSSS ESYIDLNSVR DVDQLDENGW 60
61 KYANLKDRIE TLGILGEGAG GSVSKCKLKN GSKIFALKVI NTLNTDPEYQ KQIFRELQFN 120
121 RSFQSEYIVR YYGMFTDDEN SSIYIAMEY
|
| Detection Method: | |
| Confidence: | 373.9897 |
| Match: | 1f3mC_ |
| Description: | pak1 |
| Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| phosphotransferase activity, alcohol group as acceptor | 5.49988294224815 | bayes_pls_golite062009 |
| protein kinase activity | 5.4586557943719 | bayes_pls_golite062009 |
| kinase activity | 5.3287080791198 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 4.96052051118534 | bayes_pls_golite062009 |
| cyclin-dependent protein kinase activity | 4.62392503670521 | bayes_pls_golite062009 |
| protein serine/threonine kinase activity | 4.46381887831481 | bayes_pls_golite062009 |
| transferase activity | 3.97138602499442 | bayes_pls_golite062009 |
| binding | 2.74863538127007 | bayes_pls_golite062009 |
| protein binding | 2.276111749106 | bayes_pls_golite062009 |
| tubulin binding | 2.18641675163967 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 2.12615078788254 | bayes_pls_golite062009 |
| ATP binding | 1.97600611746091 | bayes_pls_golite062009 |
| adenyl ribonucleotide binding | 1.93596671856664 | bayes_pls_golite062009 |
| adenyl nucleotide binding | 1.90928021591891 | bayes_pls_golite062009 |
| microtubule binding | 1.88110801192607 | bayes_pls_golite062009 |
| purine ribonucleotide binding | 1.65732943334212 | bayes_pls_golite062009 |
| ribonucleotide binding | 1.65726906484847 | bayes_pls_golite062009 |
| purine nucleotide binding | 1.63763394711025 | bayes_pls_golite062009 |
| nucleotide binding | 1.63195828048121 | bayes_pls_golite062009 |
| transcription regulator activity | 1.56748951434625 | bayes_pls_golite062009 |
| nucleic acid binding | 1.46547714006072 | bayes_pls_golite062009 |
| MAP kinase kinase activity | 1.42275431028856 | bayes_pls_golite062009 |
| protein tyrosine kinase activity | 1.3898059094397 | bayes_pls_golite062009 |
| receptor signaling protein serine/threonine kinase activity | 1.38496328649031 | bayes_pls_golite062009 |
| DNA binding | 1.35333135345112 | bayes_pls_golite062009 |
| actin binding | 1.33479685165255 | bayes_pls_golite062009 |
| gamma-tubulin binding | 1.28511591054866 | bayes_pls_golite062009 |
| receptor signaling protein activity | 1.27291233344322 | bayes_pls_golite062009 |
| catalytic activity | 1.21655087018101 | bayes_pls_golite062009 |
| structural constituent of muscle | 1.19908793854422 | bayes_pls_golite062009 |
| transcription repressor activity | 1.14496167267281 | bayes_pls_golite062009 |
| transcription factor activity | 1.10928254946881 | bayes_pls_golite062009 |
| telethonin binding | 1.04264263421201 | bayes_pls_golite062009 |
| transcription activator activity | 0.997272622653026 | bayes_pls_golite062009 |
| MAP kinase activity | 0.81943579965027 | bayes_pls_golite062009 |
| structural constituent of cytoskeleton | 0.612883428421652 | bayes_pls_golite062009 |
| transporter activity | 0.553953601841147 | bayes_pls_golite062009 |
| protein serine/threonine/tyrosine kinase activity | 0.48345772948903 | bayes_pls_golite062009 |
| enzyme binding | 0.46284745266176 | bayes_pls_golite062009 |
| kinase binding | 0.443916188551908 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity | 0.401250804041384 | bayes_pls_golite062009 |
| magnesium ion binding | 0.393328812780268 | bayes_pls_golite062009 |
| transmembrane transporter activity | 0.37676337669549 | bayes_pls_golite062009 |
| MAP kinase kinase kinase activity | 0.37115026509016 | bayes_pls_golite062009 |
| protein kinase binding | 0.285611963740145 | bayes_pls_golite062009 |
| signal transducer activity | 0.270054246024761 | bayes_pls_golite062009 |
| molecular transducer activity | 0.270054246024761 | bayes_pls_golite062009 |
| actin filament binding | 0.2403700250846 | bayes_pls_golite062009 |
| alpha-actinin binding | 0.181804774839734 | bayes_pls_golite062009 |
| protein complex binding | 0.132247221889251 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 0.0611721261859464 | bayes_pls_golite062009 |
| transmembrane receptor protein kinase activity | 0.0556163711947139 | bayes_pls_golite062009 |
| transmembrane receptor activity | 0.00652065412910241 | bayes_pls_golite062009 |
|
Region A: Residues: [302-508] |
1 11 21 31 41 51
| | | | | |
1 MGGRSLDAIY KNLLERGGRI SEKVLGKIAE AVLRGLSYLH EKKVIHRDIK PQNILLNENG 60
61 QVKLCDFGVS GEAVNSLATT FTGTSFYMAP ERIQGQPYSV TSDVWSLGLT ILEVANGKFP 120
121 CSSEKMAANI APFELLMWIL TFTPELKDEP ESNIIWSPSF KSFIDYCLKK DSRERPSPRQ 180
181 MINHPWIKGQ MKKNVNMEKF VRKCWKD
|
| Detection Method: | |
| Confidence: | 373.9897 |
| Match: | 1f3mC_ |
| Description: | pak1 |
| Matching Structure (courtesy of the PDB): |
|
